Eric E. Swayze

14.5k citations

190 papers · 10.4k · 2 hit papers · h-index 54

Impact in

Molecular Biology top 0.5%
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- DNA and Nucleic Acid Chemistry
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- CRISPR and Genetic Engineering
Cancer Research top 1%
- MicroRNA in disease regulation

Papers in

Molecular Biology 155
- DNA and Nucleic Acid Chemistry 74
- RNA Interference and Gene Delivery 60
- Advanced biosensing and bioanalysis techniques 57
- RNA and protein synthesis mechanisms 45
- Chemical Synthesis and Analysis 16
- RNA Research and Splicing 15
Organic Chemistry 41
- Carbohydrate Chemistry and Synthesis 15

Co-authors: C. Frank Bennett (22 shared papers)Punit P. Seth (70 shared papers)Thazha P. Prakash (45 shared papers)Hans Gaus (27 shared papers)Michael T. Migawa (32 shared papers)Richard H. Griffey (28 shared papers)Balkrishen Bhat (22 shared papers)Charles Allerson (16 shared papers)
Journals: Nucleic Acids Research (24 papers)Bioorganic & Medicinal Chemistry Letters (21 papers)Journal of Medicinal Chemistry (15 papers)The Journal of Organic Chemistry (9 papers)Molecular Therapy — Nucleic Acids (8 papers)
Partner nations: United States Canada France

In The Last Decade

Eric E. Swayze

186 papers receiving 10.2k citations

Eric E. Swayze's Hit Papers

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Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice 2014 · 479 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2014 Nucleic Acids Research
2010 The Annual Review of Pharmacology and Toxicology

Peers

Countries citing papers authored by Eric E. Swayze

Since Specialization

Citations

This map shows the geographic impact of Eric E. Swayze's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric E. Swayze with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric E. Swayze more than expected).

Fields of papers citing papers by Eric E. Swayze

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric E. Swayze. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric E. Swayze. The network helps show where Eric E. Swayze may publish in the future.

Co-authors

The 25 scholars most cited alongside Eric E. Swayze, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Eric E. Swayze Line = papers co-authored together Eric E. Swayze links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 190 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform The Annual Review of Pharmacology and Toxicology ·C. Frank Bennett, Eric E. Swayze Hit paper breakdown →	2010	1092
2	Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice Nucleic Acids Research ·Thazha P. Prakash, Mark J. Graham, Jinghua Yu, Rick Carty, Audrey Low, Alfred E. Chappell, Karsten Schmidt, Chenguang Zhao, Mariam Aghajan, Heather F. Murray, Stan Riney, Sheri Booten, Susan Murray, Hans Gaus, Jeff Crosby, Walt F. Lima, Shuling Guo, Brett P. Monia, Eric E. Swayze, Punit P. Seth Hit paper breakdown →	2014	479
3	Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy Science Translational Medicine ·Sarah L. DeVos, Rebecca L. Miller, Kathleen M. Schoch, Brandon B. Holmes, Carey S. Kebodeaux, Amy J. Wegener, Guo Chen, Tao Shen, Hien Tran, Brandon Nichols, Tom Zanardi, Holly Kordasiewicz, Eric E. Swayze, C. Frank Bennett, Marc I. Diamond, Timothy M. Miller	2017	374
4	Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals Nucleic Acids Research ·Eric E. Swayze, Andrew Siwkowski, Edward V. Wancewicz, Michael T. Migawa, Tadeusz K. Wyrzykiewicz, Gene Hung, Brett P. Monia, and C. Frank Bennett	2006	362
5	Fully 2‘-Modified Oligonucleotide Duplexes with Improved in Vitro Potency and Stability Compared to Unmodified Small Interfering RNA Journal of Medicinal Chemistry ·Charles Allerson, Namir Sioufi, Russell Jarres, Thazha P. Prakash, Nishant Naik, Andrés Berdeja, Lisa Wanders, Richard H. Griffey, Eric E. Swayze, Balkrishen Bhat	2005	354
6	Pharmacology of Antisense Drugs The Annual Review of Pharmacology and Toxicology ·C. Frank Bennett, Brenda F. Baker, Nguyen C. Pham, Eric E. Swayze, Richard S. Geary	2016	326
7	Positional Effect of Chemical Modifications on Short Interference RNA Activity in Mammalian Cells Journal of Medicinal Chemistry ·Thazha P. Prakash, Charles Allerson, Prasad Dande, Timothy A. Vickers, Namir Sioufi, Russell Jarres, Brenda F. Baker, Eric E. Swayze, Richard H. Griffey, Balkrishen Bhat	2005	226
8	Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression Cell ·Dongbo Yu, Hannah M. Pendergraff, Jing Liu, Holly Kordasiewicz, Don W. Cleveland, Eric E. Swayze, Walt F. Lima, Stanley T. Crooke, Thazha P. Prakash, David R. Corey	2012	222
9	Short Antisense Oligonucleotides with Novel 2′−4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals Journal of Medicinal Chemistry ·Punit P. Seth, Andrew Siwkowski, Charles Allerson, Guillermo Vasquez, Sam Lee, Thazha P. Prakash, Edward V. Wancewicz, Donna Witchell, Eric E. Swayze	2008	211
10	Single-Stranded siRNAs Activate RNAi in Animals Cell ·Walt F. Lima, Thazha P. Prakash, Heather Murray, Garth A. Kinberger, Wenyu Li, Alfred E. Chappell, Cheryl Li, Susan Murray, Hans Gaus, Punit P. Seth, Eric E. Swayze, Stanley T. Crooke	2012	209
11	Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models Journal of Clinical Investigation ·Alex McCampbell, Tracy Cole, Amy J. Wegener, Giulio Srubek Tomassy, Amy Setnicka, Brandon J. Farley, Kathleen M. Schoch, Mariah L. Hoye, Mark Shabsovich, Linhong Sun, Yi Luo, Mingdi Zhang, Sai Thankamony, David W. Salzman, Merit Cudkowicz, Danielle Graham, C. Frank Bennett, Holly Kordasiewicz, Eric E. Swayze, Timothy M. Miller	2018	188
12	Synthesis and Biophysical Evaluation of 2′,4′-Constrained 2′O-Methoxyethyl and 2′,4′-Constrained 2′O-Ethyl Nucleic Acid Analogues The Journal of Organic Chemistry ·Punit P. Seth, Guillermo Vasquez, Charles A. Allerson, Andrés Berdeja, Hans Gaus, Garth A. Kinberger, Thazha P. Prakash, Michael T. Migawa, Balkrishen Bhat, Eric E. Swayze	2010	165
13	Potent inhibition of microRNA in vivo without degradation Nucleic Acids Research ·Scott Davis, Stephanie Propp, Susan M. Freier, Laura Jones, Martin J. Serra, Garth A. Kinberger, Balkrishen Bhat, Eric E. Swayze, C. Frank Bennett, Christine Esau	2008	164
14	LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson’s Disease Mouse Model Molecular Therapy — Nucleic Acids ·Hien Zhao, Neena John, Vedad Delic, Karli Ikeda-Lee, Aneeza Kim, Andreas Weihofen, Eric E. Swayze, Holly Kordasiewicz, Andrew B. West, Laura A. Volpicelli‐Daley	2017	159
15	Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts Nucleic Acids Research ·Sebastien A. Burel, Christopher E. Hart, Patrick Cauntay, Jill Hsiao, Todd Machemer, Melanie Katz, Andy Watt, Huynh‐Hoa Bui, Husam S. Younis, Mahyar Sabripour, Susan M. Freier, Gene Hung, Amy Dan, Thazha P. Prakash, Punit P. Seth, Eric E. Swayze, C. Frank Bennett, Stanley T. Crooke, Scott P. Henry	2015	155
16	Synthetic CRISPR RNA-Cas9–guided genome editing in human cells Proceedings of the National Academy of Sciences ·Meghdad Rahdar, Moira A. McMahon, Thazha P. Prakash, Eric E. Swayze, C. Frank Bennett, Don W. Cleveland	2015	152
17	SAR by MS: Discovery of a New Class of RNA-Binding Small Molecules for the Hepatitis C Virus: Internal Ribosome Entry Site IIA Subdomain Journal of Medicinal Chemistry ·Punit P. Seth, Alycia Miyaji, Elizabeth A. Jefferson, Kristin A. Sannes‐Lowery, Stephen A. Osgood, Stephanie Propp, Ray Ranken, Christian Massire, Rangarajan Sampath, David J. Ecker, Eric E. Swayze, Richard H. Griffey	2005	136
18	Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS Nucleic Acids Research ·Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz, Andrew T. Watt, Niels H. Skotte, Crystal N. Doty, Kuljeet Vaid, Erika B. Villanueva, Eric E. Swayze, C. Frank Bennett, Michael R. Hayden, Punit P. Seth	2013	124
19	PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models Journal of Clinical Investigation ·Hien Zhao, Sagar Damle, Karli Ikeda-Lee, Steven Kuntz, Jian Li, Apoorva Mohan, Aneeza Kim, Gene Hung, Mark A. Scheideler, Steven S. Scherer, John Svaren, Eric E. Swayze, Holly Kordasiewicz	2017	121
20	Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay Nucleic Acids Research ·Hans Gaus, Ruchi Gupta, Alfred E. Chappell, Michael E. Østergaard, Eric E. Swayze, Punit P. Seth	2018	116

About Eric E. Swayze

Eric E. Swayze is a scholar working on Molecular Biology, Organic Chemistry, Cellular and Molecular Neuroscience, Genetics and Cardiology and Cardiovascular Medicine, having authored 190 papers that have together received 10.4k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (74 papers), RNA Interference and Gene Delivery (60 papers), Advanced biosensing and bioanalysis techniques (57 papers), RNA and protein synthesis mechanisms (45 papers), Genetic Neurodegenerative Diseases (17 papers), Chemical Synthesis and Analysis (16 papers), Carbohydrate Chemistry and Synthesis (15 papers) and RNA Research and Splicing (15 papers). The work is most often cited by research in Molecular Biology (8.3k citations), Cancer Research (1.1k citations), Cellular and Molecular Neuroscience (1.3k citations), Genetics (698 citations) and Neurology (656 citations). Eric E. Swayze has collaborated with scholars based in United States, Canada and France. Frequent co-authors include C. Frank Bennett, Punit P. Seth, Thazha P. Prakash, Hans Gaus, Michael T. Migawa, Richard H. Griffey, Balkrishen Bhat, Charles Allerson, Holly Kordasiewicz and Andrés Berdeja. Their work appears in journals such as Nucleic Acids Research, Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, The Journal of Organic Chemistry and Molecular Therapy — Nucleic Acids.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Eric E. Swayze

Eric E. Swayze's Hit Papers

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Fields of papers citing papers by Eric E. Swayze

All Works

About Eric E. Swayze

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