John Throup

2.9k citations

32 papers · 2.2k · 2 hit papers · h-index 13

Impact in

Endocrinology top 2%
- Vibrio bacteria research studies
Molecular Medicine top 5%
- Antibiotic Resistance in Bacteria

Papers in

Molecular Biology 15
- Bacterial biofilms and quorum sensing 5
- RNA and protein synthesis mechanisms 3
- Sphingolipid Metabolism and Signaling 3
Immunology 13
- Psoriasis: Treatment and Pathogenesis 11

Co-authors: Paul Williams (6 shared papers)Gordon S.A.B. Stewart (6 shared papers)Simon Swift (3 shared papers)Barrie W. Bycroft (3 shared papers)Michael K. Winson (3 shared papers)Siri Ram Chhabra (3 shared papers)George P. C. Salmond (2 shared papers)Steve Atkinson (1 shared paper)
Journals: Molecular Microbiology (4 papers)Annals of the Rheumatic Diseases (3 papers)Journal of the American Academy of Dermatology (3 papers)Journal of Crohn s and Colitis (2 papers)Molecular Genetics and Metabolism (2 papers)
Partner nations: United States United Kingdom Germany

In The Last Decade

John Throup

32 papers receiving 2.2k citations

John Throup's Hit Papers

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Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: Efficacy and safety results from the 52-week, randomized, double-blinded, placebo-controlled phase 3 POETYK PSO-1 trial 2022 · 237 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2022 Journal of the American Academy of Dermatology
2022 Journal of the American Academy of Dermatology

Peers

Countries citing papers authored by John Throup

Since Specialization

Citations

This map shows the geographic impact of John Throup's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Throup with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Throup more than expected).

Fields of papers citing papers by John Throup

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Throup. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Throup. The network helps show where John Throup may publish in the future.

Co-authors

The 25 scholars most cited alongside John Throup, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John Throup Line = papers co-authored together John Throup links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 32 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Construction and analysis ofluxCDABE-based plasmid sensors for investigatingN-acyl homoserine lactone-mediated quorum sensing FEMS Microbiology Letters ·Michael K. Winson, Simon Swift, Leigh Fish, John Throup, Frieda JÃ ̧rgensen, Siri Ram Chhabra, Barrie W. Bycroft, Paul Williams, Gordon S.A.B. Stewart	1998	492
2	A genomic analysis of two‐component signal transduction in Streptococcus pneumoniae Molecular Microbiology ·John Throup, Kristin K. Koretke, Alexander P. Bryant, Karen Ingraham, Alison F. Chalker, Yigong Ge, Andrea Marra, Nicola G. Wallis, James R. Brown, David Holmes, Martin Rosenberg, Martin Burnham	2000	261
3	Quorum sensing: a population-density component in the determination of bacterial phenotype Trends in Biochemical Sciences ·Simon Swift, John Throup, Paul Williams, George P. C. Salmond, Gordon S.A.B. Stewart	1996	240
4	Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: Efficacy and safety results from the 52-week, randomized, double-blinded, placebo-controlled phase 3 POETYK PSO-1 trial Journal of the American Academy of Dermatology ·April W. Armstrong, Melinda Gooderham, Richard B. Warren, Kim Papp, Bruce Strober, Diamant Thaçi, Akimichi Morita, Jacek C. Szepietowski, Shinichi Imafuku, Elizabeth Colston, John Throup, Sudeep Kundu, Steve Schoenfeld, Misti Linaberry, Subhashis Banerjee, Andrew Blauvelt Hit paper breakdown →	2022	237
5	Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: Efficacy and safety results from the 52-week, randomized, double-blinded, phase 3 Program fOr Evaluation of TYK2 inhibitor psoriasis second trial Journal of the American Academy of Dermatology ·Bruce Strober, Diamant Thaçi, Howard Sofen, Leon Kircik, Kenneth B. Gordon, Peter Foley, Phoebe Rich, C. Paul, Jerry Bagel, Elizabeth Colston, John Throup, Sudeep Kundu, Chitra Sekaran, Misti Linaberry, Subhashis Banerjee, Kim Papp Hit paper breakdown →	2022	190
6	A novel strategy for the isolation of luxl homologues: evidence for the widespread distribution of a LuxR:Luxl superfamily in enteric bacteria Molecular Microbiology ·Simon Swift, Michael K. Winson, Pan F. Chan, Nigel J. Bainton, M. Birdsall, Philip J. Reeves, Catherine Rees, Siri Ram Chhabra, Philip J. Hill, John Throup, Barrie W. Bycroft, George P. C. Salmond, Paul Williams, Gordon S.A.B. Stewart	1993	169
7	A hierarchical quorum‐sensing system in Yersinia pseudotuberculosis is involved in the regulation of motility and clumping Molecular Microbiology ·Steve Atkinson, John Throup, Gordon S.A.B. Stewart, Paul Williams	1999	143
8	Characterisation of the yenI/yenR locus from Yersinia enterocolitica mediating the synthesis of two N‐acylhomoserine lactone signal molecules Molecular Microbiology ·John Throup, Miguel Cámara, Geoffrey S. Briggs, Michael K. Winson, Siri Ram Chhabra, Barrie W. Bycroft, Paul Williams, Gordon S.A.B. Stewart	1995	125
9	Plants genetically modified to produce N-acylhomoserine lactones communicate with bacteria Nature Biotechnology ·Rupert G. Fray, John Throup, Mavis Daykin, Andrew D. Wallace, Paul Williams, Gordon S.A.B. Stewart, Donald Grierson	1999	96
10	Selectivity Profile of the Tyrosine Kinase 2 Inhibitor Deucravacitinib Compared with Janus Kinase 1/2/3 Inhibitors Dermatology and Therapy ·Anjaneya Chimalakonda, James R. Burke, Lihong Cheng, Ian M. Catlett, Michael Tagen, Qihong Zhao, Aditya Patel, Jun Shen, Ihab Girgis, Subhashis Banerjee, John Throup	2021	90
11	The srhSR Gene Pair from Staphylococcus aureus: Genomic and Proteomic Approaches to the Identification and Characterization of Gene Function Biochemistry ·John Throup, Francesca Zappacosta, R. Dwayne Lunsford, Roland S. Annan, Steven A. Carr, John T. Lonsdale, Alexander P. Bryant, Damien McDevitt, Martin Rosenberg, Martin Burnham	2001	87
12	Biochemical Characterization of the First Essential Two-Component Signal Transduction System from <i>Staphylococcus aureus</i> and <i>Streptococcus pneumoniae</i> Microbial Physiology ·Valerie A. Clausen, Weonhye Bae, John Throup, Martin Burnham, Martin Rosenberg, Nicola G. Wallis	2003	30
13	POS1042 EFFICACY AND SAFETY OF DEUCRAVACITINIB, AN ORAL, SELECTIVE TYROSINE KINASE 2 (TYK2) INHIBITOR, COMPARED WITH PLACEBO AND APREMILAST IN MODERATE TO SEVERE PLAQUE PSORIASIS: RESULTS FROM THE PHASE 3 POETYK PSO-1 STUDY Annals of the Rheumatic Diseases ·April W. Armstrong, Melinda Gooderham, Richard B. Warren, Kim Papp, Bruce Strober, Diamant Thaçi, Elizabeth Colston, John Throup, S. Kundu, Subhashis Banerjee, Andrew Blauvelt	2021	21
14	Lack of Electrocardiographic Effects of Deucravacitinib in Healthy Subjects Clinical Pharmacology in Drug Development ·Anjaneya Chimalakonda, Shalabh Singhal, Raymond B. Darbenzio, Randy Dockens, David Marchisin, Subhashis Banerjee, Ihab Girgis, John Throup, Bing He, Urvi Aras, Bindu Murthy	2022	11
15	Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma Frontiers in Pharmacology ·Alison Portnoy, Sanjay Kumar, David J. Behm, Kelly M. Mahar, Robert Noble, John Throup, Steven F. Russ	2013	10
16	Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 (TYK2) Inhibitor, Compared With Placebo and Apremilast in Moderate to Severe Psoriasis: Integrated Laboratory Parameter Results From the Phase 3 POETYK PSO-1 and POETYK PSO-2 Trials SKIN The Journal of Cutaneous Medicine ·Diamant Thaçi, Kenneth B. Gordon, Melinda Gooderham, Bruce Strober, Neil J. Korman, Subhashis Banerjee, Subhashis Banerjee, Elizabeth Colston, Jonghyeon Kim, John Throup, Akimichi Morita	2021	4
17	Selective Inhibition of Tyrosine Kinase 2 With Deucravacitinib (BMS-986165) Compared With Janus Kinase 1−3 Inhibitors SKIN The Journal of Cutaneous Medicine ·Anjaneya Chimalakonda, James R. Burke, Lihong Cheng, Ian M. Catlett, Aditya Patel, Jun Shen, Ihab Girgis, Subhashis Banerjee, John Throup	2020	4
18	A SMALL MOLECULE SLC6A19 INHIBITOR INCREASES URINARY PHENYLALANINE EXCRETION AND REDUCES ITS PATHOGENIC PLASMA ACCUMULATION IN A PHENYLKETONURIA MOUSE MODEL Molecular Genetics and Metabolism ·Heike J. Wobst, Ryan Hollibaugh, Giovanni Muncipinto, Christopher T Burkhart, Daniel van Kalken, Andreu Viader, Heather Blanchette, Dean G. Brown, Nick Pullen, John Throup, Joel C. Barrish	2023	4
19	P638 BMS-986165, an oral selective tyrosine kinase 2 (TYK2) inhibitor, does not affect the pharmacokinetics of methotrexate in healthy subjects Journal of Crohn s and Colitis ·Anjaneya Chimalakonda, J Jones, Randy Dockens, John Throup, Subhashis Banerjee, Ihab Girgis	2019	3
20	Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 (TYK2) Inhibitor, in Moderate to Severe Plaque Psoriasis: 52-Week Efficacy Results From the Phase 3 POETYK PSO-1 and PSO-2 Trials SKIN The Journal of Cutaneous Medicine ·Richard B. Warren, April W. Armstrong, Melinda Gooderham, Bruce Strober, Diamant Thaçi, Shinichi Imafuku, Howard Sofen, Lynda Spelman, Neil J. Korman, Min Zheng, Elizabeth Colston, John Throup, Sundeep Kundu, Renata M. Kisa, Subhashis Banerjee, Andrew Blauvelt	2022	3

About John Throup

John Throup is a scholar working on Molecular Biology, Immunology, Oncology, Genetics and Radiology, Nuclear Medicine and Imaging, having authored 32 papers that have together received 2.2k indexed citations. Recurring topics across this work include Psoriasis: Treatment and Pathogenesis (11 papers), Cytokine Signaling Pathways and Interactions (7 papers), Bacterial biofilms and quorum sensing (5 papers), Bacterial Genetics and Biotechnology (5 papers), Monoclonal and Polyclonal Antibodies Research (4 papers), HER2/EGFR in Cancer Research (3 papers), RNA and protein synthesis mechanisms (3 papers) and Sphingolipid Metabolism and Signaling (3 papers). The work is most often cited by research in Endocrinology (244 citations), Molecular Medicine (149 citations), Microbiology (146 citations), Immunology (439 citations) and Genetics (566 citations). John Throup has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Paul Williams, Gordon S.A.B. Stewart, Simon Swift, Barrie W. Bycroft, Michael K. Winson, Siri Ram Chhabra, George P. C. Salmond, Steve Atkinson, Subhashis Banerjee and Martin Burnham. Their work appears in journals such as Molecular Microbiology, Annals of the Rheumatic Diseases, Journal of the American Academy of Dermatology, Journal of Crohn s and Colitis and Molecular Genetics and Metabolism.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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John Throup

John Throup's Hit Papers

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About John Throup

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