Tom C. Freeman

20.6k citations

150 papers · 8.9k · 2 hit papers · h-index 49

Impact in

Neurology top 0.5%
- Neuroinflammation and Neurodegeneration Mechanisms
Immunology top 1%
- Immune cells in cancer
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses

Papers in

Molecular Biology 74
- Bioinformatics and Genomic Networks 13
- Gene expression and cancer classification 8
- Epigenetics and DNA Methylation 6
Immunology 32
- T-cell and B-cell Immunology 9
- Immune cells in cancer 9
- Immune Cell Function and Interaction 7
- Immune Response and Inflammation 6

Co-authors: J. Kenneth Baillie (6 shared papers)David Hume (15 shared papers)Peter J. Richardson (6 shared papers)Barry W. McColl (3 shared papers)Kim Summers (5 shared papers)Kathleen Grabert (2 shared papers)Anton J. Enright (5 shared papers)Sara Clohisey (2 shared papers)
Journals: BMC Genomics (6 papers)Scientific Reports (5 papers)PLoS ONE (4 papers)European Journal of Immunology (4 papers)Journal of Crohn s and Colitis (4 papers)
Partner nations: United Kingdom United States Germany

In The Last Decade

Tom C. Freeman

146 papers receiving 8.8k citations

Tom C. Freeman's Hit Papers

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Microglial brain region−dependent diversity and selective regional sensitivities to aging 2016 · 887 citations

Peers

Countries citing papers authored by Tom C. Freeman

Since Specialization

Citations

This map shows the geographic impact of Tom C. Freeman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tom C. Freeman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tom C. Freeman more than expected).

Fields of papers citing papers by Tom C. Freeman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tom C. Freeman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tom C. Freeman. The network helps show where Tom C. Freeman may publish in the future.

Co-authors

The 25 scholars most cited alongside Tom C. Freeman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tom C. Freeman Line = papers co-authored together Tom C. Freeman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 150 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Microglial brain region−dependent diversity and selective regional sensitivities to aging Nature Neuroscience ·Kathleen Grabert, Tom Michoel, Michail H. Karavolos, Sara Clohisey, J. Kenneth Baillie, Mark P. Stevens, Tom C. Freeman, Kim Summers, Barry W. McColl Hit paper breakdown →	2016	887
2	Fulminant Jejuno-Ileitis following Ablation of Enteric Glia in Adult Transgenic Mice Cell ·Toby G. Bush, Tor Savidge, Tom C. Freeman, Hilary J. Cox, Elizabeth A. Campbell, Lennart Mucke, Martin H. Johnson, Michael V. Sofroniew	1998	483
3	Tissue distribution of adenosine receptor mRNAs in the rat British Journal of Pharmacology ·Alistair K. Dixon, Amelie K. Gubitz, D.J.S. Sirinathsinghji, Peter J. Richardson, Tom C. Freeman	1996	474
4	Network visualization and analysis of gene expression data using BioLayout Express3D Nature Protocols ·Athanasios Theocharidis, Stjin van Dongen, Anton J. Enright, Tom C. Freeman	2009	311
5	An expression atlas of human primary cells: inference of gene function from coexpression networks BMC Genomics ·Neil A. Mabbott, J. Kenneth Baillie, Helen Brown, Tom C. Freeman, David Hume	2013	299
6	The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9 European Journal of Immunology ·Marc‐André Wurbel, Jean‐Marc Philippe, Catherine Nguyen, Geneviève Victoréro, Tom C. Freeman, Peter Wooding, Arkadiusz Miążek, Marie‐Geneviève Mattéi, Marie Malissen, Bertrand Jordan, Bernard MALISSEN, Alice Carrier, Philippe Naquet	2000	291
7	Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression Breast Cancer Research ·Richard Clarkson, Matthew T. Wayland, Jennifer Lee, Tom C. Freeman, Christine J. Watson	2003	280
8	Bovine Host Genetic Variation Influences Rumen Microbial Methane Production with Best Selection Criterion for Low Methane Emitting and Efficiently Feed Converting Hosts Based on Metagenomic Gene Abundance PLoS Genetics ·R. Roehe, R.J. Dewhurst, Carol-Anne Duthie, John A. Rooke, Nest McKain, D.W. Ross, Jimmy J. Hyslop, A. Waterhouse, Tom C. Freeman, Mick Watson, R. J. Wallace Hit paper breakdown →	2016	251
9	Mapping macrophage polarization over the myocardial infarction time continuum Basic Research in Cardiology ·Alan J. Mouton, Kristine Y. DeLeon‐Pennell, O. J. Gonzalez, Elizabeth R. Flynn, Tom C. Freeman, Jeffrey J. Saucerman, Michael R. Garrett, Yonggang Ma, Romain Harmancey, Merry L. Lindsey	2018	249
10	Delta-like and Gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12 Current Biology ·Shuji Takada, Maxine Tevendale, J. Baker, Pantelis Georgiades, Elizabeth A. Campbell, Tom C. Freeman, Martin H. Johnson, Martina Paulsen, Anne C. Ferguson‐Smith	2000	197
11	Molecular Signatures Distinguish Human Central Memory from Effector Memory CD8 T Cell Subsets The Journal of Immunology ·Tim Willinger, Tom C. Freeman, Hitoshi Hasegawa, Andrew J. McMichael, Margaret Callan	2005	180
12	Construction, Visualisation, and Clustering of Transcription Networks from Microarray Expression Data PLoS Computational Biology ·Tom C. Freeman, Leon Goldovsky, Markus Brosch, Stijn van Dongen, Pierre Mazière, Russell Grocock, Shiri Freilich, Janet M. Thornton, Anton J. Enright	2007	178
13	The rumen microbiome as a reservoir of antimicrobial resistance and pathogenicity genes is directly affected by diet in beef cattle Microbiome ·Marc Auffret, R.J. Dewhurst, Carol-Anne Duthie, John A. Rooke, R. J. Wallace, Tom C. Freeman, Robert Stewart, Mick Watson, R. Roehe	2017	142
14	Human Naive CD8 T Cells Down-Regulate Expression of the WNT Pathway Transcription Factors Lymphoid Enhancer Binding Factor 1 and Transcription Factor 7 (T Cell Factor-1) following Antigen Encounter In Vitro and In Vivo The Journal of Immunology ·Tim Willinger, Tom C. Freeman, Mark Herbert, Hitoshi Hasegawa, Andrew J. McMichael, Margaret Callan	2006	140
15	Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors Cancer Immunology Research ·Ajit J. Nirmal, Tim Regan, Barbara Shih, David Hume, Andrew H. Sims, Tom C. Freeman	2018	137
16	Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis Basic Research in Cardiology ·Alan J. Mouton, Yonggang Ma, O. J. Gonzalez, Michael J. Daseke, Elizabeth R. Flynn, Tom C. Freeman, Michael R. Garrett, Kristine Y. DeLeon‐Pennell, Merry L. Lindsey	2019	131
17	A gene expression atlas of the domestic pig BMC Biology ·Tom C. Freeman, Alasdair Ivens, J. Kenneth Baillie, Dario Beraldi, Mark Barnett, David A. Dorward, Alison Downing, Lynsey Fairbairn, Ronan Kapétanovic, Sobia Raza, Andru Tomoiu, Ramiro Alberio, Chunlei Wu, Andrew I. Su, Kim Summers, Christopher K. Tuggle, Alan Archibald, David Hume	2012	127
18	Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis Development ·Diane Rebourcet, Peter J. O’Shaughnessy, Jean-Luc Pitetti, Ana Monteiro, Laura O’Hara, Laura Milne, Yi Ting Tsai, Lyndsey Cruickshanks, Dieter Riethmacher, Florian Guillou, Rod T. Mitchell, Rob vanʼt Hof, Tom C. Freeman, Serge Nef, Lee B. Smith	2014	113
19	Sertoli Cells Maintain Leydig Cell Number and Peritubular Myoid Cell Activity in the Adult Mouse Testis PLoS ONE ·Diane Rebourcet, Peter J. O’Shaughnessy, Ana Monteiro, Laura Milne, Lyndsey Cruickshanks, N. Weitzel Jeffrey, Florian Guillou, Tom C. Freeman, Rod T. Mitchell, Lee B. Smith	2014	112
20	The Genes Induced by Signal Transducer and Activators of Transcription (STAT)3 and STAT5 in Mammary Epithelial Cells Define the Roles of these STATs in Mammary Development Molecular Endocrinology ·Richard Clarkson, Marion P. Boland, Ekaterini A. Kritikou, Jennifer M. Lee, Tom C. Freeman, Paul G. Tiffen, Christine J. Watson	2005	106

About Tom C. Freeman

Tom C. Freeman is a scholar working on Molecular Biology, Immunology, Genetics, Oncology and Surgery, having authored 150 papers that have together received 8.9k indexed citations. Recurring topics across this work include Bioinformatics and Genomic Networks (13 papers), T-cell and B-cell Immunology (9 papers), Immune cells in cancer (9 papers), Gene expression and cancer classification (8 papers), Neuroinflammation and Neurodegeneration Mechanisms (8 papers), Immune Cell Function and Interaction (7 papers), Epigenetics and DNA Methylation (6 papers) and Immune Response and Inflammation (6 papers). The work is most often cited by research in Neurology (1.2k citations), Immunology (2.0k citations), Physiology (459 citations), Biological Psychiatry (163 citations) and Developmental Neuroscience (254 citations). Tom C. Freeman has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include J. Kenneth Baillie, David Hume, Peter J. Richardson, Barry W. McColl, Kim Summers, Kathleen Grabert, Anton J. Enright, Sara Clohisey, Mark P. Stevens and Tom Michoel. Their work appears in journals such as BMC Genomics, Scientific Reports, PLoS ONE, European Journal of Immunology and Journal of Crohn s and Colitis.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Tom C. Freeman

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All Works

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