Nigel Austin

1.9k citations

24 papers · 727 · h-index 14

Impact in

Endocrine and Autonomic Systems top 10%
- Circadian rhythm and melatonin
Cellular and Molecular Neuroscience top 10%
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research

Papers in

Molecular Biology 17
- Receptor Mechanisms and Signaling 9
- Chemical Synthesis and Analysis 3
Cellular and Molecular Neuroscience 9
- Neuroscience and Neuropharmacology Research 5
- Neurotransmitter Receptor Influence on Behavior 4

Co-authors: Philip D. Jeffrey (7 shared papers)Michael S. Hadley (6 shared papers)Gary Tresadern (3 shared papers)Frederik Rombouts (4 shared papers)Andrés A. Trabanco (4 shared papers)Kevin M. Thewlis (6 shared papers)Fulgencio Tovar (1 shared paper)Geoffrey Stemp (6 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Journal of Medicinal Chemistry (4 papers)ACS Medicinal Chemistry Letters (3 papers)Xenobiotica (3 papers)Naunyn-Schmiedeberg s Archives of Pharmacology (1 paper)
Partner nations: United Kingdom Belgium United States

In The Last Decade

Nigel Austin

23 papers receiving 700 citations

Peers

Countries citing papers authored by Nigel Austin

Since Specialization

Citations

This map shows the geographic impact of Nigel Austin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nigel Austin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nigel Austin more than expected).

Fields of papers citing papers by Nigel Austin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nigel Austin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nigel Austin. The network helps show where Nigel Austin may publish in the future.

Co-authors

The 25 scholars most cited alongside Nigel Austin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Nigel Austin Line = papers co-authored together Nigel Austin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 24 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor Bioorganic & Medicinal Chemistry Letters ·Roderick A. Porter, Wai N. Chan, Steven Coulton, Amanda Johns, Michael S. Hadley, Katherine L. Widdowson, Jeffrey C. Jerman, Stephen Brough, Martyn C. Coldwell, Darren Smart, Frances Jewitt, Philip D. Jeffrey, Nigel Austin	2001	119
2	Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D₃ Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat Journal of Medicinal Chemistry ·Geoffrey Stemp, Tracey Ashmeade, Clive L. Branch, Michael S. Hadley, A. Jacqueline Hunter, Christopher N. Johnson, David J. Nash, Kevin M. Thewlis, Antonio Vong, Nigel Austin, Philip D. Jeffrey, Kim Y. Avenell, Izzy Boyfield, Jim J. Hagan, Derek N. Middlemiss, Charlie Reavill, Graham J. Riley, Carole Routledge, Martyn Wood	2000	110
3	Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example Journal of Medicinal Chemistry ·Frederik Rombouts, Fulgencio Tovar, Nigel Austin, Gary Tresadern, Andrés A. Trabanco	2015	73
4	Comparison between intraperitoneal and subcutaneous phencyclidine administration in Sprague–Dawley rats: A locomotor activity and gene induction study Progress in Neuro-Psychopharmacology and Biological Psychiatry ·Mikhail Kalinichev, Melanie J. Robbins, Elizabeth M. Hartfield, Peter R. Maycox, Susan H. Moore, Kevin M. Savage, Nigel Austin, Declan N.C. Jones	2007	65
5	Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators Journal of Medicinal Chemistry ·Simon E. Ward, Mark H Harries, Laura Aldegheri, Nigel Austin, Stuart P. Ballantine, Elisa Ballini, Daniel M. Bradley, B.D. Bax, Brian Clarke, A. I. Harris, Stephen A. Harrison, Rosemary A. Melarange, Claudette Mookherjee, J. Mosley, Gianni Dal Negro, Beatrice Oliosi, Kathrine J. Smith, Kevin M. Thewlis, P.M. Woollard, Shahnaz P. Yusaf	2010	57
6	Pharmacokinetics of the novel, high-affinity and selective dopamine D3 receptor antagonist SB-277011 in rat, dog and monkey:in vitro/in vivocorrelation and the role of aldehyde oxidase Xenobiotica ·Nigel Austin, S. J. Baldwin, Leanne Cutler, Nigel Deeks, Pamela J. Kelly, Mike Nash, Carole Shardlow, Geoffrey Stemp, Kevin M. Thewlis, A. D. Ayrton, Philip D. Jeffrey	2001	52
7	The relationship between sodium channel inhibition and anticonvulsant activity in a model of generalised seizure in the rat Epilepsy Research ·Charles H. Large, Mikhail Kalinichev, Adam Lucas, Corrado Carignani, Andrea M. Bradford, Nicoletta Garbati, Ilaria Sartori, Nigel Austin, Alberto Ruffo, Declan N.C. Jones, Giuseppe Alvaro, Kevin D. Read	2009	36
8	Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads ACS Medicinal Chemistry Letters ·Daniel Oehlrich, Aldo Peschiulli, Gary Tresadern, Michiel Van Gool, Juan A. Vega, Ana Isabel de Lucas, Sergio A. Alonso de Diego, Hana Prokopcová, Nigel Austin, Sven Van Brandt, Michel Surkyn, Michel De Cleyn, Ann Vos, Frederik Rombouts, Gregor J. Macdonald, Dieder Moechars, Harrie J. M. Gijsen, Andrés A. Trabanco	2019	26
9	Metabolism and disposition of¹⁴C-granisetron in rat, dog and man after intravenous and oral dosing Xenobiotica ·S. E. Clarke, Nigel Austin, J. C. Bloomer, R. E. Haddock, Frank C. Higham, F. J. Hollis, Mike Nash, P. C. Shardlow, Tim Tasker, F. R. Woods, Graham Allen	1994	24
10	The effect of SB-236057-A, a selective 5-HT 1B receptor inverse agonist, on in vivo extracellular 5-HT levels in the freely-moving guinea-pig Naunyn-Schmiedeberg s Archives of Pharmacology ·C. Roberts, Paula D. Hatcher, Jim J. Hagan, Nigel Austin, Philip D. Jeffrey, Paul Wyman, Laramie M. Gaster, Carol Routledge, Derek N. Middlemiss	2000	22
11	The design of 8,8-Dimethyl[1,6]naphthyridines as potential anticonvulsant agents Bioorganic & Medicinal Chemistry Letters ·Nigel Austin, Michael S. Hadley, John D. Harling, Frank P. Harrington, Gregor J. Macdonald, Darren J. Mitchell, Graham J. Riley, Tania O. Stean, Geoffrey Stemp, Sharon C. Stratton, Mervyn Thompson, Neil Upton	2003	22
12	The disposition of gemifloxacin, a new fluoroquinolone antibiotic, in rats and dogs. PubMed ·J. V. Ramji, Nigel Austin, G. W. Boyle, M H Chalker, G.F. Duncan, Amanda J. Fairless, F. J. Hollis, David McDonnell, Timothy J Musick, P. C. Shardlow	2001	19
13	Novel 2,3,4,5-tetrahydro-1H-3-benzazepines with high affinity and selectivity for the dopamine D3 receptor Bioorganic & Medicinal Chemistry Letters ·Nigel Austin, Kim Y. Avenell, Izzy Boyfield, Clive L. Branch, Michael S. Hadley, Philip D. Jeffrey, Christopher N. Johnson, Gregor J. Macdonald, David J. Nash, Graham J. Riley, Alexander B. Smith, Geoffrey Stemp, Kevin M. Thewlis, Antonio Vong, Martyn Wood	2000	15
14	Novel 1,2,3,4-tetrahydroisoquinolines with high affinity and selectivity for the dopamine D3 receptor Bioorganic & Medicinal Chemistry Letters ·Nigel Austin, Kim Y. Avenell, Izzy Boyfield, Clive L. Branch, Martyn C. Coldwell, Michael S. Hadley, Philip D. Jeffrey, Amana Johns, Christopher N. Johnson, David J. Nash, Graham J. Riley, Stephen A. Smith, Rachel Stacey, Geoffrey Stemp, Kevin M. Thewlis, Antonio Vong	1999	15
15	Design and synthesis of novel 2,3-dihydro-1H-isoindoles with high affinity and selectivity for the dopamine D3 receptor Bioorganic & Medicinal Chemistry Letters ·Nigel Austin, Kim Y. Avenell, Izzy Boyfield, Clive L. Branch, Michael S. Hadley, Philip D. Jeffrey, Christopher N. Johnson, Gregor J. Macdonald, David J. Nash, Graham J. Riley, Alexander B. Smith, Geoffrey Stemp, Kevin M. Thewlis, Antonio Vong, Martyn Wood	2001	13
16	Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors Toward a Clinical Candidate Journal of Medicinal Chemistry ·Harrie J. M. Gijsen, Sergio A. Alonso de Diego, Michel De Cleyn, Aránzazu García-Molina, Gregor J. Macdonald, Carolina Martínez‐Lamenca, Daniel Oehlrich, Hana Prokopcová, Frederik Rombouts, Michel Surkyn, Andrés A. Trabanco, Sven Van Brandt, Dries Van den Bossche, Michiel Van Gool, Nigel Austin, Herman Borghys, Deborah Dhuyvetter, Diederik Moechars	2018	11
17	Potentiation of the anticonvulsant efficacy of sodium channel inhibitors by an NK1‐receptor antagonist in the rat Epilepsia ·Mikhail Kalinichev, Andrea M. Bradford, Silvia Bison, Adam Lucas, Ilaria Sartori, Nicoletta Garbati, Filippo Andreetta, Simon T. Bate, Nigel Austin, Declan N.C. Jones, Kevin D. Read, Giuseppe Alvaro, Charles H. Large	2010	10
18	The Identification of GPR52 Agonist HTL0041178, a Potential Therapy for Schizophrenia and Related Psychiatric Disorders ACS Medicinal Chemistry Letters ·Simon Poulter, Nigel Austin, Rachel Armstrong, Matt Barnes, S.J. Bucknell, Alícia P. Higueruelo, Joydeep Banerjee, Andy Mead, Richard F. Mould, Cliona MacSweeney, Alistair O’Brien, Lisa A. Stott, Stephen P. Watson	2023	9
19	Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease Bioorganic & Medicinal Chemistry Letters ·Tianbao Lu, Peter J. Connolly, Ulrike Philippar, Weimei Sun, Maxwell D. Cummings, Kent Barbay, Luc Gys, Luc Van Nuffel, Nigel Austin, Mariette Bekkers, Fang Shen, Ann Cai, Ricardo M. Attar, Lieven Meerpoel, James L. Edwards	2019	9
20	A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1 Inhibitor Elicits Sustained Reduction of Amyloid β In Vivo ACS Medicinal Chemistry Letters ·Aldo Peschiulli, Daniel Oehlrich, Michiel Van Gool, Nigel Austin, Sven Van Brandt, Michel Surkyn, Michel De Cleyn, Ann Vos, Gary Tresadern, Frederik Rombouts, Gregor J. Macdonald, Diederik Moechars, Andrés A. Trabanco, Harrie J. M. Gijsen	2021	7

About Nigel Austin

Nigel Austin is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Organic Chemistry, Pharmacology and Physiology, having authored 24 papers that have together received 727 indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (9 papers), Neuroscience and Neuropharmacology Research (5 papers), Pharmacogenetics and Drug Metabolism (4 papers), Neurotransmitter Receptor Influence on Behavior (4 papers), Chemical Synthesis and Analysis (3 papers), Drug Transport and Resistance Mechanisms (3 papers), Alzheimer's disease research and treatments (2 papers) and Computational Drug Discovery Methods (2 papers). The work is most often cited by research in Endocrine and Autonomic Systems (104 citations), Cellular and Molecular Neuroscience (253 citations), Biological Psychiatry (19 citations), Cognitive Neuroscience (134 citations) and Experimental and Cognitive Psychology (89 citations). Nigel Austin has collaborated with scholars based in United Kingdom, Belgium and United States. Frequent co-authors include Philip D. Jeffrey, Michael S. Hadley, Gary Tresadern, Frederik Rombouts, Andrés A. Trabanco, Kevin M. Thewlis, Fulgencio Tovar, Geoffrey Stemp, Declan N.C. Jones and Mikhail Kalinichev. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Xenobiotica and Naunyn-Schmiedeberg s Archives of Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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