James T. MacGregor

11.6k citations

169 papers · 8.9k · 2 hit papers · h-index 47

Impact in

Cancer Research top 0.1%
- Carcinogens and Genotoxicity Assessment
Chemical Health and Safety top 0.2%

Papers in

Cancer Research 89
- Carcinogens and Genotoxicity Assessment 89
Molecular Biology 64
- DNA Repair Mechanisms 25
- Molecular Biology Techniques and Applications 9

Co-authors: Carol M. Wehr (17 shared papers)John A. Heddle (5 shared papers)Richard B. Everson (3 shared papers)Makoto Hayashi (15 shared papers)Marilyn J. Aardema (4 shared papers)Mark Hite (2 shared papers)Robert A. Hiatt (2 shared papers)Michael F. Salamone (2 shared papers)
Journals: Environmental and Molecular Mutagenesis (31 papers)Mutation Research/Genetic Toxicology and Environmental Mutagenesis (12 papers)Toxicological Sciences (12 papers)Mutagenesis (8 papers)Toxicology and Applied Pharmacology (6 papers)
Partner nations: United States United Kingdom Japan

In The Last Decade

James T. MacGregor

168 papers receiving 8.2k citations

James T. MacGregor's Hit Papers

align trajectories log scale

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage 1997 · 1.1k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1997 Proceedings of the National Academy of Sciences
1983 Mutation Research/Reviews in Genetic Toxicology

Peers

Countries citing papers authored by James T. MacGregor

Since Specialization

Citations

This map shows the geographic impact of James T. MacGregor's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James T. MacGregor with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James T. MacGregor more than expected).

Fields of papers citing papers by James T. MacGregor

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James T. MacGregor. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James T. MacGregor. The network helps show where James T. MacGregor may publish in the future.

Co-authors

The 25 scholars most cited alongside James T. MacGregor, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James T. MacGregor Line = papers co-authored together James T. MacGregor links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

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#	Work
1	Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage Proceedings of the National Academy of Sciences ·Benjamin C. Blount, M. M. Mack, Carol M. Wehr, James T. MacGregor, Robert A. Hiatt, Gene Wang, Sunitha N. Wickramasinghe, Richard B. Everson, Bruce N. Ames Hit paper breakdown →	1997	1146
2	The induction of micronuclei as a measure of genotoxicity Mutation Research/Reviews in Genetic Toxicology ·John A. Heddle, Mark Hite, Barbara Kirkhart, Kathleen H. Mavournin, James T. MacGregor, Gordon W. Newell, Michael F. Salamone Hit paper breakdown →	1983	639
3	Micronuclei as an index of cytogenetic damage: Past, present, and future Environmental and Molecular Mutagenesis ·John A. Heddle, M Cimino, Makoto Hayashi, F. Romagna, Michael D. Shelby, James D. Tucker, Ph. Vanparys, James T. MacGregor	1991	446
4	Guidelines for the conduct of micronucleus assays in mammalian bone marrow erythrocytes Mutation Research/Genetic Toxicology ·James T. MacGregor, John A. Heddle, Mark Hite, Barry H. Margolin, Clacs Ramel, Michael F. Salamone, Raymond R. Tice, D. Wild	1987	326
5	In vivo rodent erythrocyte micronucleus assay Mutation Research/Environmental Mutagenesis and Related Subjects ·Makoto Hayashi, Raymond R. Tice, James T. MacGregor, Diana Anderson, David H. Blakey, Micheline Kirsh-Volders, Frederick B. Oleson, Francesca Pacchierotti, F. Romagna, Hiroyasu Shimada, Sizuyo Sutou, Bernard Vannier	1994	278
6	Toxicology and genetic toxicology in the new era of “toxicogenomics”: impact of “-omics” technologies Mutation research. Fundamental and molecular mechanisms of mutagenesis ·Marilyn J. Aardema, James T. MacGregor	2002	268
7	Mutagenicity of plant flavonoids: Structural requirements for mutagenic activity in Salmonella typhimurium Mutation Research/Environmental Mutagenesis and Related Subjects ·James T. MacGregor, Leonard Jurd	1978	252
8	Trivalent Chromium: Assessing the Genotoxic Risk of an Essential Trace Element and Widely Used Human and Animal Nutritional Supplement Critical Reviews in Toxicology ·David A. Eastmond, James T. MacGregor, R.S. Slesinski	2008	235
9	Clastogen‐induced micronuclei in peripheral blood erythrocytes: The basis of an improved micronucleus test Environmental Mutagenesis ·James T. MacGregor, Carol M. Wehr, Daniel H. Gould	1980	197
10	In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring Environmental and Molecular Mutagenesis ·Makoto Hayashi, James T. MacGregor, D. Gatehouse, I.‐D. Adler, David H. Blakey, Stephen D. Dertinger, G. Krishna, Takeshi Morita, Antonella Russo, Shizuyo Sutou	2000	183
11	The in vivo erythrocyte micronucleus test: Measurement at steady state increases assay efficiency and permits integration with toxicity studies Fundamental and Applied Toxicology ·James T. MacGregor	1990	123
12	Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity Toxicologic Pathology ·Kendall B. Wallace, Elizabeth A. Hausner, Eugene H. Herman, Gordon D. Holt, James T. MacGregor, Alan Metz, Elizabeth Murphy, Ira Rosenblum, Frank D. Sistare, Malcolm J. York	2004	117
13	Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment Environmental and Molecular Mutagenesis ·George E. Johnson, Lya G. Soeteman‐Hernández, B. Bhaskar Gollapudi, Owen Bodger, Kerry L. Dearfield, Robert H. Heflich, J. Gregory Hixon, David P. Lovell, James T. MacGregor, Lynn H. Pottenger, Chad M. Thompson, L. Abraham, V. Thybaud, Jennifer Y. Tanir, Errol Zeiger, Jan van Benthem, Paul A. White	2014	115
14	Quantitative approaches for assessing dose–response relationships in genetic toxicology studies Environmental and Molecular Mutagenesis ·B. Bhaskar Gollapudi, George E. Johnson, Lya G. Soeteman‐Hernández, Lynn H. Pottenger, Kerry L. Dearfield, A. M. Jeffrey, Eric Julien, J.H. Kim, David P. Lovell, James T. MacGregor, Martha M. Moore, Jan van Benthem, Paul A. White, Errol Zeiger, V. Thybaud	2012	115
15	The persistence of micronuclei in peripheral blood erythrocytes: detection of chronic chromosome breakage in mice Mutation Research Letters ·Robert Schlegel, James T. MacGregor	1982	109
16	IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk Mutation Research/Genetic Toxicology and Environmental Mutagenesis ·James T. MacGregor, Roland Frötschl, Paul A. White, Kenny S. Crump, David A. Eastmond, Shoji Fukushima, Melanie Guérard, Makoto Hayashi, Lya G. Soeteman‐Hernández, George E. Johnson, Toshio Kasamatsu, Dan D. Levy, Takeshi Morita, Lutz Müller, Rita Schoeny, Maik J. Schuler, Véronique Thybaud	2014	103
17	IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs) Mutation Research/Genetic Toxicology and Environmental Mutagenesis ·James T. MacGregor, Roland Frötschl, Paul A. White, Kenny S. Crump, David A. Eastmond, Shoji Fukushima, Melanie Guérard, Makoto Hayashi, Lya G. Soeteman‐Hernández, Toshio Kasamatsu, Dan D. Levy, Takeshi Morita, Lutz Müller, Rita Schoeny, Maik J. Schuler, Véronique Thybaud, George E. Johnson	2014	102
18	Association of Marginal Folate Depletion With Increased Human Chromosomal Damage In Vivo: Demonstration by Analysis of Micronucleated Erythrocytes JNCI Journal of the National Cancer Institute ·Richard B. Everson, Carol M. Wehr, G.L. Erexson, James T. MacGregor	1988	100
19	Induction of hepatic mutations in lacI transgenic mice Mutagenesis ·Jon C. Mirsalis, Gabrielle S. Le Provost, Crystal D. Matthews, Richard T. Hamner, Janice E. Schindler, Kathleen O’Loughlin, James T. MacGregor, Jay M. Short	1993	97
20	Genetic effects of the flavonols quercetin, kaempferol, and galangin on Chinese hamster ovary cells in vitro Mutation Research/Environmental Mutagenesis and Related Subjects ·J.H. Carver, A.V. Carrano, James T. MacGregor	1983	94

About James T. MacGregor

James T. MacGregor is a scholar working on Cancer Research, Molecular Biology, Health, Toxicology and Mutagenesis, Plant Science and Food Science, having authored 169 papers that have together received 8.9k indexed citations. Recurring topics across this work include Carcinogens and Genotoxicity Assessment (89 papers), Effects and risks of endocrine disrupting chemicals (35 papers), DNA Repair Mechanisms (25 papers), Genetically Modified Organisms Research (18 papers), Molecular Biology Techniques and Applications (9 papers), Acute Lymphoblastic Leukemia research (7 papers), Radiation Effects and Dosimetry (7 papers) and Pesticide Exposure and Toxicity (6 papers). The work is most often cited by research in Cancer Research (3.8k citations), Chemical Health and Safety (130 citations), Health, Toxicology and Mutagenesis (2.2k citations), Rheumatology (1.0k citations) and Small Animals (363 citations). James T. MacGregor has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include Carol M. Wehr, John A. Heddle, Richard B. Everson, Makoto Hayashi, Marilyn J. Aardema, Mark Hite, Robert A. Hiatt, Michael F. Salamone, Leonard Jurd and Benjamin C. Blount. Their work appears in journals such as Environmental and Molecular Mutagenesis, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Toxicological Sciences, Mutagenesis and Toxicology and Applied Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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James T. MacGregor

James T. MacGregor's Hit Papers

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About James T. MacGregor

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