Stephen D. Schmidt

11.7k citations

38 papers · 7.4k · 3 hit papers · h-index 30

Impact in

Physiology top 0.1%
- Alzheimer's disease research and treatments
Neurology top 0.5%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in

Physiology 35
- Alzheimer's disease research and treatments 35
Cell Biology 13
- Cellular transport and secretion 10

Co-authors: Paul M. Mathews (34 shared papers)Ralph A. Nixon (29 shared papers)Ying Jiang (12 shared papers)Marc Mercken (8 shared papers)Peter St George‐Hyslop (11 shared papers)Anne M. Cataldo (6 shared papers)Rudolph E. Tanzi (3 shared papers)Corrinne M. Peterhoff (6 shared papers)
Journals: Journal of Biological Chemistry (5 papers)Neurobiology of Aging (4 papers)Proceedings of the National Academy of Sciences (4 papers)Journal of Neurochemistry (3 papers)Journal of Molecular Neuroscience (1 paper)
Partner nations: United States Canada Belgium

In The Last Decade

Stephen D. Schmidt

38 papers receiving 7.2k citations

Stephen D. Schmidt's Hit Papers

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Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease 2005 · 789 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2005 The Journal of Cell Biology
2000 Nature
1995 Science

Peers

Countries citing papers authored by Stephen D. Schmidt

Since Specialization

Citations

This map shows the geographic impact of Stephen D. Schmidt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen D. Schmidt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen D. Schmidt more than expected).

Fields of papers citing papers by Stephen D. Schmidt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen D. Schmidt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen D. Schmidt. The network helps show where Stephen D. Schmidt may publish in the future.

Co-authors

The 25 scholars most cited alongside Stephen D. Schmidt, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Stephen D. Schmidt Line = papers co-authored together Stephen D. Schmidt links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 38 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus Science ·Ephrat Levy‐Lahad, Wilma Wasco, Parvoneh Poorkaj, Donna Romano, Junko Oshima, Warren H. Pettingell, Chang-En Yu, P. D. Jondro, Stephen D. Schmidt, Kai Wang, Annette C. Crowley, Ying‐Hui Fu, Suzanne Y. Guénette, David J. Galas, Ellen Nemens, Ellen M. Wijsman, Thomas D. Bird, Gerard D. Schellenberg, Rudolph E. Tanzi Hit paper breakdown →	1995	1959
2	Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease Nature ·Christopher Janus, Jacqueline Pearson, JoAnne McLaurin, Paul M. Mathews, Ying Jiang, Stephen D. Schmidt, M. Azhar Chishti, Patrick Horne, Donna Heslin, Jacqueline A. French, Howard T.J. Mount, Ralph A. Nixon, Marc Mercken, Catherine Bergeron, Paul E. Fraser, Peter St George‐Hyslop, David Westaway Hit paper breakdown →	2000	1183
3	Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease The Journal of Cell Biology ·Wai Haung Yu, Ana María Cuervo, Asok Kumar, Corrinne M. Peterhoff, Stephen D. Schmidt, Ju‐Hyun Lee, Panaiyur S. Mohan, Marc Mercken, Mark R. Farmery, Lars O. Tjernberg, Ying Jiang, Karen Duff, Yasuo Uchiyama, Jan Näslund, Paul M. Mathews, Anne M. Cataldo, Ralph A. Nixon Hit paper breakdown →	2005	789
4	A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease Neurobiology of Disease ·Lorenzo M. Refolo, Miguel A. Pappolla, John J. LaFrancois, Brian Malester, Stephen D. Schmidt, Tara Thomas-Bryant, G S Tint, R. Wang, Marc Mercken, Suzana Petanceska, Karen Duff	2001	441
5	Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits Brain ·Dun-Sheng Yang, Philip Stavrides, Panaiyur S. Mohan, Susmita Kaushik, Asok Kumar, Masuo Ohno, Stephen D. Schmidt, Daniel W. Wesson, Urmi Bandyopadhyay, Ying Jiang, Monika Pawlik, Corrinne M. Peterhoff, Austin J. Yang, Donald A. Wilson, Peter St George‐Hyslop, David Westaway, Paul M. Mathews, Efrat Levy, Ana María Cuervo, Ralph A. Nixon	2010	353
6	Aβ is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis Nature Neuroscience ·Martin C. Herzig, David T. Winkler, Patrick Burgermeister, Michelle Pfeifer, Esther Kohler, Stephen D. Schmidt, Simone Danner, Dorothée Abramowski, Christine Stürchler-Pierrat, Kurt Bürki, Sjoerd G. van Duinen, Marion L. C. Maat–Schieman, Matthias Staufenbiel, Paul M. Mathews, Mathias Jucker	2004	319
7	Alzheimer’s-related endosome dysfunction in Down syndrome is Aβ-independent but requires APP and is reversed by BACE-1 inhibition Proceedings of the National Academy of Sciences ·Ying Jiang, Kerry Mullaney, Corrinne M. Peterhoff, Shaoli Che, Stephen D. Schmidt, Anne Boyer‐Boiteau, Stephen D. Ginsberg, Anne M. Cataldo, Paul M. Mathews, Ralph A. Nixon	2009	239
8	Rab5-stimulated Up-regulation of the Endocytic Pathway Increases Intracellular β-Cleaved Amyloid Precursor Protein Carboxyl-terminal Fragment Levels and Aβ Production Journal of Biological Chemistry ·Olivera M. Grbovic, Paul M. Mathews, Ying Jiang, Stephen D. Schmidt, Ravi Dinakar, Nicole B. Summers-Terio, Brian P. Ceresa, Ralph A. Nixon, Anne M. Cataldo	2003	195
9	Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease Journal of Clinical Investigation ·Fabrizio Trinchese, Mauro Fà, Shumin Liu, Hong Zhang, Ariel Hidalgo, Stephen D. Schmidt, Hisako Yamaguchi, Narihiko Yoshii, Paul M. Mathews, Ralph A. Nixon, Ottavio Arancio	2008	176
10	In vivo reduction of amyloid-β by a mutant copper transporter Proceedings of the National Academy of Sciences ·Amie L. Phinney, Bettina Drisaldi, Stephen D. Schmidt, Stan Lugowski, Veronica A. Coronado, Yan Liang, Patrick Horne, Jing Yang, Joannis Sekoulidis, Janaky Coomaraswamy, M. Azhar Chishti, Diane W. Cox, Paul M. Mathews, Ralph A. Nixon, George A. Carlson, Peter St George‐Hyslop, David Westaway	2003	175
11	Cystatin C inhibits amyloid-β deposition in Alzheimer's disease mouse models Nature Genetics ·Weiqian Mi, Monika Pawlik, Magdalena Sastre, Sonia S. Jung, David S Radvinsky, Andrew M Klein, John Sommer, Stephen D. Schmidt, Ralph A. Nixon, Paul M. Mathews, Efrat Levy	2007	166
12	Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins Journal of Biological Chemistry ·Dun-Sheng Yang, Anurag Tandon, Fusheng Chen, Gang Yu, Wai Haung Yu, Shigeki Arawaka, Hiroshi Hasegawa, Monika Duthie, Stephen D. Schmidt, T V Ramabhadran, Ralph A. Nixon, Paul M. Mathews, Sam Gandy, Howard T.J. Mount, Peter St George‐Hyslop, Paul E. Fraser	2002	140
13	Presenilin Mutations in Familial Alzheimer Disease and Transgenic Mouse Models Accelerate Neuronal Lysosomal Pathology Journal of Neuropathology & Experimental Neurology ·Anne M. Cataldo, Corrinne M. Peterhoff, Stephen D. Schmidt, Nicole B. Terio, Karen Duff, Margaret E. Beard, Paul M. Mathews, Ralph A. Nixon	2004	127
14	Binding of cystatin C to Alzheimer’s amyloid β inhibits in vitro amyloid fibril formation Neurobiology of Aging ·Magdalena Sastre, Miguel Calero, Monika Pawlik, Paul M. Mathews, Asok Kumar, Vlatko Danilov, Stephen D. Schmidt, Ralph A. Nixon, Blas Frangione, Efrat Levy	2004	125
15	A Synthetic Peptide Blocking the Apolipoprotein E/β-Amyloid Binding Mitigates β-Amyloid Toxicity and Fibril Formation in Vitro and Reduces β-Amyloid Plaques in Transgenic Mice American Journal Of Pathology ·Martin Sadowski, Joanna Pankiewicz, Henrieta Scholtzova, James A. Ripellino, Yongsheng Li, Stephen D. Schmidt, Paul M. Mathews, John Denis Fryer, David M. Holtzman, Einar M. Sigurdsson, Thomas Wısnıewskı	2004	124
16	Calpain Activity Regulates the Cell Surface Distribution of Amyloid Precursor Protein Journal of Biological Chemistry ·Paul M. Mathews, Ying Jiang, Stephen D. Schmidt, Olivera M. Grbovic, Marc Mercken, Ralph A. Nixon	2002	95
17	Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis Autophagy ·Dun‐Sheng Yang, Philip Stavrides, Panaiyur S. Mohan, Susmita Kaushik, Asok Kumar, Masuo Ohno, Stephen D. Schmidt, Daniel W. Wesson, Urmi Bandyopadhyay, Ying Jiang, Monika Pawlik, Corrinne M. Peterhoff, Austin J. Yang, Donald A. Wilson, Peter St George‐Hyslop, David Westaway, Paul M. Mathews, Efrat Levy, Ana María Cuervo, Ralph A. Nixon	2011	85
18	Alzheimer's Disease-related Overexpression of the Cation-dependent Mannose 6-Phosphate Receptor Increases Aβ Secretion Journal of Biological Chemistry ·Paul M. Mathews, Carolyn B. Guerra, Ying Jiang, Olivera M. Grbovic, Benjamin H. Kao, Stephen D. Schmidt, Ravi Dinakar, Marc Mercken, Annette Hille‐Rehfeld, Jack Rohrer, Pankaj Mehta, Anne M. Cataldo, Ralph A. Nixon	2002	83
19	ELISA Method for Measurement of Amyloid-β Levels Humana Press eBooks ·Stephen D. Schmidt, Ralph A. Nixon, Paul M. Mathews	2005	70
20	Dissociated phenotypes in presenilin transgenic mice define functionally distinct γ-secretases Proceedings of the National Academy of Sciences ·Peter Mastrangelo, Paul M. Mathews, M. Azhar Chishti, Stephen D. Schmidt, Yongjun Gu, Jing Yang, Matthew J. Mazzella, Janaky Coomaraswamy, Patrick Horne, Bob Strome, Heather Pelly, Georges Lévesque, Chris Ebeling, Ying Jiang, Ralph A. Nixon, Richard Rozmahel, Paul E. Fraser, Peter St George‐Hyslop, George A. Carlson, David Westaway	2005	64

About Stephen D. Schmidt

Stephen D. Schmidt is a scholar working on Physiology, Cell Biology, Molecular Biology, Computational Theory and Mathematics and Clinical Biochemistry, having authored 38 papers that have together received 7.4k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (35 papers), Cellular transport and secretion (10 papers), Computational Drug Discovery Methods (8 papers), Advanced Glycation End Products research (5 papers), Trace Elements in Health (5 papers), Cholinesterase and Neurodegenerative Diseases (4 papers), Nuclear Receptors and Signaling (3 papers) and Neuroinflammation and Neurodegeneration Mechanisms (3 papers). The work is most often cited by research in Physiology (5.6k citations), Neurology (1.1k citations), Biological Psychiatry (254 citations), Pharmacology (1.3k citations) and Cellular and Molecular Neuroscience (1.2k citations). Stephen D. Schmidt has collaborated with scholars based in United States, Canada and Belgium. Frequent co-authors include Paul M. Mathews, Ralph A. Nixon, Ying Jiang, Marc Mercken, Peter St George‐Hyslop, Anne M. Cataldo, Rudolph E. Tanzi, Corrinne M. Peterhoff, Wilma Wasco and Ellen M. Wijsman. Their work appears in journals such as Journal of Biological Chemistry, Neurobiology of Aging, Proceedings of the National Academy of Sciences, Journal of Neurochemistry and Journal of Molecular Neuroscience.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Stephen D. Schmidt

Stephen D. Schmidt's Hit Papers

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All Works

About Stephen D. Schmidt

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