David M. Holtzman
Impact in
- Neurology top 0.01%
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Biological Psychiatry top 0.01%
- Tryptophan and brain disorders
Papers in
- Physiology 341
- Alzheimer's disease research and treatments 321
- Co-authors
- Anne M. Fagan (137 shared papers)John C. Morris (122 shared papers)John R. Cirrito (55 shared papers)Kelly R. Bales (41 shared papers)Justin M. Long (7 shared papers)Steven M. Paul (37 shared papers)Ronald C. Petersen (4 shared papers)Erik S. Musiek (14 shared papers)
- Journals
- Alzheimer s & Dementia (44 papers)Journal of Neuroscience (43 papers)Annals of Neurology (27 papers)Neuron (25 papers)Proceedings of the National Academy of Sciences (24 papers)
- Partner nations
- United StatesGermanyJapan
In The Last Decade
David M. Holtzman
585 papers receiving 103.3k citations
David M. Holtzman's Hit Papers
Peers
Comparison fields: 5 of 205
- Neurology 21.4k
- Biological Psychiatry 5.1k
- Physiology 48.4k
- Psychiatry and Mental health 17.5k
- Developmental Neuroscience 3.4k
Countries citing papers authored by David M. Holtzman
This map shows the geographic impact of David M. Holtzman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David M. Holtzman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David M. Holtzman more than expected).
Fields of papers citing papers by David M. Holtzman
This network shows the impact of papers produced by David M. Holtzman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David M. Holtzman. The network helps show where David M. Holtzman may publish in the future.
Co-authors
The 25 scholars most cited alongside David M. Holtzman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.
All Works
Showing the 20 most-cited of 595 papers — load more, or switch the sort, to bring in the rest.
| # | Work | ||
|---|---|---|---|
| 1 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Hit paper breakdown → | 2011 | 7637 |
| 2 | The Diagnosis of Mild Cognitive Impairment due to Alzheimer’s Disease: Recommendations from the National Institute on Aging-Alzheimer’s Association Workgroups on Diagnostic Guidelines for Alzheimer’s Disease Hit paper breakdown → | 2013 | 2210 |
| 3 | Alzheimer Disease: An Update on Pathobiology and Treatment Strategies Hit paper breakdown → | 2019 | 2168 |
| 4 | Alzheimer disease Hit paper breakdown → | 2021 | 1596 |
| 5 | National Institute of Neurological Disorders and Stroke–Canadian Stroke Network Vascular Cognitive Impairment Harmonization Standards Hit paper breakdown → | 2006 | 1306 |
| 6 | TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model Hit paper breakdown → | 2015 | 1276 |
| 7 | The Role of Apolipoprotein E in Alzheimer's Disease Hit paper breakdown → | 2009 | 1263 |
| 8 | Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier Hit paper breakdown → | 2000 | 1224 |
| 9 | Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle Hit paper breakdown → | 2009 | 1223 |
| 10 | Alzheimer’s Disease: The Challenge of the Second Century Hit paper breakdown → | 2011 | 1170 |
| 11 | Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums Hit paper breakdown → | 2018 | 1141 |
| 12 | Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease Hit paper breakdown → | 2001 | 1115 |
| 13 | Apolipoprotein E controls cerebrovascular integrity via cyclophilin A Hit paper breakdown → | 2012 | 1042 |
| 14 | Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo Hit paper breakdown → | 2005 | 1031 |
| 15 | Hallmarks of neurodegenerative diseases Hit paper breakdown → | 2023 | 1016 |
| 16 | Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aβ 42 in humans Hit paper breakdown → | 2005 | 1001 |
| 17 | Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance Hit paper breakdown → | 2011 | 929 |
| 18 | TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease Hit paper breakdown → | 2017 | 873 |
| 19 | Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease Hit paper breakdown → | 2008 | 837 |
| 20 | Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model Hit paper breakdown → | 2002 | 770 |
About David M. Holtzman
David M. Holtzman is a scholar working on Physiology, Molecular Biology, Psychiatry and Mental health, Neurology and Cellular and Molecular Neuroscience, having authored 595 papers that have together received 105.5k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (321 papers), Dementia and Cognitive Impairment Research (110 papers), Neuroinflammation and Neurodegeneration Mechanisms (93 papers), Cholinesterase and Neurodegenerative Diseases (45 papers), Neuroscience and Neuropharmacology Research (39 papers), Computational Drug Discovery Methods (36 papers), Sleep and Wakefulness Research (33 papers) and Nuclear Receptors and Signaling (31 papers). The work is most often cited by research in Neurology (21.4k citations), Biological Psychiatry (5.1k citations), Physiology (48.4k citations), Psychiatry and Mental health (17.5k citations) and Developmental Neuroscience (3.4k citations). David M. Holtzman has collaborated with scholars based in United States, Germany and Japan. Frequent co-authors include Anne M. Fagan, John C. Morris, John R. Cirrito, Kelly R. Bales, Justin M. Long, Steven M. Paul, Ronald C. Petersen, Erik S. Musiek, Steven T. DeKosky and Alison Goate. Their work appears in journals such as Alzheimer s & Dementia, Journal of Neuroscience, Annals of Neurology, Neuron and Proceedings of the National Academy of Sciences.
Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.