Paul Dent

29.1k citations

388 papers · 23.1k · 4 hit papers · h-index 81

Impact in

Oncology top 0.2%
- Cancer-related Molecular Pathways
Molecular Biology top 0.1%
- Cell death mechanisms and regulation
- Protein Kinase Regulation and GTPase Signaling
- Histone Deacetylase Inhibitors Research
- Melanoma and MAPK Pathways
- PI3K/AKT/mTOR signaling in cancer

Papers in

Molecular Biology 299
- Cell death mechanisms and regulation 75
- Histone Deacetylase Inhibitors Research 62
- Melanoma and MAPK Pathways 49
- Protein Kinase Regulation and GTPase Signaling 45
- PI3K/AKT/mTOR signaling in cancer 34
Oncology 122
- Cancer-related Molecular Pathways 52

Co-authors: Steven Grant (167 shared papers)Mohamed Rahmani (50 shared papers)Paul B. Fisher (77 shared papers)Thomas W. Sturgill (20 shared papers)Adly Yacoub (62 shared papers)Yun Dai (50 shared papers)Kristoffer Valerie (27 shared papers)Laurence Booth (86 shared papers)
Journals: Cancer Biology & Therapy (41 papers)Molecular Pharmacology (33 papers)Blood (23 papers)Oncogene (20 papers)Cancer Research (19 papers)
Partner nations: United States Russia Canada

In The Last Decade

Paul Dent

387 papers receiving 22.8k citations

Paul Dent's Hit Papers

align trajectories log scale

Bile acids as regulatory molecules 2009 · 562 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2009 Journal of Lipid Research
2003 Oncogene
1993 Science
1992 Science

Peers

Countries citing papers authored by Paul Dent

Since Specialization

Citations

This map shows the geographic impact of Paul Dent's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul Dent with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul Dent more than expected).

Fields of papers citing papers by Paul Dent

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul Dent. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul Dent. The network helps show where Paul Dent may publish in the future.

Co-authors

The 25 scholars most cited alongside Paul Dent, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paul Dent Line = papers co-authored together Paul Dent links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 388 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate Science ·Jie Wu, Paul Dent, Tomáš Jelı́nek, Alan Wolfman, Michael J. Weber, Thomas W. Sturgill Hit paper breakdown →	1993	824
2	Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and in Vitro Science ·Paul Dent, W G Haser, Timothy Haystead, L A Vincent, Thomas M. Roberts, Thomas W. Sturgill Hit paper breakdown →	1992	603
3	Bile acids as regulatory molecules Journal of Lipid Research ·Phillip B. Hylemon, Huiping Zhou, William M. Pandak, Shunlin Ren, Gregorio Gil, Paul Dent Hit paper breakdown →	2009	562
4	MAPK pathways in radiation responses Oncogene ·Paul Dent, Adly Yacoub, Paul B. Fisher, Michael P. Hagan, Steven Grant Hit paper breakdown →	2003	523
5	The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle Nature ·Paul Dent, Alain Lavoinne, Sara Nakielny, F. Barry Caudwell, Peter Watt, Philip Cohen	1990	437
6	Stress and Radiation-Induced Activation of Multiple Intracellular Signaling Pathways¹ Radiation Research ·Paul Dent, Adly Yacoub, Joseph N. Contessa, Rubén W. Carón, George P. Amorino, Kristoffer Valerie, Michael P. Hagan, Steven Grant, Rupert Schmidt‐Ullrich	2003	391
7	Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation Oncogene ·Rupert Schmidt‐Ullrich, Ross B. Mikkelsen, Paul Dent, Daniel G. Todd, Kristoffer Valerie, Brian D. Kavanagh, Joseph N. Contessa, William K Rorrer, P B Chen	1997	343
8	Mcl-1 Down-regulation Potentiates ABT-737 Lethality by Cooperatively Inducing Bak Activation and Bax Translocation Cancer Research ·Shuang Chen, Yun Dai, Hisashi Harada, Paul Dent, Steven Grant	2007	317
9	The role of cell signalling in the crosstalk between autophagy and apoptosis Cellular Signalling ·Laurence Booth, Seyedmehrad Tavallai, Hossein A. Hamed, Nichola Cruickshanks, Paul Dent	2013	287
10	Radiation-induced Release of Transforming Growth Factor α Activates the Epidermal Growth Factor Receptor and Mitogen-activated Protein Kinase Pathway in Carcinoma Cells, Leading to Increased Proliferation and Protection from Radiation-induced Cell Death Molecular Biology of the Cell ·Paul Dent, Dean B. Reardon, Jong Sung Park, Geoffrey Bowers, Craig D. Logsdon, Kristoffer Valerie, Rupert Schmidt‐Ullrich	1999	279
11	Radiation-induced cell signaling: inside-out and outside-in Molecular Cancer Therapeutics ·Kristoffer Valerie, Adly Yacoub, Michael P. Hagan, David T. Curiel, Paul B. Fisher, Steven Grant, Paul Dent	2007	263
12	Signal Transduction and Cellular Radiation Responses Radiation Research ·Rupert Schmidt‐Ullrich, Paul Dent, Steven Grant, Ross B. Mikkelsen, Kristoffer Valerie	2000	259
13	Conjugated Bile Acids Activate the Sphingosine–1–Phosphate Receptor 2 in Primary Rodent Hepatocytes Hepatology ·Elaine Studer, Xiqiao Zhou, Renping Zhao, Yun Wang, Kazuaki Takabe, Masayuki Nagahashi, William M. Pandak, Paul Dent, Sarah Spiegel, Ruihua Shi, Weiren Xu, Xuyuan Liu, Pat Bohdan, Luyong Zhang, Huiping Zhou, Phillip B. Hylemon	2011	250
14	Apoptosis Induced by the Kinase Inhibitor BAY 43-9006 in Human Leukemia Cells Involves Down-regulation of Mcl-1 through Inhibition of Translation Journal of Biological Chemistry ·Mohamed Rahmani, Eric Maynard Davis, Cheryl Bauer, Paul Dent, Steven Grant	2005	243
15	Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance Cancer Research ·Nathan T. Ihle, Robert Lemos, Peter Wipf, Adly Yacoub, Clint Mitchell, Doris R. Siwak, Gordon B. Mills, Paul Dent, D. Lynn Kirkpatrick, Garth Powis	2008	225
16	The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571 Blood ·Chunrong Yu, Mohamed Rahmani, Daniel H. Conrad, Mark A. Subler, Paul Dent, Steven Grant	2003	220
17	Targeting the Bcl-2 family for cancer therapy Expert Opinion on Therapeutic Targets ·Shibu Thomas, Bridget A. Quinn, Swadesh K. Das, Rupesh Dash, Luni Emdad, Santanu Dasgupta, Xiang‐Yang Wang, Paul Dent, John C. Reed, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher	2012	218
18	zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro. The EMBO Journal ·María T. Díaz‐Meco, Isabel Domínguez, Laura Sanz, Paul Dent, José Lozano, M.M. Municio, Edurne Berra, Ronald T. Hay, Thomas W. Sturgill, Jorge Moscat	1994	211
19	Blockade of Histone Deacetylase Inhibitor-Induced RelA/p65 Acetylation and NF-κB Activation Potentiates Apoptosis in Leukemia Cells through a Process Mediated by Oxidative Damage, XIAP Downregulation, and c-Jun N-Terminal Kinase 1 Activation Molecular and Cellular Biology ·Yun Dai, Mohamed Rahmani, Paul Dent, Steven Grant	2005	205
20	The Kinase Inhibitor Sorafenib Induces Cell Death through a Process Involving Induction of Endoplasmic Reticulum Stress Molecular and Cellular Biology ·Mohamed Rahmani, Eric Maynard Davis, Timothy Ryan Crabtree, Joseph Habibi, Tri K. Nguyen, Paul Dent, Steven Grant	2007	198

About Paul Dent

Paul Dent is a scholar working on Molecular Biology, Oncology, Cell Biology, Epidemiology and Hematology, having authored 388 papers that have together received 23.1k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (75 papers), Histone Deacetylase Inhibitors Research (62 papers), Autophagy in Disease and Therapy (55 papers), Cancer-related Molecular Pathways (52 papers), Melanoma and MAPK Pathways (49 papers), Protein Kinase Regulation and GTPase Signaling (45 papers), Endoplasmic Reticulum Stress and Disease (37 papers) and PI3K/AKT/mTOR signaling in cancer (34 papers). The work is most often cited by research in Oncology (7.0k citations), Molecular Biology (15.6k citations), Cell Biology (2.8k citations), Cancer Research (2.4k citations) and Hematology (1.6k citations). Paul Dent has collaborated with scholars based in United States, Russia and Canada. Frequent co-authors include Steven Grant, Mohamed Rahmani, Paul B. Fisher, Thomas W. Sturgill, Adly Yacoub, Yun Dai, Kristoffer Valerie, Laurence Booth, Rupert Schmidt‐Ullrich and Michael P. Hagan. Their work appears in journals such as Cancer Biology & Therapy, Molecular Pharmacology, Blood, Oncogene and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Paul Dent's Hit Papers

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About Paul Dent

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