John E. Macor

6.2k citations

163 papers · 3.3k · h-index 29

Impact in

Organic Chemistry top 1%
- Synthesis and Biological Evaluation
- Catalytic C–H Functionalization Methods
- Asymmetric Synthesis and Catalysis
Cellular and Molecular Neuroscience top 2%
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research

Papers in

Molecular Biology 80
- Receptor Mechanisms and Signaling 31
Organic Chemistry 77
- Synthesis and Biological Evaluation 25
- Asymmetric Synthesis and Catalysis 20
- Chemical Reaction Mechanisms 17
- Chemical synthesis and alkaloids 16

Co-authors: Kevin Ryan (16 shared papers)Edward C. Taylor (6 shared papers)Michael E. Newman (8 shared papers)Gene M. Dubowchik (30 shared papers)B. Kenneth Koe (10 shared papers)Edward C. Taylor (4 shared papers)James Heym (3 shared papers)Ronald J. Post (12 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (53 papers)Tetrahedron Letters (24 papers)Journal of Medicinal Chemistry (18 papers)The Journal of Organic Chemistry (11 papers)ACS Medicinal Chemistry Letters (7 papers)
Partner nations: United States Germany India

In The Last Decade

John E. Macor

161 papers receiving 3.2k citations

Peers

Countries citing papers authored by John E. Macor

Since Specialization

Citations

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Fields of papers citing papers by John E. Macor

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Macor. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Macor. The network helps show where John E. Macor may publish in the future.

Co-authors

The 25 scholars most cited alongside John E. Macor, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John E. Macor Line = papers co-authored together John E. Macor links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 163 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1) agonist and rotationally restricted phenolic analog of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole Journal of Medicinal Chemistry* ·John E. Macor, (unknown), James Heym, Jeffrey L. Ives, Lorraine A. Lebel, Michael E. Newman, J.A. Nielsen, Kevin Ryan, David W. Schulz	1990	138
2	The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist Bioorganic & Medicinal Chemistry Letters ·John E. Macor, David Gurley, Thomas H. Lanthorn, James T. Loch, Robert A. Mack, G. B. MULLEN, Oahn Tran, Nicole C. Wright, John Gordon	2001	131
3	Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core Bioorganic & Medicinal Chemistry Letters ·Prasanna Sivaprakasam, Xiaojun Han, Rita L. Civiello, Swanee Jacutin-Porte, Kevin Kish, Matt Pokross, H.A. Lewis, Nazia Ahmed, Nicolas Szapiel, John A. Newitt, Eric T. Baldwin, Hong Xiao, Carol Krause, Hyunsoo Park, Michelle Nophsker, Jonathan Lippy, Catherine R. Burton, David R. Langley, John E. Macor, Gene M. Dubowchik	2015	102
4	Enantioselective Synthesis of a Highly Potent Selective Serotonin Reuptake Inhibitor. An Application of Imidazolidinone Catalysis to the Alkylation of Indoles with an α,β-Disubstituted α,β-Unsaturated Aldehyde Organic Letters ·Dalton King, Zhaoxing Meng, Derek J. Denhart, Ronald J. Mattson, Roy Kimura, Dedong Wu, Qi Gao, John E. Macor	2005	102
5	Biochemical and behavioral studies of the 5‐HT_1B receptor agonist, CP‐94,253 Drug Development Research ·B. Kenneth Koe, Jann A. Nielsen, John E. Macor, James Heym	1992	95
6	Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer’s Mouse Phenotypes Cell Reports ·Laura T. Haas, Santiago V. Salazar, Levi M. Smith, Helen R. Zhao, Timothy Cox, Charlotte Herber, Andrew P. Degnan, Anand Balakrishnan, John E. Macor, Charles F. Albright, Stephen M. Strittmatter	2017	86
7	Annual Reports in Medicinal Chemistry Medical Entomology and Zoology ·Cornelius K. Cain, Annette M. Doherty, Anthony Wood, John E. Macor, Manoj C. Desai	2002	74
8	Discovery of (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (BMS-927711): An Oral Calcitonin Gene-Related Peptide (CGRP) Antagonist in Clinical Trials for Treating Migraine Journal of Medicinal Chemistry ·Guanglin Luo, Ling Chen, Charles M. Conway, Rex Denton, Deborah Keavy, Laura J. Signor, Walter A. Kostich, Kimberley A. Lentz, Kenneth S. Santone, Richard Schartman, Marc Browning, Gary Tong, John G. Houston, Gene M. Dubowchik, John E. Macor	2012	72
9	Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics Journal of Medicinal Chemistry ·Natesan Murugesan, Zhengxiang Gu, Leena Fadnis, John E. Tellew, Rose A. Baska, Yifan Yang, Sophie Beyer, Hossain Monshizadegan, Kenneth E.J. Dickinson, Maria Valentine, W. Griffith Humphreys, Shih-Jung Lan, William R. Ewing, Kenneth E. Carlson, Mark C. Kowala, Robert Zahler, John E. Macor	2004	67
10	Intramolecular diels-alder reactions of 1,2,4-triazines. Tetrahedron ·Edward C. Taylor, John E. Macor, Joseph L. Pont	1987	60
11	Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors Journal of Medicinal Chemistry ·Guanglin Luo, Ling Chen, Catherine R. Burton, Hong Xiao, Prasanna Sivaprakasam, Carol Krause, Yang Cao, Nengyin Liu, Jonathan Lippy, Wendy Clarke, Kimberly J. Snow, Joseph Raybon, Vinod Arora, Matt Pokross, Kevin Kish, H.A. Lewis, David R. Langley, John E. Macor, Gene M. Dubowchik	2016	58
12	Discovery of (R)-4-(8-Fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): A Potent Antagonist of the Human Calcitonin Gene-Related Peptide Receptor for Migraine with Rapid and Efficient Intranasal Exposure Journal of Medicinal Chemistry ·Andrew P. Degnan, Prasad V. Chaturvedula, Charles M. Conway, Deborah A. Cook, Carl D. Davis, Rex Denton, Xiaojun Han, Robert Macci, Neil Mathias, Paul Moench, Sokhom S. Pin, Shelly X. Ren, Richard Schartman, Laura J. Signor, George Thalody, Kimberly A. Widmann, Cen Xu, John E. Macor, Gene M. Dubowchik	2008	54
13	Discovery of Tyrosine-Based Potent and Selective Melanocortin-1 Receptor Small-Molecule Agonists with Anti-inflammatory Properties Journal of Medicinal Chemistry ·Timothy F. Herpin, Guixue Yu, Kenneth E. Carlson, George Morton, Ximao Wu, Liya Kang, Huji Tuerdi, Ashish Khanna, John S. Tokarski, R. Michael Lawrence, John E. Macor	2003	52
14	Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase Bioorganic & Medicinal Chemistry Letters ·David S. Weinstein, Wen Liu, Zhengxiang Gu, Charles M. Langevine, Khehyong Ngu, Leena Fadnis, Donald W. Combs, Doree Sitkoff, Saleem Ahmad, Shaobin Zhuang, Xing Chen, Feng-Lai Wang, Deborah A. Loughney, Karnail S. Atwal, Robert Zahler, John E. Macor, Cort S. Madsen, Natesan Murugesan	2005	46
15	5-Carboxamido-tryptamine, CP-122,288 and dihydroergotamine but not sumatriptan, CP-93,129, and serotonin-5-O-carboxymethyl-glycyl -tyrosinamide block dural plasma protein extravasation in knockout mice that lack 5-hydroxytryptamine1B receptors. Molecular Pharmacology ·Xian‐Jie Yu, Christian Waeber, Nathalie Castanon, K. Scearce, Hen R, John E. Macor, J. Chauveau, M A Moskowitz, (unknown)	1996	45
16	Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): A potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery Bioorganic & Medicinal Chemistry Letters ·Prasad V. Chaturvedula, Stephen E. Mercer, Sokhom S. Pin, George Thalody, Cen Xu, Charlie M. Conway, Deborah Keavy, Laura J. Signor, Glenn H. Cantor, Neil Mathias, Paul Moench, Rex Denton, Robert Macci, Richard Schartman, Valerie Whiterock, Carl D. Davis, John E. Macor, Gene M. Dubowchik	2013	43
17	Quinolines as extremely potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction Bioorganic & Medicinal Chemistry Letters ·Yingzhi Bi, Patrick Stoy, Leonard P. Adam, Bin He, John Krupinski, Diane E. Normandin, Ron Pongrac, Laurie Seliger, Andrew J. Watson, John E. Macor	2004	43
18	Synthesis and Use of 5-Vinyl-1,2,4-oxadiazoles as Michael Acceptors. A Rapid Synthesis of the Potent Muscarinic Agonist L-670,548 The Journal of Organic Chemistry ·John E. Macor, Timothy Ordway, Robert L. Smith, Patrick R. Verhoest, Robert A. Mack	1996	41
19	Discovery, Synthesis, and Preclinical Characterization ofN-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (VU0418506), a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu₄) ACS Chemical Neuroscience ·Darren W. Engers, Anna L. Blobaum, Rocco D. Gogliotti, Yiu‐Yin Cheung, James M. Salovich, Pedro M. García-Barrantes, J. Scott Daniels, Ryan D. Morrison, Carrie K. Jones, Matthew G. Soars, Xiaoliang Zhuo, Jeremy Hurley, John E. Macor, Joanne J. Bronson, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins	2016	39
20	N-3-Substituted Imidazoquinazolinones: Potent and Selective PDE5 Inhibitors as Potential Agents for Treatment of Erectile Dysfunction Journal of Medicinal Chemistry ·David P. Rotella, Zhong Sun, Yeheng Zhu, John Krupinski, Ronald Pongrac, Laurie Seliger, Diane E. Normandin, John E. Macor	2000	37

About John E. Macor

John E. Macor is a scholar working on Molecular Biology, Organic Chemistry, Cellular and Molecular Neuroscience, Psychiatry and Mental health and Pharmacology, having authored 163 papers that have together received 3.3k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (31 papers), Synthesis and Biological Evaluation (25 papers), Neuroscience and Neuropharmacology Research (23 papers), Neuropeptides and Animal Physiology (22 papers), Asymmetric Synthesis and Catalysis (20 papers), Migraine and Headache Studies (18 papers), Chemical Reaction Mechanisms (17 papers) and Chemical synthesis and alkaloids (16 papers). The work is most often cited by research in Organic Chemistry (1.5k citations), Cellular and Molecular Neuroscience (685 citations), Pharmacology (391 citations), Psychiatry and Mental health (331 citations) and Pharmaceutical Science (137 citations). John E. Macor has collaborated with scholars based in United States, Germany and India. Frequent co-authors include Kevin Ryan, Edward C. Taylor, Michael E. Newman, Gene M. Dubowchik, B. Kenneth Koe, Edward C. Taylor, James Heym, Ronald J. Post, Lorraine A. Lebel and Robert A. Mack. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Tetrahedron Letters, Journal of Medicinal Chemistry, The Journal of Organic Chemistry and ACS Medicinal Chemistry Letters.

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