P. Vreken

7.3k citations

81 papers · 4.6k · h-index 35

Impact in

Clinical Biochemistry top 0.2%
- Metabolism and Genetic Disorders
Biochemistry top 1%

Papers in

Molecular Biology 69
- Biochemical and Molecular Research 25
- Peroxisome Proliferator-Activated Receptors 23
- Mitochondrial Function and Pathology 9
- RNA modifications and cancer 8
- Cancer therapeutics and mechanisms 6
Clinical Biochemistry 38
- Metabolism and Genetic Disorders 38

Co-authors: Ronald J. A. Wanders (31 shared papers)André B. P. Kuilenburg (27 shared papers)Hans R. Waterham (12 shared papers)A. H. van Gennip (13 shared papers)Albert H. Gennip (22 shared papers)P. G. Barth (9 shared papers)Sacha Ferdinandusse (8 shared papers)Ronney A. De Abreu (11 shared papers)
Journals: Journal of Inherited Metabolic Disease (24 papers)Advances in experimental medicine and biology (6 papers)Biochemical Society Transactions (6 papers)Journal of Lipid Research (3 papers)The Journal of Pediatrics (3 papers)
Partner nations: Netherlands United Kingdom United States

In The Last Decade

P. Vreken

81 papers receiving 4.5k citations

Peers

Countries citing papers authored by P. Vreken

Since Specialization

Citations

This map shows the geographic impact of P. Vreken's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by P. Vreken with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites P. Vreken more than expected).

Fields of papers citing papers by P. Vreken

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by P. Vreken. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by P. Vreken. The network helps show where P. Vreken may publish in the future.

Co-authors

The 25 scholars most cited alongside P. Vreken, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with P. Vreken Line = papers co-authored together P. Vreken links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 81 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Defective Remodeling of Cardiolipin and Phosphatidylglycerol in Barth Syndrome Biochemical and Biophysical Research Communications ·P. Vreken, Fredoen Valianpour, Leo Nijtmans, Les Grivell, Barbara Plecko, Ronald J.A. Wanders, P. G. Barth	2000	322
2	Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene. PubMed ·André B. P. Kuilenburg, Janet Haasjes, Dick J. Richel, Lida Zoetekouw, Henk van Lenthe, Ronney A. De Abreu, Jan Gerard Maring, P. Vreken, A. H. van Gennip	2000	311
3	Mutations in the 3β-Hydroxysterol Δ24-Reductase Gene Cause Desmosterolosis, an Autosomal Recessive Disorder of Cholesterol Biosynthesis The American Journal of Human Genetics ·Hans R. Waterham, Janet Koster, G. J. Romeijn, Raoul C. M. Hennekam, P. Vreken, Hans C. Andersson, David Fitzpatrick, Richard I. Kelley, Ronald J. A. Wanders	2001	282
4	Smith-Lemli-Opitz Syndrome Is Caused by Mutations in the 7-Dehydrocholesterol Reductase Gene The American Journal of Human Genetics ·Hans R. Waterham, Frits A. Wijburg, Raoul C. M. Hennekam, P. Vreken, Bwee Tien Poll‐The, L. Dorland, Marinus Durán, Petr Jira, Jan Smeıtınk, Ron A. Wevers, Ronald J. A. Wanders	1998	225
5	Disorders of mitochondrial fatty acyl‐CoA β‐oxidation Journal of Inherited Metabolic Disease ·Ronald J. A. Wanders, P. Vreken, M. E. J. den Boer, Frits A. Wijburg, A. H. van Gennip, Lodewijk IJlst	1999	211
6	Peroxisomal fatty acid α- and β-oxidation in humans: enzymology, peroxisomal metabolite transporters and peroxisomal diseases Biochemical Society Transactions ·Ronald J. A. Wanders, P. Vreken, Sacha Ferdinandusse, Gerbert A. Jansen, Hans R. Waterham, Carlo W.T. van Roermund, E.G. van Grunsven	2001	199
7	Peroxisomal fatty acid α- and β-oxidation in humans: enzymology, peroxisomal metabolite transporters and peroxisomal diseases Biochemical Society Transactions ·Ronald J. A. Wanders, P. Vreken, Sacha Ferdinandusse, Gerbert A. Jansen, Hans R. Waterham, Carlo W.T. van Roermund, E.G. van Grunsven	2001	186
8	Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy Nature Genetics ·Sacha Ferdinandusse, (unknown), Peter T. Clayton, (unknown), (unknown), John T. Allen, Brendan McLean, (unknown), P. Vreken, Hans R. Waterham, Ronald J. A. Wanders	2000	173
9	Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy Biochemical Society Transactions ·Sacha Ferdinandusse, Simone Denis, Peter T. Clayton, Anne Graham, J E Rees, John T. Allen, Brendan McLean, Andrew Brown, P. Vreken, Hans R. Waterham, Ronald J. A. Wanders	2001	152
10	Significantly reduced docosahexaenoic and docosapentaenoic acid concentrations in erythrocyte membranes from schizophrenic patients compared with a carefully matched control group Biological Psychiatry ·Johanna Assies, Ritsaert Lieverse, P. Vreken, R. J. A. Wanders, Peter M.J.A Dingemans, Donald H. Linszen	2001	149
11	X‐linked cardioskeletal myopathy and neutropenia (Barth syndrome) (MIM 302060) Journal of Inherited Metabolic Disease ·P. G. Barth, Ronald J. A. Wanders, P. Vreken, Emiel A. M. Janssen, John C. Lam, Frank Baas	1999	136
12	Peroxisomal d -hydroxyacyl-CoA dehydrogenase deficiency: Resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency Proceedings of the National Academy of Sciences ·E.G. van Grunsven, E. van Berkel, Lodewijk IJlst, P. Vreken, Johannis B.C. de Klerk, Jerzy Adamski, Hugh Lemonde, Peter T. Clayton, D Cuebas, Ronald J. A. Wanders	1998	122
13	Quantitative plasma acylcarnitine analysis using electrospray tandem mass spectrometry for the diagnosis of organic acidaemias and fatty acid oxidation defects Journal of Inherited Metabolic Disease ·P. Vreken, A. E. M. van Lint, Albert H. Bootsma, Henk Overmars, Ronald J. A. Wanders, A. H. van Gennip	1999	113
14	Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects British Journal of Clinical Pharmacology ·Susan A. Ridge, Julieann Sludden, Oliver E. Brown, Leigh Robertson, Xiaoxiong Wei, Andrea Sapone, Pedro M. Fernández‐Salguero, Frank J. Gonzalez, P. Vreken, André B. P. Kuilenburg, Albert H. Gennip, Howard L. McLeod	1998	105
15	Heterozygosity for a point mutation in an invariant splice donor site of dihydropyrimidine dehydrogenase and severe 5-fluorouracil related toxicity European Journal of Cancer ·André B. P. Kuilenburg, P. Vreken, L.V.A.M. Beex, Rutger Meinsma, Henk van Lenthe, Ronney A. De Abreu, Albert H. Gennip	1997	90
16	Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage Human Molecular Genetics ·Isidró Ferrer, Josef P. Kapfhammer, C. Hindelang, Stephan Kemp, N. Troffer-Charlier, Vania Broccoli, Noëlle Callyzot, P. A. W. Mooyer, J. J. M. Selhorst, P. Vreken, Ronald J. A. Wanders, Jean‐Louis Mandel, Aurora Pujol	2005	86
17	Cardiolipin deficiency in x-linked cardioskeletal myopathy and neutropenia (barth syndrome, mim 302060): a study in cultured skin fibroblasts The Journal of Pediatrics ·Fredoen Valianpour, Ronald J. A. Wanders, Henk Overmars, P. Vreken, Albert H. Gennip, Frank Baas, Barbara Plecko, René Santer, Kolja Becker, P. G. Barth	2002	86
18	The rate-limiting step in yeast PGK1 mRNA degradation is an endonucleolytic cleavage in the 3'-terminal part of the coding region. Molecular and Cellular Biology ·P. Vreken, Hendrik A. Raué	1992	86
19	Inborn errors of pyrimidine degradation: Clinical, biochemical and molecular aspects Journal of Inherited Metabolic Disease ·Albert H. Gennip, N. G. G. M. Abeling, P. Vreken, André B. P. Kuilenburg	1997	85
20	A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency Journal of Inherited Metabolic Disease ·P. Vreken, André B. P. Kuilenburg, Rutger Meinsma, Gerrit Smit, H. D. Bakker, Ronney A. De Abreu, Albert H. Gennip	1996	81

About P. Vreken

P. Vreken is a scholar working on Molecular Biology, Clinical Biochemistry, Oncology, Pediatrics, Perinatology and Child Health and Physiology, having authored 81 papers that have together received 4.6k indexed citations. Recurring topics across this work include Metabolism and Genetic Disorders (38 papers), Biochemical and Molecular Research (25 papers), Peroxisome Proliferator-Activated Receptors (23 papers), Neonatal Health and Biochemistry (9 papers), Mitochondrial Function and Pathology (9 papers), Colorectal Cancer Treatments and Studies (8 papers), RNA modifications and cancer (8 papers) and Cancer therapeutics and mechanisms (6 papers). The work is most often cited by research in Clinical Biochemistry (1.1k citations), Biochemistry (328 citations), Molecular Biology (3.0k citations), Oncology (907 citations) and Physiology (510 citations). P. Vreken has collaborated with scholars based in Netherlands, United Kingdom and United States. Frequent co-authors include Ronald J. A. Wanders, André B. P. Kuilenburg, Hans R. Waterham, A. H. van Gennip, Albert H. Gennip, P. G. Barth, Sacha Ferdinandusse, Ronney A. De Abreu, Rutger Meinsma and E.G. van Grunsven. Their work appears in journals such as Journal of Inherited Metabolic Disease, Advances in experimental medicine and biology, Biochemical Society Transactions, Journal of Lipid Research and The Journal of Pediatrics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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