Clive McCarthy

1.1k citations

31 papers · 902 · h-index 19

Impact in

Physiology top 5%
- Alzheimer's disease research and treatments
- Adenosine and Purinergic Signaling
Organic Chemistry top 5%
- Synthesis and biological activity
- Radical Photochemical Reactions

Papers in

Organic Chemistry 11
- Synthesis and biological activity 5
Physiology 9
- Nitric Oxide and Endothelin Effects 5
- Alzheimer's disease research and treatments 2
- Adenosine and Purinergic Signaling 2

Co-authors: Keith A. Jones (4 shared papers)John R. Fozard (2 shared papers)John M. D. Storey (2 shared papers)Martin Gosling (4 shared papers)Henry L. Danahay (3 shared papers)Andrew J. Clark (1 shared paper)Pascal Furet (3 shared papers)Peter Drueckes (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (12 papers)Journal of Medicinal Chemistry (5 papers)Journal of Cystic Fibrosis (2 papers)Tetrahedron Letters (2 papers)European Journal of Medicinal Chemistry (2 papers)
Partner nations: Switzerland United Kingdom United States

In The Last Decade

Clive McCarthy

31 papers receiving 821 citations

Peers

Countries citing papers authored by Clive McCarthy

Since Specialization

Citations

This map shows the geographic impact of Clive McCarthy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Clive McCarthy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Clive McCarthy more than expected).

Fields of papers citing papers by Clive McCarthy

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Clive McCarthy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Clive McCarthy. The network helps show where Clive McCarthy may publish in the future.

Co-authors

The 25 scholars most cited alongside Clive McCarthy, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Clive McCarthy Line = papers co-authored together Clive McCarthy links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 31 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients Cancer Research ·Ralph Tiedt, Elisa Degenkolbe, Pascal Furet, B.A. Appleton, Sabrina Wagner, Joseph G. Schoepfer, David A. Ruddy, John E. Monahan	2011	113
2	Potent small molecule inhibitors of spleen tyrosine kinase (Syk) Bioorganic & Medicinal Chemistry Letters ·Justine Y. Q. Lai, Paul J. Cox, Rajesh Patel, Shazia Sadiq, David Aldous, Sukanthini Thurairatnam, Keith J. Smith, Savita Jagpal	2003	74
3	TMEM16A Potentiation: A Novel Therapeutic Approach for the Treatment of Cystic Fibrosis American Journal of Respiratory and Critical Care Medicine ·Henry L. Danahay, Sarah J Lilley, Holly Charlton, Juan R. Sabater, Brian M. Button, Clive McCarthy, Stephen P. Collingwood, Martin Gosling +1 other	2020	72
4	Chiral induction in aryl radical cyclisations Tetrahedron Letters ·Keith A. Jones, Clive McCarthy	1989	58
5	Macrocyclic BACE-1 inhibitors acutely reduce Aβ in brain after po application Bioorganic & Medicinal Chemistry Letters ·Andreas M. Lerchner, Rainer Machauer, Claudia Betschart, Siem J. Veenstra, Heinrich Rueeger, Clive McCarthy, Marina Tintelnot‐Blomley, Anne-Lise Jaton	2009	47
6	Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway Bioorganic & Medicinal Chemistry Letters ·Mohammed Shahid Akhlaq, Graham C. Bloomfield, Emma L. Budd, Brian J. Cox, Bernard M. Cuenoud, Peter M. Finan, Peter Gedeck, Julia Hatto	2012	46
7	Mapping the kinase domain of janus kinase 3 Bioorganic & Medicinal Chemistry Letters ·David Aldous, Shelley Amendola, Paul Bamborough, Colin P. Bright, Sarah Crowe, Paul R. Eastwood, Garry Fenton, Martyn L. Foster	2003	40
8	Aryl radical cyclisations: Quinoline, isoquinolone, and 1-benzazepin-2-onerings via 6- and 7-exo cyclisations Tetrahedron Letters ·Andrew J. Clark, Keith A. Jones, Clive McCarthy, John M. D. Storey	1991	38
9	Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Heinrich Rueeger, Jean‐Michel Rondeau, Clive McCarthy, Henrik Möbitz, Marina Tintelnot‐Blomley, Ulf Neumann, Sandrine Desrayaud	2011	38
10	Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors Bioorganic & Medicinal Chemistry Letters ·Carole Pissot‐Soldermann, Marc Gerspacher, Pascal Furet, Christoph Gaul, Philipp Holzer, Clive McCarthy, Thomas Radimerski, Catherine H. Régnier	2010	37
11	Selective ETAAntagonists. 5. Discovery and Structure−Activity Relationships of Phenoxyphenylacetic Acid Derivatives Journal of Medicinal Chemistry ·Peter C. Astles, Thomas J. Brown, Frank Halley, Caroline M. Handscombe, Neil V. Harris, Tahir N. Majid, Clive McCarthy, Iain M. McLay	2000	35
12	Adenosine receptor ligands as potential therapeutics in asthma. PubMed ·John R. Fozard, Clive McCarthy	2002	35
13	Solubility-Driven Optimization of Phosphodiesterase-4 Inhibitors Leading to a Clinical Candidate Journal of Medicinal Chemistry ·Neil J. Press, Roger Taylor, Joseph D. Fullerton, PAMELA R. TRANTER, Clive McCarthy, Thomas H. Keller, Nicola Arnold, David Beer	2012	32
14	A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential Bioorganic & Medicinal Chemistry Letters ·Neil J. Press, Roger Taylor, Joseph D. Fullerton, PAMELA R. TRANTER, Clive McCarthy, Thomas H. Keller, Lyndon Brown, Robert Cheung	2005	29
15	Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of βII tryptase Bioorganic & Medicinal Chemistry ·Julian R. Levell, Peter C. Astles, Paul R. Eastwood, Jennifer A. Cairns, Olivier Houille, Suzanne C. Aldous, Gregory H. Merriman, Brian J. Whiteley	2005	27
16	A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β2-adrenoceptor agonists as inhaled long-acting bronchodilators Bioorganic & Medicinal Chemistry Letters ·Michelle E. Bradley, Andrew Brearley, Steven J. Charlton, Bernard M. Cuenoud, Robin A. Fairhurst, Peter Gedeck, Martin Gosling, Diana Janus	2010	23
17	Selective Endothelin A Receptor Antagonists. 3. Discovery and Structure−Activity Relationships of a Series of 4-Phenoxybutanoic Acid Derivatives Journal of Medicinal Chemistry ·Peter C. Astles, CLIVE J. BREALEY, Thomas J. Brown, Vincenzo Facchini, Caroline M. Handscombe, Neil V. Harris, Clive McCarthy, Iain M. McLay	1998	21
18	An Efficient Synthesis of Nitroalkenes by Alkene Cross Metathesis: Facile Access to Small Ring Systems Organic Letters ·Graham P. Marsh, Philip J. Parsons, Clive McCarthy, Xavier G. Corniquet	2007	19
19	Tropomyosin receptor kinase inhibitors: a patent update 2009 – 2013 Expert Opinion on Therapeutic Patents ·Clive McCarthy, Edward R. H. Walker	2014	19
20	New non peptidic C5a receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Peter C. Astles, Thomas J. Brown, Frank Halley, Peter M. Lockey, Clive McCarthy, Iain M. McLay, Tahir N. Majid, Andrew Morley	1997	17

About Clive McCarthy

Clive McCarthy is a scholar working on Organic Chemistry, Physiology, Molecular Biology, Physiology and Immunology, having authored 31 papers that have together received 902 indexed citations. Recurring topics across this work include Nitric Oxide and Endothelin Effects (5 papers), Synthesis and biological activity (5 papers), Receptor Mechanisms and Signaling (3 papers), Cystic Fibrosis Research Advances (3 papers), Alzheimer's disease research and treatments (2 papers), Mast cells and histamine (2 papers), Adenosine and Purinergic Signaling (2 papers) and PI3K/AKT/mTOR signaling in cancer (2 papers). The work is most often cited by research in Physiology (50 citations), Organic Chemistry (343 citations), Computational Theory and Mathematics (90 citations), Pulmonary and Respiratory Medicine (135 citations) and Physiology (98 citations). Clive McCarthy has collaborated with scholars based in Switzerland, United Kingdom and United States. Frequent co-authors include Keith A. Jones, John R. Fozard, John M. D. Storey, Martin Gosling, Henry L. Danahay, Andrew J. Clark, Pascal Furet, Peter Drueckes, Ulf Neumann and Jean‐Michel Rondeau. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of Cystic Fibrosis, Tetrahedron Letters and European Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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