Markus G. Grütter

14.7k citations

172 papers · 12.5k · 1 hit paper · h-index 61

Impact in

Virology top 1%
- HIV Research and Treatment
Molecular Biology top 0.5%
- Protein Structure and Dynamics
- Cell death mechanisms and regulation
- Inflammasome and immune disorders

Papers in

Molecular Biology 104
- Protein Structure and Dynamics 37
- Cell death mechanisms and regulation 23
- Inflammasome and immune disorders 9
- Biochemical and Structural Characterization 9
Materials Chemistry 66
- Enzyme Structure and Function 64

Co-authors: Christophe Briand (21 shared papers)Peer R. E. Mittl (29 shared papers)Guido Capitani (30 shared papers)Andreas Plückthun (16 shared papers)Michael P. Schlunegger (5 shared papers)A. Kohl (9 shared papers)Patrick Amstutz (5 shared papers)Patrik Forrer (4 shared papers)
Journals: Journal of Molecular Biology (23 papers)Structure (15 papers)Journal of Biological Chemistry (10 papers)FEBS Letters (9 papers)Proceedings of the National Academy of Sciences (9 papers)
Partner nations: Switzerland United States Germany

In The Last Decade

Markus G. Grütter

172 papers receiving 12k citations

Markus G. Grütter's Hit Papers

align trajectories log scale

TRIM5 is an innate immune sensor for the retrovirus capsid lattice 2011 · 546 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2011 Nature

Peers

Countries citing papers authored by Markus G. Grütter

Since Specialization

Citations

This map shows the geographic impact of Markus G. Grütter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Markus G. Grütter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Markus G. Grütter more than expected).

Fields of papers citing papers by Markus G. Grütter

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Markus G. Grütter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Markus G. Grütter. The network helps show where Markus G. Grütter may publish in the future.

Co-authors

The 25 scholars most cited alongside Markus G. Grütter, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Markus G. Grütter Line = papers co-authored together Markus G. Grütter links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 172 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	High-affinity binders selected from designed ankyrin repeat protein libraries Nature Biotechnology ·Patrick Amstutz, A. Kohl, Michael T. Stumpp, Christophe Briand, Patrik Forrer, Markus G. Grütter, Andreas Plückthun +1 other	2004	557
2	TRIM5 is an innate immune sensor for the retrovirus capsid lattice Nature ·Thomas Pertel, Stéphane Hausmann, Damien Morger, Sara Züger, Jessica Guerra, Josefina Lascano, Christian Reinhard, Federico Andrea Santoni Hit paper breakdown →	2011	546
3	Caspases: key players in programmed cell death Current Opinion in Structural Biology ·Markus G. Grütter	2000	427
4	Structure-based design of aliskiren, a novel orally effective renin inhibitor Biochemical and Biophysical Research Communications ·Jeanette Marjorie Wood, Jürgen Maibaum, Joseph Rahuel, Markus G. Grütter, Nissim-Claude Cohen, Vittorio Rasetti, H. Rüeger, Richard Göschke	2003	418
5	The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex Journal of Biological Chemistry ·Olivier Micheau, Margot Thome, Pascal Schneider, Nils Holler, Jürg Tschopp, Donald W. Nicholson, Christophe Briand, Markus G. Grütter	2002	405
6	Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors PLoS Biology ·Gaby Sennhauser, Patrick Amstutz, Christophe Briand, Otso Storchenegger, Markus G. Grütter	2006	290
7	Precision is essential for efficient catalysis in an evolved Kemp eliminase Nature ·Rebecca Blomberg, Hajo Kries, Daniel M. Pinkas, Peer R. E. Mittl, Markus G. Grütter, Heidi K. Privett, Stephen L. Mayo, Donald Hilvert	2013	287
8	An unusual feature revealed by the crystal structure at 2.2 Å resolution of human transforming growth fact or-β2 Nature ·Michael P. Schlunegger, Markus G. Grütter	1992	286
9	Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop Proceedings of the National Academy of Sciences ·Thomas Eicher, Hi-jea Cha, Markus A. Seeger, Lorenz Brandstätter, Jasmin El-Delik, Jürgen A. Bohnert, Winfried V. Kern, François Verrey	2012	278
10	The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing Cell Death and Differentiation ·Stéphanie Papin, Solange Cuenin, Laetitia Agostini, Fabio Martinon, Sabine Werner, Hans‐Dietmar Beer, Christian Grütter, Markus G. Grütter	2007	267
11	Insights into the Regulatory Mechanism for Caspase-8 Activation Molecular Cell ·Mrudula Donepudi, A. Mac Sweeney, Christophe Briand, Markus G. Grütter	2003	240
12	Designed to be stable: Crystal structure of a consensus ankyrin repeat protein Proceedings of the National Academy of Sciences ·A. Kohl, Patrik Forrer, Michael Tobias Stumpp, Andreas Plückthun, Markus G. Grütter +1 other	2003	236
13	Three-Dimensional Structure of the Adenovirus Major Coat Protein Hexon Science ·Michael M. Roberts, Janice L. White, Markus G. Grütter, Roger M. Burnett	1986	218
14	Structure of Recombinant Human CPP32 in Complex with the Tetrapeptide Acetyl-Asp-Val-Ala-Asp Fluoromethyl Ketone Journal of Biological Chemistry ·Peer R. E. Mittl, Stefania Di Marco, Joseph Krebs, Xu Bai, Donald S. Karanewsky, John P. Priestle, K J Tomaselli, Markus G. Grütter	1997	216
15	Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation Nature Structural & Molecular Biology ·Christophe Briand, Markus G. Grütter, Markus A. Seeger +1 other	2012	213
16	NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22 Journal of Clinical Investigation ·Marianne Rebecca Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Stephan R. Vavricka, Sylvie Scharl, Petrus M. Gutte	2016	213
17	Molecular basis of thermostability in the lysozyme from bacteriophage T4 Nature ·Markus G. Grütter, Richard B. Hawkes, Brian W. Matthews	1979	200
18	Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa Journal of Molecular Biology ·Gaby Sennhauser, Magdalena A. Bukowska, Christophe Briand, Markus G. Grütter	2009	197
19	Structural basis for specificity of GRB2-SH2 revealed by a novel ligand binding mode Nature Structural Biology ·Joseph Rahuel, Brigitte Gay, Dirk Erdmann, André Strauss, Carlos Garcı́a-Echeverrı́a, Pascal Furet, Giorgio Caravatti, Heinz Fretz	1996	196
20	The 2.5 A X‐ray crystal structure of the acid‐stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha‐chymotrypsin. The EMBO Journal ·Markus G. Grütter, Gabrielle Fendrich, Robert Huber, Wolfram Bode	1988	193

About Markus G. Grütter

Markus G. Grütter is a scholar working on Molecular Biology, Materials Chemistry, Cancer Research, Oncology and Virology, having authored 172 papers that have together received 12.5k indexed citations. Recurring topics across this work include Enzyme Structure and Function (64 papers), Protein Structure and Dynamics (37 papers), Cell death mechanisms and regulation (23 papers), Protease and Inhibitor Mechanisms (10 papers), Drug Transport and Resistance Mechanisms (9 papers), Inflammasome and immune disorders (9 papers), Biochemical and Structural Characterization (9 papers) and interferon and immune responses (8 papers). The work is most often cited by research in Virology (579 citations), Molecular Biology (6.6k citations), Molecular Medicine (637 citations), Structural Biology (115 citations) and Oncology (998 citations). Markus G. Grütter has collaborated with scholars based in Switzerland, United States and Germany. Frequent co-authors include Christophe Briand, Peer R. E. Mittl, Guido Capitani, Andreas Plückthun, Michael P. Schlunegger, A. Kohl, Patrick Amstutz, Patrik Forrer, Brian W. Matthews and Richard B. Hawkes. Their work appears in journals such as Journal of Molecular Biology, Structure, Journal of Biological Chemistry, FEBS Letters and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Markus G. Grütter

Impact in

Papers in i

In The Last Decade

Markus G. Grütter

Markus G. Grütter's Hit Papers

Peers

Countries citing papers authored by Markus G. Grütter

Fields of papers citing papers by Markus G. Grütter

All Works

About Markus G. Grütter

Explore authors with similar magnitude of impact

Papers in