Jon H. Come

1.9k citations

19 papers · 1.4k · 1 hit paper · h-index 12

Impact in

Neurology top 1%
- Neurological diseases and metabolism
Nutrition and Dietetics top 2%
- Trace Elements in Health

Papers in

Molecular Biology 14
- Protein Kinase Regulation and GTPase Signaling 6
- Prion Diseases and Protein Misfolding 4
- Melanoma and MAPK Pathways 3
- Receptor Mechanisms and Signaling 2
- DNA and Nucleic Acid Chemistry 2
Organic Chemistry 11
- Carbohydrate Chemistry and Synthesis 3
- Catalytic C–H Functionalization Methods 2

Co-authors: Peter T. Lansbury (4 shared papers)P. E. Fraser (1 shared paper)Suzette A. Priola (2 shared papers)Gregory J. Raymond (2 shared papers)Byron Caughey (2 shared papers)Bruce Chesebro (2 shared papers)David A. Kocisko (2 shared papers)Upul K. Bandarage (8 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (5 papers)Tetrahedron Letters (2 papers)Journal of the American Chemical Society (2 papers)The Journal of Organic Chemistry (1 paper)Nature (1 paper)
Partner nations: United States Poland

In The Last Decade

Jon H. Come

17 papers receiving 1.4k citations

Jon H. Come's Hit Papers

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Cell-free formation of protease-resistant prion protein 1994 · 730 citations

Peers

Countries citing papers authored by Jon H. Come

Since Specialization

Citations

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Fields of papers citing papers by Jon H. Come

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jon H. Come. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jon H. Come. The network helps show where Jon H. Come may publish in the future.

Co-authors

The 25 scholars most cited alongside Jon H. Come, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jon H. Come Line = papers co-authored together Jon H. Come links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Cell-free formation of protease-resistant prion protein Nature ·David A. Kocisko, Jon H. Come, Suzette A. Priola, Bruce Chesebro, Gregory J. Raymond, Peter T. Lansbury, Byron Caughey Hit paper breakdown →	1994	730
2	A kinetic model for amyloid formation in the prion diseases: importance of seeding. Proceedings of the National Academy of Sciences ·Jon H. Come, P. E. Fraser, Peter T. Lansbury	1993	342
3	A Three-Hybrid Approach to Scanning the Proteome for Targets of Small Molecule Kinase Inhibitors Chemistry & Biology ·Frank Becker, Krishna K. Murthi, Chase C. Smith, Jon H. Come, Nuria Costa-Roldán, Christine Kaufmann, Urs Hanke, Carsten Degenhart, Sabine W. Baumann, Wolfgang Wallner, Andrea B. Huber, Séverine Dédier, Simone Dill, David Kinsman, Mark Hediger, Nicholas Bockovich, Sebastian Meier‐Ewert, Arthur F. Kluge, Nikolai Kley	2004	106
4	Small-Molecule Immunostimulants. Synthesis and Activity of 7,8-Disubstituted Guanosines and Structurally Related Compounds Journal of Medicinal Chemistry ·Allen B. Reitz, Michael Goodman, Barbara L. Pope, Dennis Argentieri, Stanley C. Bell, Levelle E. Burr, Erika Chourmouzis, Jon H. Come, J H Goodman	1994	49
5	Novel thiol-based TACE inhibitors. Part 2: Rational design, synthesis, and SAR of thiol-containing aryl sulfones Bioorganic & Medicinal Chemistry Letters ·Upul K. Bandarage, Tiansheng Wang, Jon H. Come, Emanuele Perola, Yunyi Wei, B. Govinda Rao	2007	31
6	Mechanistic and preparative studies of the intramolecular photocyclization of methylated 2-(4-pentenyl)tropones The Journal of Organic Chemistry ·Ken S. Feldman, Jon H. Come, Benedict J. Kosmider, Pamela M. Smith, David P. Rotella, Ming Jung Wu	1989	28
7	Novel thiol-based TACE inhibitors: Rational design, synthesis, and SAR of thiol-containing aryl sulfonamides Bioorganic & Medicinal Chemistry Letters ·B. Govinda Rao, Upul K. Bandarage, Tiansheng Wang, Jon H. Come, Emanuele Perola, Yunyi Wei, Shi‐Kai Tian, Jeffrey O. Saunders	2007	26
8	Predisposition of prion protein homozygotes to Creutzfeldt-Jakob disease can be explained by a nucleation-dependent polymerization mechanism Journal of the American Chemical Society ·Jon H. Come, Peter T. Lansbury	1994	26
9	ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors Bioorganic & Medicinal Chemistry Letters ·Upul K. Bandarage, Jingrong Cao, Jon H. Come, John J. Court, Huai Gao, Marc Jacobs, Craig Marhefka, Suganthi Nanthakumar, Jeremy Green	2018	25
10	4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: Potent and selective p70S6 kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Upul K. Bandarage, Brian Hare, Jonathan D. Parsons, Ly Pham, Craig Marhefka, Guy W. Bemis, Qing Tang, Cameron Stuver Moody, Steve Rodems, Sundeep Shah, Christopher Adams, Jose E. Guerrero Bravo, Emmanuelle Charonnet, Vladimir Savić, Jon H. Come, Jeremy Green	2009	22
11	Synthesis of eight-membered carbocycles via intramolecular [6.pi. + 2.pi.] photocycloaddition of alkenyl tropones Journal of the American Chemical Society ·Ken S. Feldman, Jon H. Come, Alan J. Freyer, Ben J. Kosmider, Cynthia M. Smith	1986	20
12	Discovery of a Novel Series of Potent and Selective Alkynylthiazole-Derived PI3Kγ Inhibitors ACS Medicinal Chemistry Letters ·Upul K. Bandarage, Alex M. Aronov, Jingrong Cao, Jon H. Come, Kevin M. Cottrell, Robert J.O. Davies, Simon Giroux, Marc Jacobs, Sudipta Mahajan, David Messersmith, Cameron Stuver Moody, Rebecca Swett, Jinwang Xu	2020	12
13	ROCK inhibitors 4: Structure-activity relationship studies of 7-azaindole-based rho kinase (ROCK) inhibitors Bioorganic & Medicinal Chemistry Letters ·Upul K. Bandarage, John J. Court, Huai Gao, Suganthini Nanthakumar, Jon H. Come, Simon Giroux, Jeremy Green	2020	10
14	Convenient synthesis of N-(4-(2-aminopyridin-4-yl)thiazol-2-yl)-2-phenylacetamides Tetrahedron Letters ·Upul K. Bandarage, Jon H. Come, Jeremy Green	2006	7
15	A convenient synthesis of 7-allyl-8-substituted guanosines Tetrahedron Letters ·Jon H. Come, Levelle E. Burr, R. Chen	1991	6
16	Guanosine Derivatives as Immunostimulants. Discovery of Loxoribine Nucleosides and Nucleotides ·Robert Chen, Michael Goodman, Dennis Argentieri, Stanley C. Bell, Levelle E. Burr, Jon H. Come, J H Goodman, Dieter H. Klaubert, Bruce E. Maryanoff, Barbara L. Pope, M. S. RAMPULLA, Mary R. Schott, Allen B. Reitz	1994	3
17	Synthesis of Novel 7‐Allyl‐8‐Substituted Guanosines Journal of the Chinese Chemical Society ·Jon H. Come, Dieter H. Klaubert, R. Chen	1991	1
18	Novel Thiol‐Based TACE Inhibitors: Rational Design, Synthesis, and SAR of Thiol‐Containing Aryl Sulfonamides. ChemInform ·B. Govinda Rao, Upul K. Bandarage, Tiansheng Wang, Jon H. Come, Emanuele Perola, Yunyi Wei, Shi‐Kai Tian, Jeffrey O. Saunders	2007	1
19	The Formation of Scrapie-Associated Prion Protein In Vitro Byron Caughey, Suzette A. Priola, David A. Kocisko, Gregory J. Raymond, Jon H. Come, Santosh Nandan, Bruce Chesebro, Peter T. Lansbury	1996	0

About Jon H. Come

Jon H. Come is a scholar working on Molecular Biology, Organic Chemistry, Oncology, Spectroscopy and Immunology, having authored 19 papers that have together received 1.4k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (6 papers), Prion Diseases and Protein Misfolding (4 papers), Carbohydrate Chemistry and Synthesis (3 papers), Melanoma and MAPK Pathways (3 papers), Catalytic C–H Functionalization Methods (2 papers), Receptor Mechanisms and Signaling (2 papers), Mass Spectrometry Techniques and Applications (2 papers) and DNA and Nucleic Acid Chemistry (2 papers). The work is most often cited by research in Neurology (550 citations), Nutrition and Dietetics (407 citations), Molecular Biology (1.2k citations), Physiology (188 citations) and Organic Chemistry (154 citations). Jon H. Come has collaborated with scholars based in United States and Poland. Frequent co-authors include Peter T. Lansbury, P. E. Fraser, Suzette A. Priola, Gregory J. Raymond, Byron Caughey, Bruce Chesebro, David A. Kocisko, Upul K. Bandarage, B. Govinda Rao and Ken S. Feldman. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Tetrahedron Letters, Journal of the American Chemical Society, The Journal of Organic Chemistry and Nature.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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