John Silke

38k citations
234 papers · 31.5k · 12 hit papers · h-index 86

Impact in

    • Cell death mechanisms and regulation
    • Inflammasome and immune disorders
    • Ubiquitin and proteasome pathways
    • Extracellular vesicles in disease
    • NF-κB Signaling Pathways

Papers in

    • Cell death mechanisms and regulation 130
    • Ubiquitin and proteasome pathways 18
    • Inflammasome and immune disorders 11
    • Epigenetics and DNA Methylation 7
    • NF-κB Signaling Pathways 36

John Silke

230 papers receiving 31.1k citations

John Silke's Hit Papers

Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity 2024 · 270 citations
2700+8+17Years since publication1k2k3k4k5k

Peers

John Silke
Comparison fields: 5 of 138
  • Molecular Biology 19.5k
  • Cancer Research 2.8k
  • Immunology 2.9k
  • Oncology 2k
  • Cell Biology 881
Replace Henning Walczak with:
Henning Walczak Germany
Manolis Pasparakis Germany
Marcus E. Peter United States
David C.S. Huang Australia
Ulf Rüdiger Rapp Germany
Domagoj Vucic Germany
Karen M. O’Rourke United States
Fabio Martinon Switzerland
David Wallach Israel
Justin R. Cross United States
John Silke relative to Henning Walczak Germany Henning Walczak's profile →
Citations per field
00.5×1.5×
Henning Walczak · 1×
Citations per year

Countries citing papers authored by John Silke

Since Specialization
Citations

This map shows the geographic impact of John Silke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Silke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Silke more than expected).

Fields of papers citing papers by John Silke

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Silke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Silke. The network helps show where John Silke may publish in the future.

Co-authors

The 25 scholars most cited alongside John Silke, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John Silke Line = papers co-authored together John Silke links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 234 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Hit paper breakdown →
20185362
2
Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins
Hit paper breakdown →
20001983
3
The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
Hit paper breakdown →
20131063
4
IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis
Hit paper breakdown →
2007944
5
Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach
Hit paper breakdown →
2006919
6
Linear ubiquitination prevents inflammation and regulates immune signalling
Hit paper breakdown →
2011790
7 2009658
8
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
Hit paper breakdown →
2015574
9
RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis
Hit paper breakdown →
2014525
10 2005521
11
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
Hit paper breakdown →
2014521
12 2002497
13 2015461
14 2002460
15 2013454
16 2012438
17 2009395
18 1999358
19 2012330
20 2017310

About John Silke

John Silke is a scholar working on Molecular Biology, Cancer Research, Immunology, Oncology and Cell Biology, having authored 234 papers that have together received 31.5k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (130 papers), NF-κB Signaling Pathways (36 papers), Ubiquitin and proteasome pathways (18 papers), Inflammasome and immune disorders (11 papers), T-cell and B-cell Immunology (10 papers), Immune Response and Inflammation (10 papers), Cancer Immunotherapy and Biomarkers (7 papers) and Epigenetics and DNA Methylation (7 papers). The work is most often cited by research in Molecular Biology (19.5k citations), Cancer Research (2.8k citations), Immunology (2.9k citations), Oncology (2k citations) and Cell Biology (881 citations). John Silke has collaborated with scholars based in Australia, United States and Germany. Frequent co-authors include David Lawrence Vaux, Paul G. Ekert, James Edward Vince, Anne M. Verhagen, Miha Pakusch, Wendy Wei-Lynn Wong, Richard J. Simpson, Robert L. Moritz, Holly Anderton and James A. Rickard. Their work appears in journals such as Cell Death and Differentiation, Nature Communications, Journal of Biological Chemistry, Nature and The EMBO Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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