Leona E. Ling

7.2k citations

57 papers · 6.1k · 1 hit paper · h-index 30

Impact in

Immunology top 1%
- Immune cells in cancer
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune Cell Function and Interaction
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
Oncology top 2%
- Cancer Immunotherapy and Biomarkers
- Cancer Cells and Metastasis

Papers in

Oncology 21
- Cytokine Signaling Pathways and Interactions 6
- Cancer Immunotherapy and Biomarkers 5
Radiology, Nuclear Medicine and Imaging 16
- Monoclonal and Polyclonal Antibodies Research 15

Co-authors: Steven M Albelda (5 shared papers)Veena Kapoor (4 shared papers)Jing Sun (2 shared papers)SAMUEL C. KIM (2 shared papers)Guanjun Cheng (2 shared papers)George Scott Worthen (1 shared paper)Zvi Gregorio Fridlender (1 shared paper)Michael J. Corbley (7 shared papers)
Journals: Neurology (8 papers)Bioorganic & Medicinal Chemistry Letters (6 papers)American Journal of Obstetrics and Gynecology (5 papers)Proceedings of the National Academy of Sciences (3 papers)Clinical Cancer Research (2 papers)
Partner nations: United States Belgium Germany

In The Last Decade

Leona E. Ling

57 papers receiving 5.9k citations

Leona E. Ling's Hit Papers

align trajectories log scale

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN 2009 · 2.8k citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2009 Cancer Cell

Peers

Countries citing papers authored by Leona E. Ling

Since Specialization

Citations

This map shows the geographic impact of Leona E. Ling's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leona E. Ling with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leona E. Ling more than expected).

Fields of papers citing papers by Leona E. Ling

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leona E. Ling. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leona E. Ling. The network helps show where Leona E. Ling may publish in the future.

Co-authors

The 25 scholars most cited alongside Leona E. Ling, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Leona E. Ling Line = papers co-authored together Leona E. Ling links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 57 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN Cancer Cell ·Zvi Gregorio Fridlender, Jing Sun, SAMUEL C. KIM, Veena Kapoor, Guanjun Cheng, Leona E. Ling, George Scott Worthen, Steven M Albelda Hit paper breakdown →	2009	2808
2	The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors Nature Medicine ·Roberto Pola, Leona E. Ling, Marcy Silver, Michael J. Corbley, Marianne Kearney, R. Blake Pepinsky, Renee I. Shapiro, Frederick R. Taylor	2001	524
3	Osteopontin N-terminal Domain Contains a Cryptic Adhesive Sequence Recognized by α9β1 Integrin Journal of Biological Chemistry ·Laura L. Smith, Hung-Kam Cheung, Leona E. Ling, John Li Chen, Dean Sheppard, Robert Pytela, Cecilia M. Giachelli	1996	226
4	Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity Proceedings of the National Academy of Sciences ·Nathaniel Washburn, Inessa Schwab, Daniel F. Ortiz, Naveen Bhatnagar, Jonathan C. Lansing, Amy Medeiros, Steven M. Tyler, Divya J. Mekala	2015	196
5	Conditional Disruption of Hedgehog Signaling Pathway Defines its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology ·Li‐Chun Wang, Zhong–Ying Liu, Renee I. Shapiro, Jianliang Yang, Irene Sizing, Paul Rayhorn, Ellen A. Garber, Chris D. Benjamin	2000	176
6	Postnatal Recapitulation of Embryonic Hedgehog Pathway in Response to Skeletal Muscle Ischemia Circulation ·Roberto Pola, Leona E. Ling, Tamar R. Aprahamian, Elena Barban, Marta Bosch‐Marcé, Cynthia J. Curry, Michael J. Corbley, Marianne Kearney	2003	166
7	Successful shape-Based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI) Bioorganic & Medicinal Chemistry Letters ·Juswinder Singh, Claudio E. Chuaqui, P. Ann Boriack‐Sjodin, Wen‐Cherng Lee, Timothy W. Pontz, Michael J. Corbley, Hung Kam Cheung, Robert M. Arduini	2003	150
8	M281, an Anti‐FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First‐in‐Human Study Clinical Pharmacology & Therapeutics ·Leona E. Ling, Jan Hillson, Renger G. Tiessen, Tjerk Bosje, Mattheus Paulus van Iersel, Darrell J. Nix, Lynn Markowitz, Nicholas A. Cilfone	2018	127
9	Small Molecular Inhibitor of Transforming Growth Factor-β Protects Against Development of Radiation-Induced Lung Injury International Journal of Radiation OncologyBiologyPhysics ·Mitchell Steven Anscher, Bradley A. Thrasher, Larisa Zgonjanin, Zahid N. Rabbani, Michael J. Corbley, Kai Fu, Lihong Sun, Wen‐Cherng Lee	2008	118
10	The amino-terminal region of Tyk2 sustains the level of interferon α receptor 1, a component of the interferon α/β receptor Proceedings of the National Academy of Sciences ·Maria Cristina Gauzzi, Giovanna Barbieri, Marc François Richter, Gilles Uzé, Leona E. Ling, Marc Mardoche Fellous, Sandra Pellegrini	1997	108
11	Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment Journal of Clinical Investigation ·Brent Allen Hanks, Alisha Holtzhausen, Katherine S. Evans, Rebekah Jamieson, Petra Gimpel, Olivia M. Campbell, Melissa Hector-Greene, Lihong Sun	2013	101
12	A Novel Small-Molecule Inhibitor of Transforming Growth Factor β Type I Receptor Kinase (SM16) Inhibits Murine Mesothelioma Tumor Growth In vivo and Prevents Tumor Recurrence after Surgical Resection Cancer Research ·Eiji Suzuki, Samuel Kim, Hung Kam Cheung, Michael J. Corbley, Xiamei Zhang, Lihong Sun, Feng Shan, Juswinder Singh	2007	98
13	Intracellular TGF-β Receptor Blockade Abrogates Smad-Dependent Fibroblast Activation In Vitro and In Vivo Journal of Investigative Dermatology ·Wataru Ishida, Yasuji Mori, Gabriella Lakos, Lihong Sun, Feng Shan, Scott Bowes, Serene Josiah, Wen‐Cherng Lee	2006	80
14	Sonic hedgehog restricts adhesion and migration of neural crest cells independently of the Patched- Smoothened-Gli signaling pathway Proceedings of the National Academy of Sciences ·Sandrine Testaz, Artem Jarov, Kevin P. Williams, Leona E. Ling, Victor Koteliansky, Claire Fournier‐Thibault, Jean‐Loup Duband	2001	78
15	SM16, an Orally Active TGF-β Type I Receptor Inhibitor Prevents Myofibroblast Induction and Vascular Fibrosis in the Rat Carotid Injury Model Arteriosclerosis Thrombosis and Vascular Biology ·Kai Fu, Michael J. Corbley, Lihong Sun, Jessica E. Friedman, Feng Shan, James L. Papadatos, Donald E. Costa, Frank Lutterodt	2008	76
16	Systemic Blockade of Transforming Growth Factor-β Signaling Augments the Efficacy of Immunogene Therapy Cancer Research ·SAMUEL C. KIM, George Buchlis, Zvi G. Fridlender, Jing Sun, Veena Kapoor, Guanjun Cheng, Andrew R. Haas, Hung Kam Cheung	2008	73
17	Disruption of hedgehog signaling reveals a novel role in intestinal morphogenesis and intestinal-specific lipid metabolism in mice Gastroenterology ·Li‐Chun Wang, Fatiha Nassir, Zhong–Ying Liu, Leona E. Ling, Frank C. Kuo, Thomas Crowell, Dian L. Olson, Nicholas O. Davidson	2002	73
18	Transforming Growth Factor-β Receptor Blockade Augments the Effectiveness of Adoptive T-Cell Therapy of Established Solid Cancers Clinical Cancer Research ·Africa F. Wallace, Veena Kapoor, Jing Sun, Paul Mrass, Wolfgang Weninger, Daniel F. Heitjan, Carl H. June, Larry R. Kaiser	2008	68
19	Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors Science Translational Medicine ·Daniel F. Ortiz, Jonathan C. Lansing, Laura I. Rutitzky, Elma Kurtagic, Thomas Prod’homme, Amit Choudhury, Nathaniel Washburn, Naveen Bhatnagar	2016	61
20	The small molecule TGF-β signaling inhibitor SM16 synergizes with agonistic OX40 antibody to suppress established mammary tumors and reduce spontaneous metastasis Cancer Immunology Immunotherapy ·Kendra C. Garrison, Tobias Hahn, Wen‐Cherng Lee, Leona E. Ling, Andrew D. Weinberg, Emmanuel T. Akporiaye	2011	59

About Leona E. Ling

Leona E. Ling is a scholar working on Oncology, Radiology, Nuclear Medicine and Imaging, Immunology, Molecular Biology and Immunology and Allergy, having authored 57 papers that have together received 6.1k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (15 papers), TGF-β signaling in diseases (9 papers), Cytokine Signaling Pathways and Interactions (6 papers), Hedgehog Signaling Pathway Studies (6 papers), Myasthenia Gravis and Thymoma (5 papers), Cancer Immunotherapy and Biomarkers (5 papers), Cell Adhesion Molecules Research (4 papers) and Immunodeficiency and Autoimmune Disorders (3 papers). The work is most often cited by research in Immunology (2.5k citations), Oncology (1.9k citations), Immunology and Allergy (262 citations), Molecular Biology (2.4k citations) and Cancer Research (469 citations). Leona E. Ling has collaborated with scholars based in United States, Belgium and Germany. Frequent co-authors include Steven M Albelda, Veena Kapoor, Jing Sun, SAMUEL C. KIM, Guanjun Cheng, George Scott Worthen, Zvi Gregorio Fridlender, Michael J. Corbley, Wen‐Cherng Lee and Jeffrey M. Isner. Their work appears in journals such as Neurology, Bioorganic & Medicinal Chemistry Letters, American Journal of Obstetrics and Gynecology, Proceedings of the National Academy of Sciences and Clinical Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Leona E. Ling

Impact in

Papers in i

In The Last Decade

Leona E. Ling

Leona E. Ling's Hit Papers

Peers

Countries citing papers authored by Leona E. Ling

Fields of papers citing papers by Leona E. Ling

All Works

About Leona E. Ling

Explore authors with similar magnitude of impact

Papers in