Gene Hung

11.4k citations

69 papers · 8.7k · 7 hit papers · h-index 37

Impact in

Genetics top 0.2%
- Neurogenetic and Muscular Disorders Research
Cancer Research top 0.5%
- Cancer-related molecular mechanisms research

Papers in

Molecular Biology 43
- RNA Research and Splicing 12
- RNA modifications and cancer 9
- Muscle Physiology and Disorders 8
Cellular and Molecular Neuroscience 17
- Genetic Neurodegenerative Diseases 16

Co-authors: C. Frank Bennett (18 shared papers)Frank Rigo (11 shared papers)Adrian R. Krainer (6 shared papers)Yimin Hua (6 shared papers)Kentaro Sahashi (5 shared papers)David L. Spector (3 shared papers)Gayatri Arun (3 shared papers)Marco A. Passini (2 shared papers)
Journals: Neurology (4 papers)Cancer Research (4 papers)Nucleic Acids Research (3 papers)Blood (3 papers)International Journal of Oncology (3 papers)
Partner nations: United States Germany Canada

In The Last Decade

Gene Hung

67 papers receiving 8.6k citations

Gene Hung's Hit Papers

7 papers align trajectories log scale

Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study 2016 · 747 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2016 The Lancet
2012 Cancer Research
2012 Cell Reports
2012 Neuron
2011 Nature
2010 Genes & Development
1997 Journal of Clinical Oncology

Peers

Countries citing papers authored by Gene Hung

Since Specialization

Citations

This map shows the geographic impact of Gene Hung's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gene Hung with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gene Hung more than expected).

Fields of papers citing papers by Gene Hung

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gene Hung. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gene Hung. The network helps show where Gene Hung may publish in the future.

Co-authors

The 25 scholars most cited alongside Gene Hung, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Gene Hung Line = papers co-authored together Gene Hung links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 69 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells Cancer Research ·Tony Gutschner, Monika Hämmerle, Moritz F. Eissmann, Jeff Hsu, Youngsoo Kim, Gene Hung, Alexey S. Revenko, Gayatri Arun, Marion Stentrup, Matthias Groß, Martin Zörnig, A. Robert MacLeod, David L. Spector, Sven Diederichs Hit paper breakdown →	2012	1323
2	Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study The Lancet ·Richard S. Finkel, Claudia A. Chiriboga, Jiri Vajsar, (unknown), Jacqueline Montes, Darryl C. De Vivo, Mason Yamashita, Frank Rigo, Gene Hung, Eugene Schneider, (unknown), Shuting Xia, C. Frank Bennett, Kathie M. Bishop Hit paper breakdown →	2016	747
3	HER-2/neu gene amplification characterized by fluorescence in situ hybridization: poor prognosis in node-negative breast carcinomas. Journal of Clinical Oncology ·Michael F. Press, Leslie Bernstein, P. Thomas, L F Meisner, Jian Zhou, Yanhui Ma, Gene Hung, Robert A. Robinson, C Harris, Adel K. El‐Naggar, Dennis J. Slamon, R N Phillips, Jeffrey S. Ross, S R Wolman, Kerry Flom Hit paper breakdown →	1997	644
4	Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis Neuron ·Holly Kordasiewicz, Lisa M. Stanek, Edward V. Wancewicz, Curt Mazur, Melissa McAlonis, Kimberly A. Pytel, Jonathan W. Artates, Andreas Weiss, Seng H. Cheng, Lamya S. Shihabuddin, Gene Hung, C. Frank Bennett, Don W. Cleveland Hit paper breakdown →	2012	570
5	Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model Nature ·Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung, Guy Horev, C. Frank Bennett, Adrian R. Krainer Hit paper breakdown →	2011	560
6	Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model Genes & Development ·Yimin Hua, Kentaro Sahashi, Gene Hung, Frank Rigo, Marco A. Passini, C. Frank Bennett, Adrian R. Krainer Hit paper breakdown →	2010	505
7	The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult Cell Reports ·Bin Zhang, Gayatri Arun, Yuntao S. Mao, Zsolt I. Lázár, Gene Hung, Gourab Bhattacharjee, Xiaokun Xiao, Carmen J. Booth, Jie Wu, Chaolin Zhang, David L. Spector Hit paper breakdown →	2012	500
8	Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy Science Translational Medicine ·Marco A. Passini, Jie Bu, Amy M. Richards, Cathrine Kinnecom, S. Pablo Sardi, Lisa M. Stanek, Yimin Hua, Frank Rigo, John Matson, Gene Hung, Edward M. Kaye, Lamya S. Shihabuddin, Adrian R. Krainer, C. Frank Bennett, Seng H. Cheng	2011	418
9	Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals Nucleic Acids Research ·Eric E. Swayze, Andrew Siwkowski, Edward V. Wancewicz, Michael T. Migawa, Tadeusz K. Wyrzykiewicz, Gene Hung, Brett P. Monia, and C. Frank Bennett	2006	362
10	Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin Molecular Therapy ·Jeffrey B. Carroll, Simon C. Warby, Amber L. Southwell, Crystal N. Doty, Sarah Greenlee, Niels H. Skotte, Gene Hung, C. Frank Bennett, Susan M. Freier, Michael R. Hayden	2011	227
11	Antisense oligonucleotide therapy for spinocerebellar ataxia type 2 Nature ·Daniel R. Scoles, Pratap Meera, Matthew Schneider, Sharan Paul, Warunee Dansithong, Karla P. Figueroa, Gene Hung, Frank Rigo, C. Frank Bennett, Thomas S. Otis, Stefan M. Pulst	2017	225
12	Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates Journal of Pharmacology and Experimental Therapeutics ·Frank Rigo, Seung Chun, Daniel A. Norris, Gene Hung, Sam Lee, John Matson, Robert Fey, Hans Gaus, Yimin Hua, John S. Grundy, Adrian R. Krainer, Scott P. Henry, C. Frank Bennett	2014	218
13	Amplification and overexpression of HER-2/neu in carcinomas of the salivary gland: correlation with poor prognosis. PubMed ·Michael F. Press, Malcolm C. Pike, Gene Hung, Jian Zhou, Yanling Ma, Jay George, Jeanne Dietz‐Band, William James, Dennis J. Slamon, John G. Batsakis	1994	176
14	Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts Nucleic Acids Research ·Sebastien A. Burel, Christopher E. Hart, Patrick Cauntay, Jill Hsiao, Todd Machemer, Melanie Katz, Andy Watt, Huynh‐Hoa Bui, Husam S. Younis, Mahyar Sabripour, Susan M. Freier, Gene Hung, Amy Dan, Thazha P. Prakash, Punit P. Seth, Eric E. Swayze, C. Frank Bennett, Stanley T. Crooke, Scott P. Henry	2015	155
15	Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy Cell Reports ·Andrew P. Lieberman, Zhigang Yu, Sue Murray, Raechel Peralta, Audrey Low, Shuling Guo, Xing Yu, Constanza J. Cortés, C. Frank Bennett, Brett P. Monia, Albert R. La Spada, Gene Hung	2014	129
16	Muscle Expression of Mutant Androgen Receptor Accounts for Systemic and Motor Neuron Disease Phenotypes in Spinal and Bulbar Muscular Atrophy Neuron ·Constanza J. Cortés, Shuo‐Chien Ling, Ling Guo, Gene Hung, Taiji Tsunemi, Linda Ly, Seiya Tokunaga, Edith Lopez, Bryce L. Sopher, C. Frank Bennett, G. Diane Shelton, Don W. Cleveland, Albert R. La Spada	2014	126
17	PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models Journal of Clinical Investigation ·Hien Zhao, Sagar Damle, Karli Ikeda-Lee, Steven Kuntz, Jian Li, Apoorva Mohan, Aneeza Kim, Gene Hung, Mark A. Scheideler, Steven S. Scherer, John Svaren, Eric E. Swayze, Holly Kordasiewicz	2017	121
18	Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model Journal of Neuroscience ·Jun Wu, Daniel A. Ryskamp, Xia Liang, Polina A. Egorova, О. А. Захарова, Gene Hung, Ilya Bezprozvanny	2016	114
19	Characterization of Target mRNA Reduction Through In Situ RNA Hybridization in Multiple Organ Systems Following Systemic Antisense Treatment in Animals Nucleic Acid Therapeutics ·Gene Hung, Xiaokun Xiao, Raechel Peralta, Gourab Bhattacharjee, Sue Murray, Dan Norris, Shuling Guo, Brett P. Monia	2013	101
20	Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models Molecular Therapy — Nucleic Acids ·Lauren R. Moore, Gautam Rajpal, Ian T. Dillingham, Maya Qutob, Kate G. Blumenstein, Danielle Gattis, Gene Hung, Holly Kordasiewicz, Henry L. Paulson, Hayley S. McLoughlin	2017	91

About Gene Hung

Gene Hung is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Genetics, Neurology and Cancer Research, having authored 69 papers that have together received 8.7k indexed citations. Recurring topics across this work include Genetic Neurodegenerative Diseases (16 papers), RNA Research and Splicing (12 papers), Neurogenetic and Muscular Disorders Research (12 papers), RNA modifications and cancer (9 papers), Neurofibromatosis and Schwannoma Cases (8 papers), Muscle Physiology and Disorders (8 papers), Cancer-related molecular mechanisms research (5 papers) and Virus-based gene therapy research (5 papers). The work is most often cited by research in Genetics (2.2k citations), Cancer Research (2.0k citations), Molecular Biology (6.1k citations), Cellular and Molecular Neuroscience (1.5k citations) and Neurology (765 citations). Gene Hung has collaborated with scholars based in United States, Germany and Canada. Frequent co-authors include C. Frank Bennett, Frank Rigo, Adrian R. Krainer, Yimin Hua, Kentaro Sahashi, David L. Spector, Gayatri Arun, Marco A. Passini, A. Robert MacLeod and Jeff Hsu. Their work appears in journals such as Neurology, Cancer Research, Nucleic Acids Research, Blood and International Journal of Oncology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Gene Hung

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In The Last Decade

Gene Hung

Gene Hung's Hit Papers

Peers

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Fields of papers citing papers by Gene Hung

All Works

About Gene Hung

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