Kevin Kish

3.0k citations

38 papers · 2.0k · 1 hit paper · h-index 20

Impact in

Hematology top 2%
- Chronic Myeloid Leukemia Treatments
Genetics top 5%
- Chronic Lymphocytic Leukemia Research
- Estrogen and related hormone effects

Papers in

Molecular Biology 28
- Melanoma and MAPK Pathways 8
- Wnt/β-catenin signaling in development and cancer 5
- Biochemical and Molecular Research 5
Organic Chemistry 11
- Synthesis and biological activity 4

Co-authors: Susan E. Kiefer (12 shared papers)Herbert E. Klei (13 shared papers)Dianlin Xie (6 shared papers)John S. Sack (12 shared papers)Yaqun Zhang (5 shared papers)John A. Newitt (8 shared papers)John S. Tokarski (4 shared papers)Michael Wittekind (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (17 papers)Journal of Medicinal Chemistry (8 papers)ACS Medicinal Chemistry Letters (1 paper)Endocrinology (1 paper)The Journal of Strength and Conditioning Research (1 paper)
Partner nations: United States Germany Japan

In The Last Decade

Kevin Kish

38 papers receiving 1.9k citations

Kevin Kish's Hit Papers

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The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants 2006 · 522 citations

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Countries citing papers authored by Kevin Kish

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Citations

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Fields of papers citing papers by Kevin Kish

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kevin Kish. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kevin Kish. The network helps show where Kevin Kish may publish in the future.

Co-authors

The 25 scholars most cited alongside Kevin Kish, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kevin Kish Line = papers co-authored together Kevin Kish links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 38 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants Cancer Research ·John S. Tokarski, John A. Newitt, Chieh Ying J. Chang, Janet Cheng, Michael Wittekind, Susan E. Kiefer, Kevin Kish, Francis Y. F. Lee, Robert Borzillerri, Louis J. Lombardo, Dianlin Xie, Yaqun Zhang, Herbert E. Klei Hit paper breakdown →	2006	522
2	Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone Proceedings of the National Academy of Sciences ·John S. Sack, Kevin Kish, Chihuei Wang, Ricardo M. Attar, Susan E. Kiefer, Yongmi An, Ginger Wu, Julie E. Scheffler, Mark Salvati, Stanley R. Krystek, Roberto Weinmann, Howard Einspahr	2001	357
3	Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP) Bioorganic & Medicinal Chemistry Letters ·Richard Sulsky, David R. Magnin, Yanting Huang, Ligaya M. Simpkins, Prakash C. Taunk, Manorama M. Patel, Yeheng Zhu, Terry R. Stouch, Donna Bassolino‐Klimas, Rex A. Parker, Thomas Harrity, Robert H. Stoffel, David S. Taylor, Thomas Lavoie, Kevin Kish, Bruce L. Jacobson, S. Sheriff, Leonard P. Adam, William R. Ewing, Jeffrey A. Robl	2006	126
4	Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation Protein Science ·William J. Metzler, Joseph Yanchunas, Carolyn A. Weigelt, Kevin Kish, Herbert E. Klei, Dianlin Xie, Yaqun Zhang, Martin J. Corbett, James Tamura, Bin He, Lawrence G. Hamann, Mark Kirby, Jovita Marcinkeviciene	2008	103
5	Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core Bioorganic & Medicinal Chemistry Letters ·Prasanna Sivaprakasam, Xiaojun Han, Rita L. Civiello, Swanee Jacutin-Porte, Kevin Kish, Matt Pokross, H.A. Lewis, Nazia Ahmed, Nicolas Szapiel, John A. Newitt, Eric T. Baldwin, Hong Xiao, Carol Krause, Hyunsoo Park, Michelle Nophsker, Jonathan Lippy, Catherine R. Burton, David R. Langley, John E. Macor, Gene M. Dubowchik	2015	100
6	Pharmacological and X-Ray Structural Characterization of a Novel Selective Androgen Receptor Modulator: Potent Hyperanabolic Stimulation of Skeletal Muscle with Hypostimulation of Prostate in Rats Endocrinology ·Jacek Ostrowski, Joyce E. Kuhns, John A. Lupisella, Mark C. Manfredi, Blake C. Beehler, Stanley R. Krystek, Yingzhi Bi, Chong‐Qing Sun, Ramakrishna Seethala, Rajasree Golla, Paul G. Sleph, Aberra Fura, Yongmi An, Kevin Kish, John S. Sack, Kasim A. Mookhtiar, Gary J. Grover, Lawrence G. Hamann	2006	99
7	Structural basis for CARM1 inhibition by indole and pyrazole inhibitors Biochemical Journal ·John S. Sack, Sandrine Thieffine, Tiziano Bandiera, Marina Fasolini, Gerald J. Duke, Lata Jayaraman, Kevin Kish, Herbert E. Klei, Ashok V. Purandare, Pamela Rosettani, Sonia Troiani, Dianlin Xie, J. A. Bertrand	2011	75
8	Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors Journal of Medicinal Chemistry ·Guanglin Luo, Ling Chen, Catherine R. Burton, Hong Xiao, Prasanna Sivaprakasam, Carol Krause, Yang Cao, Nengyin Liu, Jonathan Lippy, Wendy Clarke, Kimberly J. Snow, Joseph Raybon, Vinod Arora, Matt Pokross, Kevin Kish, H.A. Lewis, David R. Langley, John E. Macor, Gene M. Dubowchik	2016	56
9	Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Mark Salvati, Aaron Balog, Weifang Shan, Donna Wei, Dacia Pickering, Ricardo M. Attar, Jieping Geng, Cheryl A. Rizzo, Marco M. Gottardis, Roberto Weinmann, Stanley R. Krystek, John S. Sack, Yongmi An, Kevin Kish	2004	48
10	Benzothiazole based inhibitors of p38α MAP kinase Bioorganic & Medicinal Chemistry Letters ·Chunjian Liu, James C. Lin, Sidney Pitt, Rosemary F. Zhang, John S. Sack, Susan E. Kiefer, Kevin Kish, Arthur M. Doweyko, Hongjian Zhang, Punit H. Marathe, James M. Trzăskos, Murray McKinnon, John H. Dodd, Joel C. Barrish, Gary L. Schieven, Katerina Leftheris	2008	47
11	Discovery of 6-(Aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as Potent, Selective Dipeptidyl Peptidase-4 (DPP4) Inhibitors Journal of Medicinal Chemistry ·Wei Meng, Robert Brigance, Hannguang J. Chao, Aberra Fura, Thomas Harrity, Jovita Marcinkeviciene, Stephen P. O’Connor, James Tamura, Dianlin Xie, Yaqun Zhang, Herbert E. Klei, Kevin Kish, Carolyn A. Weigelt, Huji Turdi, Aiying Wang, Robert Zahler, Mark Kirby, Lawrence G. Hamann	2010	41
12	Pyrazolo-pyrimidines: A novel heterocyclic scaffold for potent and selective p38α inhibitors Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das, Robert V. Moquin, Sidney Pitt, Rosemary Zhang, Ding Ren Shen, Kim W. McIntyre, Kathleen M. Gillooly, Arthur M. Doweyko, John S. Sack, Hongjian Zhang, Susan E. Kiefer, Kevin Kish, Murray McKinnon, Joel C. Barrish, John H. Dodd, Gary L. Schieven, Katerina Leftheris	2008	37
13	Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage ACS Medicinal Chemistry Letters ·Amy C. Hart, Lynn M. Abell, Junqing Guo, Michael Mertzman, Ramesh Padmanabha, John E. Macor, Charu Chaudhry, Hao Lu, K O'Malley, Patrick J. Shaw, Carolyn A. Weigelt, Matthew Pokross, Kevin Kish, Kyoung S. Kim, Lyndon A. M. Cornelius, Andrew Douglas, Deepa Calambur, Ping Zhang, Brian Carpenter, William J. Pitts	2019	31
14	Design, Structure−Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors Journal of Medicinal Chemistry ·Yan Shi, Doree Sitkoff, Jing Zhang, Herbert E. Klei, Kevin Kish, Eddie C.‐K. Liu, Karen S. Hartl, Steve M. Seiler, Ming Chang, Christine Huang, Sonia Youssef, Thomas E. Steinbacher, William A. Schumacher, Nyeemah Grazier, Andrew T. Pudzianowski, Atsu Apedo, Lorell Discenza, Joseph Yanchunas, Philip D. Stein, Karnail S. Atwal	2008	27
15	Utilization of a nitrogen–sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38α MAP kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Shuqun Lin, Stephen T. Wrobleski, John Hynes, Sidney Pitt, Rosemary Zhang, Yi Fan, Arthur M. Doweyko, Kevin Kish, John S. Sack, Mary F. Malley, Susan E. Kiefer, John A. Newitt, Murray McKinnon, James M. Trzăskos, Joel C. Barrish, John H. Dodd, Gary L. Schieven, Katerina Leftheris	2010	26
16	Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38α MAP kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Stephen T. Wrobleski, Shuqun Lin, John Hynes, Hong Wu, Sidney Pitt, Ding Ren Shen, Rosemary Zhang, Kathleen M. Gillooly, David J. Shuster, Kim W. McIntyre, Arthur M. Doweyko, Kevin Kish, Jeffrey Tredup, Gerald J. Duke, John S. Sack, Murray McKinnon, John H. Dodd, Joel C. Barrish, Gary L. Schieven, Katerina Leftheris	2008	25
17	The Crystal Structure of Abl Kinase with BMS-354825, a Dual SRC/ABL Kinase Inhibitor. Blood ·John S. Tokarski, John A. Newitt, Francis Y. Lee, Louis J. Lombardo, R. M. Borzilleri, Kevin Kish, Dianlin Xie, Yaqun Zhang, Janet Cheng, Susan E. Kiefer, Chieh Ying J. Chang, Herbert E. Klei	2004	21
18	X-Ray Crystal Structures of Human Immunodeficiency Virus Type 1 Protease Mutants Complexed with Atazanavir Journal of Virology ·Herbert E. Klei, Kevin Kish, Pin-Fang Lin, Qi Guo, Jacques Friborg, Ronald E. Rose, Yaqun Zhang, Valentina Goldfarb, David R. Langley, Michael Wittekind, S. Sheriff	2007	21
19	Aroylguanidine-based factor Xa inhibitors: The discovery of BMS-344577 Bioorganic & Medicinal Chemistry Letters ·Yan Shi, Chi Li, Stephen P. O’Connor, Jing Zhang, Mengxiao Shi, Sharon N. Bisaha, Ying Wang, Doree Sitkoff, Andrew T. Pudzianowski, Christine Huang, Herbert E. Klei, Kevin Kish, Joseph Yanchunas, Eddie C.‐K. Liu, Karen S. Hartl, Steve M. Seiler, Thomas E. Steinbacher, William A. Schumacher, Karnail S. Atwal, Philip D. Stein	2009	19
20	5-Amino-pyrazoles as potent and selective p38α inhibitors Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das, Robert V. Moquin, Alaric J. Dyckman, Tianle Li, Sidney Pitt, Rosemary Zhang, Ding Ren Shen, Kim W. McIntyre, Kathleen M. Gillooly, Arthur M. Doweyko, John A. Newitt, John S. Sack, Hongjian Zhang, Susan E. Kiefer, Kevin Kish, Murray McKinnon, Joel C. Barrish, John H. Dodd, Gary L. Schieven, Katerina Leftheris	2010	19

About Kevin Kish

Kevin Kish is a scholar working on Molecular Biology, Organic Chemistry, Computational Theory and Mathematics, Hematology and Pharmacology, having authored 38 papers that have together received 2.0k indexed citations. Recurring topics across this work include Melanoma and MAPK Pathways (8 papers), Computational Drug Discovery Methods (6 papers), Wnt/β-catenin signaling in development and cancer (5 papers), Biochemical and Molecular Research (5 papers), Synthesis and biological activity (4 papers), Blood Coagulation and Thrombosis Mechanisms (4 papers), HIV/AIDS drug development and treatment (4 papers) and HIV Research and Treatment (3 papers). The work is most often cited by research in Hematology (433 citations), Genetics (295 citations), Endocrinology, Diabetes and Metabolism (384 citations), Molecular Biology (930 citations) and Organic Chemistry (381 citations). Kevin Kish has collaborated with scholars based in United States, Germany and Japan. Frequent co-authors include Susan E. Kiefer, Herbert E. Klei, Dianlin Xie, John S. Sack, Yaqun Zhang, John A. Newitt, John S. Tokarski, Michael Wittekind, Louis J. Lombardo and Janet Cheng. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Endocrinology and The Journal of Strength and Conditioning Research.

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