Anne E. Bygrave

4.3k citations

19 papers · 3.6k · 1 hit paper · h-index 18

Impact in

Immunology top 1%
- Complement system in diseases
- T-cell and B-cell Immunology
- Phagocytosis and Immune Regulation
- Immune Cell Function and Interaction
Nephrology top 1%
- Renal Diseases and Glomerulopathies

Papers in

Immunology 13
- Complement system in diseases 8
- T-cell and B-cell Immunology 4
- Immunotherapy and Immune Responses 2
Nephrology 4
- Renal Diseases and Glomerulopathies 4

Co-authors: Mark J. Walport (14 shared papers)H. Terence Cook (6 shared papers)Pier Paolo Pandolfi (3 shared papers)Marina Botto (12 shared papers)Marina Botto (3 shared papers)Michael A. Loos (1 shared paper)Franz Michael Petry (1 shared paper)E. Mary Thompson (1 shared paper)
Journals: The Journal of Immunology (3 papers)Nature Genetics (2 papers)Nature Medicine (1 paper)Nature (1 paper)Molecular Immunology (1 paper)
Partner nations: United Kingdom Netherlands United States

In The Last Decade

Anne E. Bygrave

19 papers receiving 3.5k citations

Anne E. Bygrave's Hit Papers

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Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies 1998 · 1.3k citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

1998 Nature Genetics

Peers

Countries citing papers authored by Anne E. Bygrave

Since Specialization

Citations

This map shows the geographic impact of Anne E. Bygrave's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Anne E. Bygrave with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Anne E. Bygrave more than expected).

Fields of papers citing papers by Anne E. Bygrave

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Anne E. Bygrave. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Anne E. Bygrave. The network helps show where Anne E. Bygrave may publish in the future.

Co-authors

The 25 scholars most cited alongside Anne E. Bygrave, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Anne E. Bygrave Line = papers co-authored together Anne E. Bygrave links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies Nature Genetics ·Marina Botto, Chiara Dell' Agnola, Anne E. Bygrave, E. Mary Thompson, H. Terence Cook, Franz Michael Petry, Michael A. Loos, Pier Paolo Pandolfi, Mark J. Walport Hit paper breakdown →	1998	1256
2	Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene Nature ·Beatriz Nuez, (unknown), Anne E. Bygrave, Rob E. Ploemacher, Frank G. Grosveld	1995	496
3	Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H Nature Genetics ·Matthew Caleb Pickering, H. Terence Cook, Joanna Warren, Anne E. Bygrave, Jill Moss, Mark J. Walport, Marina Botto	2002	437
4	Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene Nature Medicine ·Marina Botto, Philip Nigel Hawkins, Maria C. M. Bickerstaff, Jeff Herbert, Anne E. Bygrave, Alan J. A. McBride, Winston L. Hutchinson, Glenys A. Tennent, Mark J. Walport, Mark B. Pepys	1997	215
5	Spontaneous Autoimmunity in 129 and C57BL/6 Mice—Implications for Autoimmunity Described in Gene-Targeted Mice PLoS Biology ·Anne E. Bygrave, Kirsten L. Rose, Josefina Cortés-Hernández, Joanna Warren, Robert J. Rigby, H. Terence Cook, Mark J. Walport, Timothy Vyse, Marina Botto	2004	158
6	The chromosome make-up of mouse embryonic stem cells is predictive of somatic and germ cell chimaerism Transgenic Research ·Letizia Longo, Anne E. Bygrave, Frank G. Grosveld, Pier Paolo Pandolfi	1997	144
7	Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria Blood ·Dewi S. Holt, Marina Botto, Anne E. Bygrave, S. M. Hanna, Mark J. Walport, B. Paul Morgan	2001	132
8	Murine CD93 (C1qRp) Contributes to the Removal of Apoptotic Cells In Vivo but Is Not Required for C1q-Mediated Enhancement of Phagocytosis The Journal of Immunology ·Peter J. Norsworthy, Liliane Fossati‐Jimack, Josefina Cortés-Hernández, Philip R. Taylor, Anne E. Bygrave, Richard Damian Thompson, Sussan Nourshargh, Mark J. Walport, Marina Botto	2004	124
9	Factor I is required for the development of membranoproliferative glomerulonephritis in factor H–deficient mice Journal of Clinical Investigation ·Kirsten L. Rose, Danielle Paixão-Cavalcante, Jennifer Fish, Anthony P. Manderson, Talat H. Malik, Anne E. Bygrave, Tao Lin, Sacks Steven, Mark J. Walport, H. Terence Cook, Marina Botto, Matthew Caleb Pickering	2008	119
10	Fmrl Knockout Mice: A Model to Study Fragile X Mental Retardation The Dutch-Belgian Fragile X Consortium* Cathy E. Bakker, Coleta Verheij, Rob Willemsen, Robert Van Der Helm, Frank T. J. J. Oerlemans, Marcel Vermey, Anne E. Bygrave, A. T. Hoogeveen, Ben A. Oostra, Edwin Reyniers, Kristel De Boule, Rudi D’Hooge, Patrick P Cras, Désiré Van Velzen, Guy Nagels, Jean‐Jacques Martin, Peter Paul De Deyn, John K. Darby, Patrick J. Willems	1994	102
11	Cutting Edge: C1q Protects Against the Development of Glomerulonephritis Independently of C3 Activation The Journal of Immunology ·Daniel A. J. Mitchell, Philip R. Taylor, H. Terence Cook, Jill Moss, Anne E. Bygrave, Mark J. Walport, Marina Botto	1999	77
12	Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice Molecular Immunology ·Kirsten L. Rose, Danielle Paixão-Cavalcante, Jennifer Fish, Anthony P. Manderson, Talat H. Malik, Anne E. Bygrave, Tao Lin, Sacks Steven, Mark J. Walport, H. Terence Cook, Marina Botto, Matthew Caleb Pickering	2007	73
13	A Targeted Disruption of the Murine Complement Factor B Gene Resulting in Loss of Expression of Three Genes in Close Proximity, Factor B, C2, and D17H6S45 Journal of Biological Chemistry ·Philip R. Taylor, Julian T. Nash, Efstathios Theodoridis, Anne E. Bygrave, Mark J. Walport, Marina Botto	1998	55
14	Genetic Dissection of Spontaneous Autoimmunity Driven by 129-Derived Chromosome 1 Loci When Expressed on C57BL/6 Mice The Journal of Immunology ·Francesco Carlucci, Josefina Cortés-Hernández, Liliane Fossati‐Jimack, Anne E. Bygrave, Mark J. Walport, Timothy Vyse, H. Terence Cook, Marina Botto	2007	55
15	A Role for PML in Innate Immunity Genes & Cancer ·Andrea Lunardi, Mirella Piera Gaboli, Marco Giorgio, Roberta Rivi, Anne E. Bygrave, Michael Nicolas Antoniou, Dubravka Drabek, Elaine Anne Dzierzak, Matteo Fagioli, Leonardo Salmena, Marina Botto, Carlos Cordon‐Cardo, Lucio Luzzatto, Pier Giuseppe Pelicci, Frank G. Grosveld, Pier Paolo Pandolfi	2011	43
16	Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice European Journal of Immunology ·Mohini Perraudeau, Philip R. Taylor, Hans Stauß, Ragnar Lindstedt, Anne E. Bygrave, Darryl J Pappin, Stéphan Ellmerich, Angela Whitten, Dinah Rahman, Benito Cañas, Mark J. Walport, Marina Botto, Daniel Martin Altmann	2000	41
17	Tissue-specific expression of the human type II collagen gene in mice. Proceedings of the National Academy of Sciences ·Robin Howard Lovell-Badge, Anne E. Bygrave, Allan Bradley, Elizabeth J. Robertson, Rita Tilly, Kathryn S.E. Cheah	1987	39
18	Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus Genes and Immunity ·Yasin Heidari, Anne E. Bygrave, Robert J. Rigby, Kamala Rose, Mark J. Walport, H. Terence Cook, Timothy Vyse, Marina Botto	2006	33
19	Knocking out mouse CD59 using a PCR derived gene targeting vector Immunopharmacology ·Dewi S. Holt, Marina Botto, Anne E. Bygrave, Neil K. Rushmere, Mark J. Walport, B. Paul Morgan	2000	2

About Anne E. Bygrave

Anne E. Bygrave is a scholar working on Immunology, Nephrology, Hematology, Genetics and Rheumatology, having authored 19 papers that have together received 3.6k indexed citations. Recurring topics across this work include Complement system in diseases (8 papers), Renal Diseases and Glomerulopathies (4 papers), T-cell and B-cell Immunology (4 papers), Animal Genetics and Reproduction (3 papers), Platelet Disorders and Treatments (3 papers), Pluripotent Stem Cells Research (2 papers), Blood groups and transfusion (2 papers) and Immunotherapy and Immune Responses (2 papers). The work is most often cited by research in Immunology (2.2k citations), Nephrology (495 citations), Hematology (463 citations), Rheumatology (478 citations) and Genetics (324 citations). Anne E. Bygrave has collaborated with scholars based in United Kingdom, Netherlands and United States. Frequent co-authors include Mark J. Walport, H. Terence Cook, Pier Paolo Pandolfi, Marina Botto, Marina Botto, Michael A. Loos, Franz Michael Petry, E. Mary Thompson, Frank G. Grosveld and Beatriz Nuez. Their work appears in journals such as The Journal of Immunology, Nature Genetics, Nature Medicine, Nature and Molecular Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Anne E. Bygrave

Anne E. Bygrave's Hit Papers

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