Wayne J. Thompson

2.2k citations

48 papers · 1.7k · h-index 23

Impact in

Virology top 2%
- HIV Research and Treatment
Organic Chemistry top 2%
- Synthetic Organic Chemistry Methods
- Click Chemistry and Applications
- Asymmetric Synthesis and Catalysis
- Carbohydrate Chemistry and Synthesis

Papers in

Organic Chemistry 33
- Click Chemistry and Applications 13
- Carbohydrate Chemistry and Synthesis 7
- Asymmetric Synthesis and Catalysis 6
- Synthesis and Reactivity of Heterocycles 3
Molecular Biology 22
- Chemical Synthesis and Analysis 12

Co-authors: Arun K. Ghosh (16 shared papers)John J. Gaudino (2 shared papers)S. P. MCKEE (15 shared papers)Paul L. Darke (11 shared papers)Paula M.D. Fitzgerald (4 shared papers)Robert E. Ireland (4 shared papers)M. Katharine Holloway (4 shared papers)Joan A. Zugay (8 shared papers)
Journals: Journal of Medicinal Chemistry (13 papers)The Journal of Organic Chemistry (9 papers)Tetrahedron Letters (7 papers)Journal of the American Chemical Society (3 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)
Partner nations: United States Japan

In The Last Decade

Wayne J. Thompson

48 papers receiving 1.6k citations

Peers

Countries citing papers authored by Wayne J. Thompson

Since Specialization

Citations

This map shows the geographic impact of Wayne J. Thompson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wayne J. Thompson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wayne J. Thompson more than expected).

Fields of papers citing papers by Wayne J. Thompson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wayne J. Thompson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wayne J. Thompson. The network helps show where Wayne J. Thompson may publish in the future.

Co-authors

The 25 scholars most cited alongside Wayne J. Thompson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Wayne J. Thompson Line = papers co-authored together Wayne J. Thompson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 48 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site Journal of Medicinal Chemistry ·M. Katharine Holloway, Jenny Wai, Thomas A. Halgren, Paula M.D. Fitzgerald, Joseph P. Vacca, Bruce D. Dorsey, Rhonda B. Levin, Wayne J. Thompson, L. Jenny Chen	1995	180
2	A general synthesis of 5-arylnicotinates The Journal of Organic Chemistry ·Wayne J. Thompson, John J. Gaudino	1984	176
3	Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl design Journal of Medicinal Chemistry ·Wayne J. Thompson, Paula M.D. Fitzgerald, M. Katharine Holloway, Emilio A. Emini, Paul L. Darke, Brian M. McKeever, William A. Schleif, J C Quintero, Joan A. Zugay	1992	136
4	N,N`-dissuccinimidyl carbonate: a useful reagent for alkoxycarbonylation of amines Tetrahedron Letters ·Arun K. Ghosh, Tien T. Doung, S. P. MCKEE, Wayne J. Thompson	1992	88
5	Nonpeptidal P₂ Ligands for HIV Protease Inhibitors: Structure-Based Design, Synthesis, and Biological Evaluation Journal of Medicinal Chemistry ·Arun K. Ghosh, John Kincaid, D. Eric Walters, Yan Chen, Narayan C. Chaudhuri, Wayne J. Thompson, Chris Culberson, Paula M.D. Fitzgerald, Hee Yoon Lee, S. P. MCKEE, Peter M. Munson, Tien T. Duong, Paul L. Darke, Joan A. Zugay, William A. Schleif, Melinda G. Axel, Juinn H. Lin, Joel R. Huff	1996	79
6	Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors Journal of Medicinal Chemistry ·Terry A. Lyle, Catherine M. Wiscount, James P. Guare, Wayne J. Thompson, Paul Anderson, Paul L. Darke, Joan A. Zugay, Emilio A. Emini, William A. Schleif	1991	74
7	3-Tetrahydrofuran and pyran urethanes as high-affinity P2-ligands for HIV-1 protease inhibitors Journal of Medicinal Chemistry ·Arun K. Ghosh, Wayne J. Thompson, S. P. MCKEE, Tien T. Duong, Terry A. Lyle, J. Chen, Paul L. Darke, Joan A. Zugay, Emilio A. Emini	1993	62
8	An efficient synthesis of hydroxyethylene dipeptide isosteres: the core unit of potent HIV-1 protease inhibitors The Journal of Organic Chemistry ·Arun K. Ghosh, S. P. MCKEE, Wayne J. Thompson	1991	57
9	Potent HIV protease inhibitors: the development of tetrahydrofuranylglycines as novel P2-ligands and pyrazine amides as P3-ligands Journal of Medicinal Chemistry ·Arun K. Ghosh, Wayne J. Thompson, M. K. HOLLOWAY, S. P. MCKEE, (unknown), (unknown), Peter M. Munson, Anthony M. Smith, Jenny Wai, P.L. Darke, (unknown), (unknown), (unknown), (unknown), (unknown)	1993	56
10	Synthesis and pharmacological evaluation of a series of dibenzo[a,d]cycloalkenimines as N-methyl-D-aspartate antagonists Journal of Medicinal Chemistry ·Wayne J. Thompson, Paul Anderson, Susan F. Britcher, Terry A. Lyle, J. Eric Thies, Catherine Magill, Sándor Varga, J. E. SCHWERING, Paulette A. Lyle	1990	56
11	An approach to the total synthesis of chlorothricolide: the synthesis of the top half The Journal of Organic Chemistry ·Robert E. Ireland, Wayne J. Thompson	1979	56
12	Structure-Based Design of HIV-1 Protease Inhibitors: Replacement of Two Amides and a 10.pi.-Aromatic System by a Fused Bis-tetrahydrofuran Journal of Medicinal Chemistry ·Arun K. Ghosh, Wayne J. Thompson, Paula M.D. Fitzgerald, J. Chris Culberson, Melinda G. Axel, S. P. MCKEE, Joel R. Huff, Paul Anderson	1994	54
13	An efficient synthesis of arylpyrazines and bipyridines The Journal of Organic Chemistry ·Wayne J. Thompson, James H. Jones, Paulette A. Lyle, J. Eric Thies	1988	54
14	The Development of Cyclic Sulfolanes as Novel and High-Affinity P2 Ligands for HIV-1 Protease Inhibitors Journal of Medicinal Chemistry ·Arun K. Ghosh, Hee Yoon Lee, Wayne J. Thompson, Chris Culberson, M. Katharine Holloway, S. P. MCKEE, Peter M. Munson, Tien T. Duong, Anthony M. Smith	1994	42
15	HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: An investigation into the role of the P1' side chain on structure-activity Journal of Medicinal Chemistry ·Steven D. Young, Linda S. Payne, Wayne J. Thompson, Neil Gaffin, Terry A. Lyle, Susan F. Britcher, Samuel Graham, Thomas Schultz, A. A. Deana	1992	37
16	Potent HIV-1 protease inhibitors: stereoselective synthesis of a dipeptide mimic The Journal of Organic Chemistry ·Arun K. Ghosh, S. P. MCKEE, Wayne J. Thompson, Paul L. Darke, Joan C Zugay	1993	36
17	A convenient method for the synthesis of α-Ketoesters from aldehydes Tetrahedron Letters ·David Horne, John J. Gaudino, Wayne J. Thompson	1984	35
18	Cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitors Journal of Medicinal Chemistry ·Arun K. Ghosh, Wayne J. Thompson, Hee Yoon Lee, S. P. MCKEE, Peter M. Munson, Tien T. Duong, Paul L. Darke, Joan A. Zugay, Emilio A. Emini	1993	34
19	Cyclic sulfone-3-carboxamides as novel P2-ligands for Ro 31-8959 based HIV-1 protease inhibitors Bioorganic & Medicinal Chemistry Letters ·Arun K. Ghosh, Wayne J. Thompson, Peter M. Munson, Wenming Liu, Joel R. Huff	1995	33
20	The total synthesis of (.+-.)-damsin Journal of the American Chemical Society ·Richard A. Kretchmer, Wayne J. Thompson	1976	33

About Wayne J. Thompson

Wayne J. Thompson is a scholar working on Organic Chemistry, Molecular Biology, Infectious Diseases, Virology and Pharmacology, having authored 48 papers that have together received 1.7k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (20 papers), Click Chemistry and Applications (13 papers), Chemical Synthesis and Analysis (12 papers), HIV Research and Treatment (8 papers), Carbohydrate Chemistry and Synthesis (7 papers), Asymmetric Synthesis and Catalysis (6 papers), Pneumocystis jirovecii pneumonia detection and treatment (3 papers) and Synthesis and Reactivity of Heterocycles (3 papers). The work is most often cited by research in Virology (315 citations), Organic Chemistry (1.1k citations), Infectious Diseases (523 citations), Molecular Biology (698 citations) and Computational Theory and Mathematics (150 citations). Wayne J. Thompson has collaborated with scholars based in United States and Japan. Frequent co-authors include Arun K. Ghosh, John J. Gaudino, S. P. MCKEE, Paul L. Darke, Paula M.D. Fitzgerald, Robert E. Ireland, M. Katharine Holloway, Joan A. Zugay, Emilio A. Emini and William A. Schleif. Their work appears in journals such as Journal of Medicinal Chemistry, The Journal of Organic Chemistry, Tetrahedron Letters, Journal of the American Chemical Society and Bioorganic & Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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