Barbara Leiting

4.7k citations

50 papers · 2.7k · 1 hit paper · h-index 26

Impact in

Cellular and Molecular Neuroscience top 5%
- Neuropeptides and Animal Physiology
Endocrinology, Diabetes and Metabolism top 2%
- Diabetes Treatment and Management

Papers in

Oncology 29
- Peptidase Inhibition and Analysis 28
Molecular Biology 26
- Chemical Synthesis and Analysis 5
- Protein Structure and Dynamics 4
- RNA and protein synthesis mechanisms 3

Co-authors: Nancy A. Thornberry (24 shared papers)Donald W. Nicholson (1 shared paper)Réjean Ruel (1 shared paper)Margarita García‐Calvo (1 shared paper)Erin P. Peterson (1 shared paper)KellyAnn D. Pryor (11 shared papers)Joseph K. Wu (24 shared papers)Frank Marsilio (17 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (21 papers)Analytical Biochemistry (3 papers)Protein Expression and Purification (2 papers)Molecular and Cellular Biology (2 papers)Biochemical Journal (2 papers)
Partner nations: United States Germany Switzerland

In The Last Decade

Barbara Leiting

50 papers receiving 2.6k citations

Barbara Leiting's Hit Papers

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Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors 1998 · 878 citations

Peers

Countries citing papers authored by Barbara Leiting

Since Specialization

Citations

This map shows the geographic impact of Barbara Leiting's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Barbara Leiting with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Barbara Leiting more than expected).

Fields of papers citing papers by Barbara Leiting

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Barbara Leiting. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Barbara Leiting. The network helps show where Barbara Leiting may publish in the future.

Co-authors

The 25 scholars most cited alongside Barbara Leiting, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Barbara Leiting Line = papers co-authored together Barbara Leiting links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 50 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors Journal of Biological Chemistry ·Margarita García‐Calvo, Erin P. Peterson, Barbara Leiting, Réjean Ruel, Donald W. Nicholson, Nancy A. Thornberry Hit paper breakdown →	1998	878
2	High-Level Expression of Soluble Protein inEscherichia coliUsing a His6-Tag and Maltose-Binding-Protein Double-Affinity Fusion System Protein Expression and Purification ·KellyAnn D. Pryor, Barbara Leiting	1997	216
3	Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII Biochemical Journal ·Barbara Leiting, KellyAnn D. Pryor, Joseph K. Wu, Frank Marsilio, Reshma A. Patel, Charles S. Craik, Jonathan A. Ellman, Richard Cummings, Nancy A. Thornberry	2003	158
4	Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Scott D. Edmondson, Lan Wei, Jinyou Xu, Jackie Shang, Shiyao Xu, Jianmei Pang, Ashok Chaudhary, Dennis Dean, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Reshma A. Patel, Sangita B. Patel, Giovanna Scapin, Joseph K. Wu, Maria Beconi, Nancy A. Thornberry, Ann E. Weber	2008	97
5	Support of1H NMR assignments in proteins by biosynthetically directed fractional13C-labeling Journal of Biomolecular NMR ·Thomas Szyperski, Dario Neri, Barbara Leiting, Gottfried Otting, Kurt Wüthrich	1992	88
6	Substituted piperazines as novel dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Linda Brockunier, Jiafang He, Lawrence F. Colwell, Bahanu Habulihaz, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Reshma A. Patel, Yohannes Teffera, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber, Emma R. Parmee	2004	77
7	Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 Å resolution Journal of Molecular Biology ·Youwei Yan, Sanjeev Munshi, Barbara Leiting, Matt S. Anderson, J. Chrzas, Zhongguo Chen	2000	71
8	Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7) Biochemical Journal ·Marie-Berthe Maes, Anne‐Marie Lambeir, Kambiz Gilany, Kristel Senten, Pieter Van der Veken, Barbara Leiting, Koen Augustyns, Simon Scharpé, Ingrid De Meester	2005	60
9	Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Jinyou Xu, Lan Wei, Robert J. Mathvink, Jiafang He, You‐Jung Park, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Reshma A. Patel, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber	2005	60
10	Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Jinyou Xu, Hyun Ok, Edward J. Gonzalez, Lawrence F. Colwell, Bahanu Habulihaz, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Reshma A. Patel, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber, Emma R. Parmee	2004	58
11	Dipeptidyl peptidase IV inhibitors derived from β-aminoacylpiperidines bearing a fused thiazole, oxazole, isoxazole, or pyrazole Bioorganic & Medicinal Chemistry Letters ·Wallace T. Ashton, Rosemary M. Sisco, Hong Dong, Kathryn A. Lyons, Huaibing He, George A. Doss, Barbara Leiting, Reshma A. Patel, Joseph K. Wu, Frank Marsilio, Nancy A. Thornberry, Ann E. Weber	2005	54
12	Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Charles G. Caldwell, Ping Chen, Jiafang He, Emma R. Parmee, Barbara Leiting, Frank Marsilio, Reshma A. Patel, Joseph K. Wu, George J. Eiermann, Aleksandr Petrov, Huaibing He, Kathryn A. Lyons, Nancy A. Thornberry, Ann E. Weber	2004	47
13	Predictable Deuteration of Recombinant Proteins Expressed inEscherichia coli Analytical Biochemistry ·Barbara Leiting, Frank Marsilio, John F. O’Connell	1998	44
14	Inhibition of IMP-1 metallo-Î²-lactamase and sensitization of IMP-1-producing bacteria by thioester derivatives FEMS Microbiology Letters ·Gail G. Hammond, Joann Huber, Mark L. Greenlee, Joanne B. Laub, Katherine Young, Lynn L. Silver, James M. Balkovec, KellyAnn D. Pryor, Joseph K. Wu, Barbara Leiting, David L. Pompliano, Jeffrey H. Toney	1999	44
15	Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA™ (sitagliptin phosphate) Bioorganic & Medicinal Chemistry Letters ·Dooseop Kim, Jennifer E. Kowalchick, Scott D. Edmondson, Anthony Mastracchio, Jinyou Xu, George J. Eiermann, Barbara Leiting, Joseph K. Wu, KellyAnn D. Pryor, Reshma A. Patel, Huaibing He, Kathryn A. Lyons, Nancy A. Thornberry, Ann E. Weber	2007	42
16	Potent and selective proline derived dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Scott D. Edmondson, Anthony Mastracchio, Maria Beconi, Lawrence F. Colwell, Bahanu Habulihaz, Huaibing He, Sanjeev Kumar, Barbara Leiting, Kathryn A. Lyons, Ann Mao, Frank Marsilio, Reshma A. Patel, Joseph K. Wu, Lan Zhu, Nancy A. Thornberry, Ann E. Weber, Emma R. Parmee	2004	41
17	(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Bioorganic & Medicinal Chemistry Letters ·Tesfaye Biftu, Dennis Feng, Xiaoxia Qian, Gui‐Bai Liang, G. R. KIECZYKOWSKI, George J. Eiermann, Huaibing He, Barbara Leiting, Kathy Lyons, Aleksandr Petrov, Ranabir SinhaRoy, Bei Zhang, Giovanna Scapin, Sangita Patel, Ying‐Duo Gao, Suresh B. Singh, Joseph K. Wu, Xiaoping Zhang, Nancy A. Thornberry, Ann E. Weber	2006	38
18	Discovery of potent and selective orally bioavailable β-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Scott D. Edmondson, Anthony Mastracchio, Joseph Duffy, George J. Eiermann, Huaibing He, Ida E. Ita, Barbara Leiting, Joseph F. Leone, Kathryn A. Lyons, Amanda M. Makarewicz, Reshma A. Patel, Aleksandr Petrov, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber	2005	38
19	4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors Bioorganic & Medicinal Chemistry Letters ·Emma R. Parmee, Jiafang He, Anthony Mastracchio, Scott D. Edmondson, Larry Colwell, George J. Eiermann, William P. Feeney, Bahanu Habulihaz, Huaibing He, Ruth Kilburn, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Reshma A. Patel, Aleksandr Petrov, Jerry Di Salvo, Joseph K. Wu, Nancy A. Thornberry, Ann E. Weber	2003	37
20	Engineering a Cell-Free Murein Biosynthetic Pathway: Combinatorial Enzymology in Drug Discovery Journal of the American Chemical Society ·Kenny K. Wong, David Kuo, Renee M. Chabin, Carole Fournier, Laura D. Gegnas, Sherman T. Waddell, Frank Marsilio, Barbara Leiting, David L. Pompliano	1998	35

About Barbara Leiting

Barbara Leiting is a scholar working on Oncology, Molecular Biology, Cellular and Molecular Neuroscience, Endocrinology, Diabetes and Metabolism and Materials Chemistry, having authored 50 papers that have together received 2.7k indexed citations. Recurring topics across this work include Peptidase Inhibition and Analysis (28 papers), Neuropeptides and Animal Physiology (24 papers), Diabetes Treatment and Management (20 papers), Enzyme Structure and Function (8 papers), Bacterial Genetics and Biotechnology (6 papers), Chemical Synthesis and Analysis (5 papers), Protein Structure and Dynamics (4 papers) and RNA and protein synthesis mechanisms (3 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (507 citations), Endocrinology, Diabetes and Metabolism (429 citations), Oncology (693 citations), Pharmaceutical Science (138 citations) and Molecular Biology (1.5k citations). Barbara Leiting has collaborated with scholars based in United States, Germany and Switzerland. Frequent co-authors include Nancy A. Thornberry, Donald W. Nicholson, Réjean Ruel, Margarita García‐Calvo, Erin P. Peterson, KellyAnn D. Pryor, Joseph K. Wu, Frank Marsilio, Reshma A. Patel and Ann E. Weber. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Analytical Biochemistry, Protein Expression and Purification, Molecular and Cellular Biology and Biochemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Barbara Leiting

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Barbara Leiting

Barbara Leiting's Hit Papers

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About Barbara Leiting

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