Peter C. Astles

765 citations

31 papers · 555 · h-index 15

Impact in

Organic Chemistry top 10%
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
Biotechnology top 10%
- Marine Sponges and Natural Products

Papers in

Molecular Biology 15
- Receptor Mechanisms and Signaling 6
- Nicotinic Acetylcholine Receptors Study 6
- Pharmacological Receptor Mechanisms and Effects 3
Organic Chemistry 10
- Synthetic Organic Chemistry Methods 7
- Asymmetric Synthesis and Catalysis 4

Co-authors: Leo A. Paquette (4 shared papers)Christopher M. Rayner (1 shared paper)Ruud Zwart (4 shared papers)Emanuele Sher (4 shared papers)Paul R. Blakemore (3 shared papers)Neil R. Norcross (3 shared papers)C.A. Kilner (2 shared papers)Eric J. Thomas (1 shared paper)
Journals: Journal of Medicinal Chemistry (7 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Synlett (2 papers)The Journal of Organic Chemistry (2 papers)Molecular Pharmacology (1 paper)
Partner nations: United Kingdom United States Australia

In The Last Decade

Peter C. Astles

31 papers receiving 537 citations

Peers

Countries citing papers authored by Peter C. Astles

Since Specialization

Citations

This map shows the geographic impact of Peter C. Astles's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter C. Astles with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter C. Astles more than expected).

Fields of papers citing papers by Peter C. Astles

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter C. Astles. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter C. Astles. The network helps show where Peter C. Astles may publish in the future.

Co-authors

The 25 scholars most cited alongside Peter C. Astles, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Peter C. Astles Line = papers co-authored together Peter C. Astles links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 31 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Total synthesis of furanocembranolides. 3. A concise convergent route to acerosolide The Journal of Organic Chemistry ·Leo A. Paquette, Peter C. Astles	1993	54
2	Total synthesis of furanocembranolides. 2. Macrocyclization studies culminating in the synthesis of a dihydropseudopterolide and gorgiacerone. Related furanocembranolide interconversions. Journal of the American Chemical Society ·Christopher M. Rayner, Peter C. Astles, Leo A. Paquette	1992	50
3	Selective Cannabinoid Receptor Type 2 (CB2) Agonists: Optimization of a Series of Purines Leading to the Identification of a Clinical Candidate for the Treatment of Osteoarthritic Pain Journal of Medicinal Chemistry ·Sean P. Hollinshead, Michael Tidwell, John R. Palmer, Rossella Guidetti, Adam J. Sanderson, Michael P. Johnson, M.G. Chambers, J.L. Oskins, Robert E. Stratford, Peter C. Astles	2013	42
4	Species Selectivity of a Nicotinic Acetylcholine Receptor Agonist Is Conferred by Two Adjacent Extracellular β4 Amino Acids that Are Implicated in the Coupling of Binding to Channel Gating Molecular Pharmacology ·Gareth T. Young, Lisa M. Broad, Ruud Zwart, Peter C. Astles, Michael J. Bodkin, Emanuele Sher, Neil S. Millar	2006	40
5	Recent Progress in the Development of Subtype Selective Nicotinic Acetylcholine Receptor Ligands PubMed ·Peter C. Astles, Stephen Baker, J.R. Boot, L.M. Broad, C. P. Dell, Martine Keenan	2002	39
6	Total Synthesis of (±)-α-Isosparteine, (±)-β-Isosparteine, and (±)-Sparteine from a Common Tetraoxobispidine Intermediate The Journal of Organic Chemistry ·Neil R. Norcross, J.P. Melbardis, M.F. Solera, Mark A. Sephton, C.A. Kilner, Lev N. Zakharov, Peter C. Astles, Stuart L. Warriner, Paul R. Blakemore	2008	37
7	Selective ET_AAntagonists. 5. Discovery and Structure−Activity Relationships of Phenoxyphenylacetic Acid Derivatives Journal of Medicinal Chemistry ·Peter C. Astles, Thomas J. Brown, Frank Halley, Caroline M. Handscombe, Neil V. Harris, Tahir Majid, Clive McCarthy, Iain M. McLay, Andrew Morley, Barry Porter, Alan G. Roach, Carol A. Sargent, Christopher Smith, R. J. A. WALSH	2000	32
8	The effect of acidosis on the relationship between Ca2+ and force in isolated ferret cardiac muscle. The Journal of Physiology ·Clive H. Orchard, Duncan Hamilton, Peter C. Astles, Eileen McCall, B. R. Jewell	1991	24
9	A Practical Synthesis of (±)-α-Isosparteine from a Tetraoxobispidine Core Organic Letters ·Paul R. Blakemore, C.A. Kilner, Neil R. Norcross, Peter C. Astles	2005	24
10	Unique pharmacology of heteromeric α7β2 nicotinic acetylcholine receptors expressed in Xenopus laevis oocytes European Journal of Pharmacology ·Ruud Zwart, Merrick Strotton, Jennifer Ching, Peter C. Astles, Emanuele Sher	2014	23
11	Syntheses of thunbergols and α- and β-cembra-2,7,11-triene-4,6-diols Journal of the Chemical Society Perkin Transactions 1 ·Peter C. Astles, Eric J. Thomas	1997	18
12	Selective alpha7 nicotinic receptor agents for the treatment of neuropsychiatric diseases Drugs of the Future ·L.M. Broad, Emanuele Sher, Peter C. Astles, Ruud Zwart, M.J. O'Neill	2007	18
13	Selective Endothelin A Receptor Antagonists. 3. Discovery and Structure−Activity Relationships of a Series of 4-Phenoxybutanoic Acid Derivatives Journal of Medicinal Chemistry ·Peter C. Astles, Clive Brealey, Thomas J. Brown, Vincenzo Facchini, Caroline M. Handscombe, Neil V. Harris, Clive McCarthy, Iain M. McLay, Barry Porter, Alan G. Roach, Carol A. Sargent, Christopher Smith, R. J. A. WALSH	1998	17
14	New non peptidic C5a receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Peter C. Astles, Thomas J. Brown, Paul Alan Cox, Frank Halley, Peter Lockey, Clive McCarthy, Iain M. McLay, Tahir Majid, Andrew Morley, Barry Porter, Andrew J. Ratcliffe, R. J. A. WALSH	1997	17
15	Discovery and optimization of novel purines as potent and selective CB2 agonists Bioorganic & Medicinal Chemistry Letters ·Sean P. Hollinshead, Peter C. Astles, M.G. Chambers, Michael P. Johnson, John R. Palmer, Michael Tidwell	2012	15
16	Acyl-CoA:CholesterolO-Acyltransferase (ACAT) Inhibitors. 2. 2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1H-imidazoles as Potent Inhibitors of ACAT Journal of Medicinal Chemistry ·Peter C. Astles, Michael J. Ashton, Andrew W. Bridge, Neil V. Harris, Terrance W. Hart, David P. Parrott, Barry Porter, David Riddell, Christopher Smith, Robert J. Williams	1996	14
17	Selective Endothelin A Receptor Antagonists. 4. Discovery and Structure−Activity Relationships of Stilbene Acid and Alcohol Derivatives Journal of Medicinal Chemistry ·Peter C. Astles, Thomas J. Brown, Frank Halley, Caroline M. Handscombe, Neil V. Harris, Clive McCarthy, Iain M. McLay, Peter Lockey, Tahir Majid, Barry Porter, Alan G. Roach, Christopher Smith, R. J. A. WALSH	1998	12
18	Total Synthesis of (±)-Acerosolide Synlett ·Peter C. Astles, Leo A. Paquette	1992	11
19	Diamine containing VLA-4 antagonists Bioorganic & Medicinal Chemistry ·Peter C. Astles, Neil V. Harris, Andrew Morley	2001	11
20	Selective endothelin A receptor antagonists. 2. Discovery and structure-activity relationships of 5-ketopentanoic acid derivatives European Journal of Medicinal Chemistry ·Peter C. Astles, Thomas J. Brown, Neil V. Harris, Mark F. Harper, Clive McCarthy, Barry Porter, Christopher Smith, R. J. A. WALSH	1997	9

About Peter C. Astles

Peter C. Astles is a scholar working on Molecular Biology, Organic Chemistry, Physiology, Pharmacology and Biophysics, having authored 31 papers that have together received 555 indexed citations. Recurring topics across this work include Synthetic Organic Chemistry Methods (7 papers), Receptor Mechanisms and Signaling (6 papers), Nicotinic Acetylcholine Receptors Study (6 papers), Nitric Oxide and Endothelin Effects (4 papers), Asymmetric Synthesis and Catalysis (4 papers), Electron Spin Resonance Studies (3 papers), Cannabis and Cannabinoid Research (3 papers) and Pharmacological Receptor Mechanisms and Effects (3 papers). The work is most often cited by research in Organic Chemistry (270 citations), Biotechnology (62 citations), Pharmacology (111 citations), Biochemistry (36 citations) and Molecular Biology (235 citations). Peter C. Astles has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Leo A. Paquette, Christopher M. Rayner, Ruud Zwart, Emanuele Sher, Paul R. Blakemore, Neil R. Norcross, C.A. Kilner, Eric J. Thomas, M.G. Chambers and Barry Porter. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Synlett, The Journal of Organic Chemistry and Molecular Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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