Paul E. Finke

2.4k citations

45 papers · 1.7k · h-index 24

Impact in

Virology top 5%
Cancer Research top 10%
- Protease and Inhibitor Mechanisms

Papers in

Molecular Biology 16
- Receptor Mechanisms and Signaling 4
- Chemical Synthesis and Analysis 4
Organic Chemistry 15
- Synthesis of β-Lactam Compounds 10
- Carbohydrate Chemistry and Synthesis 4

Co-authors: James B. Doherty (20 shared papers)Bonnie M. Ashe (17 shared papers)Malcolm MacCoss (10 shared papers)Sander G. Mills (10 shared papers)Alan L. Maycock (17 shared papers)Shrenik K. Shah (15 shared papers)Ryan O'Neal (3 shared papers)Ki Taek Nam (4 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (13 papers)Journal of Medicinal Chemistry (4 papers)Biochemistry (4 papers)Nature (2 papers)Gut (2 papers)
Partner nations: United States United Kingdom South Korea

In The Last Decade

Paul E. Finke

45 papers receiving 1.6k citations

Peers

Countries citing papers authored by Paul E. Finke

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Citations

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Fields of papers citing papers by Paul E. Finke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul E. Finke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul E. Finke. The network helps show where Paul E. Finke may publish in the future.

Co-authors

The 25 scholars most cited alongside Paul E. Finke, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paul E. Finke Line = papers co-authored together Paul E. Finke links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 45 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Mature Chief Cells Are Cryptic Progenitors for Metaplasia in the Stomach Gastroenterology ·Ki Taek Nam, Hyuk–Joon Lee, Josane F. Sousa, Victoria G. Weis, Ryan O'Neal, Paul E. Finke, Judith Romero–Gallo, Guanglu Shi, Jason C. Mills, Richard M. Peek, Stephen F. Konieczny, James R. Goldenring	2010	231
2	Structural Optimization Affording 2-(R)-(1-(R)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist Journal of Medicinal Chemistry ·Jeffrey J. Hale, Sander G. Mills, Malcolm MacCoss, Paul E. Finke, Margaret A. Cascieri, Sharon Sadowski, Elżbieta Ber, Gary G. Chicchi, Marc M. Kurtz, Joseph M. Metzger, George J. Eiermann, Nancy N. Tsou, F.D. Tattersall, N.M.J. Rupniak, Angela Williams, Wayne Rycroft, Richard Hargreaves, D. Euan MacIntyre	1998	176
3	Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase Nature ·James B. Doherty, Bonnie M. Ashe, Lawrence W. Argenbright, Peter L. Barker, Robert J. Bonney, Gilbert O. Chandler, Mary Ellen Dahlgren, Conrad P. Dorn, Paul E. Finke, Raymond A. Firestone, Daniel S. Fletcher, William K. Hagmann, Richard A. Mumford, Laura O’Grady, Alan L. Maycock, Judith M. Pisano, Shrenik K. Shah, Kevan R. Thompson, Morris Zimmerman	1986	149
4	The novel NK1 receptor antagonist MK–0869 (L–754,030) and its water soluble phosphoryl prodrug, L–758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets Neuropharmacology ·F.D. Tattersall, Wayne Rycroft, M. Cumberbatch, G.S. Mason, Spencer J. Tye, David J. Williamson, J.J. Hale, Sander G. Mills, Paul E. Finke, Malcolm MacCoss, Sharon Sadowski, E Ber, Margaret A. Cascieri, R.G. Hill, D. Euan MacIntyre, Richard Hargreaves	2000	126
5	Crystallographie study of a β-lactam inhibitor complex with elastase at 1.84 Å resolution Nature ·Manuel A. Navia, James P. Springer, Tsau-Yen Lin, Hollis R. Williams, Raymond A. Firestone, Judith M. Pisano, James B. Doherty, Paul E. Finke, Karst Hoogsteen	1987	93
6	Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4: synthesis and structure–Activity relationships for 1-[N-(Methyl)-N-(phenylsulfonyl)amino]-2-(phenyl)-4-(4-(N-(alkyl)-N-(benzyloxycarbonyl)amino)piperidin-1-yl)butanes Bioorganic & Medicinal Chemistry Letters ·Paul E. Finke, Bryan Oates, Sander G. Mills, Malcolm MacCoss, Lorraine Malkowitz, Martin S. Springer, Sandra L. Gould, Julie A. DeMartino, Anthony Carella, Gwen Carver, Karen Holmes, Renee Danzeisen, Daria J. Hazuda, Joseph Kessler, Janet Lineberger, Michael D. Miller, William A. Schleif, Emilio A. Emini	2001	70
7	Binding of 2-Aryl-4-(piperidin-1-yl)butanamines and 1,3,4-Trisubstituted Pyrrolidines to Human CCR5: A Molecular Modeling-Guided Mutagenesis Study of the Binding Pocket Biochemistry ·Laurie A. Castonguay, Youmin Weng, William Adolfsen, Jerry Di Salvo, Ruth Kilburn, Charles G. Caldwell, Bruce L. Daugherty, Paul E. Finke, Jeffrey J. Hale, Christopher L. Lynch, Sander G. Mills, Malcolm MacCoss, Martin S. Springer, Julie A. DeMartino	2003	62
8	Synthesis and activity of 4,5-diarylimidazoles as human CB1 receptor inverse agonists Bioorganic & Medicinal Chemistry Letters ·Christopher W. Plummer, Paul E. Finke, Sander G. Mills, Junying Wang, Xinchun Tong, George A. Doss, Tung M. Fong, Julie Lao, Marie‐Therese Schaeffer, Jing Chen, Chun-Pyn Shen, D. Sloan Stribling, Lauren P. Shearman, Alison M. Strack, Lex H.T. Van der Ploeg	2005	52
9	Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol Journal of Medicinal Chemistry ·Paul E. Finke, Shrenik K. Shah, Bonnie M. Ashe, Richard G. Ball, Thomas J. Blacklock, Robert J. Bonney, Karen A. Brause, Gilbert O. Chandler, (unknown)	1992	49
10	The fibrinogen cleavage product A -Val360, a specific marker of neutrophil elastase activity in vivo Thorax ·Richard I. Carter, Richard A. Mumford, Kelly Treonze, Paul E. Finke, Philip R. Davies, Qin Si, John L. Humes, Asger Dirksen, Eeva Piitulainen, Arsalan Ahmad, Robert A. Stockley	2011	48
11	Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins Journal of Medicinal Chemistry ·S. K. Shah, Karen A. Brause, Gilbert O. Chandler, Paul E. Finke, Bonnie M. Ashe, Hazel Weston, Wilson B. Knight, Alan L. Maycock, James B. Doherty	1990	47
12	Spasmolytic polypeptide-expressing metaplasia (SPEM) in the gastric oxyntic mucosa does not arise from Lgr5-expressing cells Gut ·Ki Taek Nam, Ryan O'Neal, Robert J. Coffey, Paul E. Finke, Nick Barker, James R. Goldenring	2011	43
13	A Comparison of α1-Proteinase Inhibitor Methoxysuccinyl-Ala-Ala-Pro-Val-Chloromethylketone and Specific β-Lactam Inhibitors in an Acute Model of Human Polymorphonuclear Leukocyte Elastase-induced Lung Hemorrhage in the Hamster American Review of Respiratory Disease ·Daniel S. Fletcher, Donald G. Osinga, Karen M. Hand, Pam S. Dellea, Bonnie M. Ashe, Richard A. Mumford, Philip R. Davies, William K. Hagmann, Paul E. Finke, James B. Doherty, Robert J. Bonney	1990	42
14	Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives Biochemistry ·Wilson B. Knight, Alan L. Maycock, B. G. Green, Bonnie M. Ashe, Philip A. Gale, Hazel Weston, Paul E. Finke, W. K. HAGMANN, Shrenik K. Shah, James B. Doherty	1992	37
15	Cyclopentane-based human NK1 antagonists. Part 1: Discovery and initial SAR Bioorganic & Medicinal Chemistry Letters ·Paul E. Finke, Laura C. Meurer, Dorothy Levorse, Sander G. Mills, Malcolm MacCoss, Sharon Sadowski, Margaret A. Cascieri, Kwei‐Lan Tsao, Gary G. Chicchi, Joseph M. Metzger, D. Euan MacIntyre	2006	35
16	THE METABOLIC DISPOSITION OF APREPITANT, A SUBSTANCE P RECEPTOR ANTAGONIST, IN RATS AND DOGS Drug Metabolism and Disposition ·Su-Er W. Huskey, Brian J. Dean, George A. Doss, Zhen Wang, Cornelis E. C. A. Hop, Reza Anari, Paul E. Finke, Albert J. Robichaud, Minghua Zhang, Bonnie Wang, John R. Strauss, Paul Cunningham, William P. Feeney, Ronald B. Franklin, Thomas A. Baillie, Shuet-Hing Lee Chiu	2004	34
17	Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 3: A proposed pharmacophore model for 1-[N-(methyl)-N-(phenylsulfonyl)amino]-2-(phenyl)-4-[4-(substituted)piperidin-1-yl]butanes Bioorganic & Medicinal Chemistry Letters ·Paul E. Finke, Laura C. Meurer, Bryan Oates, Shrenik K. Shah, Jennifer L. Loebach, Sander G. Mills, Malcolm MacCoss, Laurie Castonguay, Lorraine Malkowitz, Martin S. Springer, Sandra L. Gould, Julie A. DeMartino	2001	33
18	PMN elastases: A comparison of the specificity of human isozymes and the enzyme from other species toward substrates and inhibitors Archives of Biochemistry and Biophysics ·B.G. Green, Hazel Weston, Bonnie M. Ashe, James B. Doherty, Paul E. Finke, W. K. HAGMANN, Michael W. Lark, JENNIFER MAO, Alan L. Maycock, Vernon L. Moore, Richard A. Mumford, Samir K. Shah, Lori A. Walakovits, Wilson B. Knight	1991	32
19	Synthesis and SAR of 5,6-diarylpyridines as human CB1 inverse agonists Bioorganic & Medicinal Chemistry Letters ·Laura C. Meurer, Paul E. Finke, Sander G. Mills, Thomas F. Walsh, Richard B. Toupence, Mark T. Goulet, Junying Wang, Xinchun Tong, Tung M. Fong, Julie Lao, Marie‐Therese Schaeffer, Jing Chen, Chun-Pyn Shen, D. Sloan Stribling, Lauren P. Shearman, Alison M. Strack, Lex H.T. Van der Ploeg	2004	30
20	Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase. Proceedings of the National Academy of Sciences ·James B. Doherty, S. K. Shah, Paul E. Finke, Conrad P. Dorn, W. K. HAGMANN, Jeffrey J. Hale, A L Kissinger, Kevan R. Thompson, Karen A. Brause, Gilbert O. Chandler	1993	30

About Paul E. Finke

Paul E. Finke is a scholar working on Molecular Biology, Organic Chemistry, Oncology, Cancer Research and Cellular and Molecular Neuroscience, having authored 45 papers that have together received 1.7k indexed citations. Recurring topics across this work include Synthesis of β-Lactam Compounds (10 papers), Protease and Inhibitor Mechanisms (7 papers), Peptidase Inhibition and Analysis (5 papers), Cell Adhesion Molecules Research (5 papers), Receptor Mechanisms and Signaling (4 papers), Carbohydrate Chemistry and Synthesis (4 papers), Chemical Synthesis and Analysis (4 papers) and Neuropeptides and Animal Physiology (4 papers). The work is most often cited by research in Virology (91 citations), Cancer Research (253 citations), Organic Chemistry (496 citations), Oncology (372 citations) and Immunology and Allergy (81 citations). Paul E. Finke has collaborated with scholars based in United States, United Kingdom and South Korea. Frequent co-authors include James B. Doherty, Bonnie M. Ashe, Malcolm MacCoss, Sander G. Mills, Alan L. Maycock, Shrenik K. Shah, Ryan O'Neal, Ki Taek Nam, James R. Goldenring and Richard A. Mumford. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Biochemistry, Nature and Gut.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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