Michael J. Eck

48.3k citations
179 papers · 40.6k · 15 hit papers · h-index 84

Impact in

Papers in

    • HER2/EGFR in Cancer Research 24
    • Cytokine Signaling Pathways and Interactions 17
    • Protein Kinase Regulation and GTPase Signaling 26
    • Cancer therapeutics and mechanisms 22
    • Melanoma and MAPK Pathways 12

Michael J. Eck

173 papers receiving 39.3k citations

Michael J. Eck's Hit Papers

Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors 2016 · 748 citations
7480+10+20Years since publication2.5k5.0k7.5k

Peers

Michael J. Eck
Comparison fields: 5 of 158
  • Oncology 12.9k
  • Pulmonary and Respiratory Medicine 12.6k
  • Genetics 3.7k
  • Cancer Research 4.6k
  • Molecular Biology 20.8k
Replace Nathanael S. Gray with:
Nathanael S. Gray United States
Neal X. Rosen United States
Titus J. Boggon United States
Julian Downward United Kingdom
Kwok‐Kin Wong United States
Frank P. McCormick United States
Robert S. Kerbel Canada
Grant A. McArthur Australia
David C. Lyden United States
David Solit United States
Michael J. Eck relative to Nathanael S. Gray United States Nathanael S. Gray's profile →
Citations per field
00.5×1.5×
Nathanael S. Gray · 1×
Citations per year

Countries citing papers authored by Michael J. Eck

Since Specialization
Citations

This map shows the geographic impact of Michael J. Eck's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael J. Eck with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael J. Eck more than expected).

Fields of papers citing papers by Michael J. Eck

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael J. Eck. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael J. Eck. The network helps show where Michael J. Eck may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael J. Eck, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael J. Eck Line = papers co-authored together Michael J. Eck links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 179 papers — load more, or switch the sort, to bring in the rest.

#Work
1
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
Hit paper breakdown →
20048145
2
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
Hit paper breakdown →
20053445
3
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
Hit paper breakdown →
20052544
4
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
Hit paper breakdown →
20081737
5
Three-dimensional structure of the tyrosine kinase c-Src
Hit paper breakdown →
19971234
6
Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity
Hit paper breakdown →
2007983
7
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
Hit paper breakdown →
2009884
8
Crystal Structure of the Tyrosine Phosphatase SHP-2
Hit paper breakdown →
1998849
9
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
Hit paper breakdown →
1995837
10
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors
Hit paper breakdown →
2016748
11
Crystal Structures of c-Src Reveal Features of Its Autoinhibitory Mechanism
Hit paper breakdown →
1999742
12
Mechanism and Function of Formins in the Control of Actin Assembly
Hit paper breakdown →
2007657
13 2004572
14
Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer
Hit paper breakdown →
2013493
15 1989457
16 2000456
17 1993445
18 2004436
19 1989424
20 2002402

About Michael J. Eck

Michael J. Eck is a scholar working on Oncology, Molecular Biology, Cell Biology, Pulmonary and Respiratory Medicine and Immunology, having authored 179 papers that have together received 40.6k indexed citations. Recurring topics across this work include Lung Cancer Treatments and Mutations (36 papers), Protein Kinase Regulation and GTPase Signaling (26 papers), HER2/EGFR in Cancer Research (24 papers), Cancer therapeutics and mechanisms (22 papers), Cellular Mechanics and Interactions (21 papers), Cytokine Signaling Pathways and Interactions (17 papers), Monoclonal and Polyclonal Antibodies Research (17 papers) and Melanoma and MAPK Pathways (12 papers). The work is most often cited by research in Oncology (12.9k citations), Pulmonary and Respiratory Medicine (12.6k citations), Genetics (3.7k citations), Cancer Research (4.6k citations) and Molecular Biology (20.8k citations). Michael J. Eck has collaborated with scholars based in United States, Germany and Switzerland. Frequent co-authors include Titus J. Boggon, Matthew Meyerson, Pasi Antero Janne, Heidi E. Greulich, Bruce Evan Johnson, Cai‐Hong Yun, Wenqing Xu, Stephen C. Harrison, Steven E. Shoelson and Stephen R. Sprang. Their work appears in journals such as Proceedings of the National Academy of Sciences, Nature, Journal of Biological Chemistry, Nature Structural & Molecular Biology and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact