David A. Sinclair

85.5k citations
448 papers · 69.5k · 38 hit papers · h-index 104

Impact in

Papers in

David A. Sinclair

436 papers receiving 67.5k citations

David A. Sinclair's Hit Papers

Human trials exploring anti-aging medicines 2024 · 158 citations
1580+4+8Years since publication250500750

Peers

David A. Sinclair
Comparison fields: 5 of 222
  • Geriatrics and Gerontology 23.8k
  • Aging 9.2k
  • Physiology 5.0k
  • Physiology 19.0k
  • Biological Psychiatry 1.2k
Replace Claudio Franceschi with:
Claudio Franceschi Italy
Carlos López-Otı́n Spain
Judith Campisi United States
David Chaim Rubinsztein United Kingdom
Masayuki Yamamoto Japan
Daniel J. Klionsky United States
Robert A. Weinberg United States
Douglas R. Green United States
Markku Laakso Finland
Marı́a A. Blasco Spain
David A. Sinclair relative to Claudio Franceschi Italy Claudio Franceschi's profile →
Citations per field
00.5×2×4×6×7.9×
Claudio Franceschi · 1×
Citations per year

Countries citing papers authored by David A. Sinclair

Since Specialization
Citations

This map shows the geographic impact of David A. Sinclair's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David A. Sinclair with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David A. Sinclair more than expected).

Fields of papers citing papers by David A. Sinclair

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David A. Sinclair. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David A. Sinclair. The network helps show where David A. Sinclair may publish in the future.

Co-authors

The 25 scholars most cited alongside David A. Sinclair, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David A. Sinclair Line = papers co-authored together David A. Sinclair links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 448 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Resveratrol improves health and survival of mice on a high-calorie diet
Hit paper breakdown →
20063741
2
Guidelines for the use and interpretation of assays for monitoring autophagy
Hit paper breakdown →
20123543
3
Therapeutic potential of resveratrol: the in vivo evidence
Hit paper breakdown →
20063427
4
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
Hit paper breakdown →
20033256
5
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
Hit paper breakdown →
20042854
6
Mammalian Sirtuins: Biological Insights and Disease Relevance
Hit paper breakdown →
20101796
7
Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase
Hit paper breakdown →
20041701
8
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
Hit paper breakdown →
20041604
9
Sirtuins in mammals: insights into their biological function
Hit paper breakdown →
20071494
10
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Hit paper breakdown →
20071494
11
SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
Hit paper breakdown →
20121400
12
Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
Hit paper breakdown →
20131238
13
Extrachromosomal rDNA Circles— A Cause of Aging in Yeast
Hit paper breakdown →
19971222
14
The Intersection Between Aging and Cardiovascular Disease
Hit paper breakdown →
20121208
15
Metformin improves healthspan and lifespan in mice
Hit paper breakdown →
20131185
16
Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span
Hit paper breakdown →
20081022
17
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
Hit paper breakdown →
2007940
18
Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1
Hit paper breakdown →
2002857
19
Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival
Hit paper breakdown →
2007832
20
The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice
Hit paper breakdown →
2014779

About David A. Sinclair

David A. Sinclair is a scholar working on Geriatrics and Gerontology, Aging, Physiology, Molecular Biology and Physiology, having authored 448 papers that have together received 69.5k indexed citations. Recurring topics across this work include Sirtuins and Resveratrol in Medicine (122 papers), Genetics, Aging, and Longevity in Model Organisms (70 papers), Adipose Tissue and Metabolism (61 papers), Autophagy in Disease and Therapy (38 papers), Mitochondrial Function and Pathology (28 papers), Calcium signaling and nucleotide metabolism (21 papers), DNA Repair Mechanisms (20 papers) and Biochemical effects in animals (17 papers). The work is most often cited by research in Geriatrics and Gerontology (23.8k citations), Aging (9.2k citations), Physiology (5.0k citations), Physiology (19.0k citations) and Biological Psychiatry (1.2k citations). David A. Sinclair has collaborated with scholars based in United States, United Kingdom and Australia. Frequent co-authors include Joseph A. Baur, Leonard Guarente, Haim Yosef Cohen, Shaday Michán, Marcia C. Haigis, Kevin J. Bitterman, Konrad T. Howitz, Jason G. Wood, Brian J. North and Siva Lavu. Their work appears in journals such as Cochrane Database of Systematic Reviews, Cell Metabolism, Cell, Aging and Aging Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact