Ny Sin

3.0k citations

20 papers · 2.0k · 2 hit papers · h-index 14

Impact in

Oncology top 5%
- Peptidase Inhibition and Analysis
Molecular Biology top 5%
- Ubiquitin and proteasome pathways
- Protein Degradation and Inhibitors
- Chemical Synthesis and Analysis
- Glycosylation and Glycoproteins Research

Papers in

Organic Chemistry 7
- Carbohydrate Chemistry and Synthesis 3
Molecular Biology 6
- Ubiquitin and proteasome pathways 4

Co-authors: Craig M. Crews (7 shared papers)Lihao Meng (5 shared papers)Benjamin H. Kwok (3 shared papers)Mikael Elofsson (2 shared papers)Royce Mohan (1 shared paper)James Wen (1 shared paper)William G. Bornmann (1 shared paper)Kyung Bo Kim (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (5 papers)Proceedings of the National Academy of Sciences (2 papers)Tetrahedron Letters (2 papers)Magnetic Resonance in Chemistry (1 paper)Microchemical Journal (1 paper)
Partner nations: United States Germany

In The Last Decade

Ny Sin

19 papers receiving 1.9k citations

Ny Sin's Hit Papers

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Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity 1999 · 802 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1999 Proceedings of the National Academy of Sciences
1997 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Ny Sin

Since Specialization

Citations

This map shows the geographic impact of Ny Sin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ny Sin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ny Sin more than expected).

Fields of papers citing papers by Ny Sin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ny Sin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ny Sin. The network helps show where Ny Sin may publish in the future.

Co-authors

The 25 scholars most cited alongside Ny Sin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ny Sin Line = papers co-authored together Ny Sin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity Proceedings of the National Academy of Sciences ·Lihao Meng, Royce Mohan, Benjamin H. Kwok, Mikael Elofsson, Ny Sin, Craig M. Crews Hit paper breakdown →	1999	802
2	The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2 Proceedings of the National Academy of Sciences ·Ny Sin, Lihao Meng, Margaret Q. W. Wang, James Wen, William G. Bornmann, Craig M. Crews Hit paper breakdown →	1997	533
3	Total synthesis of the-potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology Bioorganic & Medicinal Chemistry Letters ·Ny Sin, Kyung Bo Kim, Mikael Elofsson, Lihao Meng, Hak Auth, Benjamin H. Kwok, Craig M. Crews	1999	163
4	Eponemycin exerts its antitumor effect through the inhibition of proteasome function. PubMed ·Lin Meng, Benjamin H. Kwok, Ny Sin, Craig M. Crews	1999	132
5	Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: Insights into specificity and potency Bioorganic & Medicinal Chemistry Letters ·Kyung Bo Kim, Jayhyuk Myung, Ny Sin, Craig M. Crews	1999	103
6	Oral Efficacy of a Respiratory Syncytial Virus Inhibitor in Rodent Models of Infection Antimicrobial Agents and Chemotherapy ·Christopher Cianci, Eugene V. Genovesi, Lucinda Lamb, Ivette Medina, Zheng Yang, Lisa Zadjura, Hyekyung Yang, Celia D’Arienzo, Ny Sin, Kuo‐Long Yu, Keith D. Combrink, Zhufang Li, Richard J. Colonno, Nicholas A. Meanwell, Junius M. Clark, Mark Krystal	2004	58
7	Eponemycin analogues: syntheses and use as probes of angiogenesis Bioorganic & Medicinal Chemistry ·Ny Sin, Lihao Meng, Hak Auth, Craig M. Crews	1998	50
8	Respiratory syncytial virus fusion inhibitors. Part 7: Structure–activity relationships associated with a series of isatin oximes that demonstrate antiviral activity in vivo Bioorganic & Medicinal Chemistry Letters ·Ny Sin, Brian L. Venables, Keith D. Combrink, H. Belgin Gülgeze, Kuo‐Long Yu, Rita L. Civiello, Jan Willem Thuring, X. Alan Wang, Zheng Yang, Lisa Zadjura, Anthony M. Marino, Kathleen F. Kadow, Christopher Cianci, Junius Clarke, Eugene V. Genovesi, Ivette Medina, Lucinda Lamb, Mark Krystal, Nicholas A. Meanwell	2009	36
9	The Antiproliferative Agent Didemnin B Uncompetitively Inhibits Palmitoyl Protein Thioesterase Biochemistry ·Lihao Meng, Ny Sin, Craig M. Crews	1998	31
10	Inhibitors of HIV-1 maturation: Development of structure–activity relationship for C-28 amides based on C-3 benzoic acid-modified triterpenoids Bioorganic & Medicinal Chemistry Letters ·Jacob J. Swidorski, Zheng Liu, Sing‐Yuen Sit, Jie Chen, Yan Chen, Ny Sin, Brian L. Venables, Dawn D. Parker, Beata Nowicka-Sans, Brian Terry, Tricia Protack, Sandhya Rahematpura, Umesh Hanumegowda, Susan Jenkins, Mark Krystal, Ira B. Dicker, Nicholas A. Meanwell, Alicia Regueiro‐Ren	2016	26
11	The design, synthesis and structure-activity relationships associated with C28 amine-based betulinic acid derivatives as inhibitors of HIV-1 maturation Bioorganic & Medicinal Chemistry Letters ·Yan Chen, Sing‐Yuen Sit, Jie Chen, Jacob J. Swidorski, Zheng Liu, Ny Sin, Brian L. Venables, Dawn D. Parker, Beata Nowicka-Sans, Zeyu Lin, Zhufang Li, Brian Terry, Tricia Protack, Sandhya Rahematpura, Umesh Hanumegowda, Susan Jenkins, Mark Krystal, Ira Dicker, Nicholas A. Meanwell, Alicia Regueiro‐Ren	2018	18
12	Diastereoselective [2,3] Wittig rearrangement of carbohydrate-derived tertiary allylic ethers. 2. Synthesis of an advanced rapamycin intermediate from D-glucose. Tetrahedron Letters ·Ny Sin, James Kallmerten	1993	16
13	Synthesis of (2S,3S,8S,9S)-Adda from D-glucose Tetrahedron Letters ·Ny Sin, James Kallmerten	1996	15
14	The alkylation of isatin‐derived oximes: Spectroscopic and X‐ray crystallographic structural characterization of oxime and nitrone products Journal of Heterocyclic Chemistry ·Ny Sin, Brian L. Venables, Xiaohong Liu, Stella Huang, Qi Gao, Alicia Ng, R. A. Dalterio, Ramkumar Rajamani, Nicholas A. Meanwell	2009	14
15	¹⁵N chemical shifts of a series of isatin oxime ethers and their corresponding nitrone isomers Magnetic Resonance in Chemistry ·(unknown), Xiaohua Huang, Ny Sin, Brian L. Venables, Vikram Roongta	2010	4
16	Molecular mechanics as an organic chemistry laboratory exercise Journal of Chemical Education ·Ronald M. Jarret, Ny Sin	1990	4
17	The use of IR spectroscopy to monitor the conversion of matrix isolated phenylacetyl chloride to phenylacetyl cation, without decarbonylation to benzyl cation Journal of Physical Organic Chemistry ·Ronald M. Jarret, Ny Sin, Timothy M. Ramsey, Martin Saunders	1989	3
18	Deuterium Isotope Effects on13C NMR Chemical Shifts of Amides Microchemical Journal ·Ronald M. Jarret, Ny Sin, Matthew R. Dintzner	1997	2
19	Silver Benzoate Facilitates the Copper-Catalyzed C–N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles ACS Omega ·Cedric Lozano, Cristián Ramírez, Ny Sin, Hélène M.-F. Viart, Stanley B. Prusiner, Nick A. Paras, Jay C. Conrad	2021	1
20	Preclinical Profile of the HIV-1 Maturation Inhibitor VH3739937 Viruses ·Brian McAuliffe, Paul Falk, Jie Chen, Yan Chen, Sing‐Yuen Sit, Jacob J. Swidorski, Richard A. Hartz, Li Xu, Brian L. Venables, Ny Sin, Nicholas A. Meanwell, Alicia Regueiro‐Ren, David Wensel, Umesh Hanumegowda, Mark Krystal	2024	0

About Ny Sin

Ny Sin is a scholar working on Organic Chemistry, Molecular Biology, Oncology, Infectious Diseases and Cancer Research, having authored 20 papers that have together received 2.0k indexed citations. Recurring topics across this work include Peptidase Inhibition and Analysis (6 papers), Ubiquitin and proteasome pathways (4 papers), HIV/AIDS drug development and treatment (3 papers), Carbohydrate Chemistry and Synthesis (3 papers), HIV Research and Treatment (3 papers), Virology and Viral Diseases (2 papers), Electron Spin Resonance Studies (2 papers) and Hepatitis C virus research (2 papers). The work is most often cited by research in Oncology (703 citations), Molecular Biology (1.4k citations), Cancer Research (201 citations), Cell Biology (188 citations) and Hematology (107 citations). Ny Sin has collaborated with scholars based in United States and Germany. Frequent co-authors include Craig M. Crews, Lihao Meng, Benjamin H. Kwok, Mikael Elofsson, Royce Mohan, James Wen, William G. Bornmann, Kyung Bo Kim, Lin Meng and Jayhyuk Myung. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Proceedings of the National Academy of Sciences, Tetrahedron Letters, Magnetic Resonance in Chemistry and Microchemical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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