Jonathan C. O’Connell

1.4k citations

19 papers · 660 · h-index 14

Impact in

Cellular and Molecular Neuroscience top 10%
- Neuropeptides and Animal Physiology
Molecular Biology
- Receptor Mechanisms and Signaling
- Phosphodiesterase function and regulation
- Pharmacological Receptor Mechanisms and Effects
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Chemical Synthesis and Analysis

Papers in

Molecular Biology 15
- Receptor Mechanisms and Signaling 7
- Phosphodiesterase function and regulation 3
- Chemical Synthesis and Analysis 3
- Pharmacological Receptor Mechanisms and Effects 3
Cellular and Molecular Neuroscience 7
- Neuropeptides and Animal Physiology 6
- Neuroscience and Neuropharmacology Research 2

Co-authors: Martyn Banks (11 shared papers)Neil T. Burford (6 shared papers)Andrew Alt (7 shared papers)Miles D. Houslay (3 shared papers)Graeme B. Bolger (2 shared papers)Tom S. Wehrman (3 shared papers)Samuel W. Gerritz (4 shared papers)John R. Traynor (2 shared papers)
Journals: SLAS DISCOVERY (7 papers)Journal of Medicinal Chemistry (2 papers)Assay and Drug Development Technologies (1 paper)Bioorganic & Medicinal Chemistry Letters (1 paper)Biochemical Society Transactions (1 paper)
Partner nations: United States Germany United Kingdom

In The Last Decade

Jonathan C. O’Connell

19 papers receiving 631 citations

Peers

Countries citing papers authored by Jonathan C. O’Connell

Since Specialization

Citations

This map shows the geographic impact of Jonathan C. O’Connell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan C. O’Connell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan C. O’Connell more than expected).

Fields of papers citing papers by Jonathan C. O’Connell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan C. O’Connell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan C. O’Connell. The network helps show where Jonathan C. O’Connell may publish in the future.

Co-authors

The 25 scholars most cited alongside Jonathan C. O’Connell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jonathan C. O’Connell Line = papers co-authored together Jonathan C. O’Connell links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor Proceedings of the National Academy of Sciences ·Neil T. Burford, Mary J. Clark, Tom S. Wehrman, Samuel W. Gerritz, Martyn Banks, Jonathan C. O’Connell, John R. Traynor, Andrew Alt	2013	135
2	The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5) Biochemical Journal ·Jonathan C. O’Connell, J. Fraser McCALLUM, Ian McPhee, Jill M. WAKEFIELD, Emma S. Houslay, William Wishart, Graeme B. Bolger, Margaret C. Frame, Miles D. Houslay	1996	93
3	Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1) Bioorganic & Medicinal Chemistry Letters ·Ashok V. Purandare, Zhong Chen, Tram Huynh, Suhong Pang, Jieping Geng, Wayne Vaccaro, Michael A. Poss, Jonathan C. O’Connell, Kimberly Nowak, Lata Jayaraman	2008	77
4	Discovery, Synthesis, and Molecular Pharmacology of Selective Positive Allosteric Modulators of the δ-Opioid Receptor Journal of Medicinal Chemistry ·Neil T. Burford, Kathryn E. Livingston, Meritxell Canals, Molly R. Ryan, Lauren Budenholzer, Ying Han, Yi Shang, John J. Herbst, Jonathan C. O’Connell, Martyn Banks, Litao Zhang, Marta Filizola, Daniel L. Bassoni, Tom S. Wehrman, Arthur Christopoulos, John R. Traynor, Samuel W. Gerritz, Andrew Alt	2015	63
5	The unique N‐terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains FEBS Letters ·Matthew Beard, Jonathan C. O’Connell, Graeme B. Bolger, Miles D. Houslay	1999	60
6	Evidence for Classical Cholinergic Toxicity Associated with Selective Activation of M1 Muscarinic Receptors Journal of Pharmacology and Experimental Therapeutics ·Andrew Alt, Annapurna Pendri, R.L. Bertekap, Guoping Li, Yulia Benitex, Michelle Nophsker, Kristin L. Rockwell, Neil T. Burford, Chi Shing Sum, (unknown), John J. Herbst, (unknown), Adam Hendricson, Mary Ellen Cvijic, Ryan S. Westphal, Jonathan C. O’Connell, Martyn Banks, L. Zhang, Robert G. Gentles, (unknown), (unknown), John E. Macor	2015	36
7	Synthesis of Multifunctional 2-Aminobenzimidazoles on DNA via Iodine-Promoted Cyclization Organic Letters ·Liqiang Su, Jing Feng, Ting Peng, Jinqiao Wan, Jing Fan, Jin Li, Jonathan C. O’Connell, David R. Lancia, G. Joseph Franklin, Guansai Liu	2020	36
8	Identification of Selective Agonists and Positive Allosteric Modulators for µ- and δ-Opioid Receptors from a Single High-Throughput Screen SLAS DISCOVERY ·Neil T. Burford, Tom S. Wehrman, Daniel L. Bassoni, Jonathan C. O’Connell, Martyn Banks, Litao Zhang, Andrew Alt	2014	28
9	Use of Cryopreserved Transiently Transfected Cells in High-Throughput Pregnane X Receptor Transactivation Assay SLAS DISCOVERY ·Zhengrong Zhu, Jaime Puglisi, David Connors, Jeremy Stewart, John J. Herbst, Anthony M. Marino, Michael Sinz, Jonathan C. O’Connell, Martyn Banks, Kenneth E.J. Dickinson, Angela Cacace	2007	20
10	Small Molecule Receptor Protein Tyrosine Phosphatase γ (RPTPγ) Ligands That Inhibit Phosphatase Activity via Perturbation of the Tryptophan–Proline–Aspartate (WPD) Loop Journal of Medicinal Chemistry ·S. Sheriff, Brett R. Beno, Weixu Zhai, Walter A. Kostich, Patricia A. McDonnell, Kevin Kish, Valentina Goldfarb, Mian Gao, Susan E. Kiefer, Joseph Yanchunas, Yanling Huang, Shuhao Shi, Shirong Zhu, Carolyn D. Dzierba, Joanne J. Bronson, John E. Macor, Kingsley K. Appiah, Ryan S. Westphal, Jonathan C. O’Connell, Samuel W. Gerritz	2011	18
11	Identification of Small Molecules That Selectively Inhibit Diacylglycerol Lipase–α Activity SLAS DISCOVERY ·Kingsley K. Appiah, Yuval Blat, Barbara Robertson, Bradley C. Pearce, Donna L. Pedicord, Robert G. Gentles, Xuan‐Chuan Yu, Faika Mseeh, Nghi Nguyen, Jonathan C. Swaffield, David Harden, Ryan S. Westphal, Martyn Banks, Jonathan C. O’Connell	2013	16
12	Development of Novel, 384-Well High-Throughput Assay Panels for Human Drug Transporters: Drug Interaction and Safety Assessment in Support of Discovery Research SLAS DISCOVERY ·Huaping Tang, Ding Ren Shen, Yong–Hae Han, Yan Kong, Praveen Balimane, Anthony M. Marino, Mian Gao, Sophie Wu, Dianlin Xie, Matthew G. Soars, Jonathan C. O’Connell, A. David Rodrigues, Litao Zhang, Mary Ellen Cvijic	2013	15
13	The Impact of Variable Selection Coverage on Detection of Ligands from a DNA-Encoded Library Screen SLAS DISCOVERY ·Kelly A. McCarthy, G. Joseph Franklin, David R. Lancia, Martin Olbrot, Eneida Pardo, Jonathan C. O’Connell, Christopher S. Kollmann	2020	14
14	Alternative splicing of the type-IVA cyclic AMP phosphodiesterase gene provides isoform variants with distinct N-terminal domains fused to a common, soluble catalytic unit: ‘designer’ changes in Vmax, stability and membrane association Biochemical Society Transactions ·Miles D. Houslay, Grant Scotland, L Pooley, Sandra Spence, Ian Wilkinson, Fraser McCallum, Pascale Julien, Graham Rena, Alison M. Michie, Suat Erdoğan, Li‐Fan Zeng, Jonathan C. O’Connell, Edward S. Tobias, Iain MacPhee	1995	13
15	Development of a High-Throughput Calcium Flux Assay for Identification of All Ligand Types Including Positive, Negative, and Silent Allosteric Modulators for G Protein-Coupled Receptors Assay and Drug Development Technologies ·Devin J. Noblin, Robert L. Bertekap, Neil T. Burford, Adam Hendricson, Litao Zhang, Ronald J. Knox, Martyn Banks, Jonathan C. O’Connell, Andrew Alt	2012	11
16	Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists SLAS DISCOVERY ·Ying‐Jie Zhu, John B. Watson, Mengjie Chen, Ding Ren Shen, Melissa Yarde, Michele Agler, Neil T. Burford, Andrew Alt, Sukhanya Jayachandra, Mary Ellen Cvijic, Litao Zhang, Alaric J. Dyckman, Jenny Xie, Jonathan C. O’Connell, Martyn Banks, Andrea D. Weston	2014	10
17	Challenges and Opportunities in Enabling High-Throughput, Miniaturized High Content Screening Methods in molecular biology ·Debra Nickischer, Lisa Elkin, Normand J. Cloutier, Jonathan C. O’Connell, Martyn Banks, Andrea D. Weston	2017	9
18	A High-Throughput Screen for Receptor Protein Tyrosine Phosphatase–γ Selective Inhibitors SLAS DISCOVERY ·Kingsley K. Appiah, Walter A. Kostich, Samuel W. Gerritz, Yanling Huang, Brian D. Hamman, Jason Allen, Wandong Zhang, Thomas H. Lanthorn, Charles F. Albright, Ryan S. Westphal, Martyn Banks, Jonathan C. O’Connell	2011	5
19	Studying GPCR trafficking using automated HCS tools Ying‐Jie Zhu, Michele Agler, Andrew Alt, Jonathan C. O’Connell, Martyn Banks, Jenny Xie	2010	1

About Jonathan C. O’Connell

Jonathan C. O’Connell is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Immunology, Organic Chemistry and Pharmacology, having authored 19 papers that have together received 660 indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (7 papers), Neuropeptides and Animal Physiology (6 papers), Phosphodiesterase function and regulation (3 papers), Chemical Synthesis and Analysis (3 papers), Pharmacological Receptor Mechanisms and Effects (3 papers), Galectins and Cancer Biology (2 papers), Neuroscience and Neuropharmacology Research (2 papers) and Pharmacogenetics and Drug Metabolism (2 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (210 citations), Molecular Biology (538 citations), Pharmacology (125 citations), Pharmacology (28 citations) and Organic Chemistry (69 citations). Jonathan C. O’Connell has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Martyn Banks, Neil T. Burford, Andrew Alt, Miles D. Houslay, Graeme B. Bolger, Tom S. Wehrman, Samuel W. Gerritz, John R. Traynor, Mary J. Clark and Matthew Beard. Their work appears in journals such as SLAS DISCOVERY, Journal of Medicinal Chemistry, Assay and Drug Development Technologies, Bioorganic & Medicinal Chemistry Letters and Biochemical Society Transactions.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Jonathan C. O’Connell

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