Marcia E. Newcomer

7.0k citations

105 papers · 6.1k · 1 hit paper · h-index 42

Impact in

Biochemistry top 0.5%
- Antioxidant Activity and Oxidative Stress
- Eicosanoids and Hypertension Pharmacology
Toxicology top 1%

Papers in

Molecular Biology 74
- Retinoids in leukemia and cellular processes 22
- Biochemical and Molecular Research 8
Biochemistry 16
- Antioxidant Activity and Oxidative Stress 8
- Amino Acid Enzymes and Metabolism 8

Co-authors: T. Alwyn Jones (7 shared papers)ALAN R. BRASH (12 shared papers)Nathaniel C. Gilbert (18 shared papers)Sandra W. Cowan (2 shared papers)David B. Neau (11 shared papers)Sue G. Bartlett (11 shared papers)David Eng-Hui Ong (8 shared papers)Svetlana V. Pakhomova (22 shared papers)
Journals: Journal of Biological Chemistry (22 papers)Biochemistry (13 papers)Protein Science (10 papers)Biochemical and Biophysical Research Communications (4 papers)Journal of Molecular Biology (4 papers)
Partner nations: United States Sweden Germany

In The Last Decade

Marcia E. Newcomer

105 papers receiving 5.9k citations

Marcia E. Newcomer's Hit Papers

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The structure of β-lactoglobulin and its similarity to plasma retinol-binding protein 1986 · 817 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

1986 Nature

Peers

Countries citing papers authored by Marcia E. Newcomer

Since Specialization

Citations

This map shows the geographic impact of Marcia E. Newcomer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marcia E. Newcomer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marcia E. Newcomer more than expected).

Fields of papers citing papers by Marcia E. Newcomer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marcia E. Newcomer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marcia E. Newcomer. The network helps show where Marcia E. Newcomer may publish in the future.

Co-authors

The 25 scholars most cited alongside Marcia E. Newcomer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Marcia E. Newcomer Line = papers co-authored together Marcia E. Newcomer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 105 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The structure of β-lactoglobulin and its similarity to plasma retinol-binding protein Nature ·Miroslav Z. Papiz, Lindsay Sawyer, Elias Eliopoulos, Anthony C.T. North, J. B. C. Findlay, Asipu Sivaprasadarao, T. Alwyn Jones, Marcia E. Newcomer Hit paper breakdown →	1986	817
2	The Structure of Human 5-Lipoxygenase Science ·Nathaniel C. Gilbert, Sue G. Bartlett, Maria T. Waight, David B. Neau, William E. Boeglin, ALAN R. BRASH, Marcia E. Newcomer	2011	376
3	The three‐dimensional structure of retinol‐binding protein. The EMBO Journal ·Marcia E. Newcomer, T. Alwyn Jones, Johan Åqvist, Johan Sundelin, Ulf Eriksson, Lars Rask, Per A. Peterson	1984	373
4	Crystallographic refinement of human serum retinol binding protein at 2Å resolution Proteins Structure Function and Bioinformatics ·Sandra W. Cowan, Marcia E. Newcomer, T. Alwyn Jones	1990	286
5	The structural basis for specificity in lipoxygenase catalysis Protein Science ·Marcia E. Newcomer, ALAN R. BRASH	2014	183
6	Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products Nature Chemical Biology ·Nathaniel C. Gilbert, Jana Gerstmeier, Erin E. Schexnaydre, Friedemann Börner, Ulrike Garscha, David B. Neau, Oliver Werz, Marcia E. Newcomer	2020	182
7	Crystallographic Studies on a Family of Cellular Lipophilic Transport Proteins Journal of Molecular Biology ·Sandra W. Cowan, Marcia E. Newcomer, T. Alwyn Jones	1993	172
8	The Structure of Human Retinol-Binding Protein (RBP) with Its Carrier Protein Transthyretin Reveals an Interaction with the Carboxy Terminus of RBP, Biochemistry ·Helen M. Naylor, Marcia E. Newcomer	1999	160
9	Plasma retinol binding protein: structure and function of the prototypic lipocalin Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Marcia E. Newcomer, David Eng-Hui Ong	2000	149
10	Conversion of human 5‐lipoxygenase to a 15‐lipoxygenase by a point mutation to mimic phosphorylation at Serine‐663 The FASEB Journal ·Nathaniel C. Gilbert, Zhe Rui, David B. Neau, Maria T. Waight, Sue G. Bartlett, William E. Boeglin, ALAN R. BRASH, Marcia E. Newcomer	2012	129
11	The Structure of Human 15-Lipoxygenase-2 with a Substrate Mimic Journal of Biological Chemistry ·Matthew J. Kobe, David B. Neau, Caitlin E. Mitchell, Sue G. Bartlett, Marcia E. Newcomer	2014	121
12	The radius of gyration of L-arabinose-binding protein decreases upon binding of ligand. Journal of Biological Chemistry ·Marcia E. Newcomer, Barbara Lewis, Florante A. Quiocho	1981	106
13	The Prp19 U-box Crystal Structure Suggests a Common Dimeric Architecture for a Class of Oligomeric E3 Ubiquitin Ligases , Biochemistry ·Craig W. Vander Kooi, Melanie D. Ohi, Joshua A. Rosenberg, Michael L. Oldham, Marcia E. Newcomer, Kathleen L. Gould, Walter Chazin	2005	98
14	Insights from the X-ray Crystal Structure of Coral 8R-Lipoxygenase Journal of Biological Chemistry ·Michael L. Oldham, ALAN R. BRASH, Marcia E. Newcomer	2005	95
15	Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy Journal of Medicinal Chemistry ·Kin Sing Stephen Lee, Jun‐Yan Liu, Karen M Wagner, Svetlana V. Pakhomova, Hua Dong, Christophe H.P. Morisseau, Samuel H. Fu, Jun Yang	2014	90
16	The 1.85 Å Structure of an 8 R -Lipoxygenase Suggests a General Model for Lipoxygenase Product Specificity Biochemistry ·David B. Neau, Nathaniel C. Gilbert, Sue G. Bartlett, William E. Boeglin, ALAN R. BRASH, Marcia E. Newcomer	2009	88
17	The Structure of Retinal Dehydrogenase Type II at 2.7 Å Resolution: Implications for Retinal Specificity, Biochemistry ·Audrey L. Lamb, Marcia E. Newcomer	1999	85
18	Structure of the epididymal retinoic acid binding protein at 2.1 Å resolution Structure ·Marcia E. Newcomer	1993	82
19	Protein folding and three-dimensional domain swapping: astrained relationship? Current Opinion in Structural Biology ·Marcia E. Newcomer	2002	81
20	Mechanistic Diversity of Fosfomycin Resistance in Pathogenic Microorganisms Journal of the American Chemical Society ·Kerry L. Fillgrove, Svetlana V. Pakhomova, Marcia E. Newcomer, Richard Neil Armstrong	2003	81

About Marcia E. Newcomer

Marcia E. Newcomer is a scholar working on Molecular Biology, Biochemistry, Pharmacology, Cell Biology and Biochemistry, having authored 105 papers that have together received 6.1k indexed citations. Recurring topics across this work include Retinoids in leukemia and cellular processes (22 papers), Enzyme Structure and Function (18 papers), Biotin and Related Studies (12 papers), Microbial Natural Products and Biosynthesis (10 papers), Inflammatory mediators and NSAID effects (9 papers), Biochemical and Molecular Research (8 papers), Antioxidant Activity and Oxidative Stress (8 papers) and Amino Acid Enzymes and Metabolism (8 papers). The work is most often cited by research in Biochemistry (575 citations), Biochemistry (370 citations), Toxicology (183 citations), Molecular Biology (3.6k citations) and Molecular Medicine (202 citations). Marcia E. Newcomer has collaborated with scholars based in United States, Sweden and Germany. Frequent co-authors include T. Alwyn Jones, ALAN R. BRASH, Nathaniel C. Gilbert, Sandra W. Cowan, David B. Neau, Sue G. Bartlett, David Eng-Hui Ong, Svetlana V. Pakhomova, William E. Boeglin and Miroslav Z. Papiz. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry, Protein Science, Biochemical and Biophysical Research Communications and Journal of Molecular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Marcia E. Newcomer

Marcia E. Newcomer's Hit Papers

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