Philip D. Stein

1.6k citations

44 papers · 906 · h-index 18

Impact in

Organic Chemistry top 5%
- Synthesis and Catalytic Reactions
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
- Catalytic C–H Functionalization Methods
Physiology top 10%
- Nitric Oxide and Endothelin Effects

Papers in

Molecular Biology 14
- Receptor Mechanisms and Signaling 5
- ATP Synthase and ATPases Research 4
- Mitochondrial Function and Pathology 4
Cardiology and Cardiovascular Medicine 11
- Cardiac electrophysiology and arrhythmias 4

Co-authors: Alan P. Kozikowski (4 shared papers)Eddie C.‐K. Liu (13 shared papers)Suzanne Moreland (6 shared papers)John T. Hunt (4 shared papers)David Floyd (4 shared papers)Patricia M. Rose (3 shared papers)Maria L. Webb (8 shared papers)Natesan Murugesan (3 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (13 papers)Journal of Medicinal Chemistry (7 papers)Cardiovascular Research (2 papers)The Journal of Organic Chemistry (2 papers)Journal of the American Chemical Society (2 papers)
Partner nations: United States Germany Sweden

In The Last Decade

Philip D. Stein

42 papers receiving 840 citations

Peers

Countries citing papers authored by Philip D. Stein

Since Specialization

Citations

This map shows the geographic impact of Philip D. Stein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip D. Stein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip D. Stein more than expected).

Fields of papers citing papers by Philip D. Stein

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip D. Stein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip D. Stein. The network helps show where Philip D. Stein may publish in the future.

Co-authors

The 25 scholars most cited alongside Philip D. Stein, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Philip D. Stein Line = papers co-authored together Philip D. Stein links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 44 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The Discovery of Sulfonamide Endothelin Antagonists and the Development of the Orally Active ETA Antagonist 5-(Dimethylamino)-N-(3,4-dimethyl-5- isoxazolyl)-1-naphthalenesulfonamide Journal of Medicinal Chemistry ·Philip D. Stein, John T. Hunt, David Floyd, Suzanne Moreland, Kenneth E.J. Dickinson, Caroline Mitchell, Eddie C.‐K. Liu, Maria L. Webb, Natesan Murugesan	1994	112
2	Selective blockade of the endothelin subtype A receptor decreases early atherosclerosis in hamsters fed cholesterol. PubMed ·Mark C. Kowala, Patricia M. Rose, Philip D. Stein, N. L. Goller, Ron Recce, Sophie Beyer, Maria Valentine, David Barton, Stephen K. Durham	1995	104
3	The INOC route to carbocyclics: a formal total synthesis of (.+-.)-sarkomycin Journal of the American Chemical Society ·Alan P. Kozikowski, Philip D. Stein	1982	103
4	Intramolecular nitrile oxide cycloaddition route to carbocyclics: a formal total synthesis of PGF2.alpha. The Journal of Organic Chemistry ·Alan P. Kozikowski, Philip D. Stein	1984	62
5	Hit-to-Lead Studies for the Antimalarial Tetrahydroisoquinolone Carboxanilides Journal of Medicinal Chemistry ·David Floyd, Philip D. Stein, Zheng Wang, Jian Liu, Steve Castro, Julie Clark, Michele Connelly, Fangyi Zhu, Gloria Holbrook, Amy Matheny, Martina Sigal, Jaeki Min, Rajkumar Dhinakaran, Senthil Kumar Krishnan, Sridevi Bashyum, Spencer Knapp, R. Kiplin Guy	2016	45
6	BMS-182874 is a selective, nonpeptide endothelin ETA receptor antagonist. Journal of Pharmacology and Experimental Therapeutics ·Marjorie Webb, J. Eileen Bird, Eddie C.‐K. Liu, Patricia M. Rose, R Serafino, Philip D. Stein, Suzanne Moreland	1995	35
7	Structure-activity relationships of monocyclic endothelin analogs Bioorganic & Medicinal Chemistry Letters ·John T. Hunt, Ving G. Lee, Philip D. Stein, Anders Hedberg, Eddie C.‐K. Liu, Diane M. McMullen, Suzanne Moreland	1991	30
8	Three-Dimensional Quantitative Structure-Activity Relationships of Sulfonamide Endothelin Inhibitors Journal of Medicinal Chemistry ·Stanley R. Krystek, John T. Hunt, Philip D. Stein, Terry R. Stouch	1995	28
9	Discovery and Structure-Activity Relationships of Sulfonamide ETA-Selective Antagonists Journal of Medicinal Chemistry ·Philip D. Stein, David Floyd, Sharon N. Bisaha, Joyce Dickey, Ravindar N. Girotra, Jack Z. Gougoutas, Michael R. Kozlowski, Ving G. Lee, Eddie C.‐K. Liu	1995	28
10	Design, Structure−Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors Journal of Medicinal Chemistry ·Yan Shi, Doree Sitkoff, Jing Zhang, Herbert E. Klei, Kevin Kish, Eddie C.‐K. Liu, Karen S. Hartl, Steve M. Seiler, Ming Chang, Christine Huang, Sonia Youssef, Thomas E. Steinbacher, William A. Schumacher, Nyeemah Grazier, Andrew T. Pudzianowski, Atsu Apedo, Lorell Discenza, Joseph Yanchunas, Philip D. Stein, Karnail S. Atwal	2008	27
11	One-Pot Synthesis and Conformational Features ofN,N‘-Disubstituted Ketene Aminals The Journal of Organic Chemistry ·Yan Shi, Jing Zhang, Nyeemah Grazier, Philip D. Stein, Karnail S. Atwal, Sarah C. Traeger, Sharon P. Callahan, Mary F. Malley, Michael A. Galella, Jack Z. Gougoutas	2003	24
12	Biphenylsulfonamide Endothelin Receptor Antagonists. 2. Discovery of 4‘-Oxazolyl Biphenylsulfonamides as a New Class of Potent, Highly Selective ET_A Antagonists Journal of Medicinal Chemistry ·Natesan Murugesan, Zhengxiang Gu, Philip D. Stein, Steven H. Spergel, Arvind Mathur, Leslie Leith, Eddie C.‐K. Liu, Rongan Zhang, Eileen Bird, Tom Waldron, Anthony M. Marino, Richard A. Morrison, Maria L. Webb, Suzanne Moreland, Joel C. Barrish	2000	24
13	Benzodiazepine-based selective inhibitors of mitochondrial F1F0 ATP hydrolase Bioorganic & Medicinal Chemistry Letters ·Lawrence G. Hamann, Charles Z. Ding, Arthur V. Miller, Cort S. Madsen, Paulina Wang, Philip D. Stein, Andrew T. Pudzianowski, David W. Green, Hossain Monshizadegan, Karnail S. Atwal	2004	23
14	Lewis acid assisted condensations between a 5-methoxyisoxazolidine and silicon-based nucleophiles: .gamma.-amino alcohol building block in the synthesis of agroclavine I Journal of the American Chemical Society ·Alan P. Kozikowski, Philip D. Stein	1985	22
15	Aroylguanidine-based factor Xa inhibitors: The discovery of BMS-344577 Bioorganic & Medicinal Chemistry Letters ·Yan Shi, Chi Li, Stephen P. O’Connor, Jing Zhang, Mengxiao Shi, Sharon N. Bisaha, Ying Wang, Doree Sitkoff, Andrew T. Pudzianowski, Christine Huang, Herbert E. Klei, Kevin Kish, Joseph Yanchunas, Eddie C.‐K. Liu, Karen S. Hartl, Steve M. Seiler, Thomas E. Steinbacher, William A. Schumacher, Karnail S. Atwal, Philip D. Stein	2009	19
16	Enzymatic methods for the preparation of acetyl-CoA and analogs Bioorganic Chemistry ·Uta‐Maria Billhardt, Philip D. Stein, George M. Whitesides	1989	19
17	Design and Synthesis of 4-Substituted Benzamides as Potent, Selective, and Orally Bioavailable I_Ks Blockers Journal of Medicinal Chemistry ·John Lloyd, Joan B. Schmidt, George C. Rovnyak, Saleem Ahmad, Karnail S. Atwal, Sharon N. Bisaha, Lidia M. Doweyko, Philip D. Stein, Sarah C. Traeger, Arvind Mathur, Mary Lee Conder, John D. DiMarco, Timothy W. Harper, Tonya Jenkins-West, Paul Lévesque, Diane E. Normandin, Anita D. Russell, R Serafino, Mark A. Smith, Nicholas J. Lodge	2001	18
18	Mutational Analysis of the Endothelin Type A Receptor (ET_A): Interactions and Model of the Selective ET_AAntagonist BMS-182874 with the Putative ET_AReceptor Binding Cavity Biochemistry ·Maria L. Webb, Pramathesh S. Patel, Patricia M. Rose, Eddie C.‐K. Liu, Philip D. Stein, Joel C. Barrish, David A. Lach, Terry R. Stouch, Susan Fisher, Ophelia W. Hadjilambris, Helen Lee, Stephen Skwish, Kenneth E.J. Dickinson, Stanley R. Krystek	1996	17
19	Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors Bioorganic & Medicinal Chemistry Letters ·Yan Shi, Jing Zhang, Mengxiao Shi, Stephen P. O’Connor, Sharon N. Bisaha, Chi Li, Doree Sitkoff, Andrew T. Pudzianowski, Saeho Chong, Herbert E. Klei, Kevin Kish, Joseph Yanchunas, Eddie C.‐K. Liu, Karen S. Hartl, Steve M. Seiler, Thomas E. Steinbacher, William A. Schumacher, Karnail S. Atwal, Philip D. Stein	2009	13
20	Treatment of Clostridium difficile Infection with a Small-Molecule Inhibitor of Toxin UDP-Glucose Hydrolysis Activity Antimicrobial Agents and Chemotherapy ·Ilana L. Stroke, Jeffrey J. Letourneau, Teresa E. Miller, Yan Xu, Igor Pechik, Diana R. Savoly, Linh Ma, Laurie J. Sturzenbecker, Joan Sabalski, Philip D. Stein, Maria L. Webb, David W. Hilbert	2018	12

About Philip D. Stein

Philip D. Stein is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine, Physiology, Organic Chemistry and Hematology, having authored 44 papers that have together received 906 indexed citations. Recurring topics across this work include Nitric Oxide and Endothelin Effects (10 papers), Blood Coagulation and Thrombosis Mechanisms (6 papers), Receptor Mechanisms and Signaling (5 papers), Cardiac electrophysiology and arrhythmias (4 papers), ATP Synthase and ATPases Research (4 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (4 papers), Electron Spin Resonance Studies (4 papers) and Mitochondrial Function and Pathology (4 papers). The work is most often cited by research in Organic Chemistry (347 citations), Physiology (265 citations), Cardiology and Cardiovascular Medicine (194 citations), Biochemistry (51 citations) and Biophysics (40 citations). Philip D. Stein has collaborated with scholars based in United States, Germany and Sweden. Frequent co-authors include Alan P. Kozikowski, Eddie C.‐K. Liu, Suzanne Moreland, John T. Hunt, David Floyd, Patricia M. Rose, Maria L. Webb, Natesan Murugesan, Kenneth E.J. Dickinson and Sophie Beyer. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Cardiovascular Research, The Journal of Organic Chemistry and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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