Ann Chen

5.9k citations

131 papers · 4.9k · 1 hit paper · h-index 41

Impact in

Nephrology top 1%
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Acute Kidney Injury Research
Rheumatology top 2%
- Systemic Lupus Erythematosus Research

Papers in

Nephrology 48
- Renal Diseases and Glomerulopathies 37
- Chronic Kidney Disease and Diabetes 6
- Acute Kidney Injury Research 3
Rheumatology 18
- Systemic Lupus Erythematosus Research 14

Co-authors: Shuk‐Man Ka (54 shared papers)Kuo‐Feng Hua (32 shared papers)Pei‐Yi Tsai (8 shared papers)Hao‐Ai Shui (10 shared papers)Lai‐Fa Sheu (12 shared papers)Chen‐Lung Ho (8 shared papers)Louis Kuoping Chao (7 shared papers)Jia‐Ming Chang (6 shared papers)
Journals: PLoS ONE (6 papers)Scientific Reports (5 papers)The Nephron journals/Nephron journals (5 papers)Free Radical Biology and Medicine (5 papers)Kidney International (4 papers)
Partner nations: Taiwan United States Japan

In The Last Decade

Ann Chen

125 papers receiving 4.8k citations

Ann Chen's Hit Papers

align trajectories log scale

Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses 2022 · 133 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2022 Cancer Cell

Peers

Countries citing papers authored by Ann Chen

Since Specialization

Citations

This map shows the geographic impact of Ann Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ann Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ann Chen more than expected).

Fields of papers citing papers by Ann Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ann Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ann Chen. The network helps show where Ann Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Ann Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ann Chen Line = papers co-authored together Ann Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 131 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 Nature Genetics ·Ellen L. Goode, Georgia Chenevix‐Trench, Honglin Song, Susan J. Ramus, Maria Notaridou, Kate Lawrenson, Martin Widschwendter, Robert Alan Vierkant	2010	297
2	Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation Free Radical Biology and Medicine ·Pei‐Yi Tsai, Shuk‐Man Ka, Jia‐Ming Chang, Hsiang‐Cheng Chen, Hao‐Ai Shui, Chenyun Li, Kuo‐Feng Hua, Wen-Liang Chang	2011	242
3	Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy Journal of Cellular Physiology ·Shuk‐Man Ka, Wan‐Han Hsu, Ann Chen, Louis Kuoping Chao, Chai-Ching Lin, Cho-Chen Hsieh, Ming‐Cheng Chen, Huan-Wen Chiu	2014	193
4	IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis Journal of the American Society of Nephrology ·Hsi-Hua Chi, Kuo‐Feng Hua, Yu‐Chuan Lin, Ching‐Liang Chu, Chih‐Yu Hsieh, Yu‐Juei Hsu, Shuk‐Man Ka, Yu‐Ling Tsai	2017	140
5	Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses Cancer Cell ·Jay K. Mandula, Shiun Chang, Eslam T. Mohamed, Rosa A. Sierra-Mondragon, Darwin Chang, Alyssa Obermayer, Carlos Moran Segura, Julio Angel Vázquez-Martínez Hit paper breakdown →	2022	133
6	Impaired phosphorylation of Na + -K + -2Cl − cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome Proceedings of the National Academy of Sciences ·Shih‐Hua Lin, I‐Shing Yu, Si‐Tse Jiang, Shu‐Wha Lin, Pauling Chu, Ann Chen, Huey‐Kang Sytwu, Eisei Sohara	2011	123
7	Cyclooxygenase‐2 Regulates NLRP3 Inflammasome‐Derived IL‐1β Production Journal of Cellular Physiology ·Kuo‐Feng Hua, Ju‐Ching Chou, Shuk‐Man Ka, Yu‐Ling Tasi, Ann Chen, Shih‐Hsiung Wu, Hsiao‐Wen Chiu, Wei-Ting Wong	2014	121
8	Melatonin prevents endotoxin‐induced circulatory failure in rats Journal of Pineal Research ·Chin‐Chen Wu, Chin‐Wei Chiao, George Hsiao, Ann Chen, Mao‐Hsiung Yen	2001	113
9	Smad7 Gene Therapy Ameliorates an Autoimmune Crescentic Glomerulonephritis in Mice Journal of the American Society of Nephrology ·Shuk‐Man Ka, Xiao‐Ru Huang, Pei‐Yi Tsai, Shun‐Min Yang, Hao‐Ai Shui, Ann Chen +1 other	2007	108
10	Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis Diabetologia ·Shun-Min Yang, Shuk‐Man Ka, Hua‐Lin Wu, Yu-Chuan Yeh, Cheng‐Hsiang Kuo, Kuo‐Feng Hua, Guey-Yueh Shi, Yi-Jen Hung	2013	103
11	Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation Arthritis Research & Therapy ·Shuk‐Man Ka, Jung‐Chen Lin, Tsai-Jung Lin, Feng‐Cheng Liu, Louis Kuoping Chao, Chen‐Lung Ho, Li‐Tzu Yeh, Huey‐Kang Sytwu	2015	95
12	Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion Inflammation Research ·Pei‐Chun Liao, Louis Kuoping Chao, Ju‐Ching Chou, Wei-Chih Dong, Chien-Nan Lin, Chai-Yi Lin, Ann Chen, Shuk‐Man Ka	2012	90
13	Quercetin induced cell apoptosis and altered gene expression in AGS human gastric cancer cells Environmental Toxicology ·Hung‐Sheng Shang, Hsu‐Feng Lu, Ching‐Hsiao Lee, Han‐Sun Chiang, Yung‐Lin Chu, Ann Chen, Yuh‐Feng Lin, Jing‐Gung Chung	2018	87
14	Pathogenesis of IgA nephropathy: In vitro activation of human mesangial cells by IgA immune complex leads to cytokine secretion The Journal of Pathology ·Ann Chen, Wei‐Perng Chen, Lai‐Fa Sheu, Ching‐Yuang Lin	1994	83
15	Resveratrol increases anti-aging Klotho gene expression via the activating transcription factor 3/c-Jun complex-mediated signaling pathway The International Journal of Biochemistry & Cell Biology ·Shih‐Ming Huang, Ann Chen, Chiao-Yin Sun, Shih‐Hua Lin, Jin‐Shuen Chen, Shuting Liu, Yu‐Juei Hsu +1 other	2014	83
16	Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome Free Radical Biology and Medicine ·Shun-Min Yang, Shuk‐Man Ka, Kuo‐Feng Hua, Tzu‐Hua Wu, Yi-Ping Chuang, Ya‐Wen Lin, Feng-Ling Yang, Shih‐Hsiung Wu	2013	77
17	EFFECTS OF A MEMBRANE-PERMEABLE RADICAL SCAVENGER, TEMPOL, ON INTRAPERITONEAL SEPSIS-INDUCED ORGAN INJURY IN RATS Shock ·Wen‐Jinn Liaw, Tai‐Hao Chen, Zheng-Zong Lai, Shiu-Jen Chen, Ann Chen, Chin Tzao, Jeng‐Yuan Wu, Chin‐Chen Wu	2004	76
18	Osthole Mitigates Progressive IgA Nephropathy by Inhibiting Reactive Oxygen Species Generation and NF-κB/NLRP3 Pathway PLoS ONE ·Kuo‐Feng Hua, Shun‐Min Yang, Tzu-Yang Kao, Jia‐Ming Chang, Hui‐Ling Chen, Yung-Jen Tsai, Ann Chen, Sung‐Sen Yang	2013	76
19	BMP‐2 modulates β‐catenin signaling through stimulation of Lrp5 expression and inhibition of β‐TrCP expression in osteoblasts Journal of Cellular Biochemistry ·Ming Zhang, Ying Yan, Yong‐bin Lim, Dezhi Tang, Rong Xie, Ann Chen, Stephen E. Harris, Lianping Xing	2009	72
20	Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice Free Radical Biology and Medicine ·Pei‐Yi Tsai, Shuk‐Man Ka, Tai‐Kuang Chao, Jia‐Ming Chang, Shih‐Hua Lin, Chenyun Li, Mao-Tien Kuo, Peini Chen	2011	72

About Ann Chen

Ann Chen is a scholar working on Nephrology, Rheumatology, Molecular Biology, Reproductive Medicine and Immunology, having authored 131 papers that have together received 4.9k indexed citations. Recurring topics across this work include Renal Diseases and Glomerulopathies (37 papers), Inflammasome and immune disorders (15 papers), Systemic Lupus Erythematosus Research (14 papers), Sepsis Diagnosis and Treatment (7 papers), Chronic Kidney Disease and Diabetes (6 papers), Protein Kinase Regulation and GTPase Signaling (4 papers), Acute Kidney Injury Research (3 papers) and Ovarian cancer diagnosis and treatment (3 papers). The work is most often cited by research in Nephrology (1k citations), Rheumatology (335 citations), Molecular Biology (1.5k citations), Geriatrics and Gerontology (79 citations) and Reproductive Medicine (169 citations). Ann Chen has collaborated with scholars based in Taiwan, United States and Japan. Frequent co-authors include Shuk‐Man Ka, Kuo‐Feng Hua, Pei‐Yi Tsai, Hao‐Ai Shui, Lai‐Fa Sheu, Chen‐Lung Ho, Louis Kuoping Chao, Jia‐Ming Chang, Chin‐Chen Wu and Shih‐Hua Lin. Their work appears in journals such as PLoS ONE, Scientific Reports, The Nephron journals/Nephron journals, Free Radical Biology and Medicine and Kidney International.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Ann Chen's Hit Papers

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About Ann Chen

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