Kyle A. Emmitte

3.2k citations
70 papers · 2.2k · h-index 30

Impact in

Papers in

  • Molecular Biology 50
    • Receptor Mechanisms and Signaling 24
    • Ion channel regulation and function 10
    • Chemical Synthesis and Analysis 9
    • Pharmacological Receptor Mechanisms and Effects 9
    • Nicotinic Acetylcholine Receptors Study 5
  • Cellular and Molecular Neuroscience 44
    • Neuroscience and Neuropharmacology Research 41
Co-authors
Craig W. Lindsley (37 shared papers)Michael T. Crimmins (8 shared papers)P. Jeffrey Conn (33 shared papers)Colleen M. Niswender (26 shared papers)Corey R. Hopkins (3 shared papers)Alice L. Rodriguez (23 shared papers)Andrew S. Felts (22 shared papers)Karen J. Gregory (5 shared papers)
Journals
Bioorganic & Medicinal Chemistry Letters (14 papers)Journal of Medicinal Chemistry (8 papers)ACS Chemical Neuroscience (7 papers)Expert Opinion on Therapeutic Patents (4 papers)Organic Letters (4 papers)
Partner nations
United StatesAustraliaUnited Kingdom

In The Last Decade

Kyle A. Emmitte

66 papers receiving 2.2k citations

Peers

Kyle A. Emmitte
Comparison fields: 5 of 91
  • Cellular and Molecular Neuroscience 985
  • Biological Psychiatry 58
  • Molecular Biology 1.4k
  • Organic Chemistry 558
  • Toxicology 48
Replace Frédéric Bihel with:
Frédéric Bihel France
Richard W. Ransom United States
Youseung Shin United States
Corey R. Hopkins United States
Aloke K. Dutta United States
Norio Kaneda Japan
Stephen P. Andrews United Kingdom
Anna Katrin Szardenings United States
Michael R. Wood United States
Eric Vieira Switzerland
Kyle A. Emmitte relative to Frédéric Bihel France Frédéric Bihel's profile →
Citations per field
00.5×2×3.4×
Frédéric Bihel · 1×
Citations per year

Countries citing papers authored by Kyle A. Emmitte

Since Specialization
Citations

This map shows the geographic impact of Kyle A. Emmitte's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kyle A. Emmitte with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kyle A. Emmitte more than expected).

Fields of papers citing papers by Kyle A. Emmitte

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kyle A. Emmitte. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kyle A. Emmitte. The network helps show where Kyle A. Emmitte may publish in the future.

Co-authors

The 25 scholars most cited alongside Kyle A. Emmitte, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kyle A. Emmitte Line = papers co-authored together Kyle A. Emmitte links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 70 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery
Journal of Medicinal Chemistry ·Bruce J. Melancon, Corey R. Hopkins, Michael R. Wood, Kyle A. Emmitte, Colleen M. Niswender, Arthur Christopoulos, P. Jeffrey Conn, Craig W. Lindsley
2011188
2
Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors
Chemical Reviews ·Craig W. Lindsley, Kyle A. Emmitte, Corey R. Hopkins, Thomas M. Bridges, Karen J. Gregory, Colleen M. Niswender, P. Jeffrey Conn
2016138
3
In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1
Molecular Cancer Therapeutics ·Timothy J. Lansing, Randy T. McConnell, Derek R. Duckett, Glenn Spehar, Victoria B. Knick, Daniel F. Hassler, Nobuhiro Noro, Masaaki Furuta, Kyle A. Emmitte, Tona M. Gilmer, Robert A. Mook, Mui Cheung
2007121
4
Total Synthesis of (+)-Laurencin:  An Asymmetric Alkylation−Ring-Closing Metathesis Approach to Medium Ring Ethers
Organic Letters ·Michael T. Crimmins, Kyle A. Emmitte
199993
5
Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors
Nucleic Acids Research ·Fei Huang, Nadish Goyal, Katherine Sullivan, Kritika Hanamshet, Mikir Patel, Olga M. Mazina, Charles X. Wang, W. Frank An, James Spoonamore, Shailesh Metkar, Kyle A. Emmitte, Simon Cocklin, Tomasz Skórski, Alexander V. Mazin
201680
6
Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction
Proceedings of the National Academy of Sciences ·Adam G. Walker, Cody J. Wenthur, Zixiu Xiang, Jerri M. Rook, Kyle A. Emmitte, Colleen M. Niswender, Craig W. Lindsley, P. Jeffrey Conn
201578
7
Diastereoselective Alkylations of Oxazolidinone Glycolates:  A Useful Extension of the Evans Asymmetric Alkylation
Organic Letters ·Michael T. Crimmins, Kyle A. Emmitte, Jason D. Katz
200075
8
Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships
Molecular Pharmacology ·Karen J. Gregory, Meredith J. Noetzel, Jerri M. Rook, Paige N. Vinson, Shaun R. Stauffer, Alice L. Rodriguez, Kyle A. Emmitte, Ya Zhou, Aspen Chun, Andrew S. Felts, Brian A. Chauder, Craig W. Lindsley, Colleen M. Niswender, P. Jeffrey Conn
201271
9
Ring closing metathesis for the formation of medium ring ethers: the total synthesis of (−)-isolaurallene
Tetrahedron ·Michael T. Crimmins, Kyle A. Emmitte, Allison L. Choy
200265
10
Antitumor Activity of GSK1904529A, a Small-molecule Inhibitor of the Insulin-like Growth Factor-I Receptor Tyrosine Kinase
Clinical Cancer Research ·Peter Sabbatini, Jason L. Rowand, Arthur Groy, Susan Korenchuk, Qi Liu, Charity Atkins, Melissa Dumble, Jingsong Yang, Kelly K. Anderson, Brian J. Wilson, Kyle A. Emmitte, Sridhar K. Rabindran, Rakesh Kumar
200962
11
Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents
Journal of Medicinal Chemistry ·Julie L. Engers, Alice L. Rodriguez, Leah C. Konkol, Ryan D. Morrison, Analisa D. Thompson, Frank W. Byers, Anna L. Blobaum, Sichen Chang, Daryl F. Venable, Matthew T. Loch, Colleen M. Niswender, J. Scott Daniels, Carrie K. Jones, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte
201555
12
Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding
Bioorganic & Medicinal Chemistry Letters ·Kyle A. Emmitte, George M. Adjebang, C. Webb Andrews, Jennifer G. Badiang Alberti, Ramesh Bambal, Stanley D. Chamberlain, Ronda G. Davis‐Ward, Hamilton D. Dickson, Daniel F. Hassler, Keith R. Hornberger, Jeffrey R. Jackson, Kevin W. Kuntz, Timothy J. Lansing, Robert A. Mook, Kristen E. Nailor, Mark A. Pobanz, Stephon C. Smith, Chiu-Mei Sung, Mui Cheung
200953
13
Recent Advances in the Design and Development of Novel Negative Allosteric Modulators of mGlu5
ACS Chemical Neuroscience ·Kyle A. Emmitte
201151
14
mGlu5negative allosteric modulators: a patent review (2010 – 2012)
Expert Opinion on Therapeutic Patents ·Kyle A. Emmitte
201350
15
A Novel Class of Succinimide-Derived Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 1 Provides Insight into a Disconnect in Activity between the Rat and Human Receptors
ACS Chemical Neuroscience ·Hyekyung P. Cho, Darren W. Engers, Daryl F. Venable, Colleen M. Niswender, Craig W. Lindsley, P. Jeffrey Conn, Kyle A. Emmitte, Alice L. Rodriguez
201448
16
Discovery of (R)-(2-Fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-Hydroxypiperidin-1-yl)methanone (ML337), An mGlu3 Selective and CNS Penetrant Negative Allosteric Modulator (NAM)
Journal of Medicinal Chemistry ·Cody J. Wenthur, Ryan D. Morrison, Andrew S. Felts, Katrina A. Smith, Julie L. Engers, Frank W. Byers, J. Scott Daniels, Kyle A. Emmitte, P. Jeffrey Conn, Craig W. Lindsley
201347
17
Identification of Specific Ligand–Receptor Interactions That Govern Binding and Cooperativity of Diverse Modulators to a Common Metabotropic Glutamate Receptor 5 Allosteric Site
ACS Chemical Neuroscience ·Karen J. Gregory, Elizabeth D. Nguyen, Chrysa Malosh, Jeffrey Mendenhall, Jessica Z. Zic, Brittney S. Bates, Meredith J. Noetzel, Emma F. Squire, Eric M. Turner, Jerri M. Rook, Kyle A. Emmitte, Shaun R. Stauffer, Craig W. Lindsley, Jens Meiler, P. Jeffrey Conn
201443
18
Discovery of 2‐(2‐Benzoxazoyl amino)‐4‐Aryl‐5‐Cyanopyrimidine as Negative Allosteric Modulators (NAMs) of Metabotropic Glutamate Receptor 5 (mGlu5): From an Artificial Neural Network Virtual Screen to an In Vivo Tool Compound
ChemMedChem ·Ralf Mueller, Eric S. Dawson, Jens Meiler, Alice L. Rodriguez, Brian A. Chauder, Brittney S. Bates, Andrew S. Felts, Jeffrey P. Lamb, Usha N. Menon, Sataywan B. Jadhav, Alexander S. Kane, Carrie K. Jones, Karen J. Gregory, Colleen M. Niswender, P. Jeffrey Conn, Christopher M. Olsen, Danny G. Winder, Kyle A. Emmitte, Craig W. Lindsley
201240
19
Recent progress in the discovery and development of negative allosteric modulators of mGluR5.
PubMed ·Craig W. Lindsley, Kyle A. Emmitte
200939
20
mGlu5negative allosteric modulators: a patent review (2013 - 2016)
Expert Opinion on Therapeutic Patents ·Kyle A. Emmitte
201737

About Kyle A. Emmitte

Kyle A. Emmitte is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Organic Chemistry, Environmental Chemistry and Cell Biology, having authored 70 papers that have together received 2.2k indexed citations. Recurring topics across this work include Neuroscience and Neuropharmacology Research (41 papers), Receptor Mechanisms and Signaling (24 papers), Ion channel regulation and function (10 papers), Chemical Synthesis and Analysis (9 papers), Pharmacological Receptor Mechanisms and Effects (9 papers), Synthetic Organic Chemistry Methods (8 papers), Nicotinic Acetylcholine Receptors Study (5 papers) and Marine Toxins and Detection Methods (5 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (985 citations), Biological Psychiatry (58 citations), Molecular Biology (1.4k citations), Organic Chemistry (558 citations) and Toxicology (48 citations). Kyle A. Emmitte has collaborated with scholars based in United States, Australia and United Kingdom. Frequent co-authors include Craig W. Lindsley, Michael T. Crimmins, P. Jeffrey Conn, Colleen M. Niswender, Corey R. Hopkins, Alice L. Rodriguez, Andrew S. Felts, Karen J. Gregory, J. Scott Daniels and Carrie K. Jones. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, ACS Chemical Neuroscience, Expert Opinion on Therapeutic Patents and Organic Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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