Michael E. Østergaard

2.9k citations
49 papers · 2.1k · h-index 25

Impact in

  • Molecular Biology top 5%
    • Advanced biosensing and bioanalysis techniques
    • DNA and Nucleic Acid Chemistry
    • RNA Interference and Gene Delivery
    • RNA and protein synthesis mechanisms
    • RNA Research and Splicing
    • CRISPR and Genetic Engineering
    • Mitochondrial Function and Pathology
  • Cellular and Molecular Neuroscience top 5%
    • Genetic Neurodegenerative Diseases

Papers in

  • Molecular Biology 49
    • DNA and Nucleic Acid Chemistry 34
    • Advanced biosensing and bioanalysis techniques 31
    • RNA Interference and Gene Delivery 28
    • RNA and protein synthesis mechanisms 7
    • RNA Research and Splicing 6
    • Muscle Physiology and Disorders 4
  • Organic Chemistry 7
    • Carbohydrate Chemistry and Synthesis 5
Co-authors
Patrick J. Hrdlicka (17 shared papers)Punit P. Seth (30 shared papers)Eric E. Swayze (24 shared papers)Hans Gaus (5 shared papers)Audrey Low (7 shared papers)Michael R. Hayden (6 shared papers)Amber L. Southwell (6 shared papers)Crystal N. Doty (5 shared papers)
Journals
Nucleic Acids Research (8 papers)The Journal of Organic Chemistry (7 papers)Bioorganic & Medicinal Chemistry Letters (7 papers)Angewandte Chemie International Edition (2 papers)Chemical Communications (2 papers)
Partner nations
United StatesCanadaIndia

In The Last Decade

Michael E. Østergaard

49 papers receiving 2.1k citations

Peers

Michael E. Østergaard
Comparison fields: 5 of 84
  • Molecular Biology 1.8k
  • Cellular and Molecular Neuroscience 345
  • Genetics 108
  • Organic Chemistry 202
  • Neurology 87
Replace Andreas Kremer with:
Andreas Kremer Netherlands
Christian Jüngst Germany
Jamie Longgood United States
Coby B. Carlson United States
P. Andrew Chong Canada
Janelle Lauer United States
Rula Zain Sweden
Rebecca L. Maglathlin United States
Ginny I. Chen Canada
Peter M. Clark United States
Michael E. Østergaard relative to Andreas Kremer Netherlands Andreas Kremer's profile →
Citations per field
00.5×2×4×5.5×
Andreas Kremer · 1×
Citations per year

Countries citing papers authored by Michael E. Østergaard

Since Specialization
Citations

This map shows the geographic impact of Michael E. Østergaard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael E. Østergaard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael E. Østergaard more than expected).

Fields of papers citing papers by Michael E. Østergaard

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael E. Østergaard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael E. Østergaard. The network helps show where Michael E. Østergaard may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael E. Østergaard, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael E. Østergaard Line = papers co-authored together Michael E. Østergaard links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 49 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): Tools for fundamental research, diagnostics, and nanotechnology
Chemical Society Reviews ·Michael E. Østergaard, Patrick J. Hrdlicka
2011239
2
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
Nucleic Acids Research ·Colton M. Miller, Aaron J. Donner, Emma E Blank, Andrew Egger, Brianna M. Kellar, Michael E. Østergaard, Punit P. Seth, Edward N. Harris
2016142
3
Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS
Nucleic Acids Research ·Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz, Andrew T. Watt, Niels H. Skotte, Crystal N. Doty, Kuljeet Vaid, Erika B. Villanueva, Eric E. Swayze, C. Frank Bennett, Michael R. Hayden, Punit P. Seth
2013130
4
Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay
Nucleic Acids Research ·Hans Gaus, Ruchi Gupta, Alfred E. Chappell, Michael E. Østergaard, Eric E. Swayze, Punit P. Seth
2018119
5
Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle
Nucleic Acids Research ·Thazha P. Prakash, Adam E. Mullick, Richard Lee, Jinghua Yu, Steve T. Yeh, Audrey Low, Alfred E. Chappell, Michael E. Østergaard, Sue Murray, Hans Gaus, Eric E. Swayze, Punit P. Seth
2019113
6
In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides
Molecular Therapy ·Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz, Michael E. Østergaard, Andrew T. Watt, Jeffrey B. Carroll, Crystal N. Doty, Erika B. Villanueva, Eugenia Petoukhov, Kuljeet Vaid, Yuanyun Xie, Susan M. Freier, Eric E. Swayze, Punit P. Seth, Clarence Frank Bennett, Michael R. Hayden
2014112
7
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides
Nucleic Acids Research ·Brooke A. Anderson, Graeme C. Freestone, Audrey Low, Cheryl L De-Hoyos, William J. Drury, Michael E. Østergaard, Michael T. Migawa, Michael Fazio, (unknown), Andrés Berdeja, Eli Scandalis, Sebastien A. Burel, Timothy A. Vickers, Stanley T. Crooke, Eric E. Swayze, Xue‐hai Liang, Punit P. Seth
2021100
8
Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease
Science Translational Medicine ·Amber L. Southwell, Holly Kordasiewicz, Douglas R. Langbehn, Niels H. Skotte, Matthew P. Parsons, Erika B. Villanueva, Nicholas S. Caron, Michael E. Østergaard, Lisa M. Anderson, Yuanyun Xie, Louisa Dal Cengio, Hailey Findlay Black, Crystal N. Doty, Bethany Fitsimmons, Eric E. Swayze, Punit P. Seth, Lynn A. Raymond, C. Frank Bennett, Michael R. Hayden
201894
9
HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity
Human Molecular Genetics ·Virginia B. Mattis, Colton M. Tom, Sergey Akimov, Jasmine Saeedian, Michael E. Østergaard, Amber L. Southwell, Crystal N. Doty, Loren Ornelas, Anais Sahabian, Lindsay Lenaeus, Berhan Mandefro, Dhruv Sareen, Jamshid Arjomand, Michael R. Hayden, Christopher A. Ross, Clive N. Svendsen
201592
10
Allele-Specific Suppression of Mutant Huntingtin Using Antisense Oligonucleotides: Providing a Therapeutic Option for All Huntington Disease Patients
PLoS ONE ·Niels H. Skotte, Amber L. Southwell, Michael E. Østergaard, Jeffrey B. Carroll, Simon C. Warby, Crystal N. Doty, Eugenia Petoukhov, Kuljeet Vaid, Holly Kordasiewicz, Andrew T. Watt, Susan M. Freier, Gene Hung, Punit P. Seth, C. Frank Bennett, Eric E. Swayze, Michael R. Hayden
201490
11
Understanding the effect of controlling phosphorothioate chirality in the DNA gap on the potency and safety of gapmer antisense oligonucleotides
Nucleic Acids Research ·Michael E. Østergaard, Cheryl Li De Hoyos, (unknown), Wen Shen, Audrey Low, Andrés Berdeja, Guillermo Vasquez, Susan Murray, Michael T. Migawa, Xue‐hai Liang, Eric E. Swayze, Stanley T. Crooke, Punit P. Seth
202078
12
Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor
Nucleic Acids Research ·Karsten Schmidt, Thazha P. Prakash, Aaron J. Donner, Garth A. Kinberger, Hans Gaus, Audrey Low, Michael E. Østergaard, Melanie Bell, Eric E. Swayze, Punit P. Seth
201777
13
Efficient Synthesis and Biological Evaluation of 5′-GalNAc Conjugated Antisense Oligonucleotides
Bioconjugate Chemistry ·Michael E. Østergaard, Jinghua Yu, Garth A. Kinberger, (unknown), Michael T. Migawa, Guillermo Vasquez, Karsten Schmidt, Hans Gaus, Heather Murray, Audrey Low, Eric E. Swayze, Thazha P. Prakash, Punit P. Seth
201565
14
Glowing Locked Nucleic Acids: Brightly Fluorescent Probes for Detection of Nucleic Acids in Cells
Journal of the American Chemical Society ·Michael E. Østergaard, Pallavi Cheguru, Madhusudhan R. Papasani, Rodney A. Hill, Patrick J. Hrdlicka
201046
15
Pyrene-functionalized triazole-linked 2′-deoxyuridines—probes for discrimination of single nucleotide polymorphisms (SNPs)
Chemical Communications ·Michael E. Østergaard, Dale C. Guenther, Pawan Kumar, Bharat Baral, Lee A. Deobald, Andrzej Paszczyński, Pawan K. Sharma, Patrick J. Hrdlicka
201040
16
Functionalized 2′-Amino-α-L-LNA: Directed Positioning of Intercalators for DNA Targeting
The Journal of Organic Chemistry ·T. Santhosh Kumar, Andreas S. Madsen, Michael E. Østergaard, Sujay P. Sau, Jesper Wengel, Patrick J. Hrdlicka
200839
17
Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2′-Fluoro RNA
The Journal of Organic Chemistry ·Punit P. Seth, Jinghua Yu, Ali Jazayeri, Pradeep S. Pallan, Charles Allerson, Michael E. Østergaard, Feng‐Wu Liu, Piet Herdewijn, Martin Egli, Eric E. Swayze
201237
18
Site-specific incorporation of 5′-methyl DNA enhances the therapeutic profile of gapmer ASOs
Nucleic Acids Research ·Guillermo Vasquez, Graeme C. Freestone, (unknown), Audrey Low, Cheryl Li De Hoyos, Jinghua Yu, Thazha P. Prakash, Michael E. Østergaard, Xue‐hai Liang, Stanley T. Crooke, Eric E. Swayze, Michael T. Migawa, Punit P. Seth
202137
19
Nucleic Acid Structural Engineering Using Pyrene-Functionalized 2′-Amino-α-L-LNA Monomers and Abasic Sites
The Journal of Organic Chemistry ·T. Santhosh Kumar, Andreas S. Madsen, Michael E. Østergaard, Jesper Wengel, Patrick J. Hrdlicka
200835
20
C5‐Functionalized DNA, LNA, and α‐L‐LNA: Positional Control of Polarity‐Sensitive Fluorophores Leads to Improved SNP‐Typing
Chemistry - A European Journal ·Michael E. Østergaard, Pawan Kumar, Bharat Baral, Dale C. Guenther, Brooke A. Anderson, F. Marty Ytreberg, Lee A. Deobald, Andrzej Paszczyński, Pawan K. Sharma, Patrick J. Hrdlicka
201131

About Michael E. Østergaard

Michael E. Østergaard is a scholar working on Molecular Biology, Organic Chemistry, Cellular and Molecular Neuroscience, Pharmaceutical Science and Nephrology, having authored 49 papers that have together received 2.1k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (34 papers), Advanced biosensing and bioanalysis techniques (31 papers), RNA Interference and Gene Delivery (28 papers), RNA and protein synthesis mechanisms (7 papers), Genetic Neurodegenerative Diseases (6 papers), RNA Research and Splicing (6 papers), Carbohydrate Chemistry and Synthesis (5 papers) and Muscle Physiology and Disorders (4 papers). The work is most often cited by research in Molecular Biology (1.8k citations), Cellular and Molecular Neuroscience (345 citations), Genetics (108 citations), Organic Chemistry (202 citations) and Neurology (87 citations). Michael E. Østergaard has collaborated with scholars based in United States, Canada and India. Frequent co-authors include Patrick J. Hrdlicka, Punit P. Seth, Eric E. Swayze, Hans Gaus, Audrey Low, Michael R. Hayden, Amber L. Southwell, Crystal N. Doty, Alfred E. Chappell and Thazha P. Prakash. Their work appears in journals such as Nucleic Acids Research, The Journal of Organic Chemistry, Bioorganic & Medicinal Chemistry Letters, Angewandte Chemie International Edition and Chemical Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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