Peter Hunt

1.4k citations

42 papers · 1.0k · h-index 18

Impact in

Computational Theory and Mathematics top 2%
- Computational Drug Discovery Methods
Pharmacology top 10%
- Cholinesterase and Neurodegenerative Diseases
- Pharmacogenetics and Drug Metabolism

Papers in

Molecular Biology 24
- Receptor Mechanisms and Signaling 4
- Metabolomics and Mass Spectrometry Studies 4
- Protein Structure and Dynamics 3
Computational Theory and Mathematics 16
- Computational Drug Discovery Methods 16

Co-authors: Matthew Segall (13 shared papers)José L. Castro (2 shared papers)Mark S. Shearman (2 shared papers)Earl E. Clarke (2 shared papers)Alan Nadin (2 shared papers)Dirk Beher (2 shared papers)Huw D. Lewis (1 shared paper)Graeme I. Stevenson (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Chemical Information and Modeling (5 papers)Journal of Medicinal Chemistry (4 papers)Journal of Computer-Aided Molecular Design (3 papers)European Journal of Medicinal Chemistry (2 papers)
Partner nations: United Kingdom United States Switzerland

In The Last Decade

Peter Hunt

41 papers receiving 983 citations

Peers

Countries citing papers authored by Peter Hunt

Since Specialization

Citations

This map shows the geographic impact of Peter Hunt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter Hunt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter Hunt more than expected).

Fields of papers citing papers by Peter Hunt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter Hunt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter Hunt. The network helps show where Peter Hunt may publish in the future.

Co-authors

The 25 scholars most cited alongside Peter Hunt, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Peter Hunt Line = papers co-authored together Peter Hunt links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 42 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	L-685,458, an Aspartyl Protease Transition State Mimic, Is a Potent Inhibitor of Amyloid β-Protein Precursor γ-Secretase Activity Biochemistry ·Mark S. Shearman, Dirk Beher, Earl E. Clarke, Huw D. Lewis, Tim J. Harrison, Peter Hunt, Alan Nadin, Adrian L. Smith, Graeme I. Stevenson, José L. Castro	2000	312
2	Molecular Transformations as a Way of Finding and Exploiting Consistent Local QSAR Journal of Chemical Information and Modeling ·Robert P. Sheridan, Peter Hunt, J. Chris Culberson	2005	64
3	WhichP450: a multi-class categorical model to predict the major metabolising CYP450 isoform for a compound Journal of Computer-Aided Molecular Design ·Peter Hunt, Matthew Segall, Jonathan D. Tyzack	2018	56
4	Discovery of Functionally Selective 7,8,9,10-Tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABA_AReceptor Agonists at the α₃Subunit Journal of Medicinal Chemistry ·Michael G. N. Russell, Robert W. Carling, John Atack, Frances A. Bromidge, Susan M. Cook, Peter Hunt, Catherine Isted, Matt Lucas, Ruth M. McKernan, Andrew Mitchinson, Kevin W. Moore, Robert Narquizian, Alison Macaulay, David R. Thomas, Sally‐Anne Thompson, Keith A. Wafford, José L. Castro	2005	54
5	Imputation of Assay Bioactivity Data Using Deep Learning Journal of Chemical Information and Modeling ·Thomas M. Whitehead, Benedict Irwin, Peter Hunt, Matthew Segall, G. J. Conduit	2019	47
6	Predicting Regioselectivity and Lability of Cytochrome P450 Metabolism Using Quantum Mechanical Simulations Journal of Chemical Information and Modeling ·Jonathan D. Tyzack, Peter Hunt, Matthew Segall	2016	35
7	RELEASE OF BETAMETHASONE DERIVATIVES FROM OINTMENTS—IN VIVO AND IN VITRO STUDIES British Journal of Dermatology ·M J Busse, Peter Hunt, K. A. Lees, Peter Maggs, T. M. McCARTHY	1969	33
8	GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1–2 September 2014 Naunyn-Schmiedeberg s Archives of Pharmacology ·Alexander Heifetz, Gebhard F. X. Schertler, Roland Seifert, Christopher G. Tate, Patrick M. Sexton, Vsevolod V. Gurevich, Daniel Fourmy, Vadim Cherezov, Fiona H. Marshall, Richard Storer, Isabel Moraes, Irina G. Tikhonova, Christofer S. Tautermann, Peter Hunt, Tom Ceska, Simon T. Hodgson, Mike J. Bodkin, Shweta Singh, Richard Law, Philip C. Biggin	2015	28
9	Synthesis and Serotonergic Activity of 3-[2-(Pyrrolidin-1-yl)ethyl]indoles: Potent Agonists for the h5-HT_1D Receptor with High Selectivity over the h5-HT_1B Receptor Journal of Medicinal Chemistry ·Francine Sternfeld, Alexander R. Guiblin, Richard A. Jelley, Victor G. Matassa, Austin J. Reeve, Peter Hunt, Margaret S. Beer, Anne Heald, Josephine A. Stanton, Bindi Sohal, Alan P. Watt, Leslie J. Street	1999	25
10	Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 1: Quaternary amines Bioorganic & Medicinal Chemistry Letters ·Thomas A. Hunt, Hazel C. Atherton-Watson, Jake Axford, Stephen P. Collingwood, K. Coote, Brian J. Cox, Sarah Czarnecki, Henry Danahay, Nick Devereux, Catherine Howsham, Peter Hunt, Victoria L. Paddock, Derek Paisley, Alice C. Young	2011	23
11	1-Alkyl-1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-alkyl-oximes: a new class of potent orally active muscarinic agonists related to arecoline European Journal of Medicinal Chemistry ·E. TOJA, C Bonetti, A Butti, Peter Hunt, Marie-Chantal Fortin, F Barzaghi, M. L. Formento, A Maggioni, A Nencioni, Giulio Galliani	1991	23
12	Interactions of water soluble porphyrins with Z-poly(dG-dC) Nucleic Acids Research ·Robert F. Pasternack, David Sidney, Peter Hunt, Elizabeth A. Snowden, Julian H. Gibbs	1986	22
13	Predicting pK_a Using a Combination of Semi-Empirical Quantum Mechanics and Radial Basis Function Methods Journal of Chemical Information and Modeling ·Peter Hunt, Layla Hosseini-Gerami, Tomas Chrien, Jeffrey Plante, David J. Ponting, Matthew Segall	2020	22
14	3-(Piperazinylpropyl)indoles: Selective, Orally Bioavailable h5-HT_1DReceptor Agonists as Potential Antimigraine Agents Journal of Medicinal Chemistry ·Mark S. Chambers, Leslie J. Street, Simon Goodacre, Sarah C. Hobbs, Peter Hunt, Richard A. Jelley, Victor G. Matassa, Austin J. Reeve, Francine Sternfeld, Margaret S. Beer, Josephine A. Stanton, Denise Rathbone, Alan P. Watt, Angus M. MacLeod	1999	21
15	Aminoalkyl phenyl sulfones—a novel series of 5-HT7 receptor ligands Bioorganic & Medicinal Chemistry Letters ·Piotr Raubo, Margaret S. Beer, Peter Hunt, Ian T. Huscroft, Clare London, Josephine A. Stanton, Janusz J. Kulagowski	2005	19
16	Iodocyclisations of allyl- amidines and-ureas Tetrahedron Letters ·Peter Hunt, Christopher J. May, Christopher J. Moody	1988	19
17	Conserved residues within the putative active site of γ‐secretase differentially influence enzyme activity and inhibitor binding Journal of Neurochemistry ·Jonathan D.J. Wrigley, Emma J. Nunn, Omar Nyabi, Earl E. Clarke, Peter Hunt, Alan Nadin, Bart De Strooper, Mark S. Shearman, Dirk Beher	2004	18
18	The discovery of potent, orally bioavailable pyrazolo and triazolopyrimidine CXCR2 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·David W. Porter, Michelle Bradley, Zarin Brown, Riccardo Canova, Steven J. Charlton, Brian J. Cox, Peter Hunt, David Kolarik, Sarah Lewis, D. J. O'Connor, John Reilly, Carsten Spanka, Lauren Tedaldi, Simon J. Watson, Roland Wermuth, Neil J. Press	2013	17
19	Structure and modeling in the design of β‐ and γ‐secretase inhibitors Drug Development Research ·M. Katharine Holloway, Peter Hunt, Georgia B. McGaughey	2009	17
20	A comparison of semi-empirical SCF–MO and ab initio energy surfaces for the Beckmann rearrangement Journal of the Chemical Society Chemical Communications ·Peter Hunt, Henry S. Rzepa	1989	16

About Peter Hunt

Peter Hunt is a scholar working on Molecular Biology, Computational Theory and Mathematics, Spectroscopy, Organic Chemistry and Pharmacology, having authored 42 papers that have together received 1.0k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (16 papers), Analytical Chemistry and Chromatography (9 papers), Pharmacogenetics and Drug Metabolism (7 papers), Receptor Mechanisms and Signaling (4 papers), Asymmetric Synthesis and Catalysis (4 papers), Metabolomics and Mass Spectrometry Studies (4 papers), Alzheimer's disease research and treatments (3 papers) and Protein Structure and Dynamics (3 papers). The work is most often cited by research in Computational Theory and Mathematics (273 citations), Pharmacology (157 citations), Physiology (227 citations), Organic Chemistry (220 citations) and Molecular Biology (519 citations). Peter Hunt has collaborated with scholars based in United Kingdom, United States and Switzerland. Frequent co-authors include Matthew Segall, José L. Castro, Mark S. Shearman, Earl E. Clarke, Alan Nadin, Dirk Beher, Huw D. Lewis, Graeme I. Stevenson, Tim J. Harrison and Adrian L. Smith. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Chemical Information and Modeling, Journal of Medicinal Chemistry, Journal of Computer-Aided Molecular Design and European Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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