Patrick R. Gentry

2.0k citations

32 papers · 1.6k · h-index 20

Impact in

Cellular and Molecular Neuroscience top 2%
- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology
- Neurotransmitter Receptor Influence on Behavior
Molecular Biology top 5%
- Receptor Mechanisms and Signaling
- Nicotinic Acetylcholine Receptors Study
- Pharmacological Receptor Mechanisms and Effects
- Chemical Synthesis and Analysis

Papers in

Molecular Biology 30
- Receptor Mechanisms and Signaling 27
- Pharmacological Receptor Mechanisms and Effects 5
- Nicotinic Acetylcholine Receptors Study 5
- Chemical Synthesis and Analysis 4
- Ion channel regulation and function 3
Cellular and Molecular Neuroscience 20
- Neuroscience and Neuropharmacology Research 15
- Neuropeptides and Animal Physiology 9

Co-authors: Craig W. Lindsley (27 shared papers)P. Jeffrey Conn (21 shared papers)Thomas M. Bridges (18 shared papers)Arthur Christopoulos (6 shared papers)Patrick M. Sexton (5 shared papers)Thomas P. Mathews (1 shared paper)Cody J. Wenthur (1 shared paper)Corey R. Hopkins (5 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (10 papers)Journal of Medicinal Chemistry (4 papers)ChemMedChem (2 papers)ACS Chemical Neuroscience (2 papers)The Annual Review of Pharmacology and Toxicology (1 paper)
Partner nations: United States Australia Denmark

In The Last Decade

Patrick R. Gentry

32 papers receiving 1.6k citations

Peers

Countries citing papers authored by Patrick R. Gentry

Since Specialization

Citations

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Fields of papers citing papers by Patrick R. Gentry

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick R. Gentry. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick R. Gentry. The network helps show where Patrick R. Gentry may publish in the future.

Co-authors

The 25 scholars most cited alongside Patrick R. Gentry, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Patrick R. Gentry Line = papers co-authored together Patrick R. Gentry links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 32 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	In Vivo Structure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors ACS Chemical Biology ·Jijun Hao, Joshua N. Ho, Jana A. Lewis, Kaleh Karim, R. Nathan Daniels, Patrick R. Gentry, Corey R. Hopkins, Craig W. Lindsley, Charles C. Hong	2009	316
2	Drugs for Allosteric Sites on Receptors The Annual Review of Pharmacology and Toxicology ·Cody J. Wenthur, Patrick R. Gentry, Thomas P. Mathews, Craig W. Lindsley	2011	220
3	Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats Journal of Pharmacology and Experimental Therapeutics ·Ashley E. Brady, Carrie K. Jones, Thomas M. Bridges, J. Phillip Kennedy, Analisa D. Thompson, J.U. Heiman, Micah L. Breininger, Patrick R. Gentry, Huiyong Yin, Satyawan Jadhav, Jana K. Shirey, P. Jeffrey Conn, Craig W. Lindsley	2008	167
4	Novel Allosteric Modulators of G Protein-coupled Receptors Journal of Biological Chemistry ·Patrick R. Gentry, Patrick M. Sexton, Arthur Christopoulos	2015	162
5	Discovery of the First Highly M5-Preferring Muscarinic Acetylcholine Receptor Ligand, an M5 Positive Allosteric Modulator Derived from a Series of 5-Trifluoromethoxy N -Benzyl Isatins Journal of Medicinal Chemistry ·Thomas M. Bridges, Joy E. Marlo, Colleen M. Niswender, Carrie K. Jones, Satyawan Jadhav, Patrick R. Gentry, Hyekyung C. Plumley, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley	2009	88
6	M₅Receptor Activation Produces Opposing Physiological Outcomes in Dopamine Neurons Depending on the Receptor's Location Journal of Neuroscience ·Daniel J. Foster, Patrick R. Gentry, José E. Lizardi-Ortiz, Thomas M. Bridges, Michael R. Wood, Colleen M. Niswender, David Sulzer, Craig W. Lindsley, Zixiu Xiang, P. Jeffrey Conn	2014	62
7	Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M5 PAM Bioorganic & Medicinal Chemistry Letters ·Thomas M. Bridges, J. Phillip Kennedy, Hyekyung P. Cho, Micah L. Breininger, Patrick R. Gentry, Corey R. Hopkins, P. Jeffrey Conn, Craig W. Lindsley	2009	60
8	Discovery of the First M₅-Selective and CNS Penetrant Negative Allosteric Modulator (NAM) of a Muscarinic Acetylcholine Receptor: (S)-9b-(4-Chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-one (ML375) Journal of Medicinal Chemistry ·Patrick R. Gentry, Masaya Kokubo, Thomas M. Bridges, Nathan R. Kett, Joel M. Harp, Hyekyung P. Cho, Emery Smith, Peter Chase, Peter Hodder, Colleen M. Niswender, J. Scott Daniels, P. Jeffrey Conn, Michael R. Wood, Craig W. Lindsley	2013	59
9	Crystal structure of the M ₅ muscarinic acetylcholine receptor Proceedings of the National Academy of Sciences ·Ziva Vuckovic, Patrick R. Gentry, Alice E. Berizzi, Kunio Hirata, Swapna Varghese, Geoff Thompson, Emma T. van der Westhuizen, Wessel A. C. Burger, Raphaël Rahmani, Céline Valant, Christopher J. Langmead, Craig W. Lindsley, Jonathan B. Baell, Andrew B. Tobin, Patrick M. Sexton, Arthur Christopoulos, David M. Thal	2019	56
10	Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: Development of a potent and highly selective M1 PAM Bioorganic & Medicinal Chemistry Letters ·Thomas M. Bridges, J. Phillip Kennedy, Meredith J. Noetzel, Micah L. Breininger, Patrick R. Gentry, P. Jeffrey Conn, Craig W. Lindsley	2010	46
11	Discovery of (S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): A Novel, CNS Penetrant Glucagon-Like Peptide 1 Receptor (GLP-1R) Positive Allosteric Modulator (PAM) Journal of Medicinal Chemistry ·Lindsey C. Morris, Kellie D. Nance, Patrick R. Gentry, Emily Days, C. David Weaver, Colleen M. Niswender, Analisa D. Thompson, Carrie K. Jones, Chuck W. Locuson, Ryan D. Morrison, J. Scott Daniels, Kevin D. Niswender, Craig W. Lindsley	2014	37
12	Synthesis and Structure–Activity Relationships of Allosteric Potentiators of the M₄ Muscarinic Acetylcholine Receptor ChemMedChem ·J. Phillip Kennedy, Thomas M. Bridges, Patrick R. Gentry, John T. Brogan, Alexander S. Kane, Carrie K. Jones, Ashley E. Brady, Jana K. Shirey, P. Jeffrey Conn, Craig W. Lindsley	2009	34
13	Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4) Bioorganic & Medicinal Chemistry Letters ·Richard D. Williams, Kari A. Johnson, Patrick R. Gentry, Colleen M. Niswender, (unknown), P. Jeffrey Conn, Craig W. Lindsley, Corey R. Hopkins	2009	31
14	Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties Bioorganic & Medicinal Chemistry Letters ·Thomas M. Bridges, Ashley E. Brady, J. Phillip Kennedy, R. Nathan Daniels, Nicole Miller, Kwango Kim, Micah L. Breininger, Patrick R. Gentry, John T. Brogan, Carrie K. Jones, P. Jeffrey Conn, Craig W. Lindsley	2008	30
15	Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: The continued optimization of an MLPCN probe molecule Bioorganic & Medicinal Chemistry Letters ·Michael S. Poslusney, Bruce J. Melancon, Patrick R. Gentry, Douglas J. Sheffler, Thomas M. Bridges, Thomas J. Utley, J. Scott Daniels, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Michael R. Wood	2013	27
16	Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric Modulators Molecular Pharmacology ·Alice E. Berizzi, Patrick R. Gentry, Patricia Rueda, Sandra den Hoedt, Patrick M. Sexton, Christopher J. Langmead, Arthur Christopoulos	2016	26
17	Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS) Bioorganic & Medicinal Chemistry Letters ·Darren W. Engers, Patrick R. Gentry, Richard D. Williams, Julie D. Bolinger, C. David Weaver, Usha N. Menon, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins	2010	26
18	Discovery, Synthesis and Characterization of a Highly Muscarinic Acetylcholine Receptor (mAChR)‐Selective M₅‐Orthosteric Antagonist, VU0488130 (ML381): A Novel Molecular Probe ChemMedChem ·Patrick R. Gentry, Masaya Kokubo, Thomas M. Bridges, Hyekyung P. Cho, Emery Smith, Peter Chase, Peter Hodder, Thomas J. Utley, Anuruddha Rajapakse, Frank W. Byers, Colleen M. Niswender, Ryan D. Morrison, J. Scott Daniels, Michael R. Wood, P. Jeffrey Conn, Craig W. Lindsley	2014	23
19	Development of a Highly Potent, Novel M₅Positive Allosteric Modulator (PAM) Demonstrating CNS Exposure: 1-((1H-Indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380) Journal of Medicinal Chemistry ·Patrick R. Gentry, Masaya Kokubo, Thomas M. Bridges, Meredith J. Noetzel, Hyekyung P. Cho, Atin Lamsal, Emery Smith, Peter Chase, Peter Hodder, Colleen M. Niswender, J. Scott Daniels, P. Jeffrey Conn, Craig W. Lindsley, Michael R. Wood	2014	22
20	Discovery of ML326: The first sub-micromolar, selective M5 PAM Bioorganic & Medicinal Chemistry Letters ·Patrick R. Gentry, Thomas M. Bridges, Atin Lamsal, Paige N. Vinson, Emery Smith, Peter Chase, Peter Hodder, Julie L. Engers, Colleen M. Niswender, J. Scott Daniels, P. Jeffrey Conn, Michael R. Wood, Craig W. Lindsley	2013	21

About Patrick R. Gentry

Patrick R. Gentry is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Spectroscopy, Endocrinology, Diabetes and Metabolism and Electronic, Optical and Magnetic Materials, having authored 32 papers that have together received 1.6k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (27 papers), Neuroscience and Neuropharmacology Research (15 papers), Neuropeptides and Animal Physiology (9 papers), Pharmacological Receptor Mechanisms and Effects (5 papers), Nicotinic Acetylcholine Receptors Study (5 papers), Mass Spectrometry Techniques and Applications (5 papers), Chemical Synthesis and Analysis (4 papers) and Ion channel regulation and function (3 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (743 citations), Molecular Biology (1.3k citations), Computational Theory and Mathematics (159 citations), Physiology (29 citations) and Biological Psychiatry (14 citations). Patrick R. Gentry has collaborated with scholars based in United States, Australia and Denmark. Frequent co-authors include Craig W. Lindsley, P. Jeffrey Conn, Thomas M. Bridges, Arthur Christopoulos, Patrick M. Sexton, Thomas P. Mathews, Cody J. Wenthur, Corey R. Hopkins, Colleen M. Niswender and R. Nathan Daniels. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, ChemMedChem, ACS Chemical Neuroscience and The Annual Review of Pharmacology and Toxicology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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