David Sinclair
Impact in
- Geriatrics and Gerontology top 0.01%
- Sirtuins and Resveratrol in Medicine
- Aging top 0.01%
- Genetics, Aging, and Longevity in Model Organisms
Papers in
-
- Mitochondrial Function and Pathology 25
- DNA Repair Mechanisms 16
-
- Sirtuins and Resveratrol in Medicine 102
- Co-authors
- Joseph A. Baur (12 shared papers)Leonard Guarente (10 shared papers)Haim Cohen (8 shared papers)Shaday Michán (12 shared papers)Marcia C. Haigis (1 shared paper)Kevin J. Bitterman (8 shared papers)Konrad T. Howitz (5 shared papers)Jason G. Wood (8 shared papers)
- Journals
- Cochrane Database of Systematic Reviews (23 papers)Journal of Clinical Pathology (9 papers)Cell (8 papers)Annals of Clinical Biochemistry International Journal of Laboratory Medicine (8 papers)Cell Metabolism (8 papers)
- Partner nations
- United StatesUnited KingdomAustralia
In The Last Decade
David Sinclair
369 papers receiving 46.2k citations
David Sinclair's Hit Papers
Peers
Comparison fields: 5 of 219
- Geriatrics and Gerontology 17.8k
- Aging 6.4k
- Physiology 3.8k
- Physiology 13.5k
- Biological Psychiatry 934
Countries citing papers authored by David Sinclair
This map shows the geographic impact of David Sinclair's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Sinclair with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Sinclair more than expected).
Fields of papers citing papers by David Sinclair
This network shows the impact of papers produced by David Sinclair. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Sinclair. The network helps show where David Sinclair may publish in the future.
Co-authors
The 25 scholars most cited alongside David Sinclair, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.
All Works
Showing the 20 most-cited of 382 papers — load more, or switch the sort, to bring in the rest.
| # | Work | ||
|---|---|---|---|
| 1 | Therapeutic potential of resveratrol: the in vivo evidence Hit paper breakdown → | 2006 | 3154 |
| 2 | Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan Hit paper breakdown → | 2003 | 2984 |
| 3 | Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase Hit paper breakdown → | 2004 | 2730 |
| 4 | Mammalian Sirtuins: Biological Insights and Disease Relevance Hit paper breakdown → | 2010 | 1671 |
| 5 | Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase Hit paper breakdown → | 2004 | 1587 |
| 6 | Sirtuin activators mimic caloric restriction and delay ageing in metazoans Hit paper breakdown → | 2004 | 1430 |
| 7 | Sirtuins in mammals: insights into their biological function Hit paper breakdown → | 2007 | 1418 |
| 8 | Extrachromosomal rDNA Circles— A Cause of Aging in Yeast Hit paper breakdown → | 1997 | 1175 |
| 9 | Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging Hit paper breakdown → | 2013 | 1108 |
| 10 | The Intersection Between Aging and Cardiovascular Disease Hit paper breakdown → | 2012 | 1072 |
| 11 | SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis Hit paper breakdown → | 2007 | 863 |
| 12 | Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1 Hit paper breakdown → | 2002 | 832 |
| 13 | Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival Hit paper breakdown → | 2007 | 796 |
| 14 | The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice Hit paper breakdown → | 2014 | 692 |
| 15 | Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice Hit paper breakdown → | 2010 | 686 |
| 16 | Why does COVID-19 disproportionately affect older people? Hit paper breakdown → | 2020 | 683 |
| 17 | Molecular Biology of Aging Hit paper breakdown → | 1999 | 669 |
| 18 | SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging Hit paper breakdown → | 2008 | 649 |
| 19 | Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence Hit paper breakdown → | 2018 | 616 |
| 20 | Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds Hit paper breakdown → | 2016 | 615 |
About David Sinclair
David Sinclair is a scholar working on Molecular Biology, Geriatrics and Gerontology, Physiology, Aging and Epidemiology, having authored 382 papers that have together received 47.3k indexed citations. Recurring topics across this work include Sirtuins and Resveratrol in Medicine (102 papers), Genetics, Aging, and Longevity in Model Organisms (53 papers), Adipose Tissue and Metabolism (50 papers), Autophagy in Disease and Therapy (27 papers), Mitochondrial Function and Pathology (25 papers), Calcium signaling and nucleotide metabolism (19 papers), Biochemical effects in animals (16 papers) and DNA Repair Mechanisms (16 papers). The work is most often cited by research in Geriatrics and Gerontology (17.8k citations), Aging (6.4k citations), Physiology (3.8k citations), Physiology (13.5k citations) and Biological Psychiatry (934 citations). David Sinclair has collaborated with scholars based in United States, United Kingdom and Australia. Frequent co-authors include Joseph A. Baur, Leonard Guarente, Haim Cohen, Shaday Michán, Marcia C. Haigis, Kevin J. Bitterman, Konrad T. Howitz, Jason G. Wood, Brian J. North and Siva Lavu. Their work appears in journals such as Cochrane Database of Systematic Reviews, Journal of Clinical Pathology, Cell, Annals of Clinical Biochemistry International Journal of Laboratory Medicine and Cell Metabolism.
Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.