Paul E. Erdman

752 citations

18 papers · 617 · h-index 12

Impact in

Organic Chemistry top 10%
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
Computational Theory and Mathematics top 5%
- Computational Drug Discovery Methods

Papers in

Organic Chemistry 11
- Synthesis and biological activity 10
- Synthesis and Characterization of Heterocyclic Compounds 6
Computational Theory and Mathematics 5
- Computational Drug Discovery Methods 5

Co-authors: Moorthy S. S. Palanki (6 shared papers)Lynn J. Ransone (5 shared papers)Mark J. Suto (4 shared papers)Mark E. Goldman (3 shared papers)Philip B. Cox (2 shared papers)Anthony M. Manning (3 shared papers)Leah M. Gayo (2 shared papers)Brydon L. Bennett (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Journal of Medicinal Chemistry (5 papers)ACS Chemical Biology (1 paper)ACS Medicinal Chemistry Letters (1 paper)Journal of Molecular Medicine (1 paper)
Partner nations: United States Japan Israel

In The Last Decade

Paul E. Erdman

18 papers receiving 566 citations

Peers

Countries citing papers authored by Paul E. Erdman

Since Specialization

Citations

This map shows the geographic impact of Paul E. Erdman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul E. Erdman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul E. Erdman more than expected).

Fields of papers citing papers by Paul E. Erdman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul E. Erdman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul E. Erdman. The network helps show where Paul E. Erdman may publish in the future.

Co-authors

The 25 scholars most cited alongside Paul E. Erdman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paul E. Erdman Line = papers co-authored together Paul E. Erdman links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models Cell ·Waleed Minzel, Avanthika Venkatachalam, Avner Fink, Eric Hung, Guy Brachya, Ido Burstain, Maya Shaham, Amitai Rivlin	2018	131
2	Inhibitors of NF-κB and AP-1 Gene Expression: SAR Studies on the Pyrimidine Portion of 2-Chloro-4-trifluoromethylpyrimidine-5-[N-(3‘,5‘-bis(trifluoromethyl)phenyl)carboxamide] Journal of Medicinal Chemistry ·Moorthy S. S. Palanki, Paul E. Erdman, Leah M. Gayo, Graziella I. Shevlin, Mark E. Goldman, Lynn J. Ransone, Brydon L. Bennett, Anthony M. Manning	2000	77
3	Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches ACS Chemical Biology ·Igor Mochalkin, J. Richard Miller, Lakshmi S. Narasimhan, Venkataraman Thanabal, Paul E. Erdman, Philip B. Cox, J. V. N. Vara Prasad, Sandra Lightle	2009	77
4	The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen Journal of Medicinal Chemistry ·Jennifer R. Riggs, Mark A. Nagy, Jan Elsner, Paul E. Erdman, Dan Cashion, Dale Robinson, Roy Harris, Dehua Huang	2017	50
5	Structure–Activity Relationship Studies of Ethyl 2-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: An Inhibitor of AP-1 and NF-κB Mediated Gene Expression Bioorganic & Medicinal Chemistry Letters ·Moorthy S. S. Palanki, Leah M. Gayo, Graziella I. Shevlin, Paul E. Erdman, Mark Sato, Mark E. Goldman, Lynn J. Ransone, Cheryl Spooner	2002	41
6	2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3‘,5‘-bis(trifluoromethyl)phenyl)- carboxamide: A Potent Inhibitor of NF-κB- and AP-1-Mediated Gene Expression Identified Using Solution-Phase Combinatorial Chemistry Journal of Medicinal Chemistry ·Colin G. Bigam, Paul E. Erdman, Moorthy S. S. Palanki, David Walter Anderson, Mark E. Goldman, Lynn J. Ransone, Mark J. Suto +1 other	1998	38
7	The design and synthesis of novel orally active inhibitors of AP-1 and NF-κB mediated transcriptional activation. SAR of In vitro and In vivo studies Bioorganic & Medicinal Chemistry Letters ·Moorthy S. S. Palanki, Paul E. Erdman, Minghuan Ren, Mark J. Suto, Brydon L. Bennett, Anthony M. Manning, Lynn J. Ransone, Cheryl Spooner	2003	35
8	Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001 Journal of Medicinal Chemistry ·Mark A. Nagy, Robert Hilgraf, Deborah S. Mortensen, Jan Elsner, Jayashree G. Tikhe, Won Hyung Yoon, David Paisner, Mercedes Delgado	2021	35
9	Design and Synthesis of Pyrrolidine-based Fragments That Sample Three-dimensional Molecular Space ACS Medicinal Chemistry Letters ·Philip Garner, Philip B. Cox, Upendra A. Rathnayake, Nicholas Holloran, Paul E. Erdman	2019	31
10	Novel inhibitors of AP-1 and NF-κB mediated gene expression: structure–activity relationship studies of ethyl 4-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carboxylate Bioorganic & Medicinal Chemistry Letters ·Moorthy S. S. Palanki, Paul E. Erdman, Anthony M. Manning, Arnold Ow, Lynn J. Ransone, Cheryl Spooner, Carla M. Suto, Mark J. Suto	2000	27
11	Inhibition of Nuclear Factor-κB in T Cells Suppresses Lung Fibrosis American Journal of Respiratory and Critical Care Medicine ·Hajime Fujimoto, Corina N. D’Alessandro‐Gabazza, Moorthy S. S. Palanki, Paul E. Erdman, Takehiro Takagi, Esteban Cesar Gabazza, Nelson E. Bruno, Yutaka Yano	2007	23
12	Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors Bioorganic & Medicinal Chemistry Letters ·Garrick K. Packard, Patrick Papa, Jennifer R. Riggs, Paul E. Erdman, Lida R. Tehrani, Dale Robinson, Roy Harris, Graziella I. Shevlin	2011	18
13	The novel protein homeostatic modulator BTX306 is active in myeloma and overcomes bortezomib and lenalidomide resistance Journal of Molecular Medicine ·Jianxuan Zou, Richard Julian Jones, Hua Wang, Isere Kuiatse, Fazal Shirazi, Elisabet Esteve Manasanch, Hans Chulhee Lee, Robert Sullivan	2020	11
14	Discovery of N-substituted 7-azaindoles as Pan-PIM kinases inhibitors – Lead optimization – Part III Bioorganic & Medicinal Chemistry Letters ·James Pribish, Elina Tserlin, Alexandre Gross, Mark Czekaj, Matthieu Barragué, Paul E. Erdman, Sachin Maniar, Luke Fire	2018	8
15	Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model Bioorganic & Medicinal Chemistry Letters ·Paul E. Erdman, Mark Czekaj, Luke Fire, James Pribish, Elina Tserlin, Sachin Maniar, Joseph D. Batchelor, Jin Yu Liu	2020	7
16	Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors – Lead series identification – Part II Bioorganic & Medicinal Chemistry Letters ·Neil D. Moorcroft, James Pribish, Elina Tserlin, Alexandre Gross, Mark Czekaj, Matthieu Barragué, Paul E. Erdman, Tahir N. Majid	2017	5
17	Discovery of a PDE4B and PDE4D selective bifunctional degrader for management of chronic inflammatory disorders Journal of Translational Autoimmunity ·Arvind Shakya, Qiao Liu, Chon Lai, Steven Greene, Paul E. Erdman, Athri D. Rathnayake, Angela Schoolmeesters, Connor M. Blair	2025	2
18	Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators Journal of Medicinal Chemistry ·Zhiguo Bian, Noel S. Wilson, David B. Duignan, Eric C. Breinlinger, Amanda W. Dombrowski, Paul E. Erdman, C. Michael Foley, Michael Friedman	2025	1

About Paul E. Erdman

Paul E. Erdman is a scholar working on Organic Chemistry, Computational Theory and Mathematics, Cancer Research, Molecular Biology and Hematology, having authored 18 papers that have together received 617 indexed citations. Recurring topics across this work include Synthesis and biological activity (10 papers), Synthesis and Characterization of Heterocyclic Compounds (6 papers), Computational Drug Discovery Methods (5 papers), Protein Degradation and Inhibitors (3 papers), NF-κB Signaling Pathways (3 papers), PI3K/AKT/mTOR signaling in cancer (3 papers), Acute Myeloid Leukemia Research (1 paper) and Phosphodiesterase function and regulation (1 paper). The work is most often cited by research in Organic Chemistry (203 citations), Computational Theory and Mathematics (101 citations), Cancer Research (69 citations), Pharmaceutical Science (24 citations) and Molecular Biology (189 citations). Paul E. Erdman has collaborated with scholars based in United States, Japan and Israel. Frequent co-authors include Moorthy S. S. Palanki, Lynn J. Ransone, Mark J. Suto, Mark E. Goldman, Philip B. Cox, Anthony M. Manning, Leah M. Gayo, Brydon L. Bennett, Sandra Lightle and Michael D. Huband. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, ACS Chemical Biology, ACS Medicinal Chemistry Letters and Journal of Molecular Medicine.

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Paul E. Erdman

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