Leonard Guarente
Impact in
- Geriatrics and Gerontology top 0.01%
- Sirtuins and Resveratrol in Medicine
- Aging top 0.01%
- Genetics, Aging, and Longevity in Model Organisms
Papers in
-
- Sirtuins and Resveratrol in Medicine 97
- Aging 57
- Genetics, Aging, and Longevity in Model Organisms 57
- Co-authors
- Shin‐ichiro Imai (6 shared papers)David A. Sinclair (11 shared papers)Matt R. Kaeberlein (9 shared papers)Gil Blander (7 shared papers)Heidi A. Tissenbaum (3 shared papers)Hung-Chun Chang (3 shared papers)Christopher M. Armstrong (2 shared papers)Pierre‐Antoine Defossez (5 shared papers)
- Journals
- Cell (33 papers)Molecular and Cellular Biology (23 papers)Nature (12 papers)Proceedings of the National Academy of Sciences (12 papers)Journal of Biological Chemistry (8 papers)
- Partner nations
- United StatesCanadaJapan
In The Last Decade
Leonard Guarente
212 papers receiving 53.2k citations
Leonard Guarente's Hit Papers
Peers
Comparison fields: 5 of 180
- Geriatrics and Gerontology 20.4k
- Aging 8.8k
- Physiology 3.8k
- Physiology 15.7k
- Endocrine and Autonomic Systems 3.4k
Countries citing papers authored by Leonard Guarente
This map shows the geographic impact of Leonard Guarente's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leonard Guarente with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leonard Guarente more than expected).
Fields of papers citing papers by Leonard Guarente
This network shows the impact of papers produced by Leonard Guarente. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leonard Guarente. The network helps show where Leonard Guarente may publish in the future.
Co-authors
The 25 scholars most cited alongside Leonard Guarente, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.
All Works
Showing the 20 most-cited of 213 papers — load more, or switch the sort, to bring in the rest.
| # | Work | ||
|---|---|---|---|
| 1 | Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase Hit paper breakdown → | 2000 | 2978 |
| 2 | hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase Hit paper breakdown → | 2001 | 2316 |
| 3 | Negative Control of p53 by Sir2α Promotes Cell Survival under Stress Hit paper breakdown → | 2001 | 1866 |
| 4 | Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ Hit paper breakdown → | 2004 | 1714 |
| 5 | Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Hit paper breakdown → | 2001 | 1636 |
| 6 | Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia Hit paper breakdown → | 2011 | 1556 |
| 7 | Requirement of NAD and SIR2 for Life-Span Extension by Calorie Restriction in Saccharomyces cerevisiae Hit paper breakdown → | 2000 | 1543 |
| 8 | Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6 Hit paper breakdown → | 2006 | 1373 |
| 9 | The Sir2 Family of Protein Deacetylases Hit paper breakdown → | 2004 | 1320 |
| 10 | Extrachromosomal rDNA Circles— A Cause of Aging in Yeast Hit paper breakdown → | 1997 | 1222 |
| 11 | The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control Hit paper breakdown → | 2008 | 1211 |
| 12 | Mammalian SIRT1 Represses Forkhead Transcription Factors Hit paper breakdown → | 2004 | 1184 |
| 13 | Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation Hit paper breakdown → | 2007 | 1078 |
| 14 | The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling Hit paper breakdown → | 2013 | 1034 |
| 15 | SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells Hit paper breakdown → | 2006 | 998 |
| 16 | SIRT1 and other sirtuins in metabolism Hit paper breakdown → | 2014 | 985 |
| 17 | 2002 | 885 | |
| 18 | 2005 | 848 | |
| 19 | [12] High-efficiency transformation of yeast by electroporation Hit paper breakdown → | 1991 | 742 |
| 20 | 1999 | 709 |
About Leonard Guarente
Leonard Guarente is a scholar working on Geriatrics and Gerontology, Aging, Physiology, Molecular Biology and Epidemiology, having authored 213 papers that have together received 54.6k indexed citations. Recurring topics across this work include Sirtuins and Resveratrol in Medicine (97 papers), Genetics, Aging, and Longevity in Model Organisms (57 papers), Adipose Tissue and Metabolism (51 papers), Fungal and yeast genetics research (36 papers), Autophagy in Disease and Therapy (27 papers), Genomics and Chromatin Dynamics (19 papers), DNA Repair Mechanisms (18 papers) and Biochemical effects in animals (18 papers). The work is most often cited by research in Geriatrics and Gerontology (20.4k citations), Aging (8.8k citations), Physiology (3.8k citations), Physiology (15.7k citations) and Endocrine and Autonomic Systems (3.4k citations). Leonard Guarente has collaborated with scholars based in United States, Canada and Japan. Frequent co-authors include Shin‐ichiro Imai, David A. Sinclair, Matt R. Kaeberlein, Gil Blander, Heidi A. Tissenbaum, Hung-Chun Chang, Christopher M. Armstrong, Pierre‐Antoine Defossez, Su-Ju Lin and Frédéric Picard. Their work appears in journals such as Cell, Molecular and Cellular Biology, Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.
Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.