B. E. Leonard

6.7k citations

192 papers · 5.4k · 2 hit papers · h-index 35

Impact in

Biological Psychiatry top 0.1%
- Tryptophan and brain disorders
Behavioral Neuroscience top 0.2%
- Stress Responses and Cortisol

Papers in

Cellular and Molecular Neuroscience 85
- Neurotransmitter Receptor Influence on Behavior 52
- Neuroscience and Neuropharmacology Research 39
Molecular Biology 41
- Receptor Mechanisms and Signaling 20

Co-authors: John Kelly (25 shared papers)Cai Song (17 shared papers)Aileen S. Wrynn (1 shared paper)Christopher J. Earley (12 shared papers)Aye-Mu Myint (4 shared papers)Robert Verkerk (2 shared papers)Marta Kubera (2 shared papers)Michaël Maes (1 shared paper)
Journals: Human Psychopharmacology Clinical and Experimental (28 papers)Journal of Affective Disorders (11 papers)Pharmacology Biochemistry and Behavior (9 papers)Journal of Psychopharmacology (8 papers)Neuropharmacology (8 papers)
Partner nations: Ireland United Kingdom Netherlands

In The Last Decade

B. E. Leonard

185 papers receiving 5.1k citations

B. E. Leonard's Hit Papers

align trajectories log scale

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression 2010 · 567 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Progress in Neuro-Psychopharmacology and Biological Psychiatry
1997 Pharmacology & Therapeutics

Peers

Countries citing papers authored by B. E. Leonard

Since Specialization

Citations

This map shows the geographic impact of B. E. Leonard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by B. E. Leonard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites B. E. Leonard more than expected).

Fields of papers citing papers by B. E. Leonard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by B. E. Leonard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by B. E. Leonard. The network helps show where B. E. Leonard may publish in the future.

Co-authors

The 25 scholars most cited alongside B. E. Leonard, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with B. E. Leonard Line = papers co-authored together B. E. Leonard links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 192 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression Progress in Neuro-Psychopharmacology and Biological Psychiatry ·Michaël Maes, B. E. Leonard, Aye-Mu Myint, Marta Kubera, Robert Verkerk Hit paper breakdown →	2010	567
2	The olfactory bulbectomized rat as a model of depression: An update Pharmacology & Therapeutics ·John Kelly, Aileen S. Wrynn, B. E. Leonard Hit paper breakdown →	1997	556
3	The HPA and immune axes in stress: the involvement of the serotonergic system European Psychiatry ·B. E. Leonard	2005	246
4	Effects of psychotropic drugs on the behavior and neurochemistry of olfactory bulbectomized rats Pharmacology & Therapeutics ·Henk van Riezen, B. E. Leonard	1990	195
5	Anatomical, Physiological, and Behavioral Aspects of Olfactory Bulbectomy in The Rat International review of neurobiology ·B. E. Leonard, Michael P. Tuite	1981	176
6	Changes in immunoglobulin, complement and acute phase protein levels in the depressed patients and normal controls Journal of Affective Disorders ·Cai Song, Timothy G. Dinan, B. E. Leonard	1994	167
7	An assessment of the effects of central interleukin-1β, -2, -6, and tumor necrosis factor-α administration on some behavioural, neurochemical, endocrine and immune parameters in the rat Neuroscience ·Tim Connor, C. Song, B. E. Leonard, Z. Merali, H. Anisman	1998	160
8	Isolation and assay of noradrenaline, dopamine, 5-hydroxy-tryptamine, and several metabolites from brain tissue using disposable bio-rad columns packed with sephadex G-10 Journal of Pharmacological Methods ·Christopher J. Earley, B. E. Leonard	1978	139
9	Monoamine-related markers of depression: Changes following treatment Journal of Psychiatric Research ·David Healy, P.A. Carney, B. E. Leonard	1982	121
10	β-Amyloid(Phe(SO3H)24)25–35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation Behavioural Brain Research ·Tibor Harkany, Siobhain M. O’Mahony, John Kelly, Katalin Soós, Ivan Felizardo Contrera Toro, Botond Penke, Paul G.M. Luiten, Csaba Nyakas, Károly Gulya, B. E. Leonard	1998	89
11	Pharmacological Differences of Serotonin Reuptake Inhibitors and Possible Clinical Relevance Drugs ·B. E. Leonard	1992	87
12	Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naïve and medication-free schizophrenic patients Brain Behavior and Immunity ·Aye-Mu Myint, Markus Schwarz, Robert Verkerk, H.H. Mueller, J. Zach, Simon Scharpé, Harry W.M. Steinbusch, B. E. Leonard, Y.K. Kim	2011	86
13	The comparative pharmacology of new antidepressants. PubMed ·B. E. Leonard	1993	73
14	Ethyl-eicosapentaenoic acid ingestion prevents corticosterone-mediated memory impairment induced by central administration of interleukin-1β in rats Molecular Psychiatry ·Cai Song, Anthony G. Phillips, B. E. Leonard, David F. Horrobin	2003	70
15	Comparative effects of serotonergic agonists withvarying efficacy at the 5-HT_1Areceptor on core body temperature: modification by the selective 5-HT_1Areceptor antagonist WAY 100635 Journal of Psychopharmacology ·John F. Cryan, Padraig Kelliher, John Kelly, B. E. Leonard	1999	66
16	The Comparison of Changes in Behavior, Neurochemistry, Endocrine, and Immune Functions after Different Routes, Doses and Durations of Administrations of IL-1β in Rats Pharmacopsychiatry ·Cai Song, David F. Horrobin, B. E. Leonard	2006	62
17	GABA and gonadal hormones Brain Research ·Christopher J. Earley, B. E. Leonard	1978	60
18	Peripheral adrenoceptors and serotonin receptors in depression Journal of Affective Disorders ·David Healy, P.A. Carney, A. O'Halloran, B. E. Leonard	1985	60
19	Behavioral, Neurochemical, and Immunological Responses to CRF Administrationa Annals of the New York Academy of Sciences ·Cai Song, Bernadette Earley, B. E. Leonard	1995	59
20	The effect of testosterone and cyproterone acetate on the concentration of γ-aminobutyric acid in brain areas of aggressive and non-aggressive mice Pharmacology Biochemistry and Behavior ·Christopher J. Earley, B. E. Leonard	1977	58

About B. E. Leonard

B. E. Leonard is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology, Behavioral Neuroscience, Biological Psychiatry and Pharmacology, having authored 192 papers that have together received 5.4k indexed citations. Recurring topics across this work include Neurotransmitter Receptor Influence on Behavior (52 papers), Stress Responses and Cortisol (41 papers), Neuroscience and Neuropharmacology Research (39 papers), Tryptophan and brain disorders (34 papers), Neuroendocrine regulation and behavior (24 papers), Olfactory and Sensory Function Studies (21 papers), Receptor Mechanisms and Signaling (20 papers) and Treatment of Major Depression (20 papers). The work is most often cited by research in Biological Psychiatry (1.4k citations), Behavioral Neuroscience (1.4k citations), Sensory Systems (603 citations), Cellular and Molecular Neuroscience (1.9k citations) and Neurology (528 citations). B. E. Leonard has collaborated with scholars based in Ireland, United Kingdom and Netherlands. Frequent co-authors include John Kelly, Cai Song, Aileen S. Wrynn, Christopher J. Earley, Aye-Mu Myint, Robert Verkerk, Marta Kubera, Michaël Maes, Henk van Riezen and Michael P. Tuite. Their work appears in journals such as Human Psychopharmacology Clinical and Experimental, Journal of Affective Disorders, Pharmacology Biochemistry and Behavior, Journal of Psychopharmacology and Neuropharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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B. E. Leonard

B. E. Leonard's Hit Papers

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About B. E. Leonard

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