Ken Itoh

40.4k citations
256 papers · 35.4k · 15 hit papers · h-index 80

Impact in

    • Genomics, phytochemicals, and oxidative stress
    • Glutathione Transferases and Polymorphisms
    • Heme Oxygenase-1 and Carbon Monoxide
    • Redox biology and oxidative stress

Papers in

    • Genomics, phytochemicals, and oxidative stress 115
    • Glutathione Transferases and Polymorphisms 52
    • Redox biology and oxidative stress 10
    • Heme Oxygenase-1 and Carbon Monoxide 8
    • Biochemical effects in animals 8

Ken Itoh

248 papers receiving 34.7k citations

Ken Itoh's Hit Papers

Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology 2020 · 428 citations
4280+10+20Years since publication10002.0k3.0k

Peers

Ken Itoh
Comparison fields: 5 of 164
  • Molecular Biology 26.4k
  • Biological Psychiatry 757
  • Biochemistry 1.8k
  • Biochemistry 1.9k
  • Aging 405
Replace Albena T. Dinkova‐Kostova with:
Albena T. Dinkova‐Kostova United States
Thomas W. Kensler United States
John D. Hayes United Kingdom
Salvatore Cuzzocrea Italy
Henry Jay Forman United States
Pál Pacher United States
Nobunao Wakabayashi United States
Hozumi Motohashi Japan
Wulf Dröge Germany
Gökhan S. Hotamışlıgil United States
Ken Itoh relative to Albena T. Dinkova‐Kostova United States Albena T. Dinkova‐Kostova's profile →
Citations per field
00.5×1.5×
Albena T. Dinkova‐Kostova · 1×
Citations per year

Countries citing papers authored by Ken Itoh

Since Specialization
Citations

This map shows the geographic impact of Ken Itoh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ken Itoh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ken Itoh more than expected).

Fields of papers citing papers by Ken Itoh

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ken Itoh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ken Itoh. The network helps show where Ken Itoh may publish in the future.

Co-authors

The 25 scholars most cited alongside Ken Itoh, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ken Itoh Line = papers co-authored together Ken Itoh links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 256 papers — load more, or switch the sort, to bring in the rest.

#Work
1
An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
Hit paper breakdown →
19973476
2
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
Hit paper breakdown →
19993131
3
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
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20021680
4
Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages
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20001333
5
Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression
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2003996
6
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
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2001980
7
Molecular mechanism activating nrf2–keap1 pathway in regulation of adaptive response to electrophiles
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2004782
8
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
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2003761
9
Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles
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2003729
10
Keap1 Recruits Neh2 through Binding to ETGE and DLG Motifs: Characterization of the Two-Site Molecular Recognition Model
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2006635
11
Modulation of Gene Expression by Cancer Chemopreventive Dithiolethiones through the Keap1-Nrf2 Pathway
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2003600
12
The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
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2001578
13
Bach Proteins Belong to a Novel Family of BTB-Basic Leucine Zipper Transcription Factors That Interact with MafK and Regulate Transcription through the NF-E2 Site
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1996562
14
Enhanced Expression of the Transcription Factor Nrf2 by Cancer Chemopreventive Agents: Role of Antioxidant Response Element-Like Sequences in the nrf2 Promoter
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2002531
15 2002468
16 2010461
17 2001460
18
Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology
Hit paper breakdown →
2020428
19 2006428
20 2003420

About Ken Itoh

Ken Itoh is a scholar working on Molecular Biology, Physiology, Immunology, Plant Science and Cell Biology, having authored 256 papers that have together received 35.4k indexed citations. Recurring topics across this work include Genomics, phytochemicals, and oxidative stress (115 papers), Glutathione Transferases and Polymorphisms (52 papers), Redox biology and oxidative stress (10 papers), Free Radicals and Antioxidants (10 papers), Air Quality and Health Impacts (9 papers), Heme Oxygenase-1 and Carbon Monoxide (8 papers), Biochemical effects in animals (8 papers) and Endoplasmic Reticulum Stress and Disease (8 papers). The work is most often cited by research in Molecular Biology (26.4k citations), Biological Psychiatry (757 citations), Biochemistry (1.8k citations), Biochemistry (1.9k citations) and Aging (405 citations). Ken Itoh has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Masayuki Yamamoto, Yasutake Katoh, Tetsuro Ishii, Nobunao Wakabayashi, Kazuhiko Igarashi, John D. Hayes, Satoru Takahashi, Michael McMahon, Norio Hayashi and Thomas W. Kensler. Their work appears in journals such as Journal of Biological Chemistry, Journal of Pediatric Gastroenterology and Nutrition, Molecular and Cellular Biology, Genes to Cells and Biochemical and Biophysical Research Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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