Leonard Guarente

71.2k citations
211 papers · 58.0k · 34 hit papers · h-index 108

Impact in

Papers in

Leonard Guarente

210 papers receiving 56.6k citations

Leonard Guarente's Hit Papers

Human trials exploring anti-aging medicines 2024 · 127 citations
1270+6+13Years since publication4008001.2k

Peers

Leonard Guarente
Comparison fields: 5 of 180
  • Geriatrics and Gerontology 22.2k
  • Aging 9.6k
  • Physiology 4.1k
  • Physiology 16.9k
  • Endocrine and Autonomic Systems 3.7k
Replace Rafael de Cabo with:
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Citations per year

Countries citing papers authored by Leonard Guarente

Since Specialization
Citations

This map shows the geographic impact of Leonard Guarente's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leonard Guarente with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leonard Guarente more than expected).

Fields of papers citing papers by Leonard Guarente

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leonard Guarente. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leonard Guarente. The network helps show where Leonard Guarente may publish in the future.

Co-authors

The 25 scholars most cited alongside Leonard Guarente, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Leonard Guarente Line = papers co-authored together Leonard Guarente links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 211 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
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20002972
2
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
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20012322
3
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
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20011875
4
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
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19991855
5
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
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20041703
6
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
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20011638
7
Requirement of NAD and SIR2 for Life-Span Extension by Calorie Restriction in Saccharomyces cerevisiae
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20001537
8
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
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20111476
9
The Sir2 Family of Protein Deacetylases
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20041315
10
Extrachromosomal rDNA Circles— A Cause of Aging in Yeast
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19971243
11
The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control
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20081197
12
Mammalian SIRT1 Represses Forkhead Transcription Factors
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20041190
13
Mammalian sirtuins—emerging roles in physiology, aging, and calorie restriction
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20061123
14
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
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20071059
15
The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
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2013982
16
SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells
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2006982
17
SIRT1 and other sirtuins in metabolism
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2014949
18
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
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2002891
19
Calorie restriction, SIRT1 and metabolism: understanding longevity
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2005854
20
[12] High-efficiency transformation of yeast by electroporation
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1991755

About Leonard Guarente

Leonard Guarente is a scholar working on Molecular Biology, Geriatrics and Gerontology, Physiology, Aging and Epidemiology, having authored 211 papers that have together received 58.0k indexed citations. Recurring topics across this work include Sirtuins and Resveratrol in Medicine (95 papers), Adipose Tissue and Metabolism (53 papers), Genetics, Aging, and Longevity in Model Organisms (53 papers), Fungal and yeast genetics research (39 papers), Autophagy in Disease and Therapy (28 papers), Genomics and Chromatin Dynamics (22 papers), DNA Repair Mechanisms (20 papers) and Biochemical effects in animals (19 papers). The work is most often cited by research in Geriatrics and Gerontology (22.2k citations), Aging (9.6k citations), Physiology (4.1k citations), Physiology (16.9k citations) and Endocrine and Autonomic Systems (3.7k citations). Leonard Guarente has collaborated with scholars based in United States, Canada and Japan. Frequent co-authors include Matt Kaeberlein, Shin‐ichiro Imai, David Sinclair, Gil Blander, Marcia C. Haigis, Heidi A. Tissenbaum, Christopher M. Armstrong, Su-Ju Lin, Hung-Chun Chang and Pierre‐Antoine Defossez. Their work appears in journals such as Cell, Molecular and Cellular Biology, Proceedings of the National Academy of Sciences, Genes & Development and Nature.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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