Rajeev S. Bhide

1.3k citations

19 papers · 495 · h-index 13

Impact in

Organic Chemistry top 10%
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Click Chemistry and Applications
- Synthesis and Biological Evaluation
- Synthesis and Reactivity of Heterocycles
Pharmaceutical Science

Papers in

Molecular Biology 13
- Angiogenesis and VEGF in Cancer 6
- PI3K/AKT/mTOR signaling in cancer 3
- Enzyme Catalysis and Immobilization 2
- Retinoids in leukemia and cellular processes 2
- Fibroblast Growth Factor Research 2
Organic Chemistry 8

Co-authors: Joseph Fargnoli (8 shared papers)John T. Hunt (8 shared papers)Barri Wautlet (7 shared papers)R. M. Borzilleri (6 shared papers)Amrita V. Kamath (5 shared papers)Steven Mortillo (4 shared papers)Louis J. Lombardo (7 shared papers)Robert Jeyaseelan (5 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Journal of Medicinal Chemistry (3 papers)Tetrahedron Letters (2 papers)Drug Metabolism and Disposition (1 paper)Molecular Cancer Therapeutics (1 paper)
Partner nations: United States Germany Sweden

In The Last Decade

Rajeev S. Bhide

19 papers receiving 473 citations

Peers

Countries citing papers authored by Rajeev S. Bhide

Since Specialization

Citations

This map shows the geographic impact of Rajeev S. Bhide's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rajeev S. Bhide with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rajeev S. Bhide more than expected).

Fields of papers citing papers by Rajeev S. Bhide

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rajeev S. Bhide. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rajeev S. Bhide. The network helps show where Rajeev S. Bhide may publish in the future.

Co-authors

The 25 scholars most cited alongside Rajeev S. Bhide, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Rajeev S. Bhide Line = papers co-authored together Rajeev S. Bhide links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Discovery of the Pyrrolo[2,1-f][1,2,4]triazine Nucleus as a New Kinase Inhibitor Template Journal of Medicinal Chemistry ·John T. Hunt, Toomas Mitt, R. M. Borzilleri, Johnni Gullo-Brown, Joseph Fargnoli, Brian E. Fink, Wen-Ching Han, Steven Mortillo, Gregory D. Vite, Barri Wautlet, Tai‐Tong Wong, Chiang Yu, Xiaoping Zheng, Rajeev S. Bhide	2004	82
2	Design, Synthesis, and Evaluation of Orally Active 4-(2,4-Difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Inhibitors Journal of Medicinal Chemistry ·R. M. Borzilleri, Xiaoping Zheng, Ligang Qian, Christopher D. Ellis, Zhen‐Wei Cai, Barri Wautlet, Steve Mortillo, Robert Jeyaseelan, Daniel Kukral, Aberra Fura, Amrita V. Kamath, Viral Vyas, John S. Tokarski, Joel C. Barrish, John T. Hunt, Louis J. Lombardo, Joseph Fargnoli, Rajeev S. Bhide	2005	55
3	The Antiangiogenic Activity in Xenograft Models of Brivanib, a Dual Inhibitor of Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Kinases Molecular Cancer Therapeutics ·Rajeev S. Bhide, Louis J. Lombardo, John T. Hunt, Zhen‐Wei Cai, Joel C. Barrish, Susan Galbraith, Robert Jeyaseelan, Steven Mortillo, Barri Wautlet, Bala Krishnan, Daniel Kukral, Harold Malone, Anne Lewin, Benjamin J. Henley, Joseph Fargnoli	2010	54
4	Discovery and Evaluation of N-Cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide (BMS-605541), a Selective and Orally Efficacious Inhibitor of Vascular Endothelial Growth Factor Receptor-2 Journal of Medicinal Chemistry ·R. M. Borzilleri, Rajeev S. Bhide, Joel C. Barrish, Celia D’Arienzo, George Derbin, Joseph Fargnoli, John T. Hunt, Robert Jeyaseelan, Amrita V. Kamath, Daniel Kukral, Punit Marathe, Steve Mortillo, Ligang Qian, John S. Tokarski, Barri Wautlet, Xiaoping Zheng, Louis J. Lombardo	2006	39
5	Concise and Efficient Synthesis of 4-Fluoro-1H-pyrrolo[2,3-b]pyridine Organic Letters ·Carl Thibault, Alexandre L’Heureux, Rajeev S. Bhide, Réjean Ruel	2003	37
6	Preclinical pharmacokinetics and in vitro metabolism of brivanib (BMS-540215), a potent VEGFR2 inhibitor and its alanine ester prodrug brivanib alaninate Cancer Chemotherapy and Pharmacology ·Punit H. Marathe, Amrita V. Kamath, Yueping Zhang, Celia D’Arienzo, Rajeev S. Bhide, Joseph Fargnoli	2009	35
7	Rational design of potent carboxylic acid based bisubstrate inhibitors of ras farnesyl protein transferase Bioorganic & Medicinal Chemistry Letters ·Rajeev S. Bhide, Dinesh V. Patel, Manorama M. Patel, Simon P. Robinson, Lisa Hunihan, Eric M. Gordon	1994	31
8	Synthesis and SAR of 4-(3-hydroxyphenylamino)pyrrolo[2,1-f][1,2,4]triazine based VEGFR-2 kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·R. M. Borzilleri, Zhen‐Wei Cai, Christopher D. Ellis, Joseph Fargnoli, Aberra Fura, Tracy Gerhardt, Bindu Goyal, John T. Hunt, Steven Mortillo, Ligang Qian, John S. Tokarski, Viral Vyas, Barri Wautlet, Xioping Zheng, Rajeev S. Bhide	2005	28
9	A chiral bicyclic intermediate for the synthesis of forskolin Tetrahedron Letters ·Guido Bold, Shouchung Chao, Rajeev S. Bhide, Shih‐Hsiung Wu, Dinesh V. Patel, Charles J. Sih, Connie G. Chidester	1987	26
10	Synthesis, SAR, and Evaluation of 4-[2,4-Difluoro-5-(cyclopropylcarbamoyl)phenylamino]pyrrolo[2,1-f][1,2,4]triazine-based VEGFR-2 kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Zhen‐Wei Cai, Donna Wei, R. M. Borzilleri, Ligang Qian, Amrita V. Kamath, Steven Mortillo, Barri Wautlet, Benjamin J. Henley, Robert Jeyaseelan, John S. Tokarski, John T. Hunt, Rajeev S. Bhide, Joseph Fargnoli, Louis J. Lombardo	2008	22
11	Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors Bioorganic & Medicinal Chemistry Letters ·Rajeev S. Bhide, Alec E. Keon, Carolyn A. Weigelt, John S. Sack, Robert J. Schmidt, Shuqun Lin, Hai‐Yun Xiao, Steven H. Spergel, James Kempson, William J. Pitts, Julie Carman, Michael A. Poss	2017	17
12	Dasatinib (BMS-354825) Overcomes Multiple Mechanisms of Imatinib Resistance in Chronic Myeloid Leukemia (CML). Blood ·Francis Y. Lee, Mei-Li Wen, Rajeev S. Bhide, Amy Camuso, Stephen Castenada, Krista Fager, Christine Flefleh, Ivan Inigo, David Kan, Roger Luo, Kelly McGlinchey, Richard Smykla, Robert A. Wild, R. M. Borzilleri, Louis J. Lombardo	2005	15
13	Di-tert-butylmethylsilyl (DTBMS) trifluoromethanesulfonate. Preparation and synthetic applications of DTBMS esters and enol ethers Tetrahedron Letters ·Rajeev S. Bhide, Bruce S. Levison, Ram B. Sharma, Subrata Ghosh, Robert G. Salomon	1986	13
14	Discovery and SAR of pyrrolo[2,1-f][1,2,4]triazin-4-amines as potent and selective PI3Kδ inhibitors Bioorganic & Medicinal Chemistry Letters ·Rajeev S. Bhide, James Neels, Lan-Ying Qin, Zheming Ruan, Sylwia Stachura, Carolyn A. Weigelt, John S. Sack, Kevin Stefanski, Xiaomei Gu, Jenny Xie, Christine B. Goldstine, Stacey Skala, Donna L. Pedicord, Stefan Ruepp, T. G. Murali Dhar, Percy H. Carter, Luisa Salter–Cid, Michael A. Poss, Paul Davies	2016	12
15	Identification of highly potent and selective PI3Kδ inhibitors Bioorganic & Medicinal Chemistry Letters ·David Marcoux, Lan-Ying Qin, Zheming Ruan, Qing Shi, Qian Ruan, Carolyn A. Weigelt, Hongchen Qiu, Gary L. Schieven, John Hynes, Rajeev S. Bhide, Michael A. Poss, Joseph A. Tino	2017	8
16	PBr₃-DMF Assisted Elimination of a Highly Hindered Diallylic Tertiary Alcohol in a Bicyclic System: Synthesis of a Key Intermediate Useful for the Total Synthesis of Forskolin Synthetic Communications ·Satyanarayana Nampalli, Rajeev S. Bhide, Hisao Nakai	1992	8
17	Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibitor complex Bioorganic & Medicinal Chemistry Letters ·Soong‐Hoon Kim, Keith L. Constantine, Gerald J. Duke, Valentina Goldfarb, John T. Hunt, Stephen R. Johnson, Kevin Kish, Herbert E. Klei, Patricia A. McDonnell, William J. Metzler, Luciano Mueller, Michael A. Poss, Craig R. Fairchild, Rajeev S. Bhide	2013	6
18	Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b ]pyridin-5-yl)pyrrolo[2,1-f ][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey Drug Metabolism and Disposition ·Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna Wei, Louis J. Lombardo, Yue‐Zhong Shu	2008	5
19	Preclinical studies of BMS-582664, an alanine prodrug of BMS-540215, a potent, dual inhibitor of VEGFR-2 and FGFR-1 kinases Joseph Fargnoli, Rajeev S. Bhide, Louis J. Lombardo, John T. Hunt, Zhen‐Wei Cai, Joel C. Barrish, Susan Galbraith, Robert Jeyaseelan, Steve Mortillo, Dan Kukral, Barri Wautlet, Bala Krishnan, Anne Lewin, Benjamin J. Henley	2005	2

About Rajeev S. Bhide

Rajeev S. Bhide is a scholar working on Molecular Biology, Organic Chemistry, Oncology, Cancer Research and Genetics, having authored 19 papers that have together received 495 indexed citations. Recurring topics across this work include Angiogenesis and VEGF in Cancer (6 papers), Cancer, Hypoxia, and Metabolism (4 papers), HER2/EGFR in Cancer Research (3 papers), Chronic Lymphocytic Leukemia Research (3 papers), PI3K/AKT/mTOR signaling in cancer (3 papers), Enzyme Catalysis and Immobilization (2 papers), Retinoids in leukemia and cellular processes (2 papers) and Fibroblast Growth Factor Research (2 papers). The work is most often cited by research in Organic Chemistry (250 citations), Pharmaceutical Science (27 citations), Oncology (96 citations), Genetics (32 citations) and Molecular Biology (221 citations). Rajeev S. Bhide has collaborated with scholars based in United States, Germany and Sweden. Frequent co-authors include Joseph Fargnoli, John T. Hunt, Barri Wautlet, R. M. Borzilleri, Amrita V. Kamath, Steven Mortillo, Louis J. Lombardo, Robert Jeyaseelan, Xiaoping Zheng and Zhen‐Wei Cai. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Tetrahedron Letters, Drug Metabolism and Disposition and Molecular Cancer Therapeutics.

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