Rupal A. Patel

459 citations

18 papers · 421 · h-index 13

Impact in

Hepatology top 5%
- Hepatitis C virus research
Computational Theory and Mathematics top 5%
- Computational Drug Discovery Methods

Papers in

Hepatology 14
- Hepatitis C virus research 14
Physical and Theoretical Chemistry 2
- thermodynamics and calorimetric analyses 2

Co-authors: Richard E. Showalter (7 shared papers)Laurie A. LeBrun (5 shared papers)Barbara Meurer‐Grimes (1 shared paper)Gian Sberna (1 shared paper)Bin Li (1 shared paper)Howard G. Wildman (1 shared paper)Natalie N. M. Nguyen (1 shared paper)Kevin R. Steffy (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (12 papers)Journal of Natural Products (2 papers)Antiviral Research (2 papers)Assay and Drug Development Technologies (2 papers)

In The Last Decade

Rupal A. Patel

18 papers receiving 330 citations

Peers

Countries citing papers authored by Rupal A. Patel

Since Specialization

Citations

This map shows the geographic impact of Rupal A. Patel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rupal A. Patel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rupal A. Patel more than expected).

Fields of papers citing papers by Rupal A. Patel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rupal A. Patel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rupal A. Patel. The network helps show where Rupal A. Patel may publish in the future.

Co-authors

The 25 scholars most cited alongside Rupal A. Patel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Rupal A. Patel Line = papers co-authored together Rupal A. Patel links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	A Diketopiperazine Dimer from a Marine-Derived Isolate of Aspergillus niger Journal of Natural Products ·Simon P. B. Ovenden, Gian Sberna, Howard G. Wildman, Rupal A. Patel, Bin Li, Kevin R. Steffy, Natalie N. M. Nguyen, Barbara Meurer‐Grimes +1 other	2004	50
2	Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase Bioorganic & Medicinal Chemistry Letters ·Frank Ruebsam, Douglas E. Murphy, Chinh V. Tran, Lian‐Sheng Li, Jingjing Zhao, Peter S. Dragovich, Alan X. Xiang, Zhongxiang Sun	2009	41
3	Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: Exploration of 7′-substitution of benzothiadiazine Bioorganic & Medicinal Chemistry Letters ·Yuefen Zhou, Stephen E. Webber, Douglas E. Murphy, Lian‐Sheng Li, Peter S. Dragovich, Chinh V. Tran, Zhongxiang Sun, Frank Ruebsam	2008	38
4	Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase Bioorganic & Medicinal Chemistry Letters ·Frank Ruebsam, Stephen E. Webber, Martin T. Tran, Chinh V. Tran, Douglas E. Murphy, Jingjing Zhao, Peter S. Dragovich, Sun Hee Kim	2008	36
5	Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7′-substituents and initial pharmacokinetic assessments Bioorganic & Medicinal Chemistry Letters ·Lian‐Sheng Li, Yuefen Zhou, Douglas E. Murphy, Nebojsa S. Stankovic, Jingjing Zhao, Peter S. Dragovich, Thomas M. Bertolini, Zhongxiang Sun	2008	31
6	Anti-HCV Bioactivity of Pseudoguaianolides from Parthenium hispitum Journal of Natural Products ·Jin‐Feng Hu, Rupal A. Patel, Bin Li, Eliane Garo, Grayson Hough, Matt G. Goering, Hye‐Dong Yoo, Mark O’Neil-Johnson	2007	29
7	Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 2: Variation of the 2- and 6-pyridazinone substituents Bioorganic & Medicinal Chemistry Letters ·Yuefen Zhou, Lian‐Sheng Li, Peter S. Dragovich, Douglas E. Murphy, Chinh V. Tran, Frank Ruebsam, Stephen E. Webber, Amit M. Shah	2008	28
8	Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase Bioorganic & Medicinal Chemistry Letters ·Sun Hee Kim, Martin T. Tran, Frank Ruebsam, Alan X. Xiang, Benjamin K. Ayida, Julie K. Blazel, Chinh V. Tran, Douglas E. Murphy	2008	28
9	5,6-Dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase Bioorganic & Medicinal Chemistry Letters ·Frank Ruebsam, Chinh V. Tran, Lian‐Sheng Li, Sun Hee Kim, Alan X. Xiang, Yuefen Zhou, Julie K. Blazel, Zhongxiang Sun	2008	25
10	4-(1,1-Dioxo-1,4-dihydro-1λ6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase Bioorganic & Medicinal Chemistry Letters ·Julie K. Blazel, Stephen E. Webber, Chinh V. Tran, Peter S. Dragovich, Zhongxiang Sun, Frank Ruebsam, Alan X. Xiang, Jingjing Zhao	2008	23
11	Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents Bioorganic & Medicinal Chemistry Letters ·Peter S. Dragovich, Julie K. Blazel, David A. Ellis, Qing Han, Ruhi Kamran, Charles R. Kissinger, Laurie A. LeBrun, Lian‐Sheng Li	2008	22
12	Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties Bioorganic & Medicinal Chemistry Letters ·Maria V. Sergeeva, Yuefen Zhou, Darian M. Bartkowski, Thomas G. Nolan, Daniel A. Norris, Ellen Okamoto, Leo Kirkovsky, Ruhi Kamran	2008	20
13	Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase Bioorganic & Medicinal Chemistry Letters ·Frank Ruebsam, Zhongxiang Sun, Benjamin K. Ayida, Stephen E. Webber, Yuefen Zhou, Qiang Zhao, Charles R. Kissinger, Richard E. Showalter	2008	15
14	Identification of Ligand Binding by Protein Stabilization: Comparison of ATLAS with Biophysical and Enzymatic Methods Assay and Drug Development Technologies ·Peggy A. Thompson, Shaohui Wang, Lindsay J. Howett, Meimei Wang, Rupal A. Patel, April M. Averill, Richard E. Showalter, Bin Li	2008	11
15	5,5′- and 6,6′-Dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase Bioorganic & Medicinal Chemistry Letters ·Julie K. Blazel, Chinh V. Tran, Frank Ruebsam, Douglas E. Murphy, Lian‐Sheng Li, Jingjing Zhao, Yuefen Zhou, Alan X. Xiang	2009	11
16	ATLAS—A High-Throughput Affinity-Based Screening Technology for Soluble Proteins: Technology Application Using p38 MAP Kinase Assay and Drug Development Technologies ·Rupal A. Patel, Laurie A. LeBrun, Shaohui Wang, Lindsay J. Howett, Peggy A. Thompson, James Richard Appleman, Bin Li	2008	8
17	In Vitro Combination Studies of ANA598 with Anti-HCV Agents Demonstrate Enhanced Anti-viral Activity Antiviral Research ·Rupal A. Patel, Peggy A. Thompson, Richard E. Showalter, James Richard Appleman	2010	4
18	In Vitro Combination of ANA598 with Other Anti-HCV Agents can Eliminate the Emergence of Resistant Colonies Antiviral Research ·Peggy A. Thompson, Richard E. Showalter, Rupal A. Patel, James Richard Appleman	2010	1

About Rupal A. Patel

Rupal A. Patel is a scholar working on Hepatology, Physical and Theoretical Chemistry, Molecular Biology, Cancer Research and Pharmacology, having authored 18 papers that have together received 421 indexed citations. Recurring topics across this work include Hepatitis C virus research (14 papers), thermodynamics and calorimetric analyses (2 papers), Phenothiazines and Benzothiazines Synthesis and Activities (2 papers), Protein Structure and Dynamics (2 papers), Protein Interaction Studies and Fluorescence Analysis (2 papers), Microbial Natural Products and Biosynthesis (1 paper) and Sesquiterpenes and Asteraceae Studies (1 paper). The work is most often cited by research in Hepatology (147 citations), Computational Theory and Mathematics (94 citations), Organic Chemistry (93 citations), Pharmacology (30 citations) and Biotechnology (10 citations). Frequent co-authors include Richard E. Showalter, Laurie A. LeBrun, Barbara Meurer‐Grimes, Gian Sberna, Bin Li, Howard G. Wildman, Natalie N. M. Nguyen, Kevin R. Steffy, Chinh V. Tran and Stephen E. Webber. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Natural Products, Antiviral Research and Assay and Drug Development Technologies.

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