George J. Eiermann

5.0k citations

30 papers · 1.5k · h-index 23

Impact in

Endocrinology, Diabetes and Metabolism top 2%
- Diabetes Treatment and Management
Cellular and Molecular Neuroscience top 5%
- Neuropeptides and Animal Physiology

Papers in

Cellular and Molecular Neuroscience 19
- Neuropeptides and Animal Physiology 18
Endocrinology, Diabetes and Metabolism 19
- Diabetes Treatment and Management 19

Co-authors: Nancy A. Thornberry (18 shared papers)Aleksandr Petrov (17 shared papers)Joseph K. Wu (16 shared papers)Ann E. Weber (16 shared papers)Huaibing He (14 shared papers)Ranabir SinhaRoy (7 shared papers)Gary G. Chicchi (3 shared papers)Barbara Leiting (11 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (16 papers)Assay and Drug Development Technologies (1 paper)Journal of Pharmacology and Experimental Therapeutics (1 paper)BMC Immunology (1 paper)Bioorganic & Medicinal Chemistry (1 paper)
Partner nations: United States United Kingdom Italy

In The Last Decade

George J. Eiermann

30 papers receiving 1.4k citations

Peers

Countries citing papers authored by George J. Eiermann

Since Specialization

Citations

This map shows the geographic impact of George J. Eiermann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by George J. Eiermann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites George J. Eiermann more than expected).

Fields of papers citing papers by George J. Eiermann

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by George J. Eiermann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by George J. Eiermann. The network helps show where George J. Eiermann may publish in the future.

Co-authors

The 25 scholars most cited alongside George J. Eiermann, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with George J. Eiermann Line = papers co-authored together George J. Eiermann links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 30 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Structural Optimization Affording 2-(R)-(1-(R)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist Journal of Medicinal Chemistry ·Jeffrey J. Hale, Sander G. Mills, Malcolm MacCoss, Paul E. Finke, Margaret A. Cascieri, Sharon Sadowski, Elżbieta Ber, Gary G. Chicchi, Marc M. Kurtz, Joseph M. Metzger, George J. Eiermann, Nancy N. Tsou, F.D. Tattersall, N.M.J. Rupniak, Angela Williams, Wayne Rycroft, Richard Hargreaves, D. Euan MacIntyre	1998	176
2	Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice Diabetes ·Carina P. Tan, Yue Feng, Yun-Ping Zhou, George J. Eiermann, Aleksandr Petrov, Changyou Zhou, Songnian Lin, Gino Salituro, Peter T. Meinke, Ralph Mosley, Taro E. Akiyama, Monica Einstein, Sanjeev Kumar, Joel P. Berger, Sander G. Mills, Nancy A. Thornberry, Lihu Yang, Andrew D. Howard	2008	139
3	Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes European Journal of Pharmacology ·James Mu, Aleksandr Petrov, George J. Eiermann, John Woods, Yun-Ping Zhou, Zhihua Li, Emanuel Zycband, Yue Feng, Lan Zhu, Ranabir Sinha Roy, Andrew D. Howard, Li Cai, Nancy A. Thornberry, Bei B. Zhang	2009	122
4	Optimization of co‐agonism at GLP‐1 and glucagon receptors to safely maximize weight reduction in DIO‐rodents Biopolymers ·Jonathan W. Day, Vasily M. Gelfanov, David L. Smiley, Paul E. Carrington, George J. Eiermann, Gary G. Chicchi, Mark D. Erion, Jas Gidda, Nancy A. Thornberry, Matthias H. Tschöp, Donald J. Marsh, Ranabir SinhaRoy, Richard D. DiMarchi, Alessandro Pocai	2012	115
5	A comparative study of the binding properties, dipeptidyl peptidase‐4 (DPP‐4) inhibitory activity and glucose‐lowering efficacy of the DPP‐4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in mice Endocrinology Diabetes & Metabolism ·Joel P. Berger, Ranabir SinhaRoy, Alessandro Pocai, Theresa M. Kelly, Giovanna Scapin, Ying‐Duo Gao, Kelly Ann D. Pryor, Joseph K. Wu, George J. Eiermann, Shiyao Xu, Xiaoping Zhang, Daniel Tatosian, Ann E. Weber, Nancy A. Thornberry, Richard D. Carr	2017	75
6	The Role of Voltage-Gated Potassium Channels Kv2.1 and Kv2.2 in the Regulation of Insulin and Somatostatin Release from Pancreatic Islets Journal of Pharmacology and Experimental Therapeutics ·Xiaoyan Li, James Herrington, Aleksandr Petrov, Lan Ge, George J. Eiermann, Yusheng Xiong, Mette V. Jensen, Hans E. Hohmeier, Christopher B. Newgard, María L. García, Michael Wagner, Bei B. Zhang, Nancy A. Thornberry, Andrew D. Howard, Gregory J. Kaczorowski, Yun-Ping Zhou	2012	62
7	Recombinant human interleukin‐1 β–induced increase in levels of proteoglycans, stromelysin, and leukocytes in rabbit synovial fluid Arthritis & Rheumatism ·Joseph McDonnell, Lori A. Hoerrner, Michael W. Lark, Coral Harper, Tanvi Dey, Julie M. Lobner, George J. Eiermann, D M Kazazis, Irwin Singer, Vernon L. Moore	1992	62
8	Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin Bioorganic & Medicinal Chemistry Letters ·Tesfaye Biftu, Giovanna Scapin, Suresh B. Singh, Dennis Feng, Joe W. Becker, George J. Eiermann, Huaibing He, Kathy Lyons, Sangita B. Patel, Aleksandr Petrov, Ranabir SinhaRoy, Bei Zhang, Joseph K. Wu, Xiaoping Zhang, George A. Doss, Nancy A. Thornberry, Ann E. Weber	2007	57
9	Polymorphonuclear leukocyte participation in acute oleic-acid-induced lung injury. PubMed ·George J. Eiermann, Burton F. Dickey, Roger S. Thrall	1983	52
10	Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Charles G. Caldwell, Ping Chen, Jiafang He, Emma R. Parmee, Barbara Leiting, Frank Marsilio, Reshma A. Patel, Joseph K. Wu, George J. Eiermann, Aleksandr Petrov, Huaibing He, Kathryn A. Lyons, Nancy A. Thornberry, Ann E. Weber	2004	47
11	Differential effects of oxyntomodulin and GLP-1 on glucose metabolism American Journal of Physiology-Endocrinology and Metabolism ·Xiaobing Du, Jennifer Kosinski, Julie Lao, Xiaolan Shen, Aleksandr Petrov, Gary G. Chicchi, George J. Eiermann, Alessandro Pocai	2012	46
12	Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses BMC Immunology ·Kalpit A. Vora, Gene Porter, Roche Peng, Yan Cui, KellyAnn D. Pryor, George J. Eiermann, Dennis M. Zaller	2009	43
13	Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA™ (sitagliptin phosphate) Bioorganic & Medicinal Chemistry Letters ·Dooseop Kim, Jennifer E. Kowalchick, Scott D. Edmondson, Anthony Mastracchio, Jinyou Xu, George J. Eiermann, Barbara Leiting, Joseph K. Wu, KellyAnn D. Pryor, Reshma A. Patel, Huaibing He, Kathryn A. Lyons, Nancy A. Thornberry, Ann E. Weber	2007	42
14	A PEGylated analog of the gut hormone oxyntomodulin with long-lasting antihyperglycemic, insulinotropic and anorexigenic activity Bioorganic & Medicinal Chemistry ·Elisabetta Bianchi, Paul E. Carrington, Paolo Ingallinella, Marco Finotto, Alessia Santoprete, Aleksandr Petrov, George J. Eiermann, Jennifer Kosinski, Donald J. Marsh, Alessandro Pocai, Ranabir SinhaRoy, Antonello Pessi	2013	40
15	Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Scott D. Edmondson, Anthony Mastracchio, Jason M. Cox, George J. Eiermann, Huaibing He, Kathryn A. Lyons, Reshma A. Patel, Sangita B. Patel, Aleksandr Petrov, Giovanna Scapin, Joseph K. Wu, Shiyao Xu, Bing Zhu, Nancy A. Thornberry, Ranabir Sinha Roy, Ann E. Weber	2009	38
16	(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Bioorganic & Medicinal Chemistry Letters ·Tesfaye Biftu, Dennis Feng, Xiaoxia Qian, Gui‐Bai Liang, G. R. KIECZYKOWSKI, George J. Eiermann, Huaibing He, Barbara Leiting, Kathy Lyons, Aleksandr Petrov, Ranabir SinhaRoy, Bei Zhang, Giovanna Scapin, Sangita Patel, Ying‐Duo Gao, Suresh B. Singh, Joseph K. Wu, Xiaoping Zhang, Nancy A. Thornberry, Ann E. Weber	2006	38
17	Discovery of potent and selective orally bioavailable β-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Scott D. Edmondson, Anthony Mastracchio, Joseph Duffy, George J. Eiermann, Huaibing He, Ida E. Ita, Barbara Leiting, Joseph F. Leone, Kathryn A. Lyons, Amanda M. Makarewicz, Reshma A. Patel, Aleksandr Petrov, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber	2005	38
18	4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Emma R. Parmee, Jiafang He, Anthony Mastracchio, Scott D. Edmondson, Larry Colwell, George J. Eiermann, William P. Feeney, Bahanu Habulihaz, Huaibing He, Ruth Kilburn, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Reshma A. Patel, Aleksandr Petrov, Jerry Di Salvo, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber	2003	37
19	Design, synthesis, and biological evaluation of triazolopiperazine-based β-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors Bioorganic & Medicinal Chemistry Letters ·Jennifer E. Kowalchick, Barbara Leiting, KellyAnn D. Pryor, Frank Marsilio, Joseph K. Wu, Huaibing He, Kathryn A. Lyons, George J. Eiermann, Aleksandr Petrov, Giovanna Scapin, Reshma A. Patel, Nancy A. Thornberry, Ann E. Weber, Dooseop Kim	2007	34
20	Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: Profile of clinical candidate (2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine (23) Bioorganic & Medicinal Chemistry Letters ·Tesfaye Biftu, Xiaoxia Qian, Ping Chen, Dennis Feng, Giovanna Scapin, Ying‐Duo Gao, Jason M. Cox, Ranabir Sinha Roy, George J. Eiermann, Huabing He, Kathy Lyons, Gino Salituro, Sangita B. Patel, Alexander Petrov, Feng Xu, Shiyao Xu, Bei Zhang, Charles G. Caldwell, Joseph K. Wu, Ann E. Weber	2013	32

About George J. Eiermann

George J. Eiermann is a scholar working on Cellular and Molecular Neuroscience, Endocrinology, Diabetes and Metabolism, Oncology, Molecular Biology and Surgery, having authored 30 papers that have together received 1.5k indexed citations. Recurring topics across this work include Diabetes Treatment and Management (19 papers), Neuropeptides and Animal Physiology (18 papers), Peptidase Inhibition and Analysis (16 papers), Pancreatic function and diabetes (4 papers), Receptor Mechanisms and Signaling (3 papers), Cardiac electrophysiology and arrhythmias (2 papers), Ion channel regulation and function (2 papers) and Metabolism, Diabetes, and Cancer (2 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (624 citations), Cellular and Molecular Neuroscience (389 citations), Oncology (362 citations), Endocrine and Autonomic Systems (66 citations) and Pharmaceutical Science (57 citations). George J. Eiermann has collaborated with scholars based in United States, United Kingdom and Italy. Frequent co-authors include Nancy A. Thornberry, Aleksandr Petrov, Joseph K. Wu, Ann E. Weber, Huaibing He, Ranabir SinhaRoy, Gary G. Chicchi, Barbara Leiting, Kathryn A. Lyons and Alessandro Pocai. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Assay and Drug Development Technologies, Journal of Pharmacology and Experimental Therapeutics, BMC Immunology and Bioorganic & Medicinal Chemistry.

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