Tatsuki Koike

889 citations

41 papers · 662 · h-index 14

Impact in

Endocrine and Autonomic Systems top 10%
- Circadian rhythm and melatonin
Organic Chemistry top 10%
- Catalytic C–H Functionalization Methods
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
- Chemical synthesis and alkaloids

Papers in

Molecular Biology 16
- Steroid Chemistry and Biochemistry 6
Endocrine and Autonomic Systems 10
- Circadian rhythm and melatonin 7

Co-authors: Takafumi Takai (9 shared papers)Yasutaka Hoashi (8 shared papers)Kazuo Tachibana (2 shared papers)Ryuichi Sakai (2 shared papers)Makoto Sasaki (2 shared papers)Osamu Uchikawa (5 shared papers)Keisuke Hirai (3 shared papers)Takashi Ishikawa (4 shared papers)
Journals: Journal of Medicinal Chemistry (11 papers)Tetrahedron Letters (4 papers)Bioorganic & Medicinal Chemistry (3 papers)Scientific Reports (3 papers)Sleep Medicine (2 papers)
Partner nations: Japan United States China

In The Last Decade

Tatsuki Koike

38 papers receiving 653 citations

Peers

Countries citing papers authored by Tatsuki Koike

Since Specialization

Citations

This map shows the geographic impact of Tatsuki Koike's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tatsuki Koike with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tatsuki Koike more than expected).

Fields of papers citing papers by Tatsuki Koike

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tatsuki Koike. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tatsuki Koike. The network helps show where Tatsuki Koike may publish in the future.

Co-authors

The 25 scholars most cited alongside Tatsuki Koike, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tatsuki Koike Line = papers co-authored together Tatsuki Koike links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 41 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Isolation, Structure Determination, and Synthesis of Neodysiherbaine A, a New Excitatory Amino Acid from a Marine Sponge Organic Letters ·Ryuichi Sakai, Tatsuki Koike, Makoto Sasaki, Keiko Shimamoto, Chie Oiwa, Atsuko Yano, Katsuji Suzuki, Kazuo Tachibana, Hisao Kamiya	2001	79
2	Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice Scientific Reports ·Toshiya Nishi, Shinichi Kondo, Maki Miyamoto, Sayuri Watanabe, Shigeo Hasegawa, Shigeru Kondo, Jason K. Yano, Etsurou Watanabe, Tsuyoshi Ishi, Masato Yoshikawa, Haruhi Kamisaki Ando, William Farnaby, Shinji Fujimoto, Eiji Sunahara, Momoko Ohori, Matthew J. During, Takanobu Kuroita, Tatsuki Koike	2020	61
3	Synthesis of a Novel Series of Tricyclic Dihydrofuran Derivatives: Discovery of 8,9-Dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as Melatonin Receptor (MT₁/MT₂) Ligands Journal of Medicinal Chemistry ·Tatsuki Koike, Takafumi Takai, Yasutaka Hoashi, (unknown), Yohei Kosugi, Masato Nakashima, Shin-ichi Yoshikubo, Keisuke Hirai, Osamu Uchikawa	2011	58
4	A compact planar positron imaging system Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment ·Hiroshi Uchida, Takashi Okamoto, T. Ohmura, Katsuji Shimizu, N. Satoh, Tatsuki Koike, T. Yamashita	2003	55
5	Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors Journal of Medicinal Chemistry ·Jumpei Aida, Makoto Fushimi, Tomokazu Kusumoto, Hideyuki Sugiyama, Naoto Arimura, Shuhei Ikeda, Masako Sasaki, Satoshi Sogabe, Kazunobu Aoyama, Tatsuki Koike	2018	48
6	1,6-Dihydro-2H-indeno[5,4-b]furan Derivatives: Design, Synthesis, and Pharmacological Characterization of a Novel Class of Highly Potent MT₂-Selective Agonists Journal of Medicinal Chemistry ·Tatsuki Koike, Yasutaka Hoashi, Takafumi Takai, (unknown), Nobuhito Yukuhiro, Takashi Ishikawa, Keisuke Hirai, Osamu Uchikawa	2011	42
7	Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H) Journal of Medicinal Chemistry ·Tatsuki Koike, Masato Yoshikawa, Haruhi Kamisaki Ando, William Farnaby, Toshiya Nishi, Etsurou Watanabe, Jason K. Yano, Maki Miyamoto, Shigeru Kondo, Tsuyoshi Ishii, Takanobu Kuroita	2021	37
8	Total synthesis of (−)-dysiherbaine, a novel neuroexcitotoxic amino acid Tetrahedron Letters ·Makoto Sasaki, Tatsuki Koike, Ryuichi Sakai, Kazuo Tachibana	2000	34
9	Design, Synthesis, and Evaluation of (4R)-1-{3-[2-(¹⁸F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([¹⁸F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase Journal of Medicinal Chemistry ·Yasushi Hattori, Kazunobu Aoyama, Jun Maeda, Naoto Arimura, Yasuko Takahashi, Masako Sasaki, Masayuki Fujinaga, Chie Seki, Yuji Nagai, Kazunori Kawamura, Tomoteru Yamasaki, Ming‐Rong Zhang, Makoto Higuchi, Tatsuki Koike	2019	24
10	Molecular mechanism of the wake-promoting agent TAK-925 Nature Communications ·Jie Yin, Yanyong Kang, Aaron P. McGrath, Karen Chapman, Megan Sjodt, Eiji Kimura, Atsutoshi Okabe, Tatsuki Koike, Yuhei Miyanohana, Yūji Shimizu, Rameshu Rallabandi, Peng Lian, Xiao‐chen Bai, Mack Flinspach, Jef K. De Brabander, Daniel M. Rosenbaum	2022	20
11	TAK-994, a Novel Orally Available Brain-Penetrant Orexin 2 Receptor-Selective Agonist, Suppresses Fragmentation of Wakefulness and Cataplexy-Like Episodes in Mouse Models of Narcolepsy Journal of Pharmacology and Experimental Therapeutics ·Takashi Ishikawa, Hiroe Hara, Ayumi Kawano, Kimio Tohyama, (unknown), Yuhei Miyanohana, Tatsuki Koike, Haruhide Kimura	2023	20
12	Pharmacological properties of a novel and potent γ-secretase modulator as a therapeutic option for the treatment of Alzheimer’s disease Brain Research ·Koji Murakami, Tomomichi Watanabe, Tatsuki Koike, Makoto Kamata, Tomoko Igari, Shinichi Kondo	2015	17
13	Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators Bioorganic & Medicinal Chemistry Letters ·Takafumi Takai, Yasutaka Hoashi, Yoshihide Tomata, Sachie Morimoto, Minoru Nakamura, Tomomichi Watanabe, Tomoko Igari, Tatsuki Koike	2015	13
14	Synthesis of pyrazolo[1,5-a]pyridines by thermal intramolecular cyclization Tetrahedron Letters ·Yasutaka Hoashi, Takafumi Takai, Etsuo Kotani, Tatsuki Koike	2013	13
15	Preclinical characterization of [18F]T-008, a novel PET imaging radioligand for cholesterol 24-hydroxylase European Journal of Nuclear Medicine and Molecular Imaging ·Tatsuki Koike, Cristian Constantinescu, Shuhei Ikeda, Toshiya Nishi, Eiji Sunahara, Maki Miyamoto, Patricia E. Cole, Olivier Barret, David Alagille, Caroline Papin, Thomas Morley, Krista Fowles, John Seibyl, Gilles Tamagnan, Takanobu Kuroita	2021	12
16	Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators (Part 2) Bioorganic & Medicinal Chemistry ·Takafumi Takai, Tatsuki Koike, Minoru Nakamura, (unknown), Toshiro Yamashita, Naohiro Taya, Tetsuya Tsukamoto, Tomomichi Watanabe, Koji Murakami, Tomoko Igari, Makoto Kamata	2016	12
17	Synthesis of 4-aza analog of ramelteon: a novel tricyclic 1,6,7,8-tetrahydro-2H-cyclopenta[d]furo[2,3-b]pyridine derivative as melatonin receptor ligand Tetrahedron Letters ·Tatsuki Koike, Yasutaka Hoashi, Takafumi Takai, Osamu Uchikawa	2011	11
18	Discovery of a Novel and Brain-Penetrant O -GlcNAcase Inhibitor via Virtual Screening, Structure-Based Analysis, and Rational Lead Optimization Journal of Medicinal Chemistry ·Michiko Tawada, Makoto Fushimi, Kei Masuda, Huikai Sun, Noriko Uchiyama, Yohei Kosugi, Weston Lane, Richard Tjhen, Satoshi Endo, Tatsuki Koike	2021	10
19	Discovery of a Potent and Orally Bioavailable Melatonin Receptor Agonist Journal of Medicinal Chemistry ·Yasutaka Hoashi, Takafumi Takai, Yohei Kosugi, Masato Nakashima, (unknown), Keisuke Hirai, Osamu Uchikawa, Tatsuki Koike	2021	9
20	Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors Journal of Medicinal Chemistry ·Y. Kajita, Shuhei Ikeda, Masato Yoshikawa, Hiromi Fukuda, Etsurou Watanabe, Jason K. Yano, Weston Lane, Maki Miyamoto, Tsuyoshi Ishii, Toshiya Nishi, Tatsuki Koike	2022	8

About Tatsuki Koike

Tatsuki Koike is a scholar working on Molecular Biology, Endocrine and Autonomic Systems, Cognitive Neuroscience, Organic Chemistry and Surgery, having authored 41 papers that have together received 662 indexed citations. Recurring topics across this work include Sleep and Wakefulness Research (9 papers), Circadian rhythm and melatonin (7 papers), Steroid Chemistry and Biochemistry (6 papers), Alzheimer's disease research and treatments (5 papers), Cholesterol and Lipid Metabolism (5 papers), Hormonal Regulation and Hypertension (5 papers), Sleep and related disorders (5 papers) and Neuroscience and Neuropharmacology Research (4 papers). The work is most often cited by research in Endocrine and Autonomic Systems (74 citations), Organic Chemistry (227 citations), Pharmacology (114 citations), Pharmacology (43 citations) and Cellular and Molecular Neuroscience (88 citations). Tatsuki Koike has collaborated with scholars based in Japan, United States and China. Frequent co-authors include Takafumi Takai, Yasutaka Hoashi, Kazuo Tachibana, Ryuichi Sakai, Makoto Sasaki, Osamu Uchikawa, Keisuke Hirai, Takashi Ishikawa, Maki Miyamoto and Toshiya Nishi. Their work appears in journals such as Journal of Medicinal Chemistry, Tetrahedron Letters, Bioorganic & Medicinal Chemistry, Scientific Reports and Sleep Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Tatsuki Koike

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Tatsuki Koike

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About Tatsuki Koike

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