William E. Kohlbrenner

2.4k citations

35 papers · 1.9k · h-index 19

Impact in

Virology top 1%
- HIV Research and Treatment
Infectious Diseases top 1%
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions

Papers in

Infectious Diseases 18
- HIV/AIDS drug development and treatment 18
Organic Chemistry 12
- Click Chemistry and Applications 7

Co-authors: Dale J. Kempf (17 shared papers)Daniel W. Norbeck (10 shared papers)Warren M. Kati (14 shared papers)Akhteruzzaman Molla (15 shared papers)Norman E. Wideburg (6 shared papers)Jacob J. Plattner (5 shared papers)Hing L. Sham (8 shared papers)Deborah A. Paul (2 shared papers)
Journals: Biochemical and Biophysical Research Communications (4 papers)Antimicrobial Agents and Chemotherapy (4 papers)Bioorganic & Medicinal Chemistry Letters (4 papers)Journal of Medicinal Chemistry (3 papers)Archives of Biochemistry and Biophysics (2 papers)
Partner nations: United States United Kingdom Australia

In The Last Decade

William E. Kohlbrenner

35 papers receiving 1.8k citations

Peers

Countries citing papers authored by William E. Kohlbrenner

Since Specialization

Citations

This map shows the geographic impact of William E. Kohlbrenner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William E. Kohlbrenner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William E. Kohlbrenner more than expected).

Fields of papers citing papers by William E. Kohlbrenner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William E. Kohlbrenner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William E. Kohlbrenner. The network helps show where William E. Kohlbrenner may publish in the future.

Co-authors

The 25 scholars most cited alongside William E. Kohlbrenner, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William E. Kohlbrenner Line = papers co-authored together William E. Kohlbrenner links everyone, so they are left out of the graph.

All Works

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Showing the 20 most-cited of 35 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Design, Activity, and 2.8 Å Crystal Structure of a C ₂ Symmetric Inhibitor Complexed to HIV-1 Protease Science ·John W. Erickson, David J. Neidhart, John H. VanDrie, Dale J. Kempf, Xiu Chun Wang, Daniel W. Norbeck, Jacob J. Plattner, Judith Rittenhouse, Mary C. Turon, Norman E. Wideburg, William E. Kohlbrenner, Robert L. Simmer, Rosalind Helfrich, Deborah A. Paul, Mark F. Knigge	1990	447
2	Structure-based, C2 symmetric inhibitors of HIV protease Journal of Medicinal Chemistry ·Dale J. Kempf, Daniel W. Norbeck, LynnMarie Codacovi, Xiu Chun Wang, William E. Kohlbrenner, Norman E. Wideburg, Deborah A. Paul, Mark F. Knigge, Sudthida Vasavanonda	1990	173
3	Use of a Fluorescence Plate Reader for Measuring Kinetic Parameters with Inner Filter Effect Correction Analytical Biochemistry ·Yaya Liu, Warren M. Kati, Chih‐Ming Chen, Rakesh Tripathi, Akhter Molla, William E. Kohlbrenner	1999	161
4	Human Serum Attenuates the Activity of Protease Inhibitors toward Wild-Type and Mutant Human Immunodeficiency Virus Virology ·Akhteruzzaman Molla, Sudthida Vasavanonda, Gondi Kumar, Hing L. Sham, Marianne K. Johnson, Brian Grabowski, Jon F. Denissen, William E. Kohlbrenner, Jacob J. Plattner, John M. Leonard, Daniel W. Norbeck, Dale J. Kempf	1998	154
5	In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor Journal of Virology ·Alejandro Vicente‐Carrillo, Kent D. Stewart, Hing L. Sham, Daniel W. Norbeck, William E. Kohlbrenner, John M. Leonard, Dale J. Kempf, Akhteruzzaman Molla	1998	136
6	Antibacterial agents specifically inhibiting lipopolysaccharide synthesis Nature ·Robert C. Goldman, William E. Kohlbrenner, Paul A. Lartey, André G. Pernet	1987	122
7	In Vitro Characterization of A-315675, a Highly Potent Inhibitor of A and B Strain Influenza Virus Neuraminidases and Influenza Virus Replication Antimicrobial Agents and Chemotherapy ·Warren M. Kati, Debra Montgomery, Robert J. Carrick, Larisa V. Gubareva, Clarence J. Maring, Keith F. McDaniel, Kevin Steffy, Akhteruzzaman Molla, Frederick G. Hayden, Dale J. Kempf, William E. Kohlbrenner	2002	75
8	New Quinolone Compounds from Pseudonocardia sp. with Selective and Potent Anti-Helicobacter pylori Activity: Taxonomy of Producing Strain, Fermentation, Isolation, Structural Elucidation and Biological Activities. The Journal of Antibiotics ·Koen Dekker, TAISUKE INAGAKI, Thomas D. Gootz, Liang Huang, Yasuhiro Kojima, William E. Kohlbrenner, YASUE MATSUNAGA, Paul R. McGuirk, ETSUKO NOMURA, TATSUO SAKAKIBARA, Shinichi Sakemi, Yumiko Suzuki, Yuji Yamauchi, Nakao Kojima	1998	58
9	Structure-Based Characterization and Optimization of Novel Hydrophobic Binding Interactions in a Series of Pyrrolidine Influenza Neuraminidase Inhibitors Journal of Medicinal Chemistry ·Clarence J. Maring, Vincent S. Stoll, Chen Zhao, Minghua Sun, Allan C. Krueger, Kent D. Stewart, Darold L. Madigan, Warren M. Kati, Yibo Xu, Robert J. Carrick, Debra Montgomery, Anita J. Kempf-Grote, Kennan C. Marsh, Akhteruzzaman Molla, Kevin Steffy, Hing L. Sham, W.G. Laver, Yu‐Gui Gu, Dale J. Kempf, William E. Kohlbrenner	2005	47
10	Synthesis of (2S,5S,4R)-2,5-diamino-3,3-difluoro-1,6-diphenylhydroxyhexane: the core unit of a potent HIV proteinase inhibitor Journal of the Chemical Society Chemical Communications ·Hing L. Sham, Norman E. Wideburg, Stephen G. Spanton, William E. Kohlbrenner, David A. Betebenner, Dale J. Kempf, Daniel W. Norbeck, Jacob J. Plattner, John W. Erickson	1991	45
11	In Vitro Selection and Characterization of Influenza A (A/N9) Virus Variants Resistant to a Novel Neuraminidase Inhibitor, A-315675 Journal of Virology ·Akhteruzzaman Molla, Warren M. Kati, Robert J. Carrick, Kevin Steffy, Yan Shi, Debra Montgomery, Nanette J. Gusick, Vincent S. Stoll, Kent D. Stewart, Teresa I. Ng, Clarence J. Maring, Dale J. Kempf, William E. Kohlbrenner	2002	43
12	Design of orally bioavailable, symmetry-based inhibitors of HIV protease Bioorganic & Medicinal Chemistry ·Dale J. Kempf, Kennan C. Marsh, Lynnmarie Codacovi Fino, P Bryant, Adrienne Craig-Kennard, Hing L. Sham, Chen Zhao, Sudthida Vasavanonda, William E. Kohlbrenner, Norman E. Wideburg, Ayda Saldivar, Brian E. Green, Thomas Herrin, Daniel W. Norbeck	1994	40
13	Activity of a Potent Hepatitis C Virus Polymerase Inhibitor in the Chimpanzee Model Antimicrobial Agents and Chemotherapy ·Chih‐Ming Chen, Yupeng He, Liangjun Lu, Hock Ben Lim, Rakesh Tripathi, Tim Middleton, Lisa E. Hernandez, David W. A. Beno, Michelle A. Long, Warren M. Kati, Todd D. Bosse, Daniel P. Larson, Rolf Wagner, Robert E. Lanford, William E. Kohlbrenner, Dale J. Kempf, (unknown), Akhteruzzaman Molla	2007	39
14	GS4071 Is a Slow-Binding Inhibitor of Influenza Neuraminidase from Both A and B Strains Biochemical and Biophysical Research Communications ·Warren M. Kati, Ayda S. Saldivar, Fariborz Mohamadi, Hing L. Sham, W.G. Laver, William E. Kohlbrenner	1998	39
15	Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction Virology ·Hongmei Mo, Alex K. Konstantinidis, Kent D. Stewart, Tatyana Dekhtyar, Teresa I. Ng, Kerry M. Swift, Edmund D. Matayoshi, Warren M. Kati, William E. Kohlbrenner, Akhteruzzaman Molla	2004	39
16	Inhibitors of HCV NS5B polymerase: synthesis and structure–activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines Bioorganic & Medicinal Chemistry Letters ·John K. Pratt, Pamela Donner, Keith F. McDaniel, Clarence J. Maring, Warren M. Kati, Hongmei Mo, Tim Middleton, Yaya Liu, Teresa I. Ng, Qinghua Xie, Rong Zhang, Debra Montgomery, Akhteruzzaman Molla, Dale J. Kempf, William E. Kohlbrenner	2005	28
17	Novel α- and β-Amino Acid Inhibitors of Influenza Virus Neuraminidase Antimicrobial Agents and Chemotherapy ·Warren M. Kati, Debra Montgomery, Clarence J. Maring, Vincent S. Stoll, Vincent L. Giranda, Xiaoqi Chen, W.G. Laver, William E. Kohlbrenner, Daniel W. Norbeck	2001	27
18	Affinity purification of HIV-1 and HIV-2 proteases from recombinant E. coli strains using pepstatin-agarose Biochemical and Biophysical Research Communications ·Judith Rittenhouse, Mary C. Turon, Rosalind Helfrich, Kathryn S. Albrecht, Debra Weigl, Robert L. Simmer, Federico E. Mordini, John W. Erickson, William E. Kohlbrenner	1990	27
19	Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket Bioorganic & Medicinal Chemistry Letters ·Kent D. Stewart, Jeffrey R. Huth, Teresa I. Ng, Keith F. McDaniel, Rebecca Hutchinson, Vincent S. Stoll, Renaldo Mendoza, Edmund D. Matayoshi, Robert J. Carrick, Hongmei Mo, Jean M. Severin, Karl A. Walter, Paul L. Richardson, Leo W. Barrett, Robert Meadows, (unknown), William E. Kohlbrenner, Clarence J. Maring, Dale J. Kempf, Akhter Molla, Edward T. Olejniczak	2009	26
20	Heteronuclear three-dimensional NMR spectroscopy applied to CMP-KDO synthetase (27.5 kD) Biochemical and Biophysical Research Communications ·Stephen W. Fesik, Robert T. Gampe, Erik R. P. Zuiderweg, William E. Kohlbrenner, Debra Weigl	1989	18

About William E. Kohlbrenner

William E. Kohlbrenner is a scholar working on Infectious Diseases, Organic Chemistry, Molecular Biology, Virology and Epidemiology, having authored 35 papers that have together received 1.9k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (18 papers), HIV Research and Treatment (11 papers), Hepatitis C virus research (8 papers), Click Chemistry and Applications (7 papers), Influenza Virus Research Studies (6 papers), Monoclonal and Polyclonal Antibodies Research (5 papers), Biochemical and Molecular Research (3 papers) and Hepatitis B Virus Studies (2 papers). The work is most often cited by research in Virology (666 citations), Infectious Diseases (915 citations), Hepatology (162 citations), Organic Chemistry (523 citations) and Molecular Biology (764 citations). William E. Kohlbrenner has collaborated with scholars based in United States, United Kingdom and Australia. Frequent co-authors include Dale J. Kempf, Daniel W. Norbeck, Warren M. Kati, Akhteruzzaman Molla, Norman E. Wideburg, Jacob J. Plattner, Hing L. Sham, Deborah A. Paul, Mark F. Knigge and John W. Erickson. Their work appears in journals such as Biochemical and Biophysical Research Communications, Antimicrobial Agents and Chemotherapy, Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry and Archives of Biochemistry and Biophysics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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