Michaela U. Gack

16.0k citations

79 papers · 8.4k · 4 hit papers · h-index 43

Impact in

Immunology top 0.2%
- interferon and immune responses
- Immune Response and Inflammation
Infectious Diseases top 0.5%
- Viral Infections and Vectors

Papers in

Immunology 58
- interferon and immune responses 55
- Immune Response and Inflammation 19
Molecular Biology 34
- Inflammasome and immune disorders 19
- RNA regulation and disease 6

Co-authors: Jan Rehwinkel (1 shared paper)Ying Chan (6 shared papers)Jae U. Jung (11 shared papers)Konstantin M. J. Sparrer (13 shared papers)Guanqun Liu (16 shared papers)Kyung‐Soo Inn (6 shared papers)Meredith E. Davis-Gardner (7 shared papers)Cindy Chiang (12 shared papers)
Journals: Journal of Virology (8 papers)Nature Communications (6 papers)Proceedings of the National Academy of Sciences (5 papers)Cell Host & Microbe (5 papers)PLoS Pathogens (5 papers)
Partner nations: United States Germany Japan

In The Last Decade

Michaela U. Gack

78 papers receiving 8.4k citations

Michaela U. Gack's Hit Papers

align trajectories log scale

ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity 2021 · 219 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Nature Microbiology
2020 Nature reviews. Immunology
2009 Cell Host & Microbe
2008 Nature Cell Biology

Peers

Countries citing papers authored by Michaela U. Gack

Since Specialization

Citations

This map shows the geographic impact of Michaela U. Gack's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michaela U. Gack with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michaela U. Gack more than expected).

Fields of papers citing papers by Michaela U. Gack

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michaela U. Gack. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michaela U. Gack. The network helps show where Michaela U. Gack may publish in the future.

Co-authors

The 25 scholars most cited alongside Michaela U. Gack, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michaela U. Gack Line = papers co-authored together Michaela U. Gack links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 79 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	RIG-I-like receptors: their regulation and roles in RNA sensing Nature reviews. Immunology ·Jan Rehwinkel, Michaela U. Gack Hit paper breakdown →	2020	1137
2	Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I Cell Host & Microbe ·Michaela U. Gack, Randy A. Albrecht, Tomohiko Urano, Kyung‐Soo Inn, I‐Chueh Huang, Elena Carnero, Michael Farzan, Satoshi Inoue, Jae U. Jung, Adolfo García‐Sastre Hit paper breakdown →	2009	722
3	Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking Nature Cell Biology ·Chengyu Liang, Jong‐Soo Lee, Kyung‐Soo Inn, Michaela U. Gack, Qinglin Li, Esteban A. Roberts, Isabelle Vergne, Vojo Deretić, Pinghui Feng, Chihiro Akazawa, Jae U. Jung Hit paper breakdown →	2008	628
4	Viral evasion of intracellular DNA and RNA sensing Nature Reviews Microbiology ·Ying Chan, Michaela U. Gack	2016	335
5	Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate–Dependent Translocase on Double-Stranded RNA Science ·Sua Myong, Sheng Cui, Peter V. Cornish, Axel Kirchhofer, Michaela U. Gack, Jae U. Jung, Karl‐Peter Hopfner, Taekjip Ha	2009	308
6	Dysregulation of type I interferon responses in COVID-19 Nature reviews. Immunology ·Dhiraj Acharya, Guanqun Liu, Michaela U. Gack	2020	293
7	Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein PLoS Pathogens ·Ricardo Rajsbaum, Randy A. Albrecht, May K. Wang, Natalya P. Maharaj, Gijs A. Versteeg, Estanislao Nistal‐Villán, Adolfo García‐Sastre, Michaela U. Gack	2012	261
8	TRIM Proteins and Their Roles in Antiviral Host Defenses Annual Review of Virology ·Michiel van Gent, Konstantin M. J. Sparrer, Michaela U. Gack	2018	260
9	Dephosphorylation of the RNA Sensors RIG-I and MDA5 by the Phosphatase PP1 Is Essential for Innate Immune Signaling Immunity ·Effi Wies, May K. Wang, Natalya P. Maharaj, Kan Chen, Shenghua Zhou, Robert W. Finberg, Michaela U. Gack	2013	250
10	ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity Nature Microbiology ·Guanqun Liu, Jung‐Hyun Lee, Zachary M. Parker, Dhiraj Acharya, Jessica J. Chiang, Michiel van Gent, William Riedl, Meredith E. Davis-Gardner, Effi Wies, Cindy Chiang, Michaela U. Gack Hit paper breakdown →	2021	219
11	Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction Proceedings of the National Academy of Sciences ·Michaela U. Gack, Axel Kirchhofer, Young C. Shin, Kyung‐Soo Inn, Chengyu Liang, Sheng Cui, Sua Myong, Taekjip Ha, Karl‐Peter Hopfner, Jae U. Jung	2008	216
12	Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity Nature Immunology ·Jessica J. Chiang, Konstantin M. J. Sparrer, Michiel van Gent, Charlotte Lässig, Teng Huang, Nikolaus Osterrieder, Karl‐Peter Hopfner, Michaela U. Gack	2017	191
13	Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction Molecular Cell ·Kyung‐Soo Inn, Michaela U. Gack, Fuminori Tokunaga, Mude Shi, (unknown), Kazuhiro Iwaï, Jae U. Jung	2011	176
14	TRIM23 mediates virus-induced autophagy via activation of TBK1 Nature Microbiology ·Konstantin M. J. Sparrer, Sebastian Gableske, Matthew A. Zurenski, Zachary M. Parker, Florian Full, Gavin J. Baumgart, Jiro Kato, Gustavo Pacheco–Rodriguez, Chengyu Liang, Owen Pornillos, Joel Moss, Martha Vaughan, Michaela U. Gack	2017	169
15	Ubiquitination in the antiviral immune response Virology ·Meredith E. Davis-Gardner, Michaela U. Gack	2015	148
16	RIG-I-like receptor regulation in virus infection and immunity Current Opinion in Virology ·Ying Chan, Michaela U. Gack	2015	147
17	A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19 PLoS Biology ·Yadi Zhou, Yuan Hou, Jiayu Shen, Reena Mehra, Asha Kallianpur, Daniel A. Culver, Michaela U. Gack, Samar Farha, Joe Zein, Suzy Comhair, Claudio Fiocchi, Thaddeus S. Stappenbeck, Timothy Chan, Charis Eng, Jae U. Jung, Lara Jehi, Serpil C. Erzurum, Feixiong Cheng	2020	134
18	The Ubiquitin-Specific Protease USP15 Promotes RIG-I–Mediated Antiviral Signaling by Deubiquitylating TRIM25 Science Signaling ·Eva-Katharina Pauli, Ying Chan, Meredith E. Davis-Gardner, Sebastian Gableske, May K. Wang, Katharina F. Feister, Michaela U. Gack	2014	133
19	Post-translational Control of Intracellular Pathogen Sensing Pathways Trends in Immunology ·Cindy Chiang, Michaela U. Gack	2016	121
20	The Human Papillomavirus E6 Oncoprotein Targets USP15 and TRIM25 To Suppress RIG-I-Mediated Innate Immune Signaling Journal of Virology ·Cindy Chiang, Eva-Katharina Pauli, Jennifer Biryukov, Katharina F. Feister, Melissa Meng, Elizabeth White, Karl Münger, Peter M. Howley, Craig Meyers, Michaela U. Gack	2017	113

About Michaela U. Gack

Michaela U. Gack is a scholar working on Immunology, Molecular Biology, Epidemiology, Infectious Diseases and Oncology, having authored 79 papers that have together received 8.4k indexed citations. Recurring topics across this work include interferon and immune responses (55 papers), Inflammasome and immune disorders (19 papers), Immune Response and Inflammation (19 papers), Viral Infections and Vectors (10 papers), Cytomegalovirus and herpesvirus research (8 papers), Mosquito-borne diseases and control (8 papers), RNA regulation and disease (6 papers) and Herpesvirus Infections and Treatments (6 papers). The work is most often cited by research in Immunology (5.0k citations), Infectious Diseases (1.9k citations), Epidemiology (2.3k citations), Virology (233 citations) and Molecular Biology (3.4k citations). Michaela U. Gack has collaborated with scholars based in United States, Germany and Japan. Frequent co-authors include Jan Rehwinkel, Ying Chan, Jae U. Jung, Konstantin M. J. Sparrer, Guanqun Liu, Kyung‐Soo Inn, Meredith E. Davis-Gardner, Cindy Chiang, Michiel van Gent and Dhiraj Acharya. Their work appears in journals such as Journal of Virology, Nature Communications, Proceedings of the National Academy of Sciences, Cell Host & Microbe and PLoS Pathogens.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Michaela U. Gack

Michaela U. Gack's Hit Papers

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