William C. Ripka

1.4k citations

38 papers · 1.1k · h-index 21

Impact in

Toxicology top 5%
Organic Chemistry top 5%
- Click Chemistry and Applications
- Carbohydrate Chemistry and Synthesis
- Synthesis and Catalytic Reactions

Papers in

Molecular Biology 29
- Chemical Synthesis and Analysis 18
- Cancer-related gene regulation 3
Organic Chemistry 15
- Synthesis and Catalytic Reactions 4
- Carbohydrate Chemistry and Synthesis 3
- Click Chemistry and Applications 3

Co-authors: A. Bach (3 shared papers)Terence K. Brunck (11 shared papers)J. Edward Semple (11 shared papers)Richard S. Pottorf (2 shared papers)George V. De Lucca (2 shared papers)Jeffrey M. Blaney (3 shared papers)Susan Y. Tamura (6 shared papers)Steen B. Mortensen (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Medicinal Chemistry (4 papers)The Journal of Organic Chemistry (3 papers)Tetrahedron (2 papers)Tetrahedron Letters (2 papers)
Partner nations: United States Denmark Sweden

In The Last Decade

William C. Ripka

37 papers receiving 1.0k citations

Peers

Countries citing papers authored by William C. Ripka

Since Specialization

Citations

This map shows the geographic impact of William C. Ripka's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William C. Ripka with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William C. Ripka more than expected).

Fields of papers citing papers by William C. Ripka

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William C. Ripka. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William C. Ripka. The network helps show where William C. Ripka may publish in the future.

Co-authors

The 25 scholars most cited alongside William C. Ripka, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William C. Ripka Line = papers co-authored together William C. Ripka links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 38 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B Journal of Biological Chemistry ·Lars Iversen, Henrik Sune Andersen, Sven Branner, Steen B. Mortensen, Günther H. Peters, Kjeld Norris, Ole H. Olsen, Claus Jeppesen, Behrend F. Lundt, William C. Ripka, Karin Möller, Niels Peter Hundahl Møller	2000	149
2	Discovery and SAR of a Novel Selective and Orally Bioavailable Nonpeptide Classical Competitive Inhibitor Class of Protein-Tyrosine Phosphatase 1B Journal of Medicinal Chemistry ·Henrik Sune Andersen, Ole H. Olsen, Lars Iversen, Anette L. P. Sørensen, Steen B. Mortensen, Michael Christensen, Sven Branner, Thomas K. Hansen, Jesper Lau, Lone Jeppesen, Edmond J. Moran, Jing Su, Farid Bakir, Luke M. Judge, Manou Shahbaz, Tassie L. Collins, Todd Vo, Michael Newman, William C. Ripka, Niels Peter Hundahl Møller	2002	110
3	Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides. Tetrahedron ·William C. Ripka, George V. De Lucca, A. Bach, Richard S. Pottorf, Jeffrey M. Blaney	1993	81
4	Computer modelling of the NAD binding site of ADP‐ribosylating toxins: active‐site structure and mechanism of NAD binding Molecular Microbiology ·Mario Domenighini, Cesare Montecucco, William C. Ripka, Rino Rappuoli	1991	64
5	Design, Synthesis, and Evolution of a Novel, Selective, and Orally Bioavailable Class of Thrombin Inhibitors: P1-Argininal Derivatives Incorporating P3-P4 Lactam Sulfonamide Moieties Journal of Medicinal Chemistry ·J. Edward Semple, David Rowley, Terence K. Brunck, Theresa Ha‐Uong, Nathaniel K. Minami, Timothy D. Owens, Susan Y. Tamura, Erick A. Goldman, Daniel V. Siev, Robert Ardecky, Stephen H. Carpenter, Yu Ge, Brigitte M. Richard, Thomas G. Nolan, Kjell Håkanson, Al Tulinsky, Ruth F. Nutt, William C. Ripka	1996	56
6	Development of Potent Non-Carbohydrate Imidazole-Based Small Molecule Selectin Inhibitors with Antiinflammatory Activity Journal of Medicinal Chemistry ·Deborah H. Slee, Suzanne J. Romano, Jinghua Yu, Truc N. Nguyen, Judy K. John, Neil Raheja, Frank U. Axe, Todd K. Jones, William C. Ripka	2001	53
7	High-throughput purification of compound libraries Drug Discovery Today ·William C. Ripka, G.C. Barker, Jonathan Krakover	2001	43
8	A short and stereospecific synthesis of (±)-α-lycorane Tetrahedron Letters ·Chia‐Lin J. Wang, William C. Ripka, Pat N. Confalone	1984	38
9	Protein β-turn mimetics II: Design, synthesis, and evaluation in the cyclic peptide gramicidin S Tetrahedron ·William C. Ripka, George V. De Lucca, A. Bach, Richard S. Pottorf, Jeffrey M. Blaney	1993	37
10	Inhibition of Fructose-1,6-bisphosphatase by a New Class of Allosteric Effectors Journal of Biological Chemistry ·Jun-Young Choe, Scott W. Nelson, Kristen L. Arienti, Frank U. Axe, Tassie L. Collins, Todd K. Jones, Rachel D.A. Kimmich, Michael Newman, Karl Norvell, William C. Ripka, Suzanne J. Romano, Kevin M. Short, Deborah H. Slee, Herbert J. Fromm, Richard B. Honzatko	2003	35
11	Novel and general method for the preparation of peptidyl argininals Tetrahedron Letters ·Susan Y. Tamura, J. Edward Semple, Robert Ardecky, Pamela Leon, Steven H. Carpenter, Yu Ge, Brian M. Shamblin, Michael I. Weinhouse, William C. Ripka, Ruth F. Nutt	1996	31
12	Synthesis and NMR conformational analysis of a β‐turn mimic incorporated into gramicidin S International journal of peptide & protein research ·A. Bach, Jay A. Markwalder, William C. Ripka	1991	31
13	Characterisation of a Novel Series of Aprotinin-Derived Anticoagulants Thrombosis and Haemostasis ·Jean Marie Stassen, Anne‐Marie Lambeir, G. Matthyssens, William C. Ripka, Åke Nyström, Jan J. Sixma, Jos Vermylen	1995	30
14	Synthesis and biological activity of P2–P4 azapeptidomimetic P1-argininal and P1-ketoargininamide derivatives: a novel class of serine protease inhibitors Bioorganic & Medicinal Chemistry Letters ·J. Edward Semple, David Rowley, Terence K. Brunck, William C. Ripka	1997	29
15	New thrombin inhibitors in cardiovascular disease Current Opinion in Chemical Biology ·William C. Ripka	1997	29
16	Synthesis, structure, and structure‐activity relationships of divalent thrombin inhibitors containing an α‐keto‐amide transition‐state mimetic Protein Science ·Raman Krishnan, A. Tulinsky, George P. Vlasuk, Daniel A. Pearson, Pureza Vallar, Peter W. Bergum, Terence K. Brunck, William C. Ripka	1996	28
17	Synthesis and structure–activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7 Bioorganic & Medicinal Chemistry Letters ·Yi Hu, Lifu Ma, Min Wu, Melissa S. Wong, Bei Li, Sergio Corral, Zhizhou Yu, Tyzoon Nomanbhoy, Senaiet Alemayehu, Stacy R. Fuller, Jonathan S. Rosenblum, Natasha Rozenkrants, Lauro Minimo, William C. Ripka, Anna Katrin Szardenings, John W. Kozarich, Kevin Shreder	2005	28
18	Potent and Selective Thrombin Inhibitors Incorporating the Constrained Arginine Mimic l-3-Piperidyl(N-guanidino)alanine at P₁ Journal of Medicinal Chemistry ·Odile E. Levy, J. Edward Semple, Michael Lim, John Reiner, William E. Rote, E. W. Dempsey, Brigitte M. Richard, Erli Zhang, Al Tulinsky, William C. Ripka, Ruth F. Nutt	1996	27
19	Design and synthesis of a novel class of thrombin inhibitors incorporating heterocyclic dipeptide surrogates Bioorganic & Medicinal Chemistry Letters ·Susan Y. Tamura, J. Edward Semple, John Reiner, Erick A. Goldman, Terence K. Brunck, Marguerita Lim-Wilby, Stephen H. Carpenter, William E. Rote, Gerard L. Oldeshulte, Brigitte M. Richard, Ruth F. Nutt, William C. Ripka	1997	26
20	Rational design, synthesis, and serine protease inhibitory activity of a novel P1-argininal derivative featuring a conformationally constrained P2–P3 bicyclic lactam moiety Bioorganic & Medicinal Chemistry Letters ·Susan Y. Tamura, Erick A. Goldman, Terence K. Brunck, William C. Ripka, J. Edward Semple	1997	22

About William C. Ripka

William C. Ripka is a scholar working on Molecular Biology, Organic Chemistry, Oncology, Hematology and Cellular and Molecular Neuroscience, having authored 38 papers that have together received 1.1k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (18 papers), Peptidase Inhibition and Analysis (11 papers), Blood Coagulation and Thrombosis Mechanisms (5 papers), Synthesis and Catalytic Reactions (4 papers), Carbohydrate Chemistry and Synthesis (3 papers), Click Chemistry and Applications (3 papers), Cancer-related gene regulation (3 papers) and Neuropeptides and Animal Physiology (3 papers). The work is most often cited by research in Toxicology (53 citations), Organic Chemistry (403 citations), Molecular Biology (713 citations), Hematology (110 citations) and Immunology (200 citations). William C. Ripka has collaborated with scholars based in United States, Denmark and Sweden. Frequent co-authors include A. Bach, Terence K. Brunck, J. Edward Semple, Richard S. Pottorf, George V. De Lucca, Jeffrey M. Blaney, Susan Y. Tamura, Steen B. Mortensen, Sven Branner and Henrik Sune Andersen. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, The Journal of Organic Chemistry, Tetrahedron and Tetrahedron Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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William C. Ripka

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