John Wityak

4.5k citations

46 papers · 1.4k · h-index 24

Impact in

Organic Chemistry top 5%
- Synthesis and biological activity
- Click Chemistry and Applications
- Synthesis and Biological Evaluation
- Quinazolinone synthesis and applications
Immunology and Allergy top 5%
- Cell Adhesion Molecules Research

Papers in

Molecular Biology 18
- Melanoma and MAPK Pathways 6
- Receptor Mechanisms and Signaling 4
Cellular and Molecular Neuroscience 12
- Genetic Neurodegenerative Diseases 8

Co-authors: Shaker A. Mousa (11 shared papers)Celia Dominguez (10 shared papers)Joel C. Barrish (9 shared papers)James C. Lin (8 shared papers)Arthur M. Doweyko (7 shared papers)Ruth R. Wexler (10 shared papers)Jagabandhu Das (7 shared papers)Gary L. Schieven (7 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (18 papers)Journal of Medicinal Chemistry (6 papers)PLoS ONE (3 papers)Journal of Cardiovascular Pharmacology (3 papers)The Journal of Organic Chemistry (2 papers)
Partner nations: United States Germany Japan

In The Last Decade

John Wityak

46 papers receiving 1.4k citations

Peers

Countries citing papers authored by John Wityak

Since Specialization

Citations

This map shows the geographic impact of John Wityak's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Wityak with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Wityak more than expected).

Fields of papers citing papers by John Wityak

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Wityak. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Wityak. The network helps show where John Wityak may publish in the future.

Co-authors

The 25 scholars most cited alongside John Wityak, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John Wityak Line = papers co-authored together John Wityak links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 46 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das, Robert V. Moquin, James C. Lin, Chunjian Liu, Arthur M. Doweyko, Henry F. DeFex, Qiong Fang, Suhong Pang, Sidney Pitt, Ding Ren Shen, Gary L. Schieven, Joel C. Barrish, John Wityak	2003	92
2	Isoxazolines as Potent Antagonists of the Integrin α_vβ₃ Journal of Medicinal Chemistry ·William J. Pitts, John Wityak, Joanne M. Smallheer, A. Ewa Tobin, James W. Jetter, Jennifer S. Buynitsky, Patricia Harlow, Kimberly A. Solomon, Martha H. Corjay, Shaker A. Mousa, Ruth R. Wexler, Prabhakar K. Jadhav	1999	75
3	Synthesis of 1,3-Diynes Using Palladium-Copper Catalysis Synthetic Communications ·John Wityak, John B. Chan	1991	74
4	A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease PLoS ONE ·Daniel G. Todd, Ian Gowers, Simon DOWLER, Michael D. Wall, George McAllister, David F. Fischer, Sipke Dijkstra, Silvina A. Fratantoni, Rhea van de Bospoort, Jessica Veenman-Koepke, Geraldine Flynn, Jamshid Arjomand, Celia Dominguez, Ignacio Muñoz-Sanjuán, John Wityak, Jonathan Bard	2014	70
5	A Profiling Platform for the Characterization of Transglutaminase 2 (TG2) Inhibitors SLAS DISCOVERY ·Sabine Schaertl, Michael E. Prime, John Wityak, Celia Dominguez, Ignacio Muñoz-Sanjuán, Robert E. Pacifici, Stephen M. Courtney, Andreas H. Scheel, Douglas Macdonald	2010	66
6	Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das, Joseph A. Furch, Chunjian Liu, Robert V. Moquin, James C. Lin, Steven H. Spergel, Kim W. McIntyre, David J. Shuster, Kathleen O'Day, Becky Penhallow, Chen-Yi Hung, Arthur M. Doweyko, Amrita V. Kamath, Hongjian Zhang, Punit Marathe, Steven B. Kanner, Tai-An Lin, John H. Dodd, Joel C. Barrish, John Wityak	2006	65
7	Discovery of Potent Isoxazoline Glycoprotein IIb/IIIa Receptor Antagonists Journal of Medicinal Chemistry ·John Wityak, Thais M. Sielecki, Donald Pinto, George Emmett, Jean Y. Sze, Jie Liu, A. Ewa Tobin, Shuaige Wang, Biao Jiang, Philip Ma, Shaker A. Mousa, Ruth R. Wexler, Richard E. Olson	1997	64
8	Synthesis of Thrombin Inhibitor DuP 714 The Journal of Organic Chemistry ·John Wityak, Richard A. Earl, Matthew M. Abelman, Yvonne B. Bethel, Barbara N. Fisher, Goss S. Kauffman, Charles A. Kettner, Philip Ma, Janice L. McMillan	1995	58
9	5-Cyanopyrimidine Derivatives as a Novel Class of Potent, Selective, and Orally Active Inhibitors of p38α MAP Kinase Journal of Medicinal Chemistry ·Chunjian Liu, Stephen T. Wrobleski, James C. Lin, Gulzar Ahmed, Axel Metzger, John Wityak, Kathleen M. Gillooly, David J. Shuster, Kim W. McIntyre, Sidney Pitt, Ding Ren Shen, Rosemary F. Zhang, Hongjian Zhang, Arthur M. Doweyko, David Diller, Ian Henderson, Joel C. Barrish, John H. Dodd, Gary L. Schieven, Katerina Leftheris	2005	55
10	Identification of chemokine receptor CCR4 antagonist Bioorganic & Medicinal Chemistry Letters ·Ashok V. Purandare, Aiming Gao, Honghe Wan, John E. Somerville, Christine Burke, Carrie L. Seachord, Wayne Vaccaro, John Wityak, Michael A. Poss	2005	54
11	Molecular design, synthesis, and structure–Activity relationships leading to the potent and selective p56lck inhibitor BMS-243117 Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das, James C. Lin, Robert V. Moquin, Zhongqi Shen, Steven H. Spergel, John Wityak, Arthur M. Doweyko, Henry F. DeFex, Qiong Fang, Suhong Pang, Sidney Pitt, Ding Ren Shen, Gary L. Schieven, Joel C. Barrish	2003	47
12	N-Acylthiadiazolines, a New Class of Liver X Receptor Agonists with Selectivity for LXRβ Journal of Medicinal Chemistry ·Valentina Molteni, Xiaolin Li, Juliet Nabakka, Fang Liang, John Wityak, Alan Koder, Leo Vargas, Russell D. Romeo, Nico Mitro, Puiying A. Mak, H. Martin Seidel, Jennifer A. Haslam, Donald Chow, Tove Tuntland, Tracy A. Spalding, Ansgar Brock, Michelle N. Bradley, Antonio Castrillo, Peter Tontonoz, Enrique Sáez	2007	44
13	Novel nonpeptide antiplatelet glycoprotein llb/llla receptor antagonist, DMP754 Coronary Artery Disease ·Shaker A. Mousa, Mark S. Forsythe, William Lorelli, Jeffrey M. Bozarth, Chu‐Biao Xue, John Wityak, Thais M. Sielecki, Rick E. Olson, William F. DeGrado, Ram P. Kapil, Munir Hussain, Ruth R. Wexler, Martin Thoolen, Thomas M. Reilly	1996	41
14	A 1,3-dipolar cycloaddition route to the 3(R)- and 3(S)-hydroxy-2(S)-arginines The Journal of Organic Chemistry ·John Wityak, Steven J. Gould, Scott J. Hein, Douglas A. Keszler	1987	41
15	Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck Bioorganic & Medicinal Chemistry Letters ·John Wityak, Jagabandhu Das, Robert V. Moquin, Zhongqi Shen, James C. Lin, Ping Chen, Arthur M. Doweyko, Sidney Pitt, Suhong Pang, Ding Ren Shen, Qiong Fang, H. Fex, Gary L. Schieven, Steven B. Kanner, Joel C. Barrish	2003	39
16	Novel Bisaryl Substituted Thiazoles and Oxazoles as Highly Potent and Selective Peroxisome Proliferator-Activated Receptor δ Agonists Journal of Medicinal Chemistry ·Robert Epple, Christopher Cow, Xie Yongping, Mihai Azimioara, Ross Russo, Xing Wang, John Wityak, Donald S. Karanewsky, Tove Tuntland, Vân Nguyên-Trân, Cara Cuc Ngo, David Huang, Enrique Sáez, Tracy A. Spalding, Andrea Gerken, Maya Iskandar, H. Martin Seidel, Shin‐Shay Tian	2009	36
17	Quantifying autophagy using novel LC3B and p62 TR-FRET assays PLoS ONE ·Alberto Bresciani, Maria Carolina Spiezia, Roberto Boggio, Cristina Cariulo, Anja Nordheim, Roberta Altobelli, Kirsten Kuhlbrodt, Celia Dominguez, Ignacio Muñoz-Sanjuán, John Wityak, Valentina Fodale, Deanna M. Marchionini, Andreas Weiss	2018	35
18	SAR Development of Lysine-Based Irreversible Inhibitors of Transglutaminase 2 for Huntington's Disease ACS Medicinal Chemistry Letters ·John Wityak, Michael E. Prime, Frederick A. Brookfield, Stephen M. Courtney, Sayeh Erfan, Siw F. Johnsen, Peter Johnson, Marie Li, Richard W. Marston, Laura Reed, Darshan G. Vaidya, Sabine Schaertl, Anna Pedret‐Dunn, Maria Beconi, Douglas Macdonald, Ignacio Muñoz-Sanjuán, Celia Dominguez	2012	31
19	Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors Bioorganic & Medicinal Chemistry Letters ·Jagabandhu Das, Chunjian Liu, Robert V. Moquin, James C. Lin, Joseph A. Furch, Steven H. Spergel, Kim W. McIntyre, David J. Shuster, Kathleen O'Day, Becky Penhallow, Chen-Yi Hung, Steven B. Kanner, Tai-An Lin, John H. Dodd, Joel C. Barrish, John Wityak	2006	31
20	Orally Active Isoxazoline GPIIb/IIIa Antagonists Cardiovascular Drug Reviews ·Shaker A. Mousa, John Wityak	1998	28

About John Wityak

John Wityak is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Organic Chemistry, Hematology and Surgery, having authored 46 papers that have together received 1.4k indexed citations. Recurring topics across this work include Platelet Disorders and Treatments (8 papers), Genetic Neurodegenerative Diseases (8 papers), Antiplatelet Therapy and Cardiovascular Diseases (7 papers), Melanoma and MAPK Pathways (6 papers), Heparin-Induced Thrombocytopenia and Thrombosis (5 papers), Receptor Mechanisms and Signaling (4 papers), Monoclonal and Polyclonal Antibodies Research (4 papers) and Neurological disorders and treatments (4 papers). The work is most often cited by research in Organic Chemistry (582 citations), Immunology and Allergy (93 citations), Hematology (166 citations), Toxicology (30 citations) and Molecular Biology (538 citations). John Wityak has collaborated with scholars based in United States, Germany and Japan. Frequent co-authors include Shaker A. Mousa, Celia Dominguez, Joel C. Barrish, James C. Lin, Arthur M. Doweyko, Ruth R. Wexler, Jagabandhu Das, Gary L. Schieven, Robert V. Moquin and Ding Ren Shen. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, PLoS ONE, Journal of Cardiovascular Pharmacology and The Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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John Wityak

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