John K. Pratt

2.1k citations

23 papers · 717 · h-index 15

Impact in

Hepatology top 5%
- Hepatitis C virus research
Organic Chemistry top 10%
- Synthesis and biological activity
- Catalytic C–H Functionalization Methods

Papers in

Infectious Diseases 8
- HIV/AIDS drug development and treatment 8
Organic Chemistry 8
- Quinazolinone synthesis and applications 4
- Synthesis and Catalytic Reactions 3

Co-authors: Arthur A. Hancock (5 shared papers)Marlon Cowart (4 shared papers)Timothy A. Esbenshade (4 shared papers)William R. Baker (1 shared paper)Steven W. Elmore (3 shared papers)Chun Wel Lin (3 shared papers)Michael J. Coghlan (3 shared papers)Michael A. Stashko (3 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (10 papers)Journal of Medicinal Chemistry (3 papers)Inflammation Research (2 papers)Tetrahedron (1 paper)Antimicrobial Agents and Chemotherapy (1 paper)
Partner nations: United States United Kingdom

In The Last Decade

John K. Pratt

23 papers receiving 690 citations

Peers

Countries citing papers authored by John K. Pratt

Since Specialization

Citations

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Fields of papers citing papers by John K. Pratt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John K. Pratt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John K. Pratt. The network helps show where John K. Pratt may publish in the future.

Co-authors

The 25 scholars most cited alongside John K. Pratt, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John K. Pratt Line = papers co-authored together John K. Pratt links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Nonsteroidal Selective Glucocorticoid Modulators: the Effect of C-5 Alkyl Substitution on the Transcriptional Activation/Repression Profile of 2,5-Dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines Journal of Medicinal Chemistry ·Steven W. Elmore, Michael J. Coghlan, David D. Anderson, John K. Pratt, Brian E. Green, Alan X. Wang, Michael A. Stashko, Chun Wel Lin, Curtis M. Tyree, Jeffery N. Miner, Peer B. Jacobson, Denise M. Wilcox, Benjamin C. Lane	2001	95
2	Nonsteroidal Selective Glucocorticoid Modulators: The Effect of C-10 Substitution on Receptor Selectivity and Functional Potency of 5-Allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines Journal of Medicinal Chemistry ·Philip R. Kym, Michael E. Kort, Michael J. Coghlan, J. L. MOORE, Rui Tang, James D. Ratajczyk, Daniel P. Larson, Steven W. Elmore, John K. Pratt, Michael A. Stashko, H. Douglass Falls, Chun Wel Lin, Masake Nakane, Loan Miller, Curtis M. Tyree, Jeffery N. Miner, Peer B. Jacobson, Denise M. Wilcox, Phong Nguyen, Benjamin C. Lane	2003	88
3	Mutations Conferring Resistance to a Hepatitis C Virus (HCV) RNA-Dependent RNA Polymerase Inhibitor Alone or in Combination with an HCV Serine Protease Inhibitor In Vitro Antimicrobial Agents and Chemotherapy ·Hongmei Mo, Liangjun Lu, (unknown), Ron Pithawalla, Rubina Mondal, Sherie Masse, Tatyana Dekhtyar, Teresa I. Ng, Gennadiy Koev, Vincent S. Stoll, Kent D. Stewart, John K. Pratt, Pam Donner, Todd W. Rockway, Clarence J. Maring, Akhteruzzaman Molla	2005	87
4	A new class of potent non-imidazole H3 antagonists: 2-aminoethylbenzofurans Bioorganic & Medicinal Chemistry Letters ·Marlon Cowart, John K. Pratt, Andrew O. Stewart, Youssef L. Bennani, Timothy A. Esbenshade, Arthur A. Hancock	2003	74
5	Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators Bioorganic & Medicinal Chemistry Letters ·Steven W. Elmore, John K. Pratt, Michael J. Coghlan, Yue Mao, Brian E. Green, David D. Anderson, Michael A. Stashko, Chun Wel Lin, Douglas L. Falls, Masaki Nakane, Loan Miller, Curtis M. Tyree, Jeffrey N. Miner, Ben Lane	2004	42
6	Mechanistic Study of HCV Polymerase Inhibitors at Individual Steps of the Polymerization Reaction Biochemistry ·Yaya Liu, Wen Jiang, John K. Pratt, Todd W. Rockway, Kevin S. Harris, Sudthida Vasavanonda, Rakesh Tripathi, Ron Pithawalla, Warren M. Kati	2006	39
7	Adenosine kinase inhibitors: polar 7-Substitutent of pyridopyrimidine derivatives improving their locomotor selectivity Bioorganic & Medicinal Chemistry Letters ·Guo Zhu Zheng, Yue Mao, Chih‐Hung Lee, John K. Pratt, John R. Koenig, Richard J. Perner, Marlon Cowart, Gregory A. Gfesser, Steve McGaraughty, Katharine L. Chu, Chang Zhu, Haixia Yu, Kathy L. Kohlhaas, Karen M. Alexander, Carol T. Wismer, Joseph P. Mikusa, Michael F. Jarvis, Elizabeth A. Kowaluk, Andrew O. Stewart	2003	34
8	Dipeptide isosteres. 2. Synthesis of hydroxyethylene dipeptide isostere diastereomers from a common γ-lactone intermediate. Preparation of renin and HIV-1 protease inhibitor transition state mimics. Tetrahedron ·William R. Baker, John K. Pratt	1993	31
9	Structure−Activity Studies for a Novel Series of Bicyclic Substituted Hexahydrobenz[e]isoindole α_1A Adrenoceptor Antagonists as Potential Agents for the Symptomatic Treatment of Benign Prostatic Hyperplasia Journal of Medicinal Chemistry ·Michael D. Meyer, Robert J. Altenbach, Hao Bai, Fatima Z. Basha, William A. Carroll, James F. Kerwin, Suzanne A. Lebold, Edmund Lee, John K. Pratt, Kevin B. Sippy, Karin Tietje, Michael Wendt, Michael E. Brune, Steven A. Buckner, Arthur A. Hancock, Irene Drizin	2001	29
10	Inhibitors of HCV NS5B polymerase: synthesis and structure–activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines Bioorganic & Medicinal Chemistry Letters ·John K. Pratt, Pamela Donner, Keith F. McDaniel, Clarence J. Maring, Warren M. Kati, Hongmei Mo, Tim Middleton, Yaya Liu, Teresa I. Ng, Qinghua Xie, Rong Zhang, Debra Montgomery, Akhteruzzaman Molla, Dale J. Kempf, William E. Kohlbrenner	2005	28
11	Inhibitors of HCV NS5B polymerase: Synthesis and structure–activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides Bioorganic & Medicinal Chemistry Letters ·A. Chris Krueger, Darold L. Madigan, Wen Jiang, Warren M. Kati, Dachun Liu, Yaya Liu, Clarence J. Maring, Sherie Masse, Keith F. McDaniel, Tim Middleton, Hongmei Mo, Akhteruzzaman Molla, Debra Montgomery, John K. Pratt, Todd W. Rockway, Rong Zhang, Dale J. Kempf	2006	24
12	In vitro Optimization of Structure Activity Relationships of Analogues of A‐331440 Combining Radioligand Receptor Binding Assays and Micronucleus Assays of Potential Antiobesity Histamine H₃ Receptor Antagonists Basic & Clinical Pharmacology & Toxicology ·Arthur A. Hancock, Marilyn S. Diehl, Ramin Faghih, Eugene N. Bush, Kathleen M. Krueger, G. Krishna, Thomas R. Miller, Denise Madeddu, Wilcox, Phong Nguyen, John K. Pratt, Marlon Cowart, Timothy A. Esbenshade, Peer B. Jacobson	2004	22
13	Inhibitors of HCV NS5B polymerase: Synthesis and structure–activity relationships of N-1-benzyl and N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine analogs containing substituents on the aromatic ring Bioorganic & Medicinal Chemistry Letters ·Todd W. Rockway, Rong Zhang, Dachun Liu, David A. Betebenner, Keith F. McDaniel, John K. Pratt, David W. A. Beno, Debra Montgomery, Wen Jiang, Sherie Masse, Warren M. Kati, Tim Middleton, Akhteruzzaman Molla, Clarence J. Maring, Dale J. Kempf	2006	22
14	Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Irini Akritopoulou‐Zanze, Jyoti Patel, Kresna Hartandi, Jehrod Brenneman, Martin Winn, John K. Pratt, Marlene Grynfarb, Annika Goos‐Nisson, Thomas W von Geldern, Philip R. Kym	2004	20
15	Des-A-ring benzothiadiazines: Inhibitors of HCV genotype 1 NS5B RNA-dependent RNA polymerase Bioorganic & Medicinal Chemistry Letters ·Pamela L. Donner, Qinghua Xie, John K. Pratt, Clarence J. Maring, Warren M. Kati, Wen Jiang, Yaya Liu, Gennadiy Koev, Sherie Masse, Debra Montgomery, Akhter Molla, Dale J. Kempf	2008	16
16	Antiobesity evaluation of histamine H3 receptor (H3R) antagonist analogs of A-331440 with improved safety and efficacy Inflammation Research ·Arthur A. Hancock, Marilyn S. Diehl, Thomas A. Fey, Eugene N. Bush, R. Faghih, Ted R. Miller, K. M. Krueger, John K. Pratt, M. D. Cowart, Robert Dickinson, Robin Shapiro, Victoria Knourek-Segel, Brian A. Droz, Cathleen McDowell, G. Krishna, M.E. Brune, Timothy A. Esbenshade, Peer B. Jacobson	2005	14
17	D‐Amino Acid Homopiperazine Amides: Discovery of A‐320436, a Potent and Selective Non‐Imidazole Histamine H₃‐Receptor Antagonist Archiv der Pharmazie ·Michael P. Curtis, Wesley Dwight, John K. Pratt, Marlon Cowart, Timothy A. Esbenshade, K. M. Krueger, Gerard B. Fox, Jia Bao Pan, Thomas G. Pagano, Arthur A. Hancock, Ramin Faghih, Youssef L. Bennani	2004	13
18	Identification of halosalicylamide derivatives as a novel class of allosteric inhibitors of HCV NS5B polymerase Bioorganic & Medicinal Chemistry Letters ·Yaya Liu, Pamela L. Donner, John K. Pratt, Wen Jiang, Teresa I. Ng, Vijaya Gracias, Steve Baumeister, Paul E. Wiedeman, Linda Traphagen, Usha Warrior, Clarence J. Maring, Warren M. Kati, Stevan W. Djurić, Akhteruzzaman Molla	2008	13
19	5-Membered ring heterocyclic carboxylic acids as angiotensin II antagonists Bioorganic & Medicinal Chemistry Letters ·John K. Pratt, Hwan-Soo Jae, Saul H. Rosenberg, Ken Spina, Martin Winn, Steven A. Buckner, Eugene I. Novosad, Daniel J. Kerkman, Kazumi Shiosaki, Terry J. Opgenorth, Hohn DeBernardis	1994	12
20	The medicinal chemistry of novel H 3 antagonists Inflammation Research ·M. D. Cowart, R. Faghih, Gregory A. Gfesser, Michael A. Curtis, John K. Pratt, Youssef L. Bennani, Gerard B. Fox, T. A. Esbenshade, A. A. Hancock	2004	6

About John K. Pratt

John K. Pratt is a scholar working on Infectious Diseases, Organic Chemistry, Hepatology, Molecular Biology and Immunology, having authored 23 papers that have together received 717 indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (8 papers), Hepatitis C virus research (8 papers), Mast cells and histamine (5 papers), Quinazolinone synthesis and applications (4 papers), Estrogen and related hormone effects (4 papers), Receptor Mechanisms and Signaling (3 papers), Synthesis and Catalytic Reactions (3 papers) and Hepatitis B Virus Studies (2 papers). The work is most often cited by research in Hepatology (183 citations), Organic Chemistry (308 citations), Infectious Diseases (123 citations), Sensory Systems (32 citations) and Immunology (98 citations). John K. Pratt has collaborated with scholars based in United States and United Kingdom. Frequent co-authors include Arthur A. Hancock, Marlon Cowart, Timothy A. Esbenshade, William R. Baker, Steven W. Elmore, Chun Wel Lin, Michael J. Coghlan, Michael A. Stashko, Curtis M. Tyree and Youssef L. Bennani. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Inflammation Research, Tetrahedron and Antimicrobial Agents and Chemotherapy.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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