Patrick D. Hsu

54.1k citations
52 papers · 42.6k · 14 hit papers · h-index 33

Impact in

    • CRISPR and Genetic Engineering
    • Pluripotent Stem Cells Research
    • Genomics and Chromatin Dynamics
    • RNA Interference and Gene Delivery
    • Microbial Metabolic Engineering and Bioproduction
    • Epigenetics and DNA Methylation
  • Genetics top 0.5%
    • Virus-based gene therapy research
    • Animal Genetics and Reproduction

Papers in

    • CRISPR and Genetic Engineering 33
    • Gene Regulatory Network Analysis 5
    • Machine Learning in Bioinformatics 4
    • Protein Structure and Dynamics 3
    • Single-cell and spatial transcriptomics 2
    • SARS-CoV-2 detection and testing 3
    • SARS-CoV-2 and COVID-19 Research 3

Patrick D. Hsu

51 papers receiving 41.7k citations

Patrick D. Hsu's Hit Papers

Simulating 500 million years of evolution with a language model 2025 · 376 citations
3760+4+8Years since publication4k8k12k

Peers

Patrick D. Hsu
Comparison fields: 5 of 176
  • Molecular Biology 31.1k
  • Genetics 3.1k
  • Cell Biology 1.4k
  • Cancer Research 1.2k
  • Developmental Neuroscience 200
Replace F. Ann Ran with:
F. Ann Ran United States
David A. Scott United States
Anne‐Claude Gingras Canada
DAVID EDWIN HILL United States
J. Keith Joung United States
Timothy R. Hughes Canada
Peter D’Eustachio United States
Neville E. Sanjana United States
Ophir Shalem United States
Juri Rappsilber United Kingdom
Patrick D. Hsu relative to F. Ann Ran United States F. Ann Ran's profile →
Citations per field
00.5×1.5×2.0×
F. Ann Ran · 1×
Citations per year

Countries citing papers authored by Patrick D. Hsu

Since Specialization
Citations

This map shows the geographic impact of Patrick D. Hsu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick D. Hsu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick D. Hsu more than expected).

Fields of papers citing papers by Patrick D. Hsu

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick D. Hsu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick D. Hsu. The network helps show where Patrick D. Hsu may publish in the future.

Co-authors

The 25 scholars most cited alongside Patrick D. Hsu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Patrick D. Hsu Line = papers co-authored together Patrick D. Hsu links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 52 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Multiplex Genome Engineering Using CRISPR/Cas Systems
Hit paper breakdown →
201312484
2
Genome engineering using the CRISPR-Cas9 system
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20138883
3
Development and Applications of CRISPR-Cas9 for Genome Engineering
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20144611
4
DNA targeting specificity of RNA-guided Cas9 nucleases
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20133823
5
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
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20132804
6
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
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20142265
7
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
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20141917
8
Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
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2018934
9
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
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2014782
10
Optical control of mammalian endogenous transcription and epigenetic states
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2013683
11 2020377
12
Simulating 500 million years of evolution with a language model
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2025376
13 2016299
14
Sequence modeling and design from molecular to genome scale with Evo
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2024277
15 2016259
16 2021219
17 2018214
18
How to build the virtual cell with artificial intelligence: Priorities and opportunities
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2024171
19 2015160
20 2022147

About Patrick D. Hsu

Patrick D. Hsu is a scholar working on Molecular Biology, Infectious Diseases, Cellular and Molecular Neuroscience, Health Informatics and Oncology, having authored 52 papers that have together received 42.6k indexed citations. Recurring topics across this work include CRISPR and Genetic Engineering (33 papers), Gene Regulatory Network Analysis (5 papers), Machine Learning in Bioinformatics (4 papers), Photoreceptor and optogenetics research (3 papers), SARS-CoV-2 detection and testing (3 papers), Protein Structure and Dynamics (3 papers), SARS-CoV-2 and COVID-19 Research (3 papers) and Single-cell and spatial transcriptomics (2 papers). The work is most often cited by research in Molecular Biology (31.1k citations), Genetics (3.1k citations), Cell Biology (1.4k citations), Cancer Research (1.2k citations) and Developmental Neuroscience (200 citations). Patrick D. Hsu has collaborated with scholars based in United States, Japan and China. Frequent co-authors include Feng Zhang, F. Ann Ran, David A. Scott, Vineeta Agarwala, Eric S. Lander, Xuebing Wu, Jason B. Wright, Luciano A. Marraffini, Naomi Habib and Silvana Konermann. Their work appears in journals such as Cell, Nature, Nature Biotechnology, Science and Cell Systems.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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