Luke E. Springer

1.1k citations

23 papers · 764 · h-index 12

Impact in

Rheumatology top 5%
- Osteoarthritis Treatment and Mechanisms
- Rheumatoid Arthritis Research and Therapies
Immunology top 10%
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune cells in cancer

Papers in

Immunology 10
- Galectins and Cancer Biology 3
Molecular Biology 6
- RNA Interference and Gene Delivery 3

Co-authors: Christine T. N. Pham (16 shared papers)Antonina Akk (8 shared papers)Ying Hu (5 shared papers)Huimin Yan (5 shared papers)Samuel A. Wickline (6 shared papers)Huifang Zhou (3 shared papers)Huimin Yan (4 shared papers)Christine T. N. Pham (2 shared papers)
Journals: Proceedings of the National Academy of Sciences (3 papers)Science Advances (2 papers)Arthritis Research & Therapy (2 papers)Cellular and Molecular Immunology (1 paper)Frontiers in Immunology (1 paper)
Partner nations: United States South Korea Chile

In The Last Decade

Luke E. Springer

22 papers receiving 763 citations

Peers

Countries citing papers authored by Luke E. Springer

Since Specialization

Citations

This map shows the geographic impact of Luke E. Springer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Luke E. Springer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Luke E. Springer more than expected).

Fields of papers citing papers by Luke E. Springer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Luke E. Springer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Luke E. Springer. The network helps show where Luke E. Springer may publish in the future.

Co-authors

The 25 scholars most cited alongside Luke E. Springer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Luke E. Springer Line = papers co-authored together Luke E. Springer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Adipose tissue is a critical regulator of osteoarthritis Proceedings of the National Academy of Sciences ·Kelsey H. Collins, Kristin L. Lenz, Eleanor N. Pollitt, Daniel Ferguson, Irina Hutson, Luke E. Springer, Arin K. Oestreich, Ruhang Tang, Yun‐Rak Choi, Gretchen A. Meyer, Steven L. Teitelbaum, Christine T. N. Pham, Charles Harris, Farshid Guilak	2020	127
2	Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury Proceedings of the National Academy of Sciences ·Huimin Yan, Xin Duan, Hua Pan, Nilsson Holguin, Muhammad Farooq, Antonina Akk, Luke E. Springer, Samuel A. Wickline, Linda J. Sandell, Christine T. N. Pham	2016	117
3	Neutrophil Proteases Promote Experimental Abdominal Aortic Aneurysm via Extracellular Trap Release and Plasmacytoid Dendritic Cell Activation Arteriosclerosis Thrombosis and Vascular Biology ·Huimin Yan, Huifang Zhou, Antonina Akk, Ying Hu, Luke E. Springer, Terri L. Ennis, Christine T. N. Pham	2016	96
4	Fumagillin Prodrug Nanotherapy Suppresses Macrophage Inflammatory Response via Endothelial Nitric Oxide ACS Nano ·Hui-Fang Zhou, Huimin Yan, Ying Hu, Luke E. Springer, Xiaoxia Yang, Samuel A. Wickline, Dipanjan Pan, Gregory M. Lanza, Christine T. N. Pham	2014	88
5	Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis Journal of Clinical Investigation ·Hui-Fang Zhou, Huimin Yan, Hua Pan, Kirk K. Hou, Antonina Akk, Luke E. Springer, Ying Hu, John S. Allen, Samuel A. Wickline, Christine T. N. Pham	2014	82
6	CD43-Mediated IFN-γ Production by CD8+ T Cells Promotes Abdominal Aortic Aneurysm in Mice The Journal of Immunology ·Huifang Zhou, Huimin Yan, Judy L. Cannon, Luke E. Springer, Jonathan M. Green, Christine T. N. Pham	2013	56
7	Fibrinogen-specific antibody induces abdominal aortic aneurysm in mice through complement lectin pathway activation Proceedings of the National Academy of Sciences ·Huifang Zhou, Huimin Yan, Paula Bertram, Ying Hu, Luke E. Springer, Robert W. Thompson, John A. Curci, Dennis E. Hourcade, Christine T. N. Pham	2013	38
8	A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery Science Advances ·Yun‐Rak Choi, Kelsey H. Collins, Luke E. Springer, Lara Pferdehirt, Alison K. Ross, Chia‐Lung Wu, Franklin T. Moutos, Natalia S. Harasymowicz, Jonathan M. Brunger, Christine T. N. Pham, Farshid Guilak	2021	32
9	Neutrophil Extracellular Traps Enhance Early Inflammatory Response in Sendai Virus-Induced Asthma Phenotype Frontiers in Immunology ·Antonina Akk, Luke E. Springer, Christine T. N. Pham	2016	28
10	Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice International Journal of Nanomedicine ·Hua Pan, Rohun U Palekar, Kirk K. Hou, John Bacon, Huimin Yan, Luke E. Springer, Antonina Akk, Lihua Yang, Mark J. Miller, Christine T. N. Pham, Paul H. Schlesinger, Samuel A. Wickline	2018	24
11	Complement activation on neutrophils initiates endothelial adhesion and extravasation Molecular Immunology ·Antonina Akk, Luke E. Springer, Lihua Yang, Samantha Hamilton-Burdess, John D. Lambris, Huimin Yan, Ying Hu, Xiaobo Wu, Dennis E. Hourcade, Mark J. Miller, Christine T. N. Pham	2019	19
12	Clinicomolecular Identification of Conserved and Individualized Features of Granulomatous Uveitis SHILAP Revista de lepidopterología ·Lynn M. Hassman, Michael Paley, Ekaterina Esaulova, Grace Paley, Philip A. Ruzycki, Nicole Linskey, Jennifer Laurent, Lacey Feigl‐Lenzen, Luke E. Springer, Cynthia L. Montana, Karen Hong, Jennifer M. Enright, Hayley R. James, Maxim N. Artyomov, Wayne M. Yokoyama	2021	11
13	Hydrogel Encapsulation of Genome-Engineered Stem Cells for Long-Term Self-Regulating Anti-Cytokine Therapy Gels ·Kelsey H. Collins, Lara Pferdehirt, Leila Saleh, Alireza Savadipour, Luke E. Springer, Kristin L. Lenz, Dominic M. Thompson, Sara J. Oswald, Christine T. N. Pham, Farshid Guilak	2023	10
14	Safety Profile of Rapamycin Perfluorocarbon Nanoparticles for Preventing Cisplatin-Induced Kidney Injury Nanomaterials ·Qingyu Zhou, Justin Doherty, Antonina Akk, Luke E. Springer, Fan Ping, Ivan Spasojević, Ganesh V. Halade, Huanghe Yang, Christine T. N. Pham, Samuel A. Wickline, Hua Pan	2022	9
15	Adipose-derived leptin and complement factor D mediate osteoarthritis severity and pain Science Advances ·Kelsey H. Collins, Kristin L. Lenz, Hope D. Welhaven, Erica V. Ely, Luke E. Springer, Sophie G. Paradi, Ruhang Tang, Lauryn Braxton, Antonina Akk, Huimin Yan, Bo Zhang, Xiaobo Wu, John P. Atkinson, Arin K. Oestreich, Ronald K. June, Christine T. N. Pham, Farshid Guilak	2025	7
16	Nanotherapy Targeting NF-kB Attenuates Acute Pain After Joint Injury SHILAP Revista de lepidopterología ·Huimin Yan, Xin Duan, Kelsey H. Collins, Luke E. Springer, Farshid Guilak, Samuel A. Wickline, Mohamed Farook, Hua Pan, Christine T. N. Pham	2019	5
17	Engineered self-regulating macrophages for targeted anti-inflammatory drug delivery Arthritis Research & Therapy ·Molly Klimak, Amanda Cimino, Kristin L. Lenz, Luke E. Springer, Kelsey H. Collins, Natalia S. Harasymowicz, Nathan Xu, Christine T. N. Pham, Farshid Guilak	2024	5
18	Side-chain modification of collagen-targeting peptide prevents dye aggregation for improved molecular imaging of arthritic joints Journal of Photochemistry and Photobiology A Chemistry ·Megan S. Michie, Baogang Xu, Gail Sudlow, Luke E. Springer, Christine T. N. Pham, Samuel Achilefu	2021	4
19	Non-invasive monitoring of arthritis treatment response via targeting of tyrosine-phosphorylated annexin A2 in chondrocytes Arthritis Research & Therapy ·Shaw-Wei D Tsen, Luke E. Springer, Krishna Sharmah Gautam, Rui Tang, Kexian Liang, Gail Sudlow, Amir N. Kucharski, Christine T. N. Pham, Samuel Achilefu	2021	2
20	Accuracy and precision of point-of-care testing for serum cholesterol, triglycerides and HDL cholesterol Atherosclerosis ·Jeetesh V. Patel, G. H. G. Thorpe, Luke E. Springer, Elizabeth Hughes	2011	2

About Luke E. Springer

Luke E. Springer is a scholar working on Immunology, Molecular Biology, Epidemiology, Rheumatology and Pulmonary and Respiratory Medicine, having authored 23 papers that have together received 764 indexed citations. Recurring topics across this work include Osteoarthritis Treatment and Mechanisms (5 papers), Adipokines, Inflammation, and Metabolic Diseases (4 papers), Galectins and Cancer Biology (3 papers), Adipose Tissue and Metabolism (3 papers), Aortic aneurysm repair treatments (3 papers), RNA Interference and Gene Delivery (3 papers), NF-κB Signaling Pathways (3 papers) and Antimicrobial Peptides and Activities (3 papers). The work is most often cited by research in Rheumatology (224 citations), Immunology (228 citations), Cancer Research (77 citations), Immunology and Allergy (26 citations) and Pulmonary and Respiratory Medicine (139 citations). Luke E. Springer has collaborated with scholars based in United States, South Korea and Chile. Frequent co-authors include Christine T. N. Pham, Antonina Akk, Ying Hu, Huimin Yan, Samuel A. Wickline, Huifang Zhou, Huimin Yan, Christine T. N. Pham, Hua Pan and Kelsey H. Collins. Their work appears in journals such as Proceedings of the National Academy of Sciences, Science Advances, Arthritis Research & Therapy, Cellular and Molecular Immunology and Frontiers in Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Luke E. Springer

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