Tom Ceska

1.4k citations

16 papers · 703 · h-index 13

Impact in

Physiology top 5%
- Adenosine and Purinergic Signaling
Structural Biology top 10%

Papers in

Molecular Biology 8
- Receptor Mechanisms and Signaling 3
- Glycosylation and Glycoproteins Research 1
- 14-3-3 protein interactions 1
Radiology, Nuclear Medicine and Imaging 7
- Monoclonal and Polyclonal Antibodies Research 7

Co-authors: Florence Lebon (3 shared papers)Alastair D. G. Lawson (5 shared papers)David McMillan (4 shared papers)Brian K. Kobilka (2 shared papers)Zara A. Sands (2 shared papers)Bingfa Sun (2 shared papers)Martyn Wood (2 shared papers)Tong Sun Kobilka (2 shared papers)
Journals: Nature Communications (4 papers)Communications Biology (1 paper)Journal of Biological Chemistry (1 paper)Biochemical Society Transactions (1 paper)Nature (1 paper)
Partner nations: United Kingdom United States Belgium

In The Last Decade

Tom Ceska

16 papers receiving 693 citations

Peers

Countries citing papers authored by Tom Ceska

Since Specialization

Citations

This map shows the geographic impact of Tom Ceska's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tom Ceska with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tom Ceska more than expected).

Fields of papers citing papers by Tom Ceska

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tom Ceska. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tom Ceska. The network helps show where Tom Ceska may publish in the future.

Co-authors

The 25 scholars most cited alongside Tom Ceska, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tom Ceska Line = papers co-authored together Tom Ceska links everyone, so they are left out of the graph.

All Works

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16 of 16 papers shown

#	Work
1	Crystal structure of the adenosine A _2A receptor bound to an antagonist reveals a potential allosteric pocket Proceedings of the National Academy of Sciences ·Bingfa Sun, Priti Bachhawat, Matthew Chu, Martyn Wood, Tom Ceska, Zara A. Sands, Joël Mercier, Florence Lebon, Tong Sun Kobilka, Brian K. Kobilka	2017	105
2	Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A Nature ·Roger Benoit, Daniel Frey, Manuel Hilbert, Josta T. Kevenaar, Mara M. Wieser, Christian U. Stirnimann, David McMillan, Tom Ceska, Florence Lebon, Rolf Jaussi, Michel O. Steinmetz, Gebhard F. X. Schertler, Casper C. Hoogenraad, Guido Capitani, Richard A. Kammerer	2013	103
3	Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer Nature Communications ·James P. O’Connell, John Porter, Boris Kroeplien, Tim Norman, Stephen Rapecki, Rachel E. Davis, David McMillan, T.L. Arakaki, Alex B. Burgin, David Fox, Tom Ceska, Fabien Lecomte, Alison Maloney, Alex Vugler, Bruce Carrington, Benjamin P. Cossins, Tim Bourne, Alastair D. G. Lawson	2019	89
4	Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF Nature Communications ·David McMillan, C. Martinez-Fleites, John Porter, David Fox, Rachel E. Davis, Prashant Mori, Tom Ceska, Bruce Carrington, Alastair D. G. Lawson, Tim Bourne, James P. O’Connell	2021	66
5	Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab Journal of Biological Chemistry ·Anna M. Davies, Elizabeth G. Allan, Anthony H. Keeble, Jean Delgado, Benjamin P. Cossins, Alkistis Mitropoulou, Marie O. Y. Pang, Tom Ceska, Andrew J. Beavil, Graham Craggs, Marta Westwood, Alistair J. Henry, James M. McDonnell, Brian J. Sutton	2017	63
6	Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life mAbs ·Ralph Adams, Laura Griffin, Joanne Compson, Mark Jairaj, Terry Baker, Tom Ceska, Shauna West, Oliver Zaccheo, Emma Davé, Alastair D. G. Lawson, David P. Humphreys, Sam Heywood	2016	46
7	Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist Nature Communications ·Bingfa Sun, Dan Feng, Matthew Ling-Hon Chu, I. Fish, Silvia Lovera, Zara A. Sands, Sebastian Kelm, Anne Valade, Martyn Wood, Tom Ceska, Tong Sun Kobilka, Florence Lebon, Brian K. Kobilka	2021	40
8	Cryo-EM in drug discovery Biochemical Society Transactions ·Tom Ceska, Chun‐wa Chung, Rob Cooke, Chris Phillips, Pamela A. Williams	2019	37
9	Direct observation of DNA threading in flap endonuclease complexes Nature Structural & Molecular Biology ·Faizah A. AlMalki, Claudia S. Flemming, Jing Zhang, Min Feng, Svetlana E. Sedelnikova, Tom Ceska, John B. Rafferty, Jon R. Sayers, Peter J. Artymiuk	2016	32
10	GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1–2 September 2014 Naunyn-Schmiedeberg s Archives of Pharmacology ·Alexander Heifetz, Gebhard F. X. Schertler, Roland Seifert, Christopher G. Tate, Patrick M. Sexton, Vsevolod V. Gurevich, Daniel Fourmy, Vadim Cherezov, Fiona H. Marshall, Richard Storer, Isabel Moraes, Irina G. Tikhonova, Christofer S. Tautermann, Peter Hunt, Tom Ceska, Simon T. Hodgson, Mike J. Bodkin, Shweta Singh, Richard Law, Philip C. Biggin	2015	31
11	Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping Scientific Reports ·Xiaofeng Liu, Richard D. Taylor, Laura Griffin, Shu-Fen Coker, Ralph Adams, Tom Ceska, Jiye Shi, Alastair D. G. Lawson, Terry Baker	2017	30
12	A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF Nature Communications ·Daniel Lightwood, Rebecca Munro, John Porter, David McMillan, Bruce Carrington, Alison Turner, Anthony Scott-Tucker, Elizabeth S Hickford, Antje Schmidt, David Fox, Alison Maloney, Tom Ceska, Tim Bourne, James P. O’Connell, Alastair D. G. Lawson	2021	24
13	Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis Communications Biology ·A.J. Higgins, Alex J. Flynn, Anaïs Marconnet, Laura J. Musgrove, Vincent L. G. Postis, Jonathan D. Lippiat, Chun‐wa Chung, Tom Ceska, Manuela Zoonens, Frank Sobott, Stephen P. Muench	2021	18
14	Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1 ACS Medicinal Chemistry Letters ·Adrian Hall, Jan Abendroth, Madison Bolejack, Tom Ceska, Sylvie Dell’Aiera, Victoria Ellis, David J. Fox, Cyril François, Muigai M. Muruthi, Camille Prével, Karine G. Poullennec, Sergei Romanov, Anne Valade, Alain Vanbellinghen, Jason K. Yano, Martine Geraerts	2022	8
15	Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization Acta Crystallographica Section F Structural Biology Communications ·Alkistis Mitropoulou, Tom Ceska, James T. Heads, Andrew J. Beavil, Alistair J. Henry, James M. McDonnell, Brian J. Sutton, Anna M. Davies	2020	6
16	P150 DETAILING THE NOVEL STRUCTURE OF THE BIOPHARMACEUTICAL CERTOLIZUMAB PEGOL Bengt Smith, Tom Ceska, Alistair Henry, James Heads, Anthony Turner, Sam Heywood, James E. O’Hara, Andrew Nesbitt	2008	5

About Tom Ceska

Tom Ceska is a scholar working on Molecular Biology, Radiology, Nuclear Medicine and Imaging, Immunology, Cellular and Molecular Neuroscience and Structural Biology, having authored 16 papers that have together received 703 indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (7 papers), Receptor Mechanisms and Signaling (3 papers), Neuropeptides and Animal Physiology (3 papers), Advanced Electron Microscopy Techniques and Applications (2 papers), Cell Adhesion Molecules Research (2 papers), Immune Response and Inflammation (2 papers), Glycosylation and Glycoproteins Research (1 paper) and 14-3-3 protein interactions (1 paper). The work is most often cited by research in Physiology (60 citations), Structural Biology (17 citations), Cellular and Molecular Neuroscience (140 citations), Neurology (92 citations) and Immunology and Allergy (37 citations). Tom Ceska has collaborated with scholars based in United Kingdom, United States and Belgium. Frequent co-authors include Florence Lebon, Alastair D. G. Lawson, David McMillan, Brian K. Kobilka, Zara A. Sands, Bingfa Sun, Martyn Wood, Tong Sun Kobilka, Bruce Carrington and David Fox. Their work appears in journals such as Nature Communications, Communications Biology, Journal of Biological Chemistry, Biochemical Society Transactions and Nature.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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